Conserved Protein Domain Family
lytR_cpsA_psr

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TIGR00350: lytR_cpsA_psr 
cell envelope-related function transcriptional attenuator common domain
This model describes a domain of unknown function that is found in the predicted extracellular domain of a number of putative membrane-bound proteins. One of these is proteins psr, described as a penicillin binding protein 5 (PDP-5) synthesis repressor. Another is Bacillus subtilis LytR, described as a transcriptional attenuator of itself and the LytABC operon, where LytC is N-acetylmuramoyl-L-alanine amidase. A third is CpsA, a putative regulatory protein involved in exocellular polysaccharide biosynthesis. Besides the region of strong similarily represented by this model, these proteins share the property of having a short putative N-terminal cytoplasmic domain and transmembrane domain forming a signal-anchor. [Regulatory functions, Other]
Statistics
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PSSM-Id: 273029
Aligned: 7 rows
Threshold Bit Score: 204.913
Created: 7-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
CAA19232     108 ARSDTAMVMHIPEGRTEAVAVSIPRDTLVTRPECRKQdgte----------------taaAKRVMFNSIYSQVGPACVVK 171 Streptomyces co...
CAA20411     122 ARSDTAMVVHLDAGRTAATVVSIPRDTLVERPSCPLPsggt----------------traASGAMFNTAYELGGPVCAVK 185 Streptomyces co...
Q02115        82 GRADTLIYMTVNPKTNTTDMVSIPRDTYTKIIGKGTM--------------------------DKINHSYAFGGTQMTVD 135 Bacillus subtil...
CCU60633      94 GRSDSLIVVTLDPKNKTMKMLSIPRDTRVQLAGDTTG------------------------SKTKINAAYSKGGKDETVE 149 Bacillus subtil...
WP_003903190  69 ARSDTVMLVNIPASRERVVAVSFPRDLAITPIQCEAWnpetgkygpiydektgtmgprlvYTETKLNSAFSFGGPKCLVK 148 Mycobacterium t...
WP_010889205  96 PNTDTLMVVKVSP--AGINVLNIPRDTTVGDYSYRIP-----------------------AAEQKINSKYWSGGPQALTR 150 Deinococcus rad...
WP_010872845 124 GLTDTMVLIRLDPKEKSLVVLSIPRDTRVEIPGYSGA--------------------------RKINQANALGGPALAAM 177 Synechocystis s...
CAA19232     172 TVEQMSG-IRMDHYVEIDFAGFKDLVDAIGGVTVTVDQD---IHD----PSSG--LDLTAGTHKLNGTDSLAFVRTRHGV 241 Streptomyces co...
CAA20411     186 TVESLTG-VRMDHYVEVDFSGFADLVDALGGVTVTTDVD---IDD----DKSH--LHLDAGTHHLDGTEALGLARTRYGL 255 Streptomyces co...
Q02115       136 TVENFLD-VPVDYFVKVNMESFRDVVDTLGGITVNSTFA---FSY----DGYS----FGKGEITLNGKEALAYTRMRKED 203 Bacillus subtil...
CCU60633     150 TVENFLQ-IPIDKYVTVDFDGFKDVINEVGGIDVDVPFD---FDEksdvDESKr-IYFKKGEMHLNGEEALAYARMRKQD 224 Bacillus subtil...
WP_003903190 149 VIQKLSG-LSINRFIAIDFVGFARMVEALGGVEVCSTTP---LRD----YELGt-VLEHAGRQVIDGPTALNYVRARQVT 219 Mycobacterium t...
WP_010889205 151 AVEEVMG-EKVDSYVIVRTDYVERVIDALGGLDVTVPEPgieWVD----QAAGvdLKLAPGEHHLAGQEAVWYLRVRKGF 225 Deinococcus rad...
WP_010872845 178 TVTDLLGdVPIDRYIRVNVQAVEKLIDALGGVDVYVPRDm-kYQD----DSQRlyINLKEGQQRLDGEKALQMLRFRYDA 252 Synechocystis s...
CAA19232     242 Gd-GSDLGRIGLQQQFMLALLSEIKR 266 Streptomyces coelicolor A3(2)
CAA20411     256 Ag-GSDLARIELQHKLVKALLQQVSA 280 Streptomyces coelicolor A3(2)
Q02115       204 P--RGDFGRQDRQRQVIQGIINKGAN 227 Bacillus subtilis subsp. subtilis str. 168
CCU60633     225 K--RGDFGRNDRQKQILNALIDRMSS 248 Bacillus subtilis E1
WP_003903190 220 TesNGDYGRIKRQQLFLSSLLRSMIS 245 Mycobacterium tuberculosis
WP_010889205 226 G---DDYGRIDHQKQALTQLAGRLKS 248 Deinococcus radiodurans
WP_010872845 253 L---GDIGRIQRQQIVMRAVVEQALK 275 Synechocystis sp. PCC 6803
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