3WFQ


Conserved Protein Domain Family
HDIG
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TIGR00277: HDIG 
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HDIG domain
This domain is found in a few known nucleotidyltransferes and in a large number of uncharacterized proteins. It contains four widely separated His residues, the second of which is part of an invariant dipeptide His-Asp in a region matched approximately by the motif HDIG. This model may annotate homologous domains in which one or more of the His residues is conserved but misaligned, and some probable false-positive hits.
Links
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Statistics
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PSSM-Id: 272994
Aligned: 19 rows
Threshold Bit Score: 77.3759
Created: 7-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
3WFQ_E       284 LEQVIEDRAKYLSAELLENFgkkR----VlG--EftDVEL---LKWGALFHDIGKPQTfavREgkv-------------- 340 Aquifex aeolicu...
Q58188        14 CSENVVEHCLAVSEYAYELA---LaiknK-GyeV--DVEL---VRLGGLLHDIGRSRT---HG----------------- 64  Methanocaldococ...
P75506       296 FGQNVLSHCLETGFLTAYLA---L----LvN--F--KPDV---ALKCGLYHDIGKADD---ENg---------------- 342 Mycoplasma pneu...
P46344       497 ETPGTYHHSVMVANLSEAAC---E----AvG--A--NGLL---ARVGAYYHDLGKTKR---PQyfienqmnidnph-dkl 558 Bacillus subtil...
WP_010877546  66 RDEKLIKHCIATAAVMKSLA---R----ElG--E--DEEK---WWTIGILHDIDYEQT---QGd---------------- 112 Archaeoglobus f...
WP_010877275  11 CPEWVIDHSLAVRKKALELS---R----ElP--V--DMKL---VEEGAILHDIGRCRT---SGv---------------- 57  Methanothermoba...
KBU59153     223 QHKDVYQHSLTVLRQAIALE---D----D-G--P--DL-V---LRWAALLHDIGKPAT---RRhepdg------------ 271 Mycobacterium t...
AAA27495      17 LHQGGVHHLPAWDHTLSAVF---H----LlW--L--WPEApleARLAALFHDVGKPLT---RRfdpev------------ 70  Thermus thermop...
P54371       582 EAPGTFQHTLFVACLAESAA---R----ElR--C--NVEL---VRTGTLYHDIGKMHD---PLgfienqmggpnkhdein 644 Synechocystis s...
WP_014342523 629 TVSGTYNHTMMVATLAENAC---R----SiG--A--HSLL---ARVGAYYHDIGKMEN---GEyfvenqtgdskh--ldl 689 Treponema pallidum

3WFQ_E       341 -------tfYEHDKVGAQIVREIGERLRWGDEATEFVAK 372 Aquifex aeolicus VF5
Q58188        65 ---------IEHGVVGAEILRELGFDEKLALIAERHIGA 94  Methanocaldococcus jannaschii DSM 2661
P75506       343 --------kKNHTVTGAKIGDEFYFENDVKYTIANHHNK 373 Mycoplasma pneumoniae M129
P46344       559 spqlskniiISHTTDGANMLRSYKFPKELVDIAEQHHGT 597 Bacillus subtilis subsp. subtilis str. 168
WP_010877546 113 --------mEKHGLVGAEILLKEGVEEEIAEVVKRHNHM 143 Archaeoglobus fulgidus
WP_010877275  58 ----------EHAVEGARILEGFGYPPEVVRIVERHVGA 86  Methanothermobacter thermautotrophicus
KBU59153     272 -----gvsfHHHEVVGAKMVRKRMRALKYSKQMIDDISQ 305 Mycobacterium tuberculosis NRITLD54
AAA27495      71 ----grfrfLGHAEVGAEIARASLFWLRFPKEVVERAAG 105 Thermus thermophilus HB8
P54371       645 dpyvsvdiiKKHVSEGLVMARRYGLPQVVRDFIPEHQGQ 683 Synechocystis sp. PCC 6803 substr. Kazusa
WP_014342523 690 nprlsatviRSHVKLGVEKAHQLRLPQEVIDIIAEHHGN 728 Treponema pallidum
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