Conserved Protein Domain Family
xseA
?
TIGR00237: xseA 
exodeoxyribonuclease VII, large subunit
This family consist of exodeoxyribonuclease VII, large subunit XseA which catalyses exonucleolytic cleavage in either the 5'->3' or 3'->5' direction to yield 5'-phosphomononucleotides. Exonuclease VII consists of one large subunit and four small subunits. [DNA metabolism, Degradation of DNA]
Links
?
Statistics
?
PSSM-Id: 272979
Aligned: 264 rows
Threshold Bit Score: 255.436
Created: 7-Oct-2014
Updated: 25-Oct-2021
Structure
?
Aligned Rows:
Download Cn3D
PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
ZP_07271608   12 PVREVSRLIGDWVAR---LGEVWVEGQLTQISrRPG-ARVVFLTFRDssHD-----VSISLTCFRPVFDA-VAD------ 75  Streptomyces sp...
ZP_01732139   10 SVTGLTEYIKLLLEEdpqLIQVWVTGEVSSLH-EHR-VG-LFFTLSDsqGQ-----ATIKCVVWNSQKER-LLE------ 74  Cyanothece sp. ...
ZP_08492257   11 SVAGLTSYLQDLLEGdrnLQSVWLTGEVSNVS-HHP-SG-CFFTLCDtdKS-----AAIRCVVWNSQRQK-LVQ------ 75  Microcoleus vag...
ZP_05024718   26 SVAGLTDYIQELLEQdtqLQKVWVIGEVSSAN-RHR-SG-MFFTLRDleGK-----ASIQCVVWNSVLSK-LVQ------ 90  Coleofasciculus...
ZP_05037368   14 GVAGLTDYLKLLLEEdahLHKVWVVGEVSSAN-HHR-QG-CFFTLQEpdGS-----AAISCVVWKSQLPR-LTT------ 78  Synechococcus s...
ZP_03969162   12 SLLEVTKSIQKTIADr-yKSMYWIKAEMNKLN-HYThSGHCYPELVE--KKdgkivAEIRSILWKADYNR-INTnfmktv 86  Sphingobacteriu...
WP_014546966   9 SVTQYMRSLKNTVEAt---PAVWVHGVISQIA-EKK-SG-VYLSIADfaDGdvkpkATLALYCYTAKYDAiLAKisslsq 82  Fibrobacter suc...
WP_012694454  19 ELADVLTYVGQVIARg-vPGGVWVRAELVSVT-DRR---HLYLDLVQleDGve--vARCRATIWARERFS-LEGkfrkat 90  Deinococcus des...
WP_014022341   7 SLLSLNELIKRTLDSn-lSPTYWVIAEIGELR-AGV-RGHAYLDLIEkvDGni--lAKIRGNIWSYTYQS-ISRkfesvt 80  Cyclobacterium ...
WP_012163740  16 SVKGLTDYIQTLLEDdsyLVQVWVEGEVSSAA-RHR-SG-FFFTLQDqqEA-----ASIHCVIWNSYCDQ-LVI------ 80  Acaryochloris m...

ZP_07271608   76 --VVTEGSRIVVRAKPEWYQGRGSLSLRASEIRPV-GIGELLVKLERLKRELTAEGLFAADRKRPLPFLPRRIGLVTGRA 152 Streptomyces sp...
ZP_01732139   75 --LPKLGSEILVMGNVRLYAKKGEYQLTVSQVLAT-GEGLQALRYQQLKNRLASEGLFEKHLKRSLPSFPKIIAVVTATT 151 Cyanothece sp. ...
ZP_08492257   76 --IPAKGEQLLVLGSIRVYKNRGEYQLTVVQSLPA-GEGLQALRLQQLRSRLDAEGFFDPARKRPIPAHPQIVAVVTSDT 152 Microcoleus vag...
ZP_05024718   91 --LPQSGEQLIALGSIRIYPQRGQYQLMVWQALPG-GEGLQALRYNQLRQRLAAEGLFDAQNKRPLPTHPQTIAVVTSPQ 167 Coleofasciculus...
ZP_05037368   79 --APKVGEQVTVLGQIRLYPKRGTYQLTVWQVLPA-GEGLQALRYRRLRARLAAEGLFDEDRKRPLPAYPRMLAVVTSIQ 155 Synechococcus s...
ZP_03969162   87 rePLREGITMLFQASISYDPMYG-LSLKIVDIDPTfSLGELEKEKLESIQRLKEEGIYDLNKSLPFPVIPKRIAIISVET 165 Sphingobacteriu...
WP_014546966  83 pfTLKHDLKVNFLVRAELYIPYGKLQAQILDIDPVyTIGELALTKSAILKRLAMEGLLEKNKQLELADVPLRVGLITGEN 162 Fibrobacter suc...
WP_012694454  91 ggTLTAGVKVLLFCTAEFHAQYG-FSLNVIDIAPEfTLGDAALKLGALRQALLLEGVYGLNRLLPAPSDFTRVAVIAPVE 169 Deinococcus des...
WP_014022341  81 gtSLQAGMNIMALVSVQFHELYG-ISLVIKDVDPNfTLGERARKRQEIIGRLTNEGLMDLNKQYVLPVVSQKIAIISSVT 159 Cyclobacterium ...
WP_012163740  81 --EPEVGEQILALGRIRVYPQRGQYQLMAWQLFPA-GEGLRSLRYQQLRERLTREGLFDPLQKQALPTYPQTVGVVTSHQ 157 Acaryochloris m...

ZP_07271608  153 SAAERDVIKNAEAR-WPA-VRFETREVAVQGVHAVSQVVGAVKELDAHPD---VDVIVVARGGGSVEDLLPFSDAELIRT 227 Streptomyces sp...
ZP_01732139  152 AAAWGDIQKTLSHR-NPG-VKVLFSPATVQGKEAPSSIVKAIERVNIDGR---AELIILARGGGAVEDLFCFNDERVVRA 226 Cyanothece sp. ...
ZP_08492257  153 GAAWGDIQRTLAQR-YPG-LRVLLSPTGVQGELAAAAIARAIARVELDGR---ADVIILGRGGGSAEDLACFNDERVVRA 227 Microcoleus vag...
ZP_05024718  168 AAAWGDIRRTLRQR-YPG-LSVLFSPAQVQGDLAPESIVTAIERVERDGR---AELVILSRGGGASEDLVGFDDERVVRA 242 Coleofasciculus...
ZP_05037368  156 AAAWGDIQRTLVQR-SPG-LRVLLSPAVVQGPQAPASIAKAIARVDRDGR---ADVLMLARGGGAVEDLACFDDERVVMA 230 Synechococcus s...
ZP_03969162  166 SKGLSDFYKIIHQNpWGYrFECTLYPALLQGDKSVPSIIQQLSIVAEHQd--kYDVIAIIRGGGGEVGLSSYNNYLLARA 243 Sphingobacteriu...
WP_014546966 163 TAAYKDFTTRLEAS--PFaFEVTTIYARMQGNETEDSIIAALEQLQSDs---nLDVVCIVRGGGAKTDLNFFDSEALCRA 237 Fibrobacter suc...
WP_012694454 170 AAGLGDFRREADALeAAGlVRFEYLEATFQGREASASLTRAVEQARSMHVqepLDALVVIRGGGAVTDLAWLNDLDFARA 249 Deinococcus des...
WP_014022341 160 AAGYGDFINQLDQNsQEYkVHYRLFQAAMQGKDAIPQIIEAIHQIEEALIvekFDLLVIIRGGGAQTDLDCFDDYELAKT 239 Cyclobacterium ...
WP_012163740 158 AAAWGDIKRTLKAQ-HPG-LKVLFSPTKVQGKQAPEAIVLAIERVIKDGR---AEVLIVARGGGATEDLACFNDERVVRA 232 Acaryochloris m...

ZP_07271608  228 VAACRTPVVSAIGHEPDTPLLDLVADLRASTPTDAAKRVVPDVGEELERVRQTRDRARHAIRALVDREAHGLEQALAHSV 307 Streptomyces sp...
ZP_01732139  227 ISVSSIPIITGIGHQRDETLADLVADVNAHTPTAAAEMAVPSYEVMLIEHQQRKERLVASLKQRLRYESDQLASLKNR-- 304 Cyanothece sp. ...
ZP_08492257  228 IANCAIPIITGIGHERDESLADLVADKRAHTPTAAAAQAVPILADLYFEHKQRMVNLASAVRARFQTEEEHL-------- 299 Microcoleus vag...
ZP_05024718  243 IANCSIPVLTGIGHQRDESLADLVADFCAHTPTAAAERAVPELATLITEHQQRQEALHEAVTQHLDTSRNQLHQLKNR-L 321 Coleofasciculus...
ZP_05037368  231 IAASPIPVVTGIGHQRDESLADLVADACAHTPTAAAEMITPSLDELYQEQVNYLQRAGQVVARRLQHAQAQVQSLRTRLQ 310 Synechococcus s...
ZP_03969162  244 IAIFPLPVLTGIGHSTNLTVSEMVAYKNAITPSELADFLLQKFHNFAIPLDRATETIRNYSGLIFEQQAQKLNVFATDIR 323 Sphingobacteriu...
WP_014546966 238 VANYPTPVFTGIGHEIDRCLLDEVAYLSCITPTDCAKRLVERVTDSWNRMTEAMASIADGARDLLTENNKQLGTMGNQLQ 317 Fibrobacter suc...
WP_012694454 250 LATFPAPVITGLGHARDDTLPDEVASIRTDTPSKAAALIVRTVVQAAAQAQEDARTIRAHATQLLLDADAGATWAVDR-- 327 Deinococcus des...
WP_014022341 240 IANSSLPIITGIGHERDESIADLVAHTKLKTPTAVASFILSGFREFEDRLHRNLVSIERNVQARLKAEESGLTDKTHLLF 319 Cyclobacterium ...
WP_012163740 233 IAECPIPVISGIGHQRDETLADLVADVCAHTPTAAAE-CIPRLTDWQTDYRNCIARLYIILTRQLDVAHEHLLYQKTRLR 311 Acaryochloris m...

ZP_07271608  308 LRDP-YRLVAGRDEEIGAEIDRARRTVGHL----------------------LDRADSDLAHTLARVVALSPAATLRRGY 364 Streptomyces sp...
ZP_01732139  305 ---------------LKNLSVNAa---------------------------sIREARVKTLMLKEKLEALDPHAVLKRGF 342 Cyanothece sp. ...
ZP_08492257  300 ------QLLQNRLKRLPATSRTL------------------------------RQATGKLEVLQEKLSALNPAAVLQRGY 343 Microcoleus vag...
ZP_05024718  322 QRLPlNRQLQQEHHAIAQQRQRLIHSTSWR----------------------ISQATQHCQFLGQKLATLDPTNVLKRGY 379 Coleofasciculus...
ZP_05037368  311 RQRV-DRQLTQHQKSLVWQKQQLISAINQR----------------------LQHQQHQHQLLQEILVTLDPQAVLKRGY 367 Synechococcus s...
ZP_03969162  324 WTTQ--HMVEMAKNNIHILEKDLKAGFQQQ----------------------VKEQFSFLENTEKLLQLADPEHLLQRGF 379 Sphingobacteriu...
WP_014546966 318 QKVF--GLIQNEKSKHVLIAASIKKDTAFYikseherlnrnqeglkqgsrkiLDLAKSQFELVSEKVKNADPKTTLAKGY 395 Fibrobacter suc...
WP_012694454 328 -----A-----------------VQAARRA----------------------TDHAQAQTDALMRQALGLTPARTLARGY 363 Deinococcus des...
WP_014022341 320 NIFQ--NKLNKNNLLLERYAQQAKRSAIYKvdkerikndhlalnlrkvvdrkVNKSEERIRQIEKTIDRLNPETLLLRGY 397 Cyclobacterium ...
WP_012163740 312 RLQI-DRQFEREQVLRSRLQNHLLHAIKHR----------------------LGQAQQHQQLLQQQLTSLDPTQVLKRGY 368 Acaryochloris m...

ZP_07271608  365 AVLQRAdGAVVRAPEEIAADEELRARVAEGEFTVRRT 401 Streptomyces sp. SPB78
ZP_01732139  343 SVVRQTdGEIIRDSNQLIEGQELTIQLPQGTIKIKVT 379 Cyanothece sp. CCY0110
ZP_08492257  344 AAVIQSdGTIVRTTDGLEWGEELTVRLSRGVLKVKIV 380 Microcoleus vaginatus FGP-2
ZP_05024718  380 AVVRTEqGKIARNATSLVPGEELQIQLAEGQINVQVT 416 Coleofasciculus chthonoplastes PCC 7420
ZP_05037368  368 AIVKTa-GEIATDANQLPPGTELEIQLGKGKVKATVS 403 Synechococcus sp. PCC 7335
ZP_03969162  380 SITKIN-GQLLTSTTQVKPGDNISTRVQDGEISSTVH 415 Sphingobacterium spiritivorum ATCC 33300
WP_014546966 396 SLTLDEnGKFIRKASQLKSGDTIKTRLADGDVLSVVK 432 Fibrobacter succinogenes
WP_012694454 364 ALVRDAdGQPVTRAAQVGEAQDLTLEFHDGAVQVRSR 400 Deinococcus deserti
WP_014022341 398 TKTEKD-GLPIRG-QALGIGDELVTYTKLKKITSVIN 432 Cyclobacterium marinum
WP_012163740 369 ALVQTtdQQIVRSTQQLQVDQELKVELAEGHFTARVT 405 Acaryochloris marina
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap