3FOZ,3EPH


Conserved Protein Domain Family
miaA
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TIGR00174: miaA 
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tRNA dimethylallyltransferase
Alternate names include delta(2)-isopentenylpyrophosphate transferase, IPP transferase, 2-methylthio-N6-isopentyladenosine tRNA modification enzyme. Catalyzes the first step in the modification of an adenosine near the anticodon to 2-methylthio-N6-isopentyladenosine. Understanding of substrate specificity has changed. [Protein synthesis, tRNA and rRNA base modification]
Links
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Statistics
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PSSM-Id: 213512
Aligned: 9 rows
Threshold Bit Score: 407.159
Created: 7-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
3FOZ_A        12 AIFLMGPTASGKTALAIELRKILPVELISVDSALIYKGMDIGTAKPNAEELLAAPHRLLDIRDPSQAYSAADFRRDALAE 91  Escherichia col...
P16384        12 AIFLMGPTASGKTALAIELRKILPVELISVDSALIYKGMDIGTAKPNAEELLAAPHRLLDIRDPSQAYSAADFRRDALAE 91  Escherichia col...
P44495         5 AIFLMGPTASGKTDLAIQLRSQLPVEVISVDSALIYKGMDIGTAKPSKEELALAPHRLIDILDPSESYSAMNFRDDALRE 84  Haemophilus inf...
O31795         8 VVILVGPTAVGKTNLSIQLAKSLNAEIISGDSMQIYKGMDIGTAKITEQEMEGVPHHLIDILDPQDSFSTADYQSLVRNK 87  Bacillus subtil...
P74040         7 LIVICGTTASGKSQLALDLAQRLNAVILGADSRQIYKELDIGTAKPTLGDRQTVPHYLIDICEPTENFTLAEYQRQAQEL 86  Synechocystis s...
P07884        16 VIVIAGTTGVGKSQLSIQLAQKFNGEVINSDSMQVYKDIPIITNKHPLQEREGIPHHVMNHVDWSEEYYSHRFETECMNA 95  Saccharomyces c...
3EPH_A         4 VIVIAGTTGVGKSQLSIQLAQKFNGEVINSDSMQVYKDIPIITNKHPLQEREGIPHHVMNHVDWSEEYYSHRFETECMNA 83  baker's yeast
WP_010889830   6 VVFIFGPTAVGKSNILFHFPKNK-AEIINVDSIQVYKEFNIASSKPSKNLMKHIKHHLVDFLDPEKDYTIGIFYEQALKI 84  Lyme disease sp...
O25961        14 LIALLGPSGSGKSALSIELAQELDAEIFSLDSLSIYKDINIASAKPSLKERKNIKHYALDHLNIDEKNNAPLFKTLLEDA 93  Helicobacter py...

3FOZ_A        92 MADITAAGRIPLLVGGTMLYFKALLEGLSPLPSA-DPEVRARIEQQAAeQGWESLHRQLQEVDPVAAARIHPNDPQRLSR 170 Escherichia col...
P16384        92 MADITAAGRIPLLVGGTMLYFKALLEGLSPLPSA-DPEVRARIEQQAAeQGWESLHRQLQEVDPVAAARIHPNDPQRLSR 170 Escherichia col...
P44495        85 MADITAQGKIPLLVGGTMLYYKALIEGLSPLPSA-DENIRAELEQKAAqQGWAALHTELAKIDPISAARINPSDSQRINR 163 Haemophilus inf...
O31795        88 ISEIANRGKLPMIVGGTGLYIQSVLYDYTFTEEAnDPVFRESMQMAAErEGADFLHAKLAAADPEAAAAIHPNNTRRVIR 167 Bacillus subtil...
P74040        87 IASLN---QPILLVGGTGLYIQAIVKGLKIPAVP----PQTNLREQLAnLGQPFCYQLLSQVDPVAQSKIEPADVVRTLR 159 Synechocystis s...
P07884        96 IEDIHRRGKIPIVVGGTHYYLQTLFNKRVDTKSSeRKLTRKQLDILES-TDPDVIYNTLVKCDPDIATKYHPNDYRRVQR 174 Saccharomyces c...
3EPH_A        84 IEDIHRRGKIPIVVGGTHYYLQTLFNKRVDTKSSeRKLTRKQLDILES-TDPDVIYNTLVKCDPDIATKYHPNDYRRVQR 162 baker's yeast
WP_010889830  85 VKEIRQKKKIPIFVGGTAFYFKHLKDGFPSTPLVtSK-IRIYVNNLLElKGKSYLLKELKNVDPIRFNMLNKNDIYRIKR 163 Lyme disease sp...
O25961        94 MRVSSK--EILLIVGGSSFYLKSILEGLSRMPKLs---GEEVVKIEREiATLSNPYIFLKSIDPNMAFKIHPNDTYRTHK 168 Helicobacter py...

3FOZ_A       171 ALEVFFISGKTLTELTQTSGDALPYQVHQ-FAIApASRELLHQRIEQRFHQMLASGFEAEVRALFARGD-------Lh-- 240 Escherichia col...
P16384       171 ALEVFFISGKTLTELTQTSGDALPYQVHQ-FAIApASRELLHQRIEQRFHQMLASGFEAEVRALFARGD-------Lh-- 240 Escherichia col...
P44495       164 ALEVFYITGKSLTELTEEKGEALPYDFVQ-FAIApQDRHVLHERIEQRFHKMIELGFQAEVEKLYARGD-------Ln-- 233 Haemophilus inf...
O31795       168 ALEILHTSGKTMSQHLKEQKRELLYNAVL-IGLT-MDRDTLYERINQRVDLMMQSGLLPEVKRLYDKNV-------R--- 235 Bacillus subtil...
P74040       160 ALEVFYATGRPISSLQGENPP--SYPIVQ-IGLG-LEPEQLQPRIVHRTHAMVEAGLVKEVEGLINQYG-------E--- 225 Synechocystis s...
P07884       175 MLEIYYKTGKKPSETFNEQKITLKFDTLF-LWLY-SKPEPLFQRLDDRVDDMLERGALQEIKQLYEYYS-------Qnkf 245 Saccharomyces c...
3EPH_A       163 MLEIYYKTGKKPSETFNEQKITLKFDTLF-LWLY-SKPEPLFQRLDDRVDDMLERGALQEIKQLYEYYSqnkftpeQ--- 237 baker's yeast
WP_010889830 164 SLEVYYQTGIPISQFQKKQSSE-FKNIVI-IGLK-RSFEDLKTRISIRINEMLNSGLLSEIKGLFSKGY-------N--- 230 Lyme disease sp...
O25961       169 ALEIFYATCTPPSEYFKANPKKPFEHAISlFALS-IEKSALHNNIKRRTKNMLHSGLVEEIKALYTQYP-------K--- 237 Helicobacter py...

3FOZ_A       241 ----TDLPSIRCVGYRQMWSYLEG-----EISYDEMVYRGVCATRQLAKRQITWLRGWE------G------VHWLDSEK 299 Escherichia col...
P16384       241 ----TDLPSIRCVGYRQMWSYLEG-----EISYDEMVYRGVCATRQLAKRQITWLRGWE------G------VHWLDSEK 299 Escherichia col...
P44495       234 ----INLPSIRCVGYRQMWEYLQG-----DYAYEEMIFRGICATRQLAKRQLTWLRGWK------Tp-----IQWLDSLQ 293 Haemophilus inf...
O31795       236 -----DCQSIQAIGYKELYAYFDG-----FVTLSDAVEQLKQNSRRYAKRQLTWFRNKM------Q------VTWFDMTP 293 Bacillus subtil...
P74040       226 -----DLPLLHTLGYAEIKQYLQG-----QISLTQATESIIVHTRQFAKRQRTWFRKDS------A------IHWFDANQ 283 Synechocystis s...
P07884       246 tpeqCENGVWQVIGFKEFLPWLTGktddnTVKLEDCIERMKTRTRQYAKRQVKWIKKML------IpdikgdIYLLDATD 319 Saccharomyces c...
3EPH_A       238 ----CENGVWQVIGFKEFLPWLTGktddnTVKLEDCIERMKTRTRQYAKRQVKWIKKMLipdikgD------IYLLDATD 307 baker's yeast
WP_010889830 231 ----ENTPAFKGIGYNEFLLWKSRp----CYGLNDIIGLINKNSFLYAKRQMTFFAKIS------D------VLWLHPED 290 Lyme disease sp...
O25961       238 -----DSQPFKAIGVKESVLFLEK-----RLTLKELEEAITSNTMKLAKRQNTFNKTQF------N------NLYVGSAE 295 Helicobacter py...

3FOZ_A       300 P 300 Escherichia coli K-12
P16384       300 P 300 Escherichia coli K-12
P44495       294 P 294 Haemophilus influenzae Rd KW20
O31795       294 P 294 Bacillus subtilis subsp. subtilis str. 168
P74040       284 P 284 Synechocystis sp. PCC 6803 substr. Kazusa
P07884       320 L 320 Saccharomyces cerevisiae S288c
3EPH_A       308 L 308 baker's yeast
WP_010889830 291 D 291 Lyme disease spirochete
O25961       296 E 296 Helicobacter pylori 26695
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