1JSX


Conserved Protein Domain Family
rsmG_gidB
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TIGR00138: rsmG_gidB 
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16S rRNA (guanine(527)-N(7))-methyltransferase RsmG
RsmG was previously called GidB (glucose-inhibited division protein B). It is present and a single copy in nearly all complete eubacterial genomes. It is missing only from some obligate intracellular species of various lineages (Chlamydiae, Ehrlichia, Wolbachia, Anaplasma, Buchnera, etc.). RsmG shows a methytransferase fold in its the crystal structure, and acts as a 7-methylguanosine (m(7)G) methyltransferase, apparently specific to 16S rRNA. [Protein synthesis, tRNA and rRNA base modification]
Links
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Statistics
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PSSM-Id: 272928
Aligned: 21 rows
Threshold Bit Score: 163.58
Created: 7-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
1JSX_A        24 LIAYVNMLHKWNKAYNLTSVRDPN--EMLVRHILDSIVVAPYLQ-------G---E--R---FIDVGTGPGLPGIPLSIV 86  Escherichia coli
O67522        21 FSIYLQELLRWNKVHNLTSIKKPE--EIVRRHFIDSVSVVRCFErigldlrG---K--H---FADVGSGAGFPGVPLKIY 90  Aquifex aeolicu...
AAB53136      40 AQRYVDLLANTGIERGLLGPHEAN--RLWDRHLLNSAVVAELLDp------G---D--R---VVDIGSGAGLPGLPLAIA 103 Mycobacterium l...
Q9RYD6        32 FARLLALLRAGNERLNLTALKTEE--DIVLKHFVDSLTTLRGGHld----gE---W--K---TLDLGTGAGFPALPLAIL 97  Deinococcus rad...
P75220         6 LKQYVQLVQTANQNFNLTGLKTEG--EIYEHLVQEIIELFNEYDsyf------dhK--K---VADLGSGNGCPGVILKLL 72  Mycoplasma pneu...
WP_010966992  26 FMRYKELLQEWNKVMNLTSIVDDE--EIVKKHFIDSIKIFECEH-------IvkaK--R---IIDVGTGAGFPGLPIAIM 91  Clostridium ace...
WP_010873767  45 MVKLYQGVLVGNARLNLTRITAPL--DFLEKHLWDSLAGVLLSDhsr-ncpQ---A--R---VIDIGTGGGFPGLPVALV 113 Synechocystis s...
WP_011387639  24 LNLYYQILIEENQKYNLTRITELN--EVFEKHFLDSLLFVEQFQ-------I---IdqK---IADIGTGAGFPGIVLKIF 88  Mycoplasma capr...
WP_006689024  25 FEKYKTIIQKYNQIFNLTRLDSDD--KIYQNFFLDSLAPYKELDfft-qntN---L--K---LIDIGSGSGIPGVVLKII 93  Ureaplasma parvum
WP_006068528  24 INLYIKRILLLNTRFNLISNSNSNfnAILNLHVIDSLLGLSTIK-------E---I--NpseVLDVGSGAGFPGIVLAIF 91  Borrelia valais...

1JSX_A        87 RPEAH-FTLLDSLGKRVRFLRQVQHELKLENIEPVQSRVEE----F----PSEPPFDGVISRAFASLNDMVSWCHHLPGE 157 Escherichia coli
O67522        91 LKDIK-LTLIESVSKKCSFLEYLKIKLN-EDYRVLCTRAEK----------VEEKFDVVLARALGEFEEVKEILEKLS-- 156 Aquifex aeolicu...
AAB53136     104 RPDLQ-VVLLEPLLRRVTFLREVVAELGLD-VEVVRGRAEElw-vR----DRIGERDVAVSRAVAALDKLTKWSIPLLRP 176 Mycobacterium l...
Q9RYD6        98 RPELR-LTPLDSIRKKIDFVRETAAELGLSNVTPQVGRAETlgqsA----EHRGSYDRVVARAVAALPVLAELALPLLRV 172 Deinococcus rad...
P75220        73 FPQIKtLDLIDSKHKKVNFLKEVIQTLELNNTQALCARIEN----------HTEQYDTLCSRGLGSIIEVNAFALKLLKP 142 Mycoplasma pneu...
WP_010966992  92 NDDIE-VVLLDSLQKRVNFLNEVIKELNLKNISTVHGRAED----FgvdkDYREKFDVAVSRAVANMAVLSEFCLPFARV 166 Clostridium ace...
WP_010873767 114 WPQWS-VALLDSTHKKINYLEELGHRLGLANLAYLVARAEAvgnqP----QHRSQYDLALIRAVGEGVVCAEYALPLVKV 188 Synechocystis s...
WP_011387639  89 FPNIK-LTLIESNNKKVNFLKYLVQKLNLNDVEILNKRAEE----Ln---EYKEQFDIVISRAVAYLNIILELGVQLVKV 160 Mycoplasma capr...
WP_006689024  94 FKNLN-LTLLEANQKRCEFLKILTQELGLNDVLIWNMRAEDl--tQ----SMRESFDIATSRAVASLDKILEISAAFVKV 166 Ureaplasma parvum
WP_006068528  92 DTSRK-YYLLERSKKKSTFLKMIKLELDLENVKILEYEIE----------REKKKHEFITIRAFRSMNEYALILKNLLKD 160 Borrelia valais...

1JSX_A       158 QGRFYALKGQMPEDEIALLPEEyqvESVVKLQVPAL--DG-----ERH---LVVIK 203 Escherichia coli
O67522       157 IGYVFVYKGSKLKEEWLKDYKLcelSLSFMP--------------K-S---YILWK 194 Aquifex aeolicus VF5
AAB53136     177 GGQILAIKGEHVFDEIHQHRRVmasLGAVDVMVVVC--GAny--lCRP---VTVVL 225 Mycobacterium leprae
Q9RYD6       173 GGVFVAQKGPLSEEELDAGRRAageVGGRIIEVDPF--TLpvsgdART---LIVLE 223 Deinococcus radiodurans R1
P75220       143 NGII--FHIKQSLDQYLEFEDSeqkDQFKPLFFKFF--HGk---rQQI---LIAMK 188 Mycoplasma pneumoniae M129
WP_010966992 167 GGYLVALKGPGINDEISTAKKAikvLGGTLDKVINV--EFenedfQHN---LVVIK 217 Clostridium acetobutylicum
WP_010873767 189 GGTVVLYRGQWSAAEAEQLERAcalLGGKVSATVAA--VTpwsgaQRH---FIYLT 239 Synechocystis sp. PCC 6803
WP_011387639 161 NGMFILLKGPKAYQEIKDLKNKdqkMNLKLINIQELedTGf----GTR---INLFY 209 Mycoplasma capricolum
WP_006689024 167 NGYLIQPKSIKFYEEELKAKNIiktLYLERIALKDF--WEn----DYHhlvGVYLK 216 Ureaplasma parvum
WP_006068528 161 KGLIMAYKGKFDRINLEVGQIKdlfSKIEVKSLNPK--LSv----DRN---LVLLY 207 Borrelia valaisiana
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