Conserved Protein Domain Family
gatC

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TIGR00135: gatC 
aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit
Archaea, organelles, and many bacteria charge Gln-tRNA by first misacylating it with Glu and then amidating Glu to Gln. This small protein is part of the amidotransferase heterotrimer and appears to be important to the stability of the amidase subunit encode by gatA, but its function may not be required in every organism that expresses gatA and gatB. The seed alignment for this model does not include any eukaryotic sequence and is not guaranteed to find eukaryotic examples, although it does find some. Saccharomyces cerevisiae, which expresses the amidotransferase for mitochondrial protein translation, seems to lack a gatC ortholog. This model has been revised to remove the candidate sequence from Methanococcus jannaschii, now part of a related model. [Protein synthesis, tRNA aminoacylation]
Statistics
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PSSM-Id: 129241
View PSSM: TIGR00135
Aligned: 14 rows
Threshold Bit Score: 87.7386
Threshold Setting Gi: 6225423
Created: 7-Oct-2014
Updated: 2-Oct-2020
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q8Y3C2   3 LELSDVKRIAHLARIEVSDGEAAQTLTQLNQFFTLVEQMQAVdTTGIEPMAHPIEQVqapaQRLREDAVTEPDRRADYQQ 82  Ralstonia solanacearu...
O27956   2 VSIEDVYHTAELAKIEITEEQAEKFRKEFETILDYFNILDEV-EEDVEPTFHVLPLT----NVFREDEPGECLKQEEALS 76  Archaeoglobus fulgidu...
P58251   3 VSKKDVEYVAELARLSFSEEQKEGFMEDLNSILGYVDKLSELdTDNVDIIVNPYYIE----NKFREDEVEESMDLKDVIK 78  Clostridium acetobuty...
O53259   4 ISRDEVAHLARLARLALTETELDSFAGQLDAILTHVSQIQAVdVTGVQATDNPLKDV----NVTRPDETVPCLTQRQVLD 79  Mycobacterium tubercu...
Q9WY94   4 VTKDLVLHLENLARLELSEDQRESLMKDFQEILDYVELLNEVdVEGVEPMYTPVEDS----AKLRKGDPRFFEMRDLIKK 79  Thermotoga maritima MSB8
Q9RUV6   2 IDAAQIDHLTALARLELSPAERRTMQQDLTRMLGYFEQLGRVpTEGVQEMQRPVSLV----NVLRDDAPGETFPSGVVSA 77  Deinococcus radiodura...
Q92QK8   3 VDLATVKRVARLARIAVSDEEAERMTGELNGILGFVEQLSEVdVDGVEPMTSVMPMK----MKKRDDIVADGDKADDIVA 78  Sinorhizobium melilot...
P58528   3 ITTEDILDCANLSRLALDEKTAQNYAGNLDKILAMMDILDGVnTDNIKPLANIHEAC----NELRADIANSDIGRDGFQA 78  Moraxella catarrhalis
Q971U4   5 VNNELISRLQNLALVELNDREKERIKRDIKNILDFFDQINKLdLSNVEPLFHPIST-----GKLRKDEIIKPLSRDEALS 79  Sulfolobus tokodaii s...
P47344 389 LIRKEMQQLAKTIRIDLSDKEVDALVEEFKEITKSFNKVTKIdTTNVQPMYAPFEFSp---TPLRKDKPVVDKHAKQLLN 465 Mycoplasma genitalium...
Q8Y3C2  83 CAPSTEAGLYLVPKVIE 99  Ralstonia solanacearum GMI1000
O27956  77 NAKHKEEGYFKGPRVVE 93  Archaeoglobus fulgidus DSM 4304
P58251  79 NAPKNLEEYIVVPKIID 95  Clostridium acetobutylicum ATCC 824
O53259  80 QAPDAVDGRFAVPQILG 96  Mycobacterium tuberculosis
Q9WY94  80 NFPEEKDGHIKVPGIHR 96  Thermotoga maritima MSB8
Q9RUV6  78 LAPETQDGFIRVPRTVD 94  Deinococcus radiodurans R1
Q92QK8  79 NAPNSDRNFFLVPKVVE 95  Sinorhizobium meliloti 1021
P58528  79 VAPMVQDGLYLVPQVIE 95  Moraxella catarrhalis
Q971U4  80 NVKRKEDGFIVGPATYG 96  Sulfolobus tokodaii str. 7
P47344 466 NCCEVKTGFVKV----- 477 Mycoplasma genitalium G37
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