Conserved Protein Domain Family
gatB
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TIGR00133: gatB 
aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit
The heterotrimer GatABC is responsible for transferring the NH2 group that converts Glu to Gln, or Asp to Asn after the Glu or Asp has been ligated to the tRNA for Gln or Asn, respectively. In Lactobacillus, GatABC is responsible only for tRNA(Gln). In the Archaea, GatABC is responsible only for tRNA(Asn), while GatDE is responsible for tRNA(Gln). In lineages that include Thermus, Chlamydia, or Acidithiobacillus, the GatABC complex catalyzes both. [Protein synthesis, tRNA aminoacylation]
Links
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Statistics
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PSSM-Id: 272926
Aligned: 9 rows
Threshold Bit Score: 653.706
Created: 7-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
P33893        25 PEYALKCGLEIHTQLN-TKNKLFSQSTNSATSlVDapNHHTSYYDIALPGTQPV-LNLEAILFAMKLSLALGSQvNS--I 100 Saccharomyces c...
O51316         1 MEYKLVIGLEIHVQLG-LKTKAFCGCKNEFGG-VP--NSRVCPICLGLPGSLPS-VNVELINSAILAGHATNSK-IRn-V 73  Borrelia burgdo...
Q57624         6 EDVKMKCGLEIHVQID-TKSKLFCNCSTNYLDaEP--NTNVCPVCLGLPGAKPLpPNKKAVEVAIMVAKMLGCKiVVdeD 82  Methanocaldococ...
O27341         1 ----MKCGLEIHVQLD-TRSKLFCRCPTDYQEaPP--NTNICPVCLNQPGAKPYpPNRSALEGALKIALMLDCRiNp-eI 72  Methanothermoba...
P47346         2 INFEAIIGIEVHVVLN-TASKMFSKAPNRVDNqKI--NHFIDPIDLGLPGTLPQ-VNELAVYKALLLADALKMKtVTn-K 76  Mycoplasma geni...
WP_010872929  32 TDYEAIIGLETHCQLN-TASKIFCNCSTDFDS-PP--NTNVCPVCLGYPGVLPV-LNEEVLAAAVKLGLAINGQ-IAp-Y 104 Synechocystis s...
WP_010879607  21 IMDDVVIGLEVHVQLNrLRTKLFCSCPLNYHQsPP--NTHVCPVCLGMPGAMPV-INKEAVKAAVKVAMALNAE-IQp-F 95  Archaeoglobus f...
WP_000982564   2 MPFEAVIGLEVHVQLN-TKTKIFCSCSTSFGEs-P--NSNTCPVCLGLPGALPV-LNKEVVKKAIQLGTAIEANiNq--Y 74  Helicobacter py...
WP_014574916   2 INFEAIIGIEVHVVLN-TATKMFSPAPNQAQNaTP--NQFINAIDLGLPGTMPQ-VNEQAVQKALILADALNMQrVQp-V 76  Mycoplasma pneu...

P33893       101 SQFDRKHYFYGDQPQGYQLTQHYRPFARGGKINLSKELDDide-saKEIGILQLQIEQDTGKSHYTETDk---dVITLVD 176 Saccharomyces c...
O51316        74 VKFDRKHYYYPDLPKGYQISQNDKPICEGGSLLIETPSGP------KKINIIRIHMEEDSGKSLHLLDSe----NQSYVD 143 Borrelia burgdo...
Q57624        83 IYFQRKHYDYPDLPSGYQRTS--TPIGVDG----EFMG----------IGIHEVHLEEDPG--QYNp-------SFGIVD 137 Methanocaldococ...
O27341        73 TYFMRKHYNYPDLPSGYQRTS--IPVGLEG----ELNG----------VRIREVHIEEDPG--QYKp-------DQGTVD 127 Methanothermoba...
P47346        77 LVFDRKHYFYQDLPKGFQITQQNYPFAKNGVVTINVDAIE------KPIYIDRFHLEEDTAK-QHFNHD------QILLD 143 Mycoplasma geni...
WP_010872929 105 SKFDRKQYFYPDLPKNYQISQFDLPIVEHGSLEIELVDKKtkeitrKTIGITRLHMEEDAGKLVHAGSDrlagsTHSLVD 184 Synechocystis s...
WP_010879607  96 TVFDRKNYFYPDLPKGFQISQYDRPLALGGYVTIELDGQE------KRIQLKRVHMEEDPGKLSYKGSItt--aKYSLID 167 Archaeoglobus f...
WP_000982564  75 SIFARKNYFYPDLPKAYQISQFEVPIVSDGKLEIDTKEGA------KIVRIERAHMEEDAGKNIHEGS-------YSLVD 141 Helicobacter py...
WP_014574916  77 LVFDRKHYFYQDLPKGFQITQQNFPIAQNGYVEIVENNKA------QRIIIERFHLEEDTAK-QHFVDG------QILLD 143 Mycoplasma pneu...

P33893       177 LNRSNVPLIELVTKPDFSDIKQVRAFIKKYQNLVRHLHISSGDLETGAMRVDVNLSIN--------EYARVELKNLPNTS 248 Saccharomyces c...
O51316       144 FNRSGAPLLEIVSAPDINSGDEAVAFLSSLREIFRYLDLSECNMENGSFRCDVNVNLIvkengvehKTPIAEIKNLNSFK 223 Borrelia burgdo...
Q57624       138 YNRSGTPLIEIVTKPDIKSPEEAREFLKQLMTLFRYLGCLRG---EGTMRADVNISIEym----gvQGNRVEVKNVNSIK 210 Methanocaldococ...
O27341       128 FNRSGIPLIEIVTEPDMTSPEEARNFLRELIRVLEYSGCARG---EGTMRADVNISLE--------GGKRVEIKNINSIK 196 Methanothermoba...
P47346       144 FNRCGAPLIEVVTLPVINTAKEAKAYLQKLRQILIVNNISNAKLEDGSMRSDCNVSVRlkg--qrqLGTKIEIKNINSLN 221 Mycoplasma geni...
WP_010872929 185 FNRTGVPLLEIVSEPDLRTGQEAAEYAQSLRQLVRYLGISDGNMQEGSLRCDVNISVRpvg--qkeFGTKVEIKNMNSFS 262 Synechocystis s...
WP_010879607 168 YNRSGAPLLEIVTEPVMNSPKEARLFLNKLRMILEYLEVFDGDL-EGAMRVDANISIR--------GSGRVEIKNISSFK 238 Archaeoglobus f...
WP_000982564 142 LNRACTPLLEIVSKPDMRNSEEAIAYLKKLHAIVRFIGISDANMQEGNFRCDANVSIRpkg--dekLYTRVEIKNLNSFR 219 Helicobacter py...
WP_014574916 144 FNRCGAPLIEVVTAPVIKSAKQSKAYLQKLRQILIVNNISNAKLEDGSMRSDCNVSVRlkg--qtaFGTKVEIKNINSLN 221 Mycoplasma pneu...

P33893       249 SIINAIKYEYQRQVELISVGd---TSSLMEPETRGWTGSSTVKLRSKETTIDYRYMPDPELPYINLAPDVISG-VRGLMP 324 Saccharomyces c...
O51316       224 SIKAAIEYEELRQQQEWIQFkktlNSCGKHTRGFDDRSGVTVIQRNKETVSDYRYFQEPDLPLIEIDDSYIDNiKNLKLI 303 Borrelia burgdo...
Q57624       211 GVYKVLKYELIRQKNIIKRG----GEVKRETRAFLESQMITKAMRSKETAEDYRYIPDPDIQPIVISEKWVKE-IEEKMP 285 Methanocaldococ...
O27341       197 GAYKALKFEMIRQKNLLKRG----VEVKQETRAFLESQMITVSMRLKEEAEDYRYIPDPDLPPMKFTDEVVEG-LRERIP 271 Methanothermoba...
P47346       222 NVEKAIDLEINRQVKALING----ETLSQATLSFDDKTNNNVFMRKKDNTIDYRYFIEPNIMTSNIDDLLLEKpVAFQLE 297 Mycoplasma geni...
WP_010872929 263 AIQKAIEYEIERQIKAIADG----EEIYQETRLWEEGSQRTISMRKKEGSSDYRYFPEPDLPPLEVSEQ-QKQtWFATLP 337 Synechocystis s...
WP_010879607 239 GVEKALSYEIMRQKNLLQRG----RSVVRETRHFDEARNITVSLRSKEEEQDYRYFPEPDLVP-VLTEEIVRE-VEGTLP 312 Archaeoglobus f...
WP_000982564 220 FIAKAIEYEIERQSAAWENGry-nEEVVQETRLFDTHKGITLSMRNKEESADYRYFKDPDLYPVFIDEKLLKE--AQKIN 296 Helicobacter py...
WP_014574916 222 NVEKAIDLEIARQVKALIKG----EPVQQVTLTYDDKTNTNVFMRKKDNSVDYRYFIEPNIMSSNIDELLQKPnKAFNLT 297 Mycoplasma pneu...

P33893       325 QLPDdIMRILMKKPYQLSLKDAKILTYNSNqndmynhealrsyYLDTFREFSKLAGERsn-aKLPTNWIIHEFLGDLNKL 403 Saccharomyces c...
O51316       304 ELPF-HARIRLKGQYGLSDFDVITLTADKH-------------LLKYFEEAVINSSDP----KKVANWILSEVLSVLNDK 365 Borrelia burgdo...
Q57624       286 ETPL-AKKKRFVEEYGIDEEDAKVLVSDLD-------------MAEMFEEVVKSLGVNkenvDLAVTWIRNELRRSLQYH 351 Methanocaldococ...
O27341       272 EAPH-LKVKRFMEEYGLREEDARVLTSELE-------------LADAFEEVAGSIDP-----EFAALWMRDELKRVLYYN 332 Methanothermoba...
P47346       298 QF------QKELIDSNVNPQLVQLVVDDAT-------------IFSAFQTINSVIKNP----QETIRWLCIELIGQLNKT 354 Mycoplasma geni...
WP_010872929 338 ELPS-AKRARYEQKLGLSAYDARVLTEDRD-------------VALYFEEAVNAGADP----KAVANWVTQDIAAYLNNN 399 Synechocystis s...
WP_010879607 313 EMPE-EKRERLKRQYGIGDNFAKVLILDVK-------------MADYFEEVAKLV-DP----KLAASWIVDVLRGELNYR 373 Archaeoglobus f...
WP_000982564 297 ELPS-AKKIRYMKDFNLKEDDANLLVSDPL-------------LAQYFESMLHLGVKA----KTSVTWLCVELLGRLKAE 358 Helicobacter py...
WP_014574916 298 EF------FTKLKEAGVNEQLNQLVVDDLT-------------LFNAYTKINSVINSP----QDTIRWLCIELMGQLNKL 354 Mycoplasma pneu...

P33893       404 QIPLAKAkeILPPPVFAQFLKLLHEEVISATSGKMLLFHILENfeqsncqdlsIPDFSKLIEKfeLHAINQVDPQELMDL 483 Saccharomyces c...
O51316       366 GISVLEF--NLLPSYITELVEFIVAGKISGKMAKRVFSEMMTR----------GVSASVVISE--NQLEQVSDKFVIKQI 431 Borrelia burgdo...
Q57624       352 KVDLYES--GVKAEHIVELIKLIKEGVISQKIAKEIVDLLVINr--------gKKMPKELVEE--LGLTVIRDEDALVKA 419 Methanocaldococ...
O27341       333 KISFAES--MITPGDIIELLAMIRKKEITSKAAKKIIEEMPLN----------KKGPREIATE--MGLIGIIDESEVIRA 398 Methanothermoba...
P47346       355 NSSLTAN--LIQ--DLITLIEMLKAAKVNQKQAKQLITLMIET----------KKDPKSLAKL--HNLEQITDPKELQKI 418 Mycoplasma geni...
WP_010872929 400 RLTISGL--ALKPSALAELIDLITKGTISGKIAKDILPELLEK----------GGSPQKIIEA--RGLVQISDPDELTAI 465 Synechocystis s...
WP_010879607 374 DWSFAKCweVFKPEEFAKLLKYFEEDRITEKGVVEVIRTKLDE----------GGEIDAIIQK--KGLFAIPKE-EIIKF 440 Archaeoglobus f...
WP_000982564 359 -ITLENC--GVSTHMLGALAKRIDEGKISGKSAKDVLDKLLEEq---------GGDVDALIEQ--MGLSQVNDTEAIVKV 424 Helicobacter py...
WP_014574916 355 QKPLKDK--TID--HLIILIQMVQKGTVNQKQAKQLIELMLDN----------GQDPQSLAKL--HNLEQITDEKQLTQI 418 Mycoplasma pneu...

P33893       484 CNDVIAQHTDDTFIRNlvtGKKKSSLKFLIGQGMRRSQGRIKANEFEKKFKEILN 538 Saccharomyces cerevisiae S288c
O51316       432 VLEVLDENPKSIELYK---KGKDHAIKFMMGQIMKKSSGKINPILANEILLESLS 483 Borrelia burgdorferi B31
Q57624       420 VEEAIKNNPKAVEDYL---NGKKEALNFLMGQVMRLTRGRADPKRVIELLKERLD 471 Methanocaldococcus jannaschii DSM 2661
O27341       399 VEQAIRENPGAVEDYH---AGKEAAINFLVGQVMRMTRGKAEPERTVELIKERI- 449 Methanothermobacter thermautotrophicus s...
P47346       419 IKKIFQENEKEILKNI---DRIERIQKLIIGQVMHKTNNRANPQQVFIIVENMLH 470 Mycoplasma genitalium G37
WP_010872929 466 IQAVIADHPKELEKFR---SGKGNMQGFFVGQVMKRTGGKADPKLTNQLIGKLLA 517 Synechocystis sp. PCC 6803
WP_010879607 441 CKEAIEENPKAVEDYL---SGKRQALNFLVGQVMKKTRGRADPADTAKLIEEMLS 492 Archaeoglobus fulgidus
WP_000982564 425 IEEVLKNNADKVLEYK---SGKDKLFGFFVGQAMKNLKG-ANPSVVNAILKEKLG 475 Helicobacter pylori
WP_014574916 419 IQQIFKENEGEILKNL---DRVERIQKLIIGQVMQRTHNRANPQQVFIIVEKLLH 470 Mycoplasma pneumoniae
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