2W3T,2EW5


Conserved Protein Domain Family
pept_deformyl
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TIGR00079: pept_deformyl 
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peptide deformylase
Peptide deformylase (EC 3.5.1.88), also called polypeptide deformylase, is a metalloenzyme that uses water to release formate from the N-terminal formyl-L-methionine of bacterial and chloroplast peptides. This enzyme should not be confused with formylmethionine deformylase (EC 3.5.1.31) which is active on free N-formyl methionine and has been reported from rat intestine. [Protein fate, Protein modification and repair]
Links
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Statistics
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PSSM-Id: 272895
Aligned: 10 rows
Threshold Bit Score: 189.903
Created: 7-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2W3T_A   2 VLQvlHI-PDERLRKVAKPVEEVNAEIQ-RIVDDMFETMYA----------EE--------GIGLAATQVDIHQRIIVID 61  Escherichia coli K-12
P94462   3 VKKvvTH-PAEVLETPAETVTVFDKKLK-KLLDDMYDTMLE----------MD--------GVGLAAPQIGILKRAAVVE 62  Bacillus subtilis sub...
P56419   3 LLEiiHY-PSKILRTISKEVVSFDSKLH-QQLDDMHETMIA----------SE--------GIGLAAIQVGLPLRMLIIN 62  Helicobacter pylori 2...
P73441  16 PLEl-HYlGDKVLRQPAKRIAKVDDSIR-KLAKEMLQTMYS----------AN--------GIGLAAPQVGINKQLLVVD 75  Synechocystis sp. PCC...
O51092   1 MEMvfYP-NDLLRVKTKQIENIDDKIRD-YAKKMIELMDIS----------GG--------VGLAAPQVGLDLALFVVRE 60  Borrelia burgdorferi B31
P75527  28 PTK--AWlVLDDVKEINEPTKPVQFPLD-QASLDCIAKMMAyvdasyngdaEKygi---ipGIGIAANQIGYWKQMFYIH 101 Mycoplasma pneumoniae...
Q45495   4 MENivRD-GHPALRETAEPVELPPTDAEkQQLADMIEFVKNsqnp---elaEKykl---rpGVGLAAPQINIKKRMIAVH 76  Bacillus subtilis sub...
P44786   3 ALNvlIY-PDDHLKVVCEPVTKVNDAIR-KIVDDMFDTMYQ----------EK--------GIGLAAPQVDILQRIITID 62  Haemophilus influenza...
G64211  36 fqptktwlVFDDNALINKPTEAVNFPID-EQIETCIKKMIAyvda---sydGKaqeydiipGIGIAANQIGYWKQLFYIH 111 Mycoplasma genitalium
2EW5_A   2 LLEiiHY-PSKILRTISKEVVSFDAKLH-QQLDDMYETMIA----------SE--------GIGLAAIQVGLPLRMLIIN 61  Helicobacter pylori

2W3T_A  62 VSENr----dE-RLVLINPELLEkSGE-TGIe--EGCLSIPEQ-RALVPRAEKVKIRALDRD-GKPFELEADGLLAICIQ 131 Escherichia coli K-12
P94462  63 IGDD------RgRIDLVNPEILEkSGEqTGI---EGCLSFPNV-YGDVTRADYVKVRAFNRQ-GKPFILEARGFLARAVQ 131 Bacillus subtilis sub...
P56419  63 LPQEdgvqhkEdCLEIINPKFIE-TGGsMMYr--EGCLSVPGF-YEEVERFEKVKIEYQNRF-AEVKVLEASELLAVAIQ 137 Helicobacter pylori 2...
P73441  76 CEQDkp---dEpPLIMINPQITRtSEElCVVe--EGCLSVPNV-YMDVTRPRAIEVTYKDEH-GRPQKRLFAELTARVIQ 148 Synechocystis sp. PCC...
O51092  61 NKMA------RpLVFINPSIIETsYEFsSYKe--GCLSIPGVY-YDLMRPKAVVINFHDENG-KSFTIENSDFLARIIQH 130 Borrelia burgdorferi B31
P75527 102 LMDGg----vEhKCLLINPKIINlSANkSFLksgEGCLSVPKMhQGYVIRHEWITITGFDWLqQKEITITATGLFGMCLQ 177 Mycoplasma pneumoniae...
Q45495  77 AEDAsg---kLySYALFNPKIVShSVEkSYLtsgEGCLSVDEAiPGYVPRYARIRVKGTTLE-GENIDIRLKGFPAIVFQ 152 Bacillus subtilis sub...
P44786  63 VEGDk-----QnQFVLINPEILA-SEGeTGIe--EGCLSIPGF-RALVPRKEKVTVRALDRD-GKEFTLDADGLLAICIQ 132 Haemophilus influenza...
G64211 112 LNDLn----kEkKCLLINPKIIDqSENkAFLesgEGCLSVKKQhKGYVIRSEWITIKGYDWFeKKEITIKATGLFGMCLQ 187 Mycoplasma genitalium
2EW5_A  62 LPQEdgvqhkEdCLEIINPKFIE-TGGsMMYk--EGCLSVPGF-YEEVERFEKVKIEYQNRF-AEVKVLEASELLAVAIQ 136 Helicobacter pylori

2W3T_A 132 HEMDHLVGKLFMDYLS-PLK-QQRIRQKVEK 160 Escherichia coli K-12
P94462 132 HEMDHLDGVLFTSKIS-KYY-TEDELADMEG 160 Bacillus subtilis subsp. subtilis str. 168
P56419 138 HEIDHLNGVLFVDKLS-ILK-RKKFEKELKE 166 Helicobacter pylori 26695
P73441 149 HEMDHLNGVMFVDRVDnPLAlAESLKKEGFS 179 Synechocystis sp. PCC 6803 substr. Kazusa
O51092 131 EMDHLNGVLFIDYYEEkLKN--KLLKPYMRE 159 Borrelia burgdorferi B31
P75527 178 HEFDHLQGRFYYHRIN-PLN-PLFTNKEWKV 206 Mycoplasma pneumoniae M129
Q45495 153 HEIDHLNGVMFYDHID-KEN-PFKEPENAIA 181 Bacillus subtilis subsp. subtilis str. 168
P44786 133 HEIDHLNGILFVDYLS-PLK-RQRIKEKLIK 161 Haemophilus influenzae Rd KW20
G64211 188 HEFDHLQGRFFYQRIN-PLN-PWFKKPEWKV 216 Mycoplasma genitalium
2EW5_A 137 HEIDHLNGVLFVDKLS-ILK-RKKFEKELKE 165 Helicobacter pylori
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