2OT2


Conserved Protein Domain Family
hypC_hupF

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TIGR00074: hypC_hupF 
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hydrogenase assembly chaperone HypC/HupF
This protein is suggested by act as a chaperone for a hydrogenase large subunit, holding the precursor form before metallocenter nickel incorporation. [SS 12/31/03] More recently proposed additional function is to shuttle the iron atom that has been liganded at the HypC/HypD complex to the precursor of the large hydrogenase (HycE) subunit. . Added metallochaperone and protein mod GO terms. [Protein fate, Protein folding and stabilization, Protein fate, Protein modification and repair]
Statistics
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PSSM-Id: 129184
View PSSM: TIGR00074
Aligned: 10 rows
Threshold Bit Score: 91.2782
Threshold Setting Gi: 585286
Created: 7-Oct-2014
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2OT2_A         1 MCIGVPGQIRTID--GNQ------AKVDVCGIQRDVDLTLV--GscdengQ-PRVGQWVLVHVGFAMSVINEAEARDTLD 69  Escherichia col...
P24191         1 MCIGVPGQIRTID--GNQ------AKVDVCGIQRDVDLTLVgsCde--ngQ-PRVGQWVLVHVGFAMSVINEAEARDTLD 69  Escherichia coli
P74095         1 MCLALPGQVVSLM--PNSdpllltGKVSFGGIIKTISLAYVp--------E-VKVGDYVIVHVGFAISIVDEEAAQETLI 69  Synechocystis s...
Q57653         1 MCLAIPCKVVEII--EEDge--kyAIAEYKGVKQKAKLTLLd-------kE-VKIGDYILIHTGYALEVLSEEDAKLSLE 68  Methanocaldococ...
Q43955         1 MCIGIPLQVLECA--PGR------ALCGDDREARWIDTRLIe--------P-PAPGDWLLVFLGAAREALDAERAAQIRD 63  Azotobacter chr...
P27651         1 MCIGIPMRVVVGS--EFI------AQCERHGAISSISLMLVg--------P-QAPGTHLLTHLGSAIRVLDADEARAIDD 63  Rhizobium legum...
P37185         1 MCIGVPGQVLAVG--EDIhq---lAQVEVCGIKRDVNIALI--Ceg--npA-DLLGQWVLVHVGFAMSIIDEDEAKATLD 70  Escherichia coli
WP_010878866   1 MCIAIPGRIERID--YPI------AIVDFKGLKKEVRIDLL--E------N-PQIGDYVLVHVGMAIQKVDEEEAKKTWE 63  Archaeoglobus f...
WP_000335443   1 MCLAIPSKVIAIK--DNV------VLLETLGVQREASLDLM--G------EsVKVGDYVLLHIGYVMSKIDEKEALESIE 64  Helicobacter py...
WP_010877257   1 MCIAAPAQIIEIDseDNI------ATVDFGGVRQQVKLDLV--D------D-VEEGKYVLVHSGYAIEVMSDEAARESLE 65  Methanothermoba...
2OT2_A        70 ALQNMfDVEPDVG 82  Escherichia coli K-12
P24191        70 ALQNMfDVEPDVG 82  Escherichia coli
P74095        70 DLAEMgV------ 76  Synechocystis sp. PCC 6803 substr. Kazusa
Q57653        69 AWEELfKALEEME 81  Methanocaldococcus jannaschii DSM 2661
Q43955        64 ALCAL-QAVQAGD 75  Azotobacter chroococcum (strain mcd 1)
P27651        64 ALAGLaEAVEGra 76  Rhizobium leguminosarum bv. viciae
P37185        71 ALRQM-DYDITSA 82  Escherichia coli
WP_010878866  64 LLER--VADETGN 74  Archaeoglobus fulgidus
WP_000335443  65 LYQEMiARMNETQ 77  Helicobacter pylori
WP_010877257  66 AWDELlKALEEED 78  Methanothermobacter thermautotrophicus
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