1H3D,1USY


Conserved Protein Domain Family
hisG
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TIGR00070: hisG 
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ATP phosphoribosyltransferase
Members of this family from B. subtilis, Aquifex aeolicus, and Synechocystis PCC6803 (and related taxa) lack the C-terminal third of the sequence. The sole homolog from Archaeoglobus fulgidus lacks the N-terminal 50 residues (as reported) and is otherwise atypical of the rest of the family. This model excludes the C-terminal extension. [Amino acid biosynthesis, Histidine family]
Links
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Statistics
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PSSM-Id: 272888
Aligned: 38 rows
Threshold Bit Score: 179.279
Created: 7-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
1H3D_A         7 LRIAMQ-KsGRLSDDSRELLARCGIKINLHTQ-R-LIAM-AEN--M-P-I-DILRVRDDDIPGLVMDGVVDLGIIGENVL 77  Escherichia col...
WP_010870716   2 IMFALPnK-GRISEPVMKVLEKAGLKITVK-G-RsLFAN-TVD--D-N-I-KVMFARARDIPEFVADGVADIGVTGYDLV 72  Methanocaldococ...
WP_011554233   3 LKIALPnK-GRLSDEVRELFNDAGLEVRARGE-RaLTAS-L-G--G-E-F-EAIFVRAQDIPEFVADGAAHAGVTGWDLV 73  Myxococcus xanthus
WP_012545705   6 LKLGLP-K-GSLQETTLKLFKKAGYNIHVSH--RsYYPV-IDD--E-E-I-SGMLLRAQEVPVYVEKGYLDCGLTGYDWI 75  Thermodesulfovi...
WP_011610417   7 LRIALPsK-GALAKGTMNLLSACGLGVSRPNE-RqYFGS-IPA--L-PqV-KVLFQRAADIFTKVEEGSVDLGITGYDVV 79  Trichodesmium e...
WP_011449017   2 INIALP-K-GSLEEQTLQLFKEADLEVRRTD--RdYNPQ-IND--A-R-IgKVKILRPQEIPTYIEMGYFDMGISGLDWI 72  Methanospirillu...
WP_012642034   5 LRIAIAsK-GEYEQATLRFLESAGLSVWRPNP-RqYVGRlAGF--E-D-V-EILFQRTADIVQQVASGGADFGITGYDLV 77  Thermomicrobium...
WP_011281740   6 INIGIPsK-GRLRADILKIFKKNKLNLVSERGeRdLLGS-IKN--LnN-V-KVLYLHAREIVERLGDGSLDLGFSGFDLL 79  Candidatus Pela...
WP_011570117   3 VKLGVPsK-GRLMEKTFDWFGQHGVTLSRAGs-DrEYAG-AVDgiE-G-V-ALILLSAGEMPRELAAGRIHFGVTGTDLV 76  Roseobacter den...
WP_003597715   6 LVLAVPsK-GRLQENASAFFSRAGLKLVQKAGaReYRGT-LAGl-P-G-V-EVRYLSASEIAGQLASGAAHLGVTGEDLI 79  Methylobacteriu...

1H3D_A        78 EEellnrraqgeDPR----YFTLRR-L-----DFGGC-----RLSLATPVDE-AWDGPLSLN------------GK--RI 127 Escherichia col...
WP_010870716  73 LEr---------NVEd--kVDFLLD-F-----GFGFA-----KLVLAAPESS-NINSIDDIKe-----------GM--RV 116 Methanocaldococ...
WP_011554233  74 CEs---------GRE----LDLLMD-L-----EFGRC-----RLVVAAREEG-GFASPEDVKe-----------GM--RV 115 Myxococcus xanthus
WP_012545705  76 LEq---------NVD----VIEVAE-LryakeGFRPV-----KWVIAVPEDS-PIKTVEDLQ------------GK--RI 121 Thermodesulfovi...
WP_011610417  80 CEe---------GQShddvIVIWDK-L-----GYGKC-----KLVLAVPESWvDVSSIEDLAeltll---frdkGKnlRI 136 Trichodesmium e...
WP_011449017  73 HEs---------GAQ----VKEVAQ-L-----NYSKTgpgivKIVVAVHQSE-PISTVSEIRp-----------DS--RI 119 Methanospirillu...
WP_012642034  78 AEla------gdDPD----VLVVFDdL-----GFRRC-----QLVLAVPESWlDVTTLADLAdlavew-krrgrTM--RI 134 Thermomicrobium...
WP_011281740  80 KEs---------EVNiqkkISVVKN-Y-----GFGKA-----TLVVAIPDPWiDVQTVADLEeiafe--fkdkkKKrlRV 137 Candidatus Pela...
WP_011570117  77 QEklp-----lwDQM----VEPVRE-L-----GFGFA-----DLVLAVPQAWvDVDTLDDLDavata--frhthGMrlRI 134 Roseobacter den...
WP_003597715  80 REmlp-----dpGAS----VELLTP-L-----GFGHA-----SVVVAVPQAWiDVRAMSDLDevasemrlrqgrRM--RI 137 Methylobacteriu...

1H3D_A       128 ATSYPHLLKRYLDQKG-I-S-FKSCLLNGSVEVAPRAGLADAICDLVSTGATLEANGLREVE--V--IYRSKACLIQ 197 Escherichia coli B...
WP_010870716 117 ATEFPNLTKKYFEKLN-K-K-VEIIELSGATEIAPFIGIADLISDLTSTGTTLRLNRLKVID--E--IVSSTTRLIA 186 Methanocaldococcus...
WP_011554233 116 ASCFPRLTQEFFARRG-Q-R-VAVVPVSGAAEIAPHLGIADIVVDLTSTGSTLKMNGLREVG--T--VLESSARLVA 185 Myxococcus xanthus
WP_012545705 122 ATELVGYTKRYLKSKG-I-K-AEVYFSWGATEVKPPY-LADAIVDLTETGTSLKANKLRVIE--T--ILESTTRFIT 190 Thermodesulfovibrio
WP_011610417 137 ATKYHHLTQKWLYEKL-IvH-FSLVAVQGAMEAAPSMGYADMIADITSTGTTLRENRLKQIEggT--LIESQACLIG 209 Trichodesmium eryt...
WP_011449017 120 TTEYPKLTKEFFEKLN-I-P-VRLFPSYGASE-AKVPDLMDVVVDLTETGTTLRKNGLKIIG--Q--IMESYTTIIA 188 Methanospirillum h...
WP_012642034 135 ATKFPNLTREFLLRNG-V-NyFTLVEGHGALEIAPALGYADLIADLTETGVTLRENRLRVLEggV--ILRAQACLIA 207 Thermomicrobium ro...
WP_011281740 138 ATKYPNLTREFLFSKGvT-Q-FKLVSSLGATEAYPFTGSSEIITDITSSGETLRANNLRILKdgE--ILKSEACMMA 210 Candidatus Pelagib...
WP_011570117 135 ATKYHRLVREYLRQGGvA-D-YALVDSQGATEGTVANETAEAIADITSSGETLRANHLKILS--DgpVLRSQATLWR 207 Roseobacter denitr...
WP_003597715 138 ATKYVNLTRRFFAEAG-IaD-YRIVESLGATEGAPAAGSAEIIVDITTTGTTLAANALKILDdgV--MLRSEANLVA 210 Methylobacterium e...
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