4CND


Conserved Protein Domain Family
rRNA_methyl_1
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TIGR00050: rRNA_methyl_1 
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RNA methyltransferase, TrmH family, group 1
This is part of the trmH (spoU) family of S-adenosyl-L-methionine (AdoMet)-dependent methyltransferases, and is now characterized, in E. coli, as a tRNA:Cm32/Um32 methyltransferase. It may be named TrMet(Xm32), or TrmJ, according to the nomenclature style chosen [Protein synthesis, tRNA and rRNA base modification]
Links
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Statistics
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PSSM-Id: 272876
Aligned: 8 rows
Threshold Bit Score: 293.922
Created: 7-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
4CND_A        19 QNIRIVLVETSHTGNMGSVARAMKTMGLTNLWLVNPLVK-PDSQAIALAAGASDVIGNAHIVDTLDEALA--GCSLVVGT 95  Escherichia col...
P37005         1 MRITIILVAPARAENIGAAARAMKTMGFSDLRIVDSQAH-LEPATRWVAHGSGDIIDNIKVFPTLAESLH--DVDFTVAT 77  Escherichia col...
P77438         3 QNIRIVLVETSHTGNMGSVARAMKTMGLTNLWLVNPLVK-PDSQAIALAAGASDVIGNAHIVDTLDEALA--GCSLVVGT 79  Escherichia coli
WP_010868980   3 ENIRIVLIETSHSGNIGSAARAMKTMGLTQLCLVSPKS--VDEQSYALSAGAENIVKNARVVDSFDEAVD--DCPLVIGT 78  Haemophilus inf...
BAM53746       2 ENIAIVVVEPQGERNVGAIARAMKNMGLEELILVNPRCDyRSVEAQTMAVHAKDVLAQAKVVDDLATALG--DRQRIIAT 79  Bacillus subtil...
WP_010877451   9 ENISVVFVEPETPGNIGFLARAMKNFGLRTLILINPCE--LEDEAYYQAMHARDIVEGALIYRDLSEMIDslEPDFLVGT 86  Methanothermoba...
AIG98801       1 mevwpVLVELKIPENVGFIARVAKNYGIKRLCLYKCRV---TEESYHTAANAKDVLENAVVVEDLQEFLQ--RMNLIVGT 75  Archaeoglobus f...
WP_010870997   3 IMISVILVNPKYSGNVGSIARVMMNFGFEELRIVGDKSi-INNEAYMMAVHAREILDNAKFYNTFDEAIG--DLDFVIAT 79  Methanocaldococ...

4CND_A        96 S-AR---SRTLPWPMLDPRECGLKSVAEAAn-tPVALVFGRERVGLTNEELQKCHYHVAIAANPEYSSLNLAMAVQVIAY 170 Escherichia col...
P37005        78 T-AR---SRAKYHYYATPVELVPLLEEKSSwmsHAALVFGREDSGLTNEELALADVLTGVPMVADYPSLNLGQAVMVYCY 153 Escherichia col...
P77438        80 S-AR---SRTLPWPMLDPRECGLKSVAEAAn-tPVALVFGRERVGLTNEELQKCHYHVAIAANPEYSSLNLAMAVQVIAY 154 Escherichia coli
WP_010868980  79 S-AR---LRHLQNTLIEPRECAEKVVAYKG---KIAIVFGRERIGLTNEELLKCHYHLNIPANPDYSSLNLAMAVQLVSY 151 Haemophilus inf...
BAM53746      80 S-AR---ERILQSPMETPRQALPWLLAPNL---KSALVFGREDSGLTNEELNQAHRFVRIPVHPQYPSLNLSQAVMVCTY 152 Bacillus subtil...
WP_010877451  87 TgVPg-gSYNVDRIPLRPSQLADAIRPSSG----TFILFGREGDGLSNEEIGLCDMVVSVPTSEEYPIMNITHAAAIIFY 161 Methanothermoba...
AIG98801      76 TgIPggdYKYLRKELLAPEDLPSVA---KG---RVAVLFGREDYGLYNEELEMCHVLVRVPTSEEYPVMNVSHAAAVILY 149 Archaeoglobus f...
WP_010870997  80 SgARg-gDRNLKRVPITPKELADKILEVKG---NIGIVFGREDDGLRNEEIDKCDLLVSIPTSEKYPIMNLSHAVAVILY 155 Methanocaldococ...

4CND_A       171 EVrmAWLATQENgeqveH----------EEt--PYPLVDDLERFYGHLEQTLLATGFIREnhpgqvMNKLRRLFTRARP- 237 Escherichia col...
P37005       154 QL--ATLIQQPA-----K----------SD---ATADQHQLQALRERAMTLLTTLAVADD------IKLVDWLQQRLGLl 207 Escherichia col...
P77438       155 EVrmAWLATQENge--qV----------EHeetPYPLVDDLERFYGHLEQTLLATGFIREnhpgqvMNKLRRLFTRARP- 221 Escherichia coli
WP_010868980 152 ELrmAFLVQNNKknslsL----------IEk--NYPTTDQLAYFFDYTERIYQSLGFIQNqg---vMRKLKRLYYRAKL- 215 Haemophilus inf...
BAM53746     153 ELyqASLAMETN-----NqvpgdrledgSTm--PLATNAQLDSYCQHLEKTLLNIEVLYPhtarskMAKFRRIYQRAAL- 224 Bacillus subtil...
WP_010877451 162 ELfrDREFRCEG-----L---------------EEASALEKSLLLEEMDDIL-SLIDIPEhkqrvaSRVFRNITGRAFI- 219 Methanothermoba...
AIG98801     150 FLreIERVQEDD---------------------EIATFRDIEVTLSNLVEML-RMVQYPEhrikrtVVIFRRILGRAGV- 206 Archaeoglobus f...
WP_010870997 156 EIytKKVRNKFL-----D----------INm--REASKEDKELLIRKFNEFIDKNEKIPEhkkelcKIIFKRLVNRAFIs 218 Methanocaldococ...

4CND_A       238 ESQELNILRGILASIEQqnK 257 Escherichia coli K-12
P37005       208 EQRDTAMLHRLLHDIEK--N 225 Escherichia coli K-12
P77438       222 ESQELNILRGILASIEQqnK 241 Escherichia coli
WP_010868980 216 EKNELNILNGMLSAVEKriD 235 Haemophilus influenzae
BAM53746     225 NSEEVALLRGILGQIDWlaQ 244 Bacillus subtilis BEST7613
WP_010877451 220 TAREAHTLKGVLRRIKNrmK 239 Methanothermobacter thermautotrophicus
AIG98801     207 KKYEVHSLNAIFRKTVSyiK 226 Archaeoglobus fulgidus DSM 8774
WP_010870997 219 GKEAWTLMSAFK-------- 230 Methanocaldococcus jannaschii
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