1I8T


Conserved Protein Domain Family
UDP-GALP_mutase
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TIGR00031: UDP-GALP_mutase 
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UDP-galactopyranose mutase
This enzyme is involved in the conversion of UDP-GALP into UDP-GALF through a 2-keto intermediate. It contains FAD as a cofactor. The gene is known as glf, ceoA, and rfbD. It is known experimentally in E. coli, Mycobacterium tuberculosis, and Klebsiella pneumoniae. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]
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Statistics
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PSSM-Id: 272864
Aligned: 5 rows
Threshold Bit Score: 567.489
Created: 7-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
1I8T_A         1 MYDYIIVGSGLFGAVCAN-ELKKLNKKVLVIEKRNHIGGNAYTEDCEg--IQIHKYGAHIFHTNDKYIWDYVNDLVEFNR 77  Escherichia col...
P37747         1 MYDYIIVGSGLFGAVCAN-ELKKLNKKVLVIEKRNHIGGNAYTEDCEg--IQIHKYGAHIFHTNDKYIWDYVNDLVEFNR 77  Escherichia col...
Q49398        20 SFDILIVGAGISGIVLAN-ILANHNKRVLIVEKRDHIGGNCYDKVDSktqLLFHQYGPHIFHTNNQTVINFISPFFELNN 98  Mycoplasma geni...
WP_010875983   1 MFKYIIVGAGLAGSVMAErIASQLGERVLVVERRRHVGGNCYDEVDDn-gILVHRYGPHILHTDSEEVFHYLSGFSEWRE 79  Methanothermoba...
P75499        14 KFDFIVLGAGISGIVLSH-VLAQHGKSVLLLEKRNQLGGNCYDKLDEttgLLFHQYGPHIFHTDNQKVMDFIQPFFELNN 92  Mycoplasma pneu...

1I8T_A        78 FTNSP-LAIYKDKLFNLPFNMNTFHQMWGVKDPQEAQNIINAQkKK-YGDKVP-ENLEEQA---ISLVGEDLYQALIKGY 151 Escherichia col...
P37747        78 FTNSP-LAIYKDKLFNLPFNMNTFHQMWGVKDPQEAQNIINAQ-KKkYGDKVP-ENLEEQA---ISLVGEDLYQALIKGY 151 Escherichia col...
Q49398        99 YHHRVgLKLKNNLDLTLPFDFQQIYKLMG-KDGRKLVSFFKEN-FS-LNTHLSlAELQLIDnplAQKLYQFLISNVYKPY 175 Mycoplasma geni...
WP_010875983  80 YQHRV-LGFIDGAKVPLPFNLNSLRMLLPQSLAERLEEKLVGR-YG-FGARVPiLELRESGdpdIEFLADYVYRKVFLNY 156 Methanothermoba...
P75499        93 YQHRVgLQLDNNLDLTLPFDFSQMRKLLDTKTASSLINFFQQH-FP-AEKHLTlMQLQTINfapVQQLYQFLKIKVYGPY 170 Mycoplasma pneu...

1I8T_A       152 TEKQWGRSAKELPAFIIKRIPVRFTFDNNYFSDR-YQGIPVGGYTKLIEKMLEG--VDVKLG---IDFLKDKDS---LAS 222 Escherichia col...
P37747       152 TEKQWGRSAKELPAFIIKRIPVRFTFDNNYFSDR-YQGIPVGGYTKLIEKMLEG--VDVKLG---IDFLKDKDS---LAS 222 Escherichia col...
Q49398       176 SVKMWGLPFAMINENVINRVKIVLSEQSSYFPDAiIQGLPKSGYTNSFLKMLANplIDVQLNc-kDNLLVYQDEklfFNN 254 Mycoplasma geni...
WP_010875983 157 TRKQWGLKPEEMDPEVTGRVPVVLSRDDRYFTDR-YQAVPRDGYTAMVERMLDHpcIKLMLNtshHEVLELRDGqihFMG 235 Methanothermoba...
P75499       171 SVKMWGMPLEQIDPSVLGRVKISLSENSSYFPTAtIQGLPKGGYTKAFTKMVDHplIDLRLNc-pANLISVNNNqllFAN 249 Mycoplasma pneu...

1I8T_A       223 KAHR--IIYTGPIDQYFDYRFGALEYRSLKFETERHEFPNFQGNAVINFTdANVPYTRIIEHKHFDYVE--TKHTVVTKE 298 Escherichia col...
P37747       223 KAHR--IIYTGPIDQYFDYRFGALEYRSLKFETERHEFPNFQGNAVINFTdANVPYTRIIEHKHFDYVE--TKHTVVTKE 298 Escherichia col...
Q49398       255 NLIEkpVVYCGLIDKLFNFCFGHLQYRSLAFSWKRFNQKKYQTYPVVNMP-LAKSITRSVEYKQLTNQGsfKPQTIVSFE 333 Mycoplasma geni...
WP_010875983 236 SEFRgkVIFTGKIDELFGYRYGELPYRSLDLQFESADTEWFQEVATVNYP-NDYDFTRITEFKHLHPTD--SRRTTLLRE 312 Methanothermoba...
P75499       250 QPITkpVVYCGLIDQLFGYCFGRLQYRSLHFEWKRYAVKQHQAYPVMNWP-LHPTITRQVEYKQLTQEGleSNQTIVSCE 328 Mycoplasma pneu...

1I8T_A       299 YPLEWKVGD----EPYYPVNDNKNMELFKKYRELASREDKVIFGGRLAEYKYYDMHQVISAALYQVKNIMS 365 Escherichia coli K-12
P37747       299 YPLEWKVGD----EPYYPVNDNKNMELFKKYRELASREDKVIFGGRLAEYKYYDMHQVISAALYQVKNIMS 365 Escherichia coli K-12
Q49398       334 TPGSYAINDprfnEPYYPINNTLNDTLFKKYWKKASKLKNLHLLGRLATYQYIDMDKAILLSIKKAQQLLS 404 Mycoplasma genitalium G37
WP_010875983 313 YPCTHIDGEn---EACYPVFTDETRAKYERYLELAREFEDLILVGRLAEYRYYDMDDIVLRALQVFEERIL 380 Methanothermobacter ther...
P75499       329 TPGAFREGDprfmEPYYPLNDVSNNALFARYLKLANAIPNIHLLGRLALYQYIDMDRAIAQSLAKAEQLLQ 399 Mycoplasma pneumoniae M129
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