Conserved Protein Domain Family
PRK14973

?
PRK14973: PRK14973 
DNA topoisomerase I; Provisional
Statistics
?
PSSM-Id: 184936
Aligned: 5 rows
Threshold Bit Score: 1748.96
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
?
Aligned Rows:
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
219851924   1 MHLIITEKNIAADRIAHILAGKTYVEVKKDGGVSTYSFNDTVVVGLRGHVVEVDFEPGYTNWRSEVNTPRSLISARTIKA 80  
124485959   1 MHLIIAEKNIVAERIAAFLAGKAKVQVTRDGAAAHYVFDDTVVMGLRGHVVEVDFVEGYNNWRSVEHPPRSLINADIVKK 80  
88602302    1 MHLIIAEKNIAANRIAQILSGKDKVSAKKEGGVNVYTFGDKISIGLRGHVVEVDFVEGYTNWRSQERPPRSLIDAETIKR 80  
154150402   1 MHLIVAEKNISAHRIAQILAGGTRVIEKKDAGVSTYSFGDTITVGLRGHVVEVDFEPGYENWRSEKYTPRSLIDAKTIKV 80  
126178720   1 MHLIIAEKNISANRIAQILAGNEKVRATKDGSVSTYSFDTKTVVGLKGHVVEVDFEPGYTNWRSETHTPRTLIDAGIVKK 80  
219851924  81 PTDKKIVTLIQKLTKKADHVTIATDFDTEGELIGKETYDLVKAVKPDVRVDRSRFSAITEEEIQTAFAAPAELDFALAAA 160 
124485959  81 PTEKKIVGLMQKFGKKATRVTIATDYDTEGELIGKEAFELIRAANPKVPIDRARFSAITKDEIVKSIKEATSLDFNLASA 160 
88602302   81 PTEPAIVKLIHKIAKKANRVTIATDFDTEGELIGKEAYELVRAVNPKVPIDRARFSAITKEEINRAFSEPSDLDFDLAAA 160 
154150402  81 PTEKRIVSLVQKLARHADRVTIATDFDTEGELIGKEAYELVRAVNKNVKIDRARFSAITAQEIGSAFANTTDLDFALAAA 160 
126178720  81 PTEKKIVNLIQKLSRKADLVTIATDYDTEGELIGKEAYELVRAVNPNVRINRARFSAITPAEIRTAFENLTDLDFDLAAA 160 
219851924 161 GEARQLIDLIWGASLTRFISLAAHRGGKNILSVGRVQSPTLAMMVDREKEIEAFVPEPYWVLTVDSNKDGEPVLARHTTA 240 
124485959 161 GESRQIIDLVWGASLTRFLSITAHRGADSILSVGRVQSPTLAMIVDREREIEAFVPTKYWMLSLATEKSGIGVEARHVHG 240 
88602302  161 GEARQVVDLIWGASLTRFISLAAKRGGGNILSVGRVQSPTLAMIVDREKEIESFIPEPYWEISLTTEKDGQSIIARHAEG 240 
154150402 161 GEARQSIDLMWGASLTRFISLAAKRGGNNILSVGRVQSPTLSMIVDREKEIEKFVPEKYWQLGLLTEKAGEQIEARHTNG 240 
126178720 161 GEARQTVDLMWGASLTRFISLAARRGGTNILSVGRVQSPTLAMIVEREREIESFVPQTYWMLSLATEKDGVTIEARHTAG 240 
219851924 241 RFTDVAIAEEAKEATRAPLMVTEVKEGSKVDRAPTPFDTTGFIVAAGRLGFSAANAMRIAEDLYMHGYISYPRTDNTIYP 320 
124485959 241 RFTDSAEAKAAYDATVEPLRVTDVITGHKVDRAPTPLDTTALIVGASRLGISASYAMNRAEDLYMRGFISYPRTDNTAYP 320 
88602302  241 RFTDKKLADAAYAGTKDPLVVTEVKEGKRVDRAPTPFDTTQFIVAAARIGYSAANAMRVAEELYMNGFISYPRTDNTIYP 320 
154150402 241 RFKDQKAAELARDRTKEPLVVTEVREGTKQDRSPSPFDTTTYIVAAARLGFSAANAMRIAEELYMNGYISYPRTDNTVYP 320 
126178720 241 RFTDHEAALAAEAGTKEPLVVTDVKEGQKNDRAPTPFDTTTFIVAASRLGLSAANAMRLAEDLYMNGYISYPRTDNTVYP 320 
219851924 321 RSLDLNGVLKTLQKTELSSAVIWVMANRRPVPTQGKKSTTDHPPIHPSGAATRAELGDE-RWKIYELVVRRFLATLSPDA 399 
124485959 321 KSLKISEQLAIFAHGAFSKEAGYVKDHLRSVPTRGKKETTDHPPIYPTSLANREEIGDDvSWKLYEFIVRRFFATICIDA 400 
88602302  321 PSLNLDNILTTLEKTKFARDVAWVRKNRRTKPTEGKKSSTDHPPIHPTGVATEEQLGEN--WKLYELVVRRFLATLSPDA 398 
154150402 321 ASLDLNGVLATIRNSPFTKDVDWIISHRRAEPTRGKKSSTDHPPIYPTGVATREGIGDD-AFRIYELVLRRFLATLAPDA 399 
126178720 321 KSLNLNAILNTLKGGVFDKDVAWVQQNRRPVPTRGKKESTDHPPIHPTGSATREALGQD-RWKVYELVVRRFLATLSPDA 399 
219851924 400 RWMTMKVLFTAGNEPYTTTGATLLEAGWRTVYPYSDATEHPLPRFAVGDSLPIEQVNLDRKETQPPPRYTQSRLIQQMEE 479 
124485959 401 EWETMKVNLLAGSEPYTITGGRILEAGWRGIYPYSKAEENLLPAFTLGETLPLLAKTSDEKETQPPARYSQSRLIQRMEE 480 
88602302  399 EWATMRIGMDATGQNYVATGSRLTEAGWRTVYPYSEAKDSILPVVKKGEKLKIQDLNLEEKQTQPPPRYSQSKLIQVMEE 478 
154150402 400 LWKTLKVNFEAGGETYTVTGGLLLEPGWHAVYPFSEAKETILPAFVTGEKLPIRKVNLEEKETLPPARYTQSKLIQRMEE 479 
126178720 400 NWATTRCTFDASGEAYKATGGRLLYAGWRRIYPYSEAKENILPVLAPGERLPIKNVNLEEKETQPPARYSQSRLIQVMEE 479 
219851924 480 LGLGTKSTRHEVIGKLVGRKYIEGNPLRPTLVGRAVIESLEDHAAAITRPDMTQTIDAHMQQIKERKRTRDDVVTESRAM 559 
124485959 481 LGLGTKSTRHEVISKLSGRKYIEGNPMKPTIVGRAVTESLEEFAGTITEPTMTKTLEEHMGDIAAGTKTINAVLSESRKM 560 
88602302  479 LGLGTKSTRHEVIQKLISRKYIEGNPLRPTLVGKAVTESLEAHASTITRPDMTQKLEQAMEAIKVRNKSRDGVVDDSRKM 558 
154150402 480 LGLGTKSTRHEVIARLVSRKYIEGNPLRPTLVGRVVTEALEQNADTITKPEMTQTIESHMQQIKESKRTRDDVIAESRSM 559 
126178720 480 LGLGTKSTRHEVIGKLVSRRYVEGNPLRPTLVGRAVIDALDNHAETITEPEMTQTLEEHMQLIKQSQRSRDDVVTESREM 559 
219851924 560 LNRAFDELEEHQSQIGEDIMGRTVEEMILGPCPVCGSDLRIHHIrNSSQFIGCTRYPDCRFNIGLPLTQWGWAIRTDTVC 639 
124485959 561 LTGIFDDLEKNEAAIGRDLMERTREEQTIGPCPVCGKPLRIKRV-GSSQFIGCSGYPDCTFNTGLPPATWGNAIKMDEVC 639 
88602302  559 LHQVFDELEPNEAVIGQEIMGQTDEELTIGPCPVCGKDLRIRRK-GGSQFIGCNGYPDCTCNISLPGTMWGSAVRTKKVC 637 
154150402 560 LHKAFDQLEANEQVIGNDIRDRTAEELNLGRCPACGGTLAIKHMrGSTQFIGCSRYPECTFNIGLPVTQWGWAVRTDDIC 639 
126178720 560 LHRVFDKLEAHKSEIGTEIMEQTAEEHTVGPCPDCGHDLRIRHI-GVSQFIGCTGYPECRFNISLPGSTWGKAIRVEATC 638 
219851924 640 PTHHLNHVRLIAKGSRPWDIGCPLCHHIESNQETMVLIPSMTEEILGRLQQHHIYTVHEVADAPPEALASAAEISSTAAE 719 
124485959 640 GIHGLNHVQLLRKGAPAWKIGCPLCSHIKSNTESFLLMPGMTAEGVQKLNAVHIYTLSELISRGPEELSKSLGLSKSEAE 719 
88602302  638 EVHNLFHVSLIAKGARPWEMGCPLCQLIEQQKEHYAKMPAMTEALQQKLLDAKIFSLYELSKLEPAVLAKKLGITKKQAE 717 
154150402 640 DKHHLHFVRLVRKGARPWDIGCPLCHHISSNAESLTEIPSMDEALLEKARSKHIYTVAEIARSEPDALAKSLDLPLEKAG 719 
126178720 639 PEHNLSHVRLIRKGARPWDIGCPLCSHITSNVEALRMMPSMTDDLMQRLHAQHIYTVSEIAGMQPEDLAKAVDVGTKEAV 718 
219851924 720 HLKSEGEAVLGLLRLRSELRKFVRKQVPPRRGRSHAKIMKHLHANGINTIADLAKADPTLLRTAGVGEKEVTSLLMQAKE 799 
124485959 720 KLIREAGSVLALLKKRTELKKFVSSHVAPKRGRGHSKVSAALISLGVVDVEALSRADPKDLLETKLSEAEAASLVAEAKS 799 
88602302  718 TLIHEANDVLDLIRRRSECKKFMKQFVPPKRGRSHTKVMNGFTESGINCIGDIASATIESLKKTGLSEEEAKTLKSEAIS 797 
154150402 720 KLKSEAGIVLEKLRRRSECRKFLRNHLIPRKGRSYAKIMEALGQSGVTDLASLAHATPATLQQAGIGETEARDLLTEARL 799 
126178720 719 ELAREAEDALEVLRRRSELRKFVRKIVPPRRGRSHAKIIKNLLGQGIGDIHALSVAEPAALKKAGIPEAAGAELLEAARG 798 
219851924 800 YCNDKTLRAIGVPAISLKKYYAAGIQSPEDFCRYHPVYLSVKTGISPDTTFRHAEMVCIAQNRPVPRKVTRAMLERGRAE 879 
124485959 800 MVNISRMKEYGVPAITLKKYVNAGFDDPEKFISVHPAGLSLATGVSVTTICNHQKLVAEKLCRPCPEKISKAAFEEGIAP 879 
88602302  798 LIAKNQLKDIGIPAVSLKRYQEAGFLTPEDIASAHPAYLAFKTGISIETVGKHATLITQSLGKPDPVKISKKAFESGKIE 877 
154150402 800 THNSQLLKGTGIPAVSLKKYLEAGVSGPEDFVSTGAEKLATLTGMSTGTINRHLALVCEYLHRPVPLAVPKAKLAKGRKE 879 
126178720 799 LCNERALREAGVPAVSLKKYQAGGVATLDDFCYLPIPYLASKTGINPETVHKHVDLVCRHLGRPAPQKISRTVFERGRKE 878 
219851924 880 LLtiPGLGETTIEKLYSGGVIDGMTLASADPAALASHSGIPLKKVQEFQSRLPGSSQA 937 
124485959 880 LR--KKAEPELLTPLALAGVYSPDLLVKADAKTLAKVTGIDEKQIVNLQKYAQKVLEK 935 
88602302  878 LTslPGVGESTLEHLYRAGIFDKKSLISADPAKVAKSGGLSKDHLKKLQAAAVV---- 931 
154150402 880 LLsvKGLAATTADKLIGAGVISGDLLLAADTKKLAASTGIDEEKLRGYQALMKKKKEN 937 
126178720 879 LLevPGLGEATVDRLYLAGIYDAATLRVADPEEVSSVTGIPKARLRDYIGHLK----- 931 
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap