Conserved Protein Domain Family
PRK13518

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PRK13518: PRK13518 
glutamate--cysteine ligase
Statistics
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PSSM-Id: 184108
Aligned: 12 rows
Threshold Bit Score: 654.134
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
15790414    1 MDVGSPEAFSESGTLGVEEEFFVVDEHGVPTAGSDELVYE--GEPPEPIAGRLDHELFKFVVETQTPTLNGVAEAPAAIR 78 
76802324    1 MDLGSREAFDRTGTLGIEEEFFVVDEYGRPTAGTDELVYE--NEPPEPLKDRLDHELFKCVIETQTPTIGSLSAADDALA 78 
55377703    2 DATGSAEHFTRMGTLGIEEEFYVVDEFGRPTSGTDELVYE--TEPPAVLDGRLDHELFKCVIETQTPRIDDPANAGDHLR 79 
110668475   1 MDVGSADAFDRMGTLGVEEEFFVVDDSGQPTAGIQELIYDynHPPAGVLADRLDHELFQFVIETQTPLLEDVSAVSESVQ 80 
169236149   1 MDVGSPEAFSESGTLGVEEEFFVVDEHGVPTAGSDELVYE--GEPPEPIAGRLDHELFKFVVETQTPTLNGVAEAPAAIR 78 
222479383   1 MELGSRDAFARMETLGIEEEFYIVDADGRPTSGIDDLVYG--RDPPAEVPEGFDHELFKCTIEAQTELIEDPSNAVDALS 78 
257388286   2 EETGSAAAFDRMGTLGIEEEFYVVDEYGRPTAGSDELVYE--SDPPTILDGRLDHELFKTVVETQTPTLDGLDDARSALE 79 
257051492   1 METASESPFTELGTLGIEEEFFVVDEYGRPVSGTDTLVYN--SEPPAILENRLDHELFKFVIESQTPVIEDPGDAAATLS 78 
284165367   1 MERGSRDSFTRMGTLGIEEECFVVDDDGRPTSGTDELVYE--HDPPEILEGRLDHELFKFVIETQTPLIEDPADSRETLL 78 
289580384   1 MERGSPDSFTRMGTLGIEEECFVVDEHGRPTSGTDELVYE--HDPPEILADRLDHELFKFVIETQTPLIEDPSNAREVLL 78 
292655816   1 -----------MGTLGVEEEFYIVDADGRPTSGIDDLVYG--PEPPEPLAGRLDHELFQFTIETQTPLIEDPDEAGAAVS 67 
300710923   1 METGSAENFERMGTLGIEEEFFVVDESGRPVSGTDELVYA--NDPPGVLADRLDHELFKCVIETQTPIIGSLPEAGDALR 78 
15790414   79 EVRAALVAYASEHGLRIAGAGLHPGARWREHEHAEKPRYRSQLDRIQYPQHRNTTAGLHIHVGVDDPDKAVWVSNRMRWH 158
76802324   79 EVRKALVSHAETHGFGIAAAGLHPAAKWRELDHAEKPRYRAQLDRIQYPQHRNTTAGLHIHVGVDDADKAVWVANELRWY 158
55377703   80 SVRDALVDHAEANGFGIAAAGLHPLAKWRELEHAEKPRYKSQLDRIQYPQHRNTTAGLHVHVGVDDADKAVWVANELRWH 159
110668475  81 AVRDALVTHAADHGYRIAAAGLHPTAKWRERNHVEKPRYQSQLDRIQYPQHRNTTAGLHVHVGVDDPDAATWIANELRWY 160
169236149  79 EVRAALVAYASEHGLRIAGAGLHPGARWREHEHAEKPRYRSQLDRIQYPQHRNTTAGLHIHVGVDDPDKAVWVSNRMRWH 158
222479383  79 TVRAALVDHAAADGYRIAAAGLHPAAKWRELEHAEKPRYQAQLDRIQYPQHRNTTAGLHVHVGVDDADKAVWIANRLRWH 158
257388286  80 DVRNALVDHAEANGFRIAAAGLHPLAKWRELEHAQKPRYRSQLDRIQYPQHRNTTAGLHVHVGVDDADKAVWIANELRWH 159
257051492  79 AVRGALVEHARDHGFEIAAAGLHPGARWRELEHAEKPRYRSQLDRIQYPQHRNTTAGLHVHVGVDDAEKAVWIANKIRWH 158
284165367  79 EIRRALVDHATDHGYRIAAAGLHPLAKWQELEHAEKPRYRSQLDRIQYPQHRNTTAGVHVHVGVDDADKAVWIANELRWY 158
289580384  79 EIRRALVDHAEHHGFQIAAAGLHPLARWRELEHAEKPRYRAQLDRIQYPQHRNTTAGVHVHVGVDDADKAVWIANELRWY 158
292655816  68 TVREALVDHAAAHGYRIAAAGLHPAAKWRELDHATKPRYQAQLDRIQYPQHRNTTAGLHVHVGVDDADKAVWVANELRWY 147
300710923  79 EVRDTLVSYAAAHGYRIAAAGLHPAAKWRELDHAEKPRYRSQLDRIQYPQHRNTTAGLHVHVGVDDADKAVWVANEIRWF 158
15790414  159 MPVLLALSANSPYWNGFDTGLASARAKIFEGLPNTGLPTAFESYAAFQAFERRMVEHGGIEDRGELWYDVRPHSGHGTVE 238
76802324  159 MPVMLALSANSPYWNGFDTGLQSARAKIFEALPNTGMPTAFEDFESFQSFERTMVETGSINDRGELWYDVRPHSEHGTVE 238
55377703  160 LPLMLALSANSPYWNGFDTGLQSARGKIFEALPNTGMPTTFDDYDAFETYEQRMLETGSIDDRGELWFDVRPHSGHGTVE 239
110668475 161 LPPLLALSANSPYWNGFDTGLASARAKIFEALPNTGMPTRFEDFEAYYQLEKRMVETGSIKDRGELWYDVRPHTGHGTVE 240
169236149 159 MPVLLALSANSPYWNGFDTGLASARAKIFEGLPNTGLPTAFESYAAFQAFERRMVEHGGIEDRGELWYDVRPHSGHGTVE 238
222479383 159 CPVLLALSANSPFWNGFDTGLASARAKIFENLPNTGIPSAFDDFDAFQRYERRMVERGSIADRGELWFDVRPHTGHGTVE 238
257388286 160 LPLVLALSANSPYWNGYDTGLASARAKIFEGLPNTGMPTAFESYAAYEQFERRMVETDSIRDRGELWFDVRPHSGHGTVE 239
257051492 159 LPIVLALAANSPYWNGFDTGLSSARAKLFEGLPNTGMPTTFDSFESFHRFEQRMIETDSISDRGELWFDVRPHTEYGTVE 238
284165367 159 VPIILALSANSPYWNGYDTGLQSARAKIFEALPNTGMPTYFEDYEAFDRFERRMLETESIEDRGELWYDVRPHTAHGTVE 238
289580384 159 VPIMLALSANSPYWNGFDTGLQSARAKLFEGLPNTGMPTYFEDYEDFDRFERRMLATDSINDRGELWYDVRPHTAHGTVE 238
292655816 148 LAPLLALSANSPFWNGFDTGLASARAKVFENLPNTGMPTAFDDFEEFQRFERRMVEYGSIDDRGELWYDVRPHTGHGTVE 227
300710923 159 LPIMLALSANSPYWNGFDTGLASARAKVFEGLPNTGMPTSFESFEEFATFERLLVERGSINDRGELWYDVRPHSEHGTVE 238
15790414  239 VRAPDAQADPAVVDAFVEYAHALVTEYAQRYDd----------------HPDPfsVTGLRRELLDANKWRAMRDGHDASF 302
76802324  239 VRTPDGQADPDHVLAFVEYTQALVEDLSARYE-----------------DGES--GANHRRELLDENKWRALRHGHDAEL 299
55377703  240 VRAPDGQADPDRVLAFVEYVHELVVDLAERYE-----------------DGES--GRRLRREFLDENKWRAIRHGQSAEL 300
110668475 241 VRTPDAQADPSVTVAIVEYIHALVMDFAARYA-----------------DGES--GTKVRREILDANKWHAMRYGRDAEF 301
169236149 239 VRAPDAQADPAVVDAFVEYAHALVTEYAQRYDd----------------HPDPfsVTGLRRELLDANKWRAMRDGHDASF 302
222479383 239 VRAPDAQRDPGVTLAFVEYVHALVVDYAERYA-----------------DGES--PPTLRRELLDENKWRAIRHGHDASF 299
257388286 240 VRTPDGQRNPEYVLAFVEYVHALVASLADQFE-----------------DGAS--GTDTRREYLDENKWRAMRHGHDASL 300
257051492 239 VRTADAQADIDRVLALVEYVHELVLDLAARYE-----------------DGET--ITAVRRELLDENKWRAIRHGREASF 299
284165367 239 LRTPDGQADPGIVLAFVEYAHALVEALAEEYE-----------------DGADgyGRTHRRELLDENKWRAIRHGHEASL 301
289580384 239 LRTPDGQADPDLVMAFVEYAHALVEALAEEYE-----------------DGTP--NSRHRRELLDENKWRALRYGHDASF 299
292655816 228 IRTPDAQTDPERVTDFVEYVHALVLDLADRYE-----------------AGES--GTSVRRELLDENKWRATRYGRDTDF 288
300710923 239 VRTPDGQADPEYVLAFVEYVHALVTDLAERYEdradpwaayrssghgprDGEA--GYDHRRELLDENKWRAMRYGHAASF 316
15790414  303 VARETQGAVDLGTVVDRECDRLGVSGIRDVYDDVSGAQQQRRILDTHGEKRLYNHLSL 360
76802324  300 LDRSLEESVPLGELVESECQRLGVSGIRDVYEAESGAEKQRRLLESEGMDALCGSLSV 357
55377703  301 LSRDLSTTRSVEELVEIESDRLGVDGLWELYHRESGAERQRRLRSEEGVMALADSLRL 358
110668475 302 IIPGSMETVTLSEFVDRETNRLGVDGLTTLLAREGGAKKQRRLHASDNIDTLLESLCL 359
169236149 303 VARETQGAVDLGTVVDRECDRLGVSGIRDVYDDVSGAQQQRRILDTHGEKRLYNHLSL 360
222479383 300 ITRDGEDTVSLGEAVADECDRLGIDGIRDVYDAESGSQRQRRLREEGGLDALCDDLML 357
257388286 301 LTRTGS-TAPLGELVDRECDRLGIDGLRTLYDRESGANRQRRLR-KQGVATLADDLVL 356
257051492 300 ITRDGAETIDLMTAIERDRSRLDLDRLASLVAAESGATRQRRLA-EDSVDRLYSSLLV 356
284165367 302 IDREMEGTIDLGELVDRECERLGIDGIKRVYERDSGAQRQRRLLEEEGPDALCESLLL 359
289580384 300 IDRDLEGTVDLGEVVDRECNRLGIDGIRQVYERESGAERQRRLLASGGPDELCGSLLL 357
292655816 289 IAPDSEGVVSLVSFVETESDRLGVDGLRSLLDAESGTAVQRRIHEESGLDGLCEHLTL 346
300710923 317 IDRDHSGVISLSEVVDRECDRLDVSGIGRLYDAESGASRQRRIRRESGPEALYESLVL 374
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