Conserved Protein Domain Family
PRK13307

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PRK13307: PRK13307 
bifunctional 5,6,7,8-tetrahydromethanopterin hydro-lyase/3-hexulose-6-phosphate synthase
Statistics
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PSSM-Id: 183964
Aligned: 28 rows
Threshold Bit Score: 534.592
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
148643273   1 MYNIGEALIGDGNELAHIDLIIGEKEGPVGQAFANGLSNLSVGHTPLTTVIRPNLMTKPATLIIPKVTVGDLDDAAKVFG 80 
288561387   7 TMFIGEALIGDGDELAHVDLLIGRKDGPVGNAFANGLSQLSVGHTPLLSVIRPNLMTKPATIIIPKVTVGDLDDASKIFG 86 
162329870   1 MIKFGEAILGTDLK-AIVNVIIG-KGTEIDTAFTNALTR---RPSPIFANLRDNLIVRPLTIVVPQNDINSEIQVELLNG 75 
84490278    4 IYEIGEALIGDGPELAHIDLIVGSKQGPVGTAFATNMASMSVGHTPLLSVIRPNLPTKPATLIVPKVTVQNLDDASKIFG 83 
161484927   1 MYRIGEALIGSGNEVAHIDLIIGDKEGNAGAAFANGLTNLSLGHTPLLSVVRPNLMTKPATLIVPKVTVSCLEDADKVFG 80 
304313833   1 MYRIGEALIGSGNEVAHIDLIIGDKEGNAGAAFANGLTSLSLGHTPLLSVIRPNLMTKPATLIVPKVTVSCLEDADKVFG 80 
289192383   1 MIKFGEAVLGNEIK-AIVNVALG-KDKGIDEVFTNALTR----GNCVFANLRPNLIVKPLTLVVPRHNIESDIQDELFQG 74 
261403292   1 MIKFGEAVLGNEIK-AIINVALG-NDKEINEIFTNALTR----GNCVFANLRPNLIVKPLTLVVPRHNIESDIQDELFQG 74 
256810961   1 MIKFGEAVLGNDEAKAIVNVALG-KGKEIDEVFTNALTR----GSCIFANLRPNLIVKPLTLVVPRHNIESSIQDELFHG 75 
15669638    1 MIKFGEAVLGNEIK-AIVNVALG-KGELIENTFTNALTR----GNCVFANLRPNLIVKPLTLVVPRHNIESEIQDELFQG 74 
148643273  81 PAQTAVGRAVADAVEEGYIPKDIVEDIVINVSVFIDP---AAKNYRKIYQYNYGATKLAIRRAMEGYPSIDKVLAEKDRG 157
288561387  87 PAQTAVGRAVADAVEEGIIPKNKAEEWVINASVLISP---AAEDYRKIYQYNYAATKLAIKRALDGYPDMKKVLYEKDRG 163
162329870  76 VIQYGVAKAIADMGEKEGID----NDLKAVITVSVPDvpfTTINKRKLFQYYYGATKLAINRALSEYPSAEKIKKEKYRA 151
84490278   84 PAQTAVGRAVADAVEEEIIPKDIVEDIVLMVNVFIDP---SAKDYRKIYQYNYGATKLAIKRAFDKYPSVDKVLAEKDRG 160
161484927  81 PAQTAVARAVADSVEEGIIPEEKAEDLVVIVSVFIHP---EAEDYRKIYQYNYGATKLALRRAMEGYPSVRKVLSEKDRG 157
304313833  81 PAQTAVARAVADAVEEGIIPEEKVEDLVVIVSVFIHP---EAEDYRKIYQYNYGATKLALRRAMENYPSARKVLSEKDRG 157
289192383  75 VIQYAVAKAVADL--------DLDEDLKVVVSVNVPEvpiTNLNKRKLFQYFYASTRLAINRALNEYPSKEKVKKEKYRA 146
261403292  75 VIQYAVAKAVADL--------DLDENLKVVISVNVPEvpiTNLNKRKLFQYFYASAKLAINRALNEYPSKEKVKKEKYRA 146
256810961  76 VVQYAVAKAVADL--------DLDEDLKVVVSVNVPElplTNLTKRKLFQYFYASARLAINRALNEYPSKEKVKKEKYRA 147
15669638   75 VIQYAVAKAVADL--------DLDEDLKVVVSVNVPEvpiTNLNKRKLFQYFYASAKLAINRALNEYPSKEKVKKEKYRA 146
148643273 158 THPIMGFRVQKLWSPPYLQVALDLDNLDAMERIINDLPDKERVLIEAGTPLVKKFGVGVVGKIRELRPSAFIIADLKTLD 237
288561387 164 THAIMGFKAIKLYEPPYLQVALDLDNEEAMARIIKQLPNRERILLEAGTPLVKKFGVGIVGKIRELAPSAFIIADLKTLD 243
162329870 152 LHPLVGFRDIKLERPPYLQVALDVPTIESMENIVESLPQSDRIIIEAGTPLIKKYGIEVIEQIREIF-DGFIVADLKTLD 230
84490278  161 THPIMGFKAMKLWNPPYLQVALDLDNEDRMRSIIRDLPKRERILIEAGTPLVKKFGVEIISKIREERPGAFIIADLKTLD 240
161484927 158 SHPIMGFRAVRLWNPPYLQVALDLDSMEEMERIINTLPDRERILLEAGTPLVKKFGVGVVRRIRELRRDAFIIADLKTLD 237
304313833 158 SHPIMGFRAVRLWNPPYLQVALDLDSIEEMERIIDALPNRERILLEAGTPLVKKFGVGVVSRIRELRRDAFIIADLKTLD 237
289192383 147 LHPLVGFRDVRLEYPPYLQIALDVPTMENLEFLLQTIPKSDHIILEAGTPLIKKFGLEVIEVMREYF-DGFIVADLKTLD 225
261403292 147 LHPLVGFRDVRLEYPPYLQIALDVPTMENLEFLLQTIPKSDHIILEAGTPLIKKFGLEVIEIMREYF-DGFIVADLKTLD 225
256810961 148 LHPLVGFRDVRLEYPPYLQIALDVPTMENLEFLLQTIPKSDHIILEAGTPLIKKFGLEVVEVMREYF-DGFIVADLKTLD 226
15669638  147 LHPLVGFRDVRLEYPPYLQIALDVPTMENLEFLLQTIPNSDHIILEAGTPLIKKFGLEVIEIMREYF-DGFIVADLKTLD 225
148643273 238 VGRVEIKMAADETADAVAISGLGTIESIKKAIHETQKQGIYSILDMMNVADFEEKLSALpdDLKPDIVLLHRNVDLEtyK 317
288561387 244 VGRVEVKMAADETADAVAISGLGTIESIEKAIHETRKQGIYSILDMMNVDNFTEKLQQInkDLMPDIVLLHRNVDLEskL 323
162329870 231 TGRIEVRMAFEATANAVVLSGLAPKSTILKGIHECQKCGIMSYLDTINLNNPVELYNKL--ELKPDVLMVHRGIDEEinK 308
84490278  241 VGRVEVKMAADETADAVAISGLGTNESIEKAIHECSKQGIYSILDMMNVSDIPSKLEEL--KLKPNIVLLHRNIDSEtmR 318
161484927 238 VGRIEVKMAADETADAVAISGLGTVESIEKAIHEAQKQGIYSILDMMNVENFVDKLRGL--KYKPDIVLLHRNVDLEtlR 315
304313833 238 VGRIEVKMAADETADAVAISGLGTVESIEKAIHEAQKQGIYSILDMMNVENFVDKLRGL--RYKPDIVLLHRNVDLEtlR 315
289192383 226 TGRVEVRLAFETTANAVAISGVAPKSTIIKAIHECQKCGLISYLDMMNVSEPQKLYDSL--KLKPDVVILHRGIDEEtfG 303
261403292 226 TGRVEVRLAFEATANAVAISGVAPKSTIIKAIHECQKCGLISYLDMMNVSEPQKLYDSL--KLKPDVVILHRGIDEEtfG 303
256810961 227 TGRVEVRLAFEATANAVAISGVAPKSTIIKAIHECQKCGLISYLDMMNVPNPQELYDSL--KLKPDVVILHRGIDEEtfG 304
15669638  226 TGRVEVRLAFEATANAVAISGVAPKSTIIKAIHECQKCGLISYLDMMNVSEPQKLYDSL--KLKPDVVILHRGIDEEtfG 303
148643273 318 AEKgedtsemtEWGNIKSIKKl-IGDGLVAVAGGITPNKVEEATSKGADIIIAGRYIIGSRDVRRAAEDFLAHFPQDPDS 396
288561387 324 RAEgknlddisAWGNIKEIKE--ITGGLAAVAGGITPEKAEEAFEKGADIIIAGRYIIGSGDPRRAAEDFLAHMPVDPNH 401
162329870 309 DNN--------KNRSSLSKEDf-DNNIILGVAGGVSAETVED-LKNKYDILVVGRGITKSREPARVARSIVNKLGDDIEQ 378
84490278  319 DNDgeq---qsEWGNIKDIKSklGKRGLIAVAGGVTPEKVDTALANGANIIIAGRYIIGSSDVRRAAEDFLRYLPQDSDT 395
161484927 316 AERgeelgemsEWGNIREIKEilGPRGLVAVAGGITPSKMQEALDSGADIIVVGRYIIGSRDVRRAAEDFLEHMPQDPDT 395
304313833 316 AERgedigemsEWGNIREIKDilGPRGLVAVAGGITPSKMQEALDSGADIIVVGRYIIGSRDVRRAAEDFLEHMPQDPDT 395
289192383 304 VKK--------EWKF--------KGNCLLAIAGGVGVENVEELLKE-YQILIVGRAITKSRDPGRVIRMFINKMGYDIDT 366
261403292 304 VKK--------EWKF--------KGNCLLAIAGGVGVENVEELLKE-YQILIVGRAITKSRDPGRVIRMFINKMGYDIDT 366
256810961 305 VKK--------EWKF--------KGDCMLAIAGGVGVENVEELLKE-CQILIVGRAITKSRDPGRVIRMFINKMGYDIDT 367
15669638  304 IKK--------EWKF--------KENCLLAIAGGVGVENVEELLKE-YQILIVGRAITKSKDPGRVIRMFINKMGYDIDT 366
148643273 397 MRLALDE 403
288561387 402 MRVVMED 408
162329870 379 YRLYLDE 385
84490278  396 MRLALDE 402
161484927 396 MRLPLDE 402
304313833 396 MRLPLDE 402
289192383 367 YRLYFDE 373
261403292 367 YRLYFDE 373
256810961 368 YRLYFDE 374
15669638  367 YRLYFDE 373
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