Conserved Protein Domain Family
pknD

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PRK13184: pknD 
serine/threonine-protein kinase PknD
Links
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Statistics
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PSSM-Id: 183880
Aligned: 15 rows
Threshold Bit Score: 1461.14
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
166154511   1 MQRYELIRLIGKGGMGEVYLAHDKACSRRVALKRIREDLSGNALLRKRFLREAKIAADLIHPGIVPVYSICSDGEAVYYT 80  
237802724   1 MQRYELIRLIGKGGMGEVYLAHDKACSRRVALKRIREDLSGNALLRQRFLREAKIAADLIHPGIVPVYSICSDGEAVYYT 80  
161611313   1 MQRYDIIRMIGKGGMGEVYLAYDPVCSRKVALKRIREDLSDNELLKKRFLREAKIAADLVHPGVVPVFTICSDSDPVYYT 80  
33241430    1 MERYDIVRIIGKGGMGEVYLAYDPVCSRKVALKKIREDLAENPLLKRRFLREARIAADLIHPGVVPVYTIYSEKDPVYYT 80  
161353805   1 MERYDIVRIIGKGGMGEVYLAYDPVCSRKVALKKIREDLAENPLLKRRFLREARIAADLIHPGVVPVYTIYSEKDPVYYT 80  
161353778   1 MERYDIVRIIGKGGMGEVYLAYDPVCSRKVALKKIREDLAENPLLKRRFLREARIAADLIHPGVVPVYTIYSEKDPVYYT 80  
16752949    1 MERYDIVRIIGKGGMGEVYLAYDPVCSRKVALKKIREDLAENPLLKRRFLREARIAADLIHPGVVPVYTIYSEKDPVYYT 80  
29840435    1 MQRYDIIRMIGKGGMGEVYLAYDPVCSRKVALKRIREDLSDNELLKKRFLREAKIAADLVHPGVVPVFTICSDSDPVYYT 80  
62185260    1 MQHYDIIRMIGKGGMGEVYLAYDPICSRKVALKRIREDLSDNELLKKRFLREAKIAADLVHPGVVPVFTICSDSDLVYYT 80  
76789023    1 MQRYELIRLIGKGGMGEVYLAHDKACSRRVALKRIREDLSGNALLRQRFLREAKIAADLIHPGIVPVYSICSDGEAVYYT 80  
166154511  81 MPYIEGFSLKSLLKSVWQKEVLSKELEEKTSVKSFLPIFDKICATVEYIHSKGVLHRDLKPDNILLGLFGEVVIVDWGAA 160 
237802724  81 MPYIEGFSLKSLLKSVWQKEVLSKELEEKTSVKSFLPIFDKICATVEYIHSKGVLHRDLKPDNILLGLFGEVVIIDWGAA 160 
161611313  81 MPYIEGYTLKSLLKSVWQCDSLPKDLAEQTSVGTFLSIFHKICSTVEYVHSRGILHRDLKPDNILLGLFSEVVILDWGAA 160 
33241430   81 MPYIEGYTLKTLLKSVWQKESLSKELAEKTSVGAFLSIFHKICCTIEYVHSRGILHRDLKPDNILLGLFSEAVILDWGAA 160 
161353805  81 MPYIEGYTLKTLLKSVWQKESLSKELAEKTSVGAFLSIFHKICCTIEYVHSRGILHRDLKPDNILLGLFSEAVILDWGAA 160 
161353778  81 MPYIEGYTLKTLLKSVWQKESLSKELAEKTSVGAFLSIFHKICCTIEYVHSRGILHRDLKPDNILLGLFSEAVILDWGAA 160 
16752949   81 MPYIEGYTLKTLLKSVWQKESLSKELAEKTSVGAFLSIFHKICCTIEYVHSRGILHRDLKPDNILLGLFSEAVILDWGAA 160 
29840435   81 MPYIEGYTLKSLLKSVWQCDSLPKDLAEQTSVATFLSIFHKICSTVEYVHSRGILHRDLKPDNILLGLFSEVVILDWGAA 160 
62185260   81 MPYIEGYTLKSLLKSVWQCDSLPKDLAEQTSVGTFLSIFHKICSTIEYVHSRGILHRDLKPDNILLGLFSEVVILDWGAA 160 
76789023   81 MPYIEGFSLKSLLKSVWQKEVLSKELEEKTSVKSFLPIFDKICATVEYIHSKGVLHRDLKPDNILLGLFGEVVIIDWGAA 160 
166154511 161 IFKhakelKLEQDDEAAVSFDERNICYSSMTIPGKIVGTPDYMAPESLLGVEASEKTDIYALGLILYQMLTLAFPYRRKK 240 
237802724 161 IFKhakelKLEQDDEAAVSFDERNICYSSMTIPGKIVGTPDYMAPESLLGVEASEKTDIYALGLILYQMLTLAFPYRRKK 240 
161611313 161 LSK-----EMQEEVLLDIDIPVTGSMFSNMTIPGKIVGTPDYMAPERLRGTPASESTDIYALGVILYQMLTLSFPYRNKK 235 
33241430  161 VAC------GEEEDLLDIDVSKEEVLSSRMTIPGRIVGTPDYMAPERLLGHPASKSTDIYALGVVLYQMLTLSFPYRRKK 234 
161353805 161 VAC------GEEEDLLDIDVSKEEVLSSRMTIPGRIVGTPDYMAPERLLGHPASKSTDIYALGVVLYQMLTLSFPYRRKK 234 
161353778 161 VAC------GEEEDLLDIDVSKEEVLSSRMTIPGRIVGTPDYMAPERLLGHPASKSTDIYALGVVLYQMLTLSFPYRRKK 234 
16752949  161 VAC------GEEEDLLDIDVSKEEVLSSRMTIPGRIVGTPDYMAPERLLGHPASKSTDIYALGVVLYQMLTLSFPYRRKK 234 
29840435  161 LSK-----EMEEDFLSDIDVRIPGSLFSNMTIPGKIVGTPDYMAPERLRGTPASESTDIYALGVILYQMLTLSFPYRKKK 235 
62185260  161 LSK-----EMKEDVLLDLDIPMPGSMFSNMTVPGKIVGTPDYMAPERLRGAPASESTDIYALGVILYQMLTLSFPYRNKK 235 
76789023  161 IFKhakelKLEQDDEAAVSFDERNICYSSMTIPGKIVGTPDYMAPESLLGVEASEKTDIYALGLILYQMLTLAFPYRRKK 240 
166154511 241 GRKLSYR-DVVLPPIEMSPYREIPPSLSQIAMKAIAINPADRFSSIQELRQALQPYLQGDPEWTVKATLMAKEKSCWKYY 319 
237802724 241 GRKLSYR-DVVLPPIEMSPYREIPPSLSQIAMKAIAINPADRFSSIQELRQALQPYLQGDPEWTVKATLMAKEKSCWKYY 319 
161611313 236 GKKISFR-HQISSPEEIAPHREIPPFLSQVAMKALAADPKVRYASVKELKDDIEQHLQGSPEWTPKTILHTQKAECWKLR 314 
33241430  235 GKKIVLDgQRIPSPQEVAPYREIPPFLSAVVMRMLAVDPQERYSSVTELKEDIESHLKGSPKWTLTTALPPKKSSSWKLN 314 
161353805 235 GKKIVLDgQRIPSPQEVAPYREIPPFLSAVVMRMLAVDPQERYSSVTELKEDIESHLKGSPKWTLTTALPPKKSSSWKLN 314 
161353778 235 GKKIVLDgQRIPSPQEVAPYREIPPFLSAVVMRMLAVDPQERYSSVTELKEDIESHLKGSPKWTLTTALPPKKSSSWKLN 314 
16752949  235 GKKIVLDgQRIPSPQEVAPYREIPPFLSAVVMRMLAVDPQERYSSVTELKEDIESHLKGSPKWTLTTALPPKKSSSWKLN 314 
29840435  236 GQKISLR-HQISFPEEIAPHREIPPFLSQVVMRALAADPRERYRSVSALKADIEQHLQGSPEWTPKIVLHTQDRECWKFH 314 
62185260  236 GKKIHVP-NHIISPEEVAPHREIPSFLSQVVMRALATDPKERYTSVQALKADIEQHLQGSPQWTPKIALHTQDAECWKFH 314 
76789023  241 GRKLSYR-DVVLPPIEMSPYREIPPSLSQIAMKAIAINPADRFSSIQELRQALQPYLQGDPEWTVKATLMAKEKSCWKYY 319 
166154511 320 DPILLSRYFPVLASSPAQWYNFMLSEVEISASTRVEYTVTKSAVHEGMGILFLPSKEAERGEFYCGYGLWFSVQNHELTV 399 
237802724 320 DPILLSRYFPVLASSPAQWYNFMLSEVEISASTRVEYTVTKSAVHEGMGILFLPSKEAERGEFYCGYGLWFSVQNHELTV 399 
161611313 315 ESILLSKYFPMLGVSPALWYSLAISKIESFSEVRLEYTLLRKGLEDGFGILLPPSEGVDHGDFYHGYGFWLHIKNSVFSV 394 
33241430  315 EPILLSKYFPMLEVSPASWYSLAISNIESFSEMRLEYTLSKKGLNEGFGILLPTSENALGGDFYQGYGFWLHIKERTLSV 394 
161353805 315 EPILLSKYFPMLEVSPASWYSLAISNIESFSEMRLEYTLSKKGLNEGFGILLPTSENALGGDFYQGYGFWLHIKERTLSV 394 
161353778 315 EPILLSKYFPMLEVSPASWYSLAISNIESFSEMRLEYTLSKKGLNEGFGILLPTSENALGGDFYQGYGFWLHIKERTLSV 394 
16752949  315 EPILLSKYFPMLEVSPASWYSLAISNIESFSEMRLEYTLSKKGLNEGFGILLPTSENALGGDFYQGYGFWLHIKERTLSV 394 
29840435  315 EPILLSKYFPMLEVSPALWYSLAISKIESFSEVRLEYTLLRKGLEEGFGILLPPSEGVDHGDFYHGYGFWLHIKENILSV 394 
62185260  315 ESILLSKYFPMLEVSPALWYSLAISKIESFSEVRLEYTLLRKGLEGGFGILLPPSENVDHGDFYRGYGFWLHIKKNVLSV 394 
76789023  320 DPILLSRYFPVLASSPAQWYNFMLSEVEISASTRVEYTVTKSAVHEGMGILFLPSKEAERGEFYCGYGLWFSVQNHELTV 399 
166154511 400 SLIKNGIEIQKKSQEMISQQYRFAILIEKSDNRIAVFVEQALFILHIDYLPSLGNRLGVIIQDLQGM-SNIAISESIGAL 478 
237802724 400 SLIKNGIEIQKKSQEMISQQSRFAILIEKSDNRIAVFVEQALFILHMDYLPSLGNRLGVIIQDLQGM-SNIAISESIGAL 478 
161611313 395 SLVKNGLEIRKTSRPIKENKEKFFIALEKQNHRLSLIIDHVVWMIHMDYLPGRGGRIGVIIQDVTDVcGNIVVLESSGSL 474 
33241430  395 SLVKNSLEIQRCSQDLESDKETFLIALEQHNHSLSLFVDGTTWLIHMNYLPSRSGRVAIIVRDMEDIlEDIGIFESSGSL 474 
161353805 395 SLVKNSLEIQRCSQDLESDKETFLIALEQHNHSLSLFVDGTTWLIHMNYLPSRSGRVAIIVRDMEDIlEDIGIFESSGSL 474 
161353778 395 SLVKNSLEIQRCSQDLESDKETFLIALEQHNHSLSLFVDGTTWLIHMNYLPSRSGRVAIIVRDMEDIlEDIGIFESSGSL 474 
16752949  395 SLVKNSLEIQRCSQDLESDKETFLIALEQHNHSLSLFVDGTTWLIHMNYLPSRSGRVAIIVRDMEDIlEDIGIFESSGSL 474 
29840435  395 SLVKNGLEIQKTSRHIDGNKEKFFIAFEKQNHRLSLIIDNIVWTIHMDYLPARGGRIGVIIQDVADVcGNIVVLESSGSL 474 
62185260  395 SLVRNGLEIQKTSGNIDVNQEKFFIAFEKQNHRLSLNIDHTVWMIHMDYLPGRGGRIGVIIQDITDVcGNIVVLESSGAL 474 
76789023  400 SLIKNGIEIQKKSQEMISQQSRFAILIEKSDNRIAVFVEQALFILHIDYLPSLGNRLGVIIQDLQGM-SNIAISESIGAL 478 
166154511 479 RVSCLAVPDAFLSEKLYDQAAIFYRKIRDSFPGRKESYEAQFRLGVTLLTQIEEQGG--DLTQALSSFDYLHGGAGAPLE 556 
237802724 479 RVSCLAVPDAFLSEKLYDQAAIFYRKIRDSFPGRKESYEAQFRLGVTLLTQIEEQGG--DLTQALSSFDYLHGGAGAPLE 556 
161611313 475 QVSCLAVPDAFLNEKLYDRAITFYRRIAESFPGRKEGYEAQFRIGIALLEKASESGDseGFTQALGKFEILHNSVAAPLE 554 
33241430  475 RVSCLAVPDAFLAEKLYDRALVLYRRIAESFPGRKEGYEARFRAGITVLEKASTDNNeqEFALAIEEFSKLHDGVAAPLE 554 
161353805 475 RVSCLAVPDAFLAEKLYDRALVLYRRIAESFPGRKEGYEARFRAGITVLEKASTDNNeqEFALAIEEFSKLHDGVAAPLE 554 
161353778 475 RVSCLAVPDAFLAEKLYDRALVLYRRIAESFPGRKEGYEARFRAGITVLEKASTDNNeqEFALAIEEFSKLHDGVAAPLE 554 
16752949  475 RVSCLAVPDAFLAEKLYDRALVLYRRIAESFPGRKEGYEARFRAGITVLEKASTDNNeqEFALAIEEFSKLHDGVAAPLE 554 
29840435  475 QVSCLAVPDAFLNEKLYERAITFYRRIVESFPGRKEGYEAQFRIGIALLEKASENSDseGFIQALEEFSTLHNSVAAPLE 554 
62185260  475 HVSCLAVPDAFLNEKLYDRAITFYRRIVESFPGRKEGYEAQFRIGIAVLEKAAEEGDqeGFSQALREFSVLHDSVAAPLE 554 
76789023  479 RVSCLAVPDAFLSEKLYDQAAIFYRKIRDSFPGRKESYEAQFRLGVTLLTQIEEQGG--DLTQALSSFDYLHGGAGAPLE 556 
166154511 557 YLGKALVYQRNGSFVEEIRCLLFALKRYSQHPEIPRLEDHLCFRLYDSLHKHRSEALVFMLLILWIAPEKISVREEKRFL 636 
237802724 557 YLGKALVYQRNGSFVEEIRCLLFALKRYSQHPEIPRLEDHLCFRLYDSLHKHRSEALVFMLLILWIAPEKISVREEERFL 636 
161611313 555 YLGKALVYQRLGEYNEEVKSLLLALKRYCQCPEISRIRDHIVYRLHETLYSNHRLSLVFMLLALHIAPESINATEEEYFV 634 
33241430  555 YLGKALVYQRLQEYNEEIKSLLLALKRYSQHPEIFRLKDHVVYRLHESFYKRDRLALVFMILVLEIAPQAITPGQEEKIL 634 
161353805 555 YLGKALVYQRLQEYNEEIKSLLLALKRYSQHPEIFRLKDHVVYRLHESFYKRDRLALVFMILVLEIAPQAITPGQEEKIL 634 
161353778 555 YLGKALVYQRLQEYNEEIKSLLLALKRYSQHPEIFRLKDHVVYRLHESFYKRDRLALVFMILVLEIAPQAITPGQEEKIL 634 
16752949  555 YLGKALVYQRLQEYNEEIKSLLLALKRYSQHPEIFRLKDHVVYRLHESFYKRDRLALVFMILVLEIAPQAITPGQEEKIL 634 
29840435  555 YLGKALVYQRLGEYNEEVKSLLLALKRYCQRPEISRVRDHVVYRLHEALYSNHRISLVFMLLALHVAPESINASEEEHFL 634 
62185260  555 YLGKALVYQRLEEYNEEVKSLLLALKRYGQRPEISRVRDHVVDRLHEALYSNHRVSLVFMLLALHVAPESINSSEEEHFL 634 
76789023  557 YLGKALVYQRNGSFVEEIRCLLFALKRYSQHPEIPRLEDHLCFRLYDSLHKHRSEALVFMLLILWIAPEKISVREEERFL 636 
166154511 637 RIIYHKQQATLFCQVDKAPLQFRSSKMELFLSFWTGFSLFLPELFRRAGELRDYQALADIFYVAGVSGNREAFMQFSTAL 716 
237802724 637 RIIYHKQQATLFCQVDKAPLQFRSSKMELFLSFWTGFSLFLPELFRRAGGLRDYQALADIFYVAGVSGNREAFMQFSTAL 716 
161611313 635 KNLHGKIQDTLFCNLDLSPIDFRSSKMELLLSYWSGFTPFLPGLFQKYWDLKDYRALADVFYVAADLGNREFLEMYSDLV 714 
33241430  635 VWLKDKSRATLFCLLDPTVLELRSSKMELFLSYWSGFIPHLNSLFHRAWDQSDVRALIEIFYVACDLHKWQFLSSCIDIF 714 
161353805 635 VWLKDKSRATLFCLLDPTVLELRSSKMELFLSYWSGFIPHLNSLFHRAWDQSDVRALIEIFYVACDLHKWQFLSSCIDIF 714 
161353778 635 VWLKDKSRATLFCLLDPTVLELRSSKMELFLSYWSGFIPHLNSLFHRAWDQSDVRALIEIFYVACDLHKWQFLSSCIDIF 714 
16752949  635 VWLKDKSRATLFCLLDPTVLELRSSKMELFLSYWSGFIPHLNSLFHRAWDQSDVRALIEIFYVACDLHKWQFLSSCIDIF 714 
29840435  635 QNLHGKIQDTLFCNLDISPVDFRSSKMELLLSYWSGFTPFLLGLFQRSWDLKDYRALADIFYTAADLGNKEFIEEYSGIL 714 
62185260  635 KNLQGKIHDTLFCSLDISPIDFRSSKMELLLSYWSGFTPFLPGLFQRSWDLKDYRALADIFYTAADLGEREFIDVYGNTL 714 
76789023  637 RIIYHKQQATLFCQVDKAPLQFRSSKMELFLSFWTGFSLFLPELFRRAGGLRDYQALADIFYVAGVSGNREAFMQFSTAL 716 
166154511 717 ANVSDEITFPESLHNQKVAELMFFVKGVEALRNK-DYQKAKKLLWKTPFTLQLYALDIFHIQAFLDEEIESFIDLLQAIY 795 
237802724 717 ANVSDEITFPESLHNQKVAELMFFVKGVEALRNK-DYQKAKKLLWKTPFTLQLYALDMFHIQAFLDEEIESFIDLLQAIY 795 
161611313 715 RENICSTTCTEDIVEFLPHQLEHFFSGVRAISLHePLEKVFAHIEILDPVLILYLFDLFAKDALIHHRGELILSAITLIE 794 
33241430  715 KESLEDQKATEEIVEFSFEDLGAFLFAIQSIFNKeDAEKIFVSNDQLSPILLVYIFDLFANRALLESQGEAIFQALDLIR 794 
161353805 715 KESLEDQKATEEIVEFSFEDLGAFLFAIQSIFNKeDAEKIFVSNDQLSPILLVYIFDLFANRALLESQGEAIFQALDLIR 794 
161353778 715 KESLEDQKATEEIVEFSFEDLGAFLFAIQSIFNKeDAEKIFVSNDQLSPILLVYIFDLFANRALLESQGEAIFQALDLIR 794 
16752949  715 KESLEDQKATEEIVEFSFEDLGAFLFAIQSIFNKeDAEKIFVSNDQLSPILLVYIFDLFANRALLESQGEAIFQALDLIR 794 
29840435  715 RENIRTTTFSKEIVEILPDQLLCFLSGLEALTLQeSIEKVFDGIENLDPVLILYLFDLFAKDALIHGRGEEILKAIALVE 794 
62185260  715 RENIQATTFTEDIVEIFPHQLIHFLSALDAIFLHaPVEKIFSDVDILDPVLIIYLFDLFAKDVLIHGKGEQILDAIQVLE 794 
76789023  717 ANVSDEITFPESLHNQKVAELMFFVKGVEALRNK-DYQKAKKLLWKTPFTLQLYALDMFHIQAFLDEEIESFIDLLQAIY 795 
166154511 796 DPASEEER-DHILVYIIQTHLWNRDLERAYKLLnDRFPLDEELAEYSEAFILWGCYLALTGDRVAVKAHFSRCRykygKS 874 
237802724 796 DPASEEER-DHILVYIIQTHLWNRDLERAYKLLnDRFPLDEELAEYSEAFILWGCYLALTGDRVAVKAHFSRCRykygKS 874 
161611313 795 KYVSSQQYyEHLLPCEVLAYLWMKDEKKVYNLLcNNYEESLWLDDRSPAFVLYGCWLALVEDSSLSYLHLSGCR----ED 870 
33241430  795 SKVPENFYhDYLRNHEIRAHLWCRNEKALSTIF-ENYTEKQLKDEQHELFVLYGCYLALIQGAEAAKQHFDVCR----ED 869 
161353805 795 SKVPENFYhDYLRNHEIRAHLWCRNEKALSTIF-ENYTEKQLKDEQHELFVLYGCYLALIQGAEAAKQHFDVCR----ED 869 
161353778 795 SKVPENFYhDYLRNHEIRAHLWCRNEKALSTIF-ENYTEKQLKDEQHELFVLYGCYLALIQGAEAAKQHFDVCR----ED 869 
16752949  795 SKVPENFYhDYLRNHEIRAHLWCRNEKALSTIF-ENYTEKQLKDEQHELFVLYGCYLALIQGAEAAKQHFDVCR----ED 869 
29840435  795 KYISPQQRyRYLLPYEVLSYLWMKDANKVYDLL-SSYDESSWIDDSSHAFVLYGYWLALAEDSSLAYLHLSGCR----ED 869 
62185260  795 TYVSPQQRhTYLLPYEILAYLWMKEGKKVHELLsAHYDESFWIEDSHWAFVLYGYWLALTEESSLAYLHLSGCR----ED 870 
76789023  796 DPTSEEER-DHILVYIIQTHLWNRDLERAYKLLnDRFPLDEELAEYSEAFILWGCYLALTGDRVAVKAHFSRCRykygKS 874 
166154511 875 ALIGKCVDGDIFDYL----DNLVWWEKKMTLFQSYFLLRCLNESPRRyEKYRQAYLSMENNFFD 934 
237802724 875 ALIGKCVDGDIFDYL----DNLVWWEKKMTLFQSYFLLRCLNESPRRyEKYRQAYLSMENNFFD 934 
161611313 871 ALYPRALIGGFCSPLgiceNQLSYQERRKLLLQKFIFFHCLGMNEER-DNCTVAYDLLSIERSL 933 
33241430  870 RIFPASLLARNYNRLglpkDALSYQERRLLLRQKFLYFHCLGNHDER-DLCQTMYHLLTEEFQL 932 
161353805 870 RIFPASLLARNYNRLglpkDALSYQERRLLLRQKFLYFHCLGNHDER-DLCQTMYHLLTEEFQL 932 
161353778 870 RIFPASLLARNYNRLglpkDALSYQERRLLLRQKFLYFHCLGNHDER-DLCQTMYHLLTEEFQL 932 
16752949  870 RIFPASLLARNYNRLglpkDALSYQERRLLLRQKFLYFHCLGNHDER-DLCQTMYHLLTEEFQL 932 
29840435  870 SVFPRALIGVFCSPLgiceEQLSYQERRQLLLQKFIFFHCLGNSEER-DKCRTAYDSKERSL-- 930 
62185260  871 HVAPRALIGLFCSPLgiceNQWSYQERRNLLLQKFIFFHCLGDDVER-DNCRVAYDLLVKERLL 933 
76789023  875 ALIGKCVDGDIFDYL----DNLVWWEKKMTLFQSYFLLRCLNESPRRyEKYRQAYLSMENNFFD 934 
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