Conserved Protein Domain Family
PRK13012

?
PRK13012: PRK13012 
2-oxoacid dehydrogenase subunit E1; Provisional
Statistics
?
PSSM-Id: 237267
Aligned: 63 rows
Threshold Bit Score: 1546.82
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
?
Aligned Rows:
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
111019557   48 EGVASYLPDIDPDETTEWLESFDGLLDRSGPTRARYLMLRMLERAGEKHVALPALTSTDYVNTIPTENEPWFPGDEETER 127 
119961193   14 SGLTAQLPDRDPEETAEWIESLDALIAEQGTERAQYIMRSLLQRAGARSVGVPMVTTTDYVNTIPVDQEAQFPGNEEFER 93  
21220657    10 PSELDQLPDRDPEETAEWQASLDAVTQAAGPHRAAYLMRRTLERAEGAGLALPKLLETDYVNSIPTADEPTVDGDEAMEQ 89  
116671956   12 SGLTNQLPDRDPEETAEWIESLDTLIREQGTERAQYIMRSLLQRAGAQSVGVPMVTTTDYVNTIPADQEAPFPGNEEYER 91  
29832563     9 PSELDQLPDRDPEETAEWQASLDAVTQAAGPHRAAYLMRRTLERAEGNGIALPKLLETDYVNTIPTSAEPVVDGDEEMEH 88  
94313189     6 PISSASDNDIDTQETREWLDALEGVIAHEGPERAHFLIEQLIRRAHDAGIYLPFSANTAYVNTIPLDNQAHSTGDQGLEH 85  
119714162   12 SDRLVQPRDIDPDETQEWVESLDAVVDHAGQARARELLLRLQRRAQRRGVLMPGWGPSDYINTIPTAAEPAYPGDEDLER 91  
220913936   12 SGLTDQLPDRDPEETAEWVESLDALIREQGTERAQYIMRSLLQRAGAQSVGVPMVTTTDYVNTIPVDQEAPFPGNEEYER 91  
226361706   25 EGVASYLPDIDPDETTEWLESFDGLLDRSGPTRARYLMLRMLERAGEKHVALPALTSTDYVNTIPTENEPWFPGDEEVER 104 
290961060    9 PSALDQLPDRDPEETAEWQASLDAVAKAAGPHRAAYLMRRTLERAEGNGIALPKLLETDYVNTIPTAAEPGIPGDEAMER 88  
111019557  128 RYRAFIRWNAAVMVTRAQRpGVGVGGHISTYASSAALYEVGFNHFFRGKDHPGGGDQIFIQGHASPGIYARAFLEGRIPA 207 
119961193   94 RYRAYMRWNAAVMVHRAQRsDIGVGGHISTYAGAATLYEVGFNHFFRGKDHPSGGDQVFFQGHASPGMYARAFMEGRLTE 173 
21220657    90 RITAWNRWNAAAMVTRGSK--YGVGGHIATFASAAWLYETGFNHFFKGKEGDGSGDQLYIQGHASPGIYARAFLDGRLNE 167 
116671956   92 RYRAYMRWNAAVMVHRSQRpNIGVGGHISTYAGAATLYEVGFNHFFRGKDHPGGGDQVFFQGHASPGMYARAFMEGRLTE 171 
29832563    89 RITAWNRWNAAAMVTRGSK--YGVGGHIATFASAAWLYETGFNHFFRGKEADGSGDQLYIQGHASPGIYARAFLDGRLTE 166 
94313189    86 RIRSFIRWNAIAMVLRAGR-DTNVGGHIASFASAATLYEVGFNHFWHAPSAQHGGDLVFFQGHSAPGFYARAFLEGRLSE 164 
119714162   92 RIRAAVRWNAAVMVHRAQRpGLGLGGHLSTYASTATLFEVGFNHFFRGPDADGDGDQVYFQGHASPGVYARAFLENRLDE 171 
220913936   92 RYRAYMRWNAAVMVHRAQRpEIGVGGHISTYAGAATLYEVGFNHFFRGKDAPGGGDQVFFQGHASPGMYARAFMEGRLTE 171 
226361706  105 RYRAFIRWNAAVMVTRAQRpGVGVGGHISTYASSAALYEVGFNHFFRGKDHPGGGDQIFIQGHASPGIYARAFLEGRIPA 184 
290961060   89 RITAWNRWNAAAMVTRGSK--YGVGGHIATFASAAWLYETGFNHFFKGKEADGSGDQLYIQGHASPGIYARAFLDGRLNE 166 
111019557  208 ERMDGFRQEHShadqGGGLPSYPHPRLLPDFWEFPTVSMGLGPMNAIYQARFNHYLHDRGIKDTADQHVWAFLGDGEMDE 287 
119961193  174 EDLDGFRQEKSk--aGHALSSYPHPRLMPDFWEFPTVSMGIGPMNAIYQAQSNRYLQNRGIKDTSDQQVWAFLGDGEMDE 251 
21220657   168 EQLDNFRREAG----GNGLPSYPHPRRLPWLWEFPTVSMGLGPISAIYQARFNRYLTSRGIKDLTNSHVWAFLGDGEMDE 243 
116671956  172 EDLDGFRQEKSk--aGHALSSYPHPRLMPGFWEFPTVSMGIGPMNAIYQAQSNRYLHNRGLKDTSDQQVWAFLGDGEMDE 249 
29832563   167 HHLDHFRQESG----GNGLPSYPHPRRLPWLWEFPTVSMGLGPLSAIYQARFNRYLTSRGIKDVSQSHVWAFLGDGEMDE 242 
94313189   165 AQMDKFRQEVG----GQGISSYPHPWLMPDFWQFPTVSMGLGPIMGIYQARFMKYLQDRGFGDHRARKVWVFCGDGEMDE 240 
119714162  172 GQLDGFRQELShgglGAGLPSYPHPRLMPTFWEFSTVSMGLSPINAIYQARFNRYLRDRGIKDTSRQHVWAFLGDGEMDE 251 
220913936  172 EDLDGFRQEKSr--aGHALSSYPHPRLMPDFWEFPTVSMGIGPMNAIYQAQSNRYLHNRGLKDTSDQQVWAFLGDGEMDE 249 
226361706  185 ERMDGFRQEHShtdsGGGLPSYPHPRLLPDFWEFPTVSMGLGPMNAIYQARFNHYLHDRGIKDTADQHVWAFLGDGEMDE 264 
290961060  167 SHLDNFRRESG----GDGLPSYPHPRRLPWLWEFPTVSMGLGPLSAIYQARFNRYLTSRTIKDVSASHVWAFLGDGEMDE 242 
111019557  288 PESRGLAHVAATEGLDNLTFVVNCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWDALLHADRDGALVNLMN 367 
119961193  252 PESRGLLQLAANENLDNLNFVINCNLQRLDGPVRGNGKIMQELEAFFRGAGWNVIKVVWGREWDSLLEADTDGALVKIMN 331 
21220657   244 PESTTALTLASREGLDNLTFVINCNLQRLDGPVRANFKIVQELEAQFRGAGWNVIKSLWGTAWDELFQLDTTGALVRRLR 323 
116671956  250 PESRGLLQLAANENLDNLNFVINCNLQRLDGPVRGNGKIMQELEAFFRGAGWNVIKVVWGREWDDLLAKDNDGSLVKIMN 329 
29832563   243 PESTAALALASREGLDNLTFVINCNLQRLDGPVRANFKIVQELEAQFRGAGWNVVKTLWGSAWDELFQLDTTGALVRRLR 322 
94313189   241 PESRGALGMAGREQLDNLVFVINCNLQRLDGPVRGNGKIIQELESEFRGAGWNVIKVVWGSKWDALLARDKDGILAQRMM 320 
119714162  252 PEALGALGVAAREELDNLTFVVNCNLQRLDGPVRGNGKIIQELESYFRGAGWNVIKVIWGREWDRLLDTDIQGALVDLMN 331 
220913936  250 PESRGLLQLAANENLDNLNFVINCNLQRLDGPVRGNGKIMQELEAFFRGAGWNVIKVVWGREWDDLLTRDTNGSLVKIMN 329 
226361706  265 PESRGLAHVAATEGLDNLTFVVNCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWDALLHADRDGALVNLMN 344 
290961060  243 PESTAALALASREGLDNLTFVINCNLQRLDGPVRANFKIVQELEAQFRGAGWNVIKTLWGSAWDELFQLDTTGALVRRLR 322 
111019557  368 VTPDGDYQTYKANDGGYVREHFFGRDPRTKELVANLSDQDIWN---LKRGGHDYRKIYAAYAAAMAHKGQPTVILAHTIK 444 
119961193  332 ETPDGDYQTYKAESGGFVREHFFGKSPQTKDMVADLDDEQIWG---LKRGGHDYRKVYAAYKAATEFKGKPTVILAKTVK 408 
21220657   324 EVPDAQVQTYQTRDAAYIREDFFNKDPQLAEMAKLLSDDKILDcfhFSRGGHESRKVYAAYRAALAHKGAPTVILAQTVK 403 
116671956  330 ETPDGDYQTYKAESGGFVREHFFGKTPQTKDMVADLSDDQIWN---LKRGGHDYRKVYAAYKAATEFKGKPTVILAKTVK 406 
29832563   323 EVPDAQVQTYQTRDAAYIRQDFFGADPALVEMAKLIGDDKILEcfhLSRGGHESRKVYAAYRAAVSHKGAPTVILAQTVK 402 
94313189   321 ACVDGDYQTFKSKDGAYVREHFFN-SPALKALVADWSDDDIWQ---LNRGGHDPHKVYAAYHAAAHHTGQPTVILAKTIK 396 
119714162  332 VTPDGDFQTFKAESGHFVREHFFGRDPRALRLVETLTDEEIWD---LKRGGHDTHKVFAAYDAALRHVGQPTVILAQTIK 408 
220913936  330 ETPDGDYQTYKAESGGFVREHFFGKDPATKDMVADLTDDQIWN---LKRGGHDYRKVYAAYKAATEFKGKPTVILAKTVK 406 
226361706  345 VTPDGDYQTYKANDGGYVREHFFGRDPRTKELVANLSDRDIWN---LKRGGHDYRKIYAAYAAAMAHKGQPTVILAHTIK 421 
290961060  323 EVPDAQVQTYQTRDAAYIRQDFFGKDPALVEMAKLLSDDKILEcfhLSRGGHEARKVYAAYKAAVEFKGAPTVILAQTVK 402 
111019557  445 GYTLGKHFEGRNATHQMKKLTLDDLKNFRDLQRIPISDAELEkdpkMPPYYHPGPDAPEIQYMLDRRRALGGFLPQRRTS 524 
119961193  409 GYGLGPHFEGRNATHQMKKLTMEDLKAFRDHLRIPISDDQLDadlyRPPYYHPGMDAPEIKYLMERRAELGGFVPERRRK 488 
21220657   404 GHTLGRGFASKNANHQMKKLSVDEFKDMRDLLGLPIADSAFVd--gVVPYGHPGADSPEVRYLQERRAALGGPAPARRVH 481 
116671956  407 GYGLGPHFEGRNATHQMKKLTLDDLKEFRDYLRIPISDARLEedpySPPYFHPGAEAPEIAYLLERRAALGGYTPERRPD 486 
29832563   403 GHTLGEGFASKNANHQMKKLSTDEFKQMRDLLELPISDSQFVd--gVVPYGHPGADSPEVRYLQERRAALGGPAPARRTH 480 
94313189   397 GYGMGEAGEAQNITHQQKHMRVETLGQFRDRFGLPLTDEQLA----DLSYLKFEEGSPEHAYLHQRRQALGGYLPSRRRT 472 
119714162  409 GYGLGSHFESRNSTHQMKKLTVEDLIELRDRLRLPIPDHQLDh--dLPPYFKPAEGSPELEYLEECRLRLGGHLPSRRVR 486 
220913936  407 GYGLGPRFEGRNATHQMKKLTVEDLKDFRDYLRIPVSDEQLDadpyRPPYYHPGADAPEIAYLHERRRQLGGSVPERRSR 486 
226361706  422 GYTLGKHFEGRNATHQMKKLTLDDLKNFRDLQRIPISDAELErdpkMPPYYHPGPDAPEIRYMLDRRKALGGFLPERRTS 501 
290961060  403 GFTLGEGFASKNANHQMKKLSTDEFKQMRDLLELPIKDSDFVd--gVVPYGHPGADSAEVRYLQERRAALGGPAPARRTH 480 
111019557  525 PAP-LPMPPDSTY-DVVRKGSGKQQVATTMALVRIMKELLRDKEIGKRIVPIIPDEARTFGMDSWFPSLKIYNRNGQLYT 602 
119961193  489 HTE-VVLPEAKSY-EVAKRGSGKQQAATTMAFVRLLKDLMRDKNFGARFVPVVPDESRTFGMDAFFPTAKIYNPKGQNYL 566 
21220657   482 PLApLPAPADKAF-ASFDKGSGSQNVATTMAFVRLVKDLVRDKETGKRWVPIVPDEARTFGMESLFPSLGIYSPKGQTYE 560 
116671956  487 HKA-IELPEAKTF-DVAKRGTGKQQAATTMAFVRLLKDLLRDKKFGHRIVPIVPDESRTFGMDAFFPTAKIYNPGGQNYL 564 
29832563   481 PLApLPAPADKTF-ASFDKGSGSQNVATTMAFVRLVKDLVRDKQTGRRWVPIVPDEARTFGMESLFPSLGIYSPKGQTYE 559 
94313189   473 GPE-LPVPPLSAFdGQLKASGEGREFSTAMSFVRILNTLLRDKALGKRIVPIVSDESRTFGMEGLFRQIGIWSQQGQTYT 551 
119714162  487 SRP-LVLPGDTAY--AVATLGSHQPVATTMAFVRLLRSLMNDPAIGHRFVPIIPDEARTFGLDALFPTKKIYSPQGQHYL 563 
220913936  487 HEA-VELPDAKSY-ETARRGSGKQQAATTMAFVRLLKDLLRDKKFGHRIVPIVPDESRTFGMDAFFPTAKIYNPGGQNYL 564 
226361706  502 PQP-LPQPADSTY-DVVRKGSGKQQVATTMALVRIMKELLRDKEIGKRIVPIIPDEARTFGMDSWFPSLKIYNRNGQLYT 579 
290961060  481 ALApLPAAADKTF-AAFDKGSGSQNVATTMAFVRLVKDLVRDKQTGRRWVPIVPDEARTFGMESLFPSLGIYSPKGQTYE 559 
111019557  603 AVDADLMLAYKESEIGQILHEGINEAGSTASFTAVGTSYATHGEPMIPLYIFYSMFGFQRTGDGLWAAADQMARGFVLGA 682 
119961193  567 SVDRDLVLAYKESPAGQLIHPGINEAGAVAAFTAAGTAYATHGEPLVPIYVFYSMFGFQRTGDSFWAAADQMTRGFIIGA 646 
21220657   561 PVDRDQLMYYKEAKNGQILNEGITEAGSMADFIAASTAYATHGEAMIPFYIFYSMFGWQRTADQMWQLGDQLGRGFLVGA 640 
116671956  565 SVDRDLVLAYKESAQGQLIHPGINEAGAVAAFTAAGTAYATHGVPLIPVYVFYSMFGFQRTGDAFWAAADQMTRGFIIGA 644 
29832563   560 PVDRDQLMYYKEAKDGQILNEGITEAGSMADFIAASTAYSTHGEAMIPFYIFYSMFGWQRTADQMWQLGDQLGRGFLVGA 639 
94313189   552 PQDASQLSFYKESKDGQILQEGINEAGAMADWIAAATSYSTHGEPMIPFFIFYSIFGFQRFGDLAWAAGDQRARGFLLGG 631 
119714162  564 SVDRGQLLSYQEDTAGVVLHEGLTEAGCTASWTAAGTSHATHDEPMIPIYVFYSMFGFQRTGDLLWAAADQLTRGFLLGA 643 
220913936  565 SVDRDLVLAYKESPAGQLIHPGINEAGAVAAFTAAGTAYATHGVPLVPVYVFYSMFGFQRTGDAFWAAADQMTRGFIVGA 644 
226361706  580 AVDAELMLAYKESEIGQILHEGINEAGSTASFTAVGTSYATHGEPMIPLYIFYSMFGFQRTGDGLWAAADQMARGFVLGA 659 
290961060  560 PVDRDQLMYYKEAKDGQILNEGITEAGSMADFIAASTSYATHGEAMIPFYIFYSMFGWQRTADQMWQLGDQLGRGFLVGA 639 
111019557  683 TAGRTTLTGEGLQHADGHSLLLASTNPAAVAYDPAFSYEIAHIVKDGLRRMyggtpaadgtlkpGFGGEDIFYYITLYNE 762 
119961193  647 TAGRTTLTGEGLQHADGHSPILASTNPAVKTYDPAYGYEIGHIIRHGLEEMygpd-----stdgTGEDRNVMYYLTVYNE 721 
21220657   641 TAGRTTLTGEGLQHADGHSPAIAATNPAALSYDPAFAYEIAAIVKDGLRRMyge--------aaPGEDPNVFYYLTVYNE 712 
116671956  645 TAGRTTLTGEGLQHADGHSPILAATNPAVVTYDPAYGYEMGHIIRDGIERMygpgaa-sgegtgAASDKNLMYYLTVYNE 723 
29832563   640 TAGRTTLTGEGLQHADGHSPVIAATNPAALTYDPAFAYEIAVIVKDGLRRMyge--------aaPGEDPNVFYYLTVYNE 711 
94313189   632 TAGRTTLNGEGLQHEDGHSLVWGGTIPNCVCYDPTFAFELAVIIQDGLRRM-------------LQMQEDVYYYITVMNE 698 
119714162  644 TAGRTTLNGEGLQHQDGHSQLLAATNPACVSYDPAYAYEIGHIVRDGLRRMyge--------paLGEDPDVFYYLTLYNE 715 
220913936  645 TAGRTTLTGEGLQHADGHSPLLASTNPAVVTYDPAYGYEMGHIIRDGLERMygeks---dggtdVSQDKNLMYYLTVYNE 721 
226361706  660 TAGRTTLTGEGLQHADGHSLLLASTNPAAVAYDPSFSYELAHIVKDGLRRMyggt-----dgvdGFGGEDIFYYITLYNE 734 
290961060  640 TAGRTTLTGEGLQHADGHSPVIAATNPAALTYDPAFAYEVAAIVKDGLRRMyge--------aaPGEDPNVFYYLTVYNE 711 
111019557  763 PYSQPAEPADlnV-EGLLKGMYLFkksqasgdsasnnghsagsapqhghsagsapqhghsagsapqhahsagsapqhaHS 841 
119961193  722 PITQPAEPDNl-DiNGLLKGIYKLada------------------------------------------------petTG 752 
21220657   713 PMPQPAKPSG--VdEGIVKGLYRFntae----------------------------------------------taglTP 744 
116671956  724 PITQPNEPENl-DvNGVLKGIYRV------------------------------------------------------SA 748 
29832563   712 PVPQPAKPAGlgIdEGIVKGLYRFntae----------------------------------------------sadlSP 745 
94313189   699 NYEHPAMPEG--AeQDILKGMYAFr----------------------------------------------------rTS 724 
119714162  716 PIVQPAEPDDv-DiEGILAGMHRIs----------------------------------------------------pAP 742 
220913936  722 PIVQPAEPENl-DvQGVLGGIHRIs-----------------------------------------------------AS 747 
226361706  735 PYTQPAEPENl-NvQGLLKGMYLFrkseasg----------------------------------------ssvqsdgHS 773 
290961060  712 PMPQPAKPGVagVdEGIVKGLYRFntae----------------------------------------------saglSP 745 
111019557  842 AGSAP-RAQILVSGVTMPEGLRAQELLADEWGVAADVWSVTSWGELRRDGIESERQALRDPGTDAPLPYVTQALSDAAGP 920 
119961193  753 NGNRP-TATILASGVSVPWALEAQRILNEDWNVAAEVWSVTSWNELRRDGLAAEEHAFLNPGQPARTPFITEQLKDTNGP 831 
21220657   745 AANAP-RIQLLGSGTAIHWTLKAQRLLAEEWGVAADVWSATSWTELRRDAMDADAALLRGEDR---VPYVRRALQGAEGP 820 
116671956  749 SGAEGpKSQILASGVSVPWALEAQRILAEDWGVSADVWSVTSWNELRRDGLAAEEEAFLNPGEPARIPFVAQQLADAQGP 828 
29832563   746 AANAP-RIQLLGSGTAIHWVLQAQRLLAEEWGVAADVWSATSWTELRRDALEADAALLRGEER---VPFVRQALHGAEGP 821 
94313189   725 NGEAP-RVQLLGAGTIFREVIAASAMLEQHWGVQADLWGCPSFTELARQGNEVIRWNLLHPDEAPRTSHVEHCLADTRGP 803 
119714162  743 ASERP-GAQILASGIAVPWALEAQAMLHDDWDVHADVWSVTSWNELRRRALTIDDWNHVHPDGPRRVPYVTRRLLGQRGP 821 
220913936  748 GVEGP-KAQILASGVSVPWALEAQRILAEDWSVSADVWSVTSWNELRRDGLAAEEEAFLNPEQPARKPFVAQQLADASGP 826 
226361706  774 AGSTP-RAQILVSGVTMPEGLRAQQMLADEWGVAADVWSVTSWGELRRDGIESERQALRDPGTDAPLPYVTQALSDAAGP 852 
290961060  746 VANAP-RVQLLGSGTAIHWALEAQKLLAEEWGVAADVWSATSWSELRRDALEADAALLRGEER---TPYVRQALQGAEGP 821 
111019557  921 FVAASDWMRAVADRIRQWVPGSYTTLGTDGFGFSDTRPAARRYFNVDAESIVVAVLSALAGEGTLDRSKAVEAANRYRID 1000
119961193  832 VIAVSDYMKAVPDQIRQFIPNDFASLGADGFGFSDTRQAARRYFKNDTHSIVAKTLQLLAARGEVEEGAPSYAIDRYKLL 911 
21220657   821 VLAVSDYMRQVPDQIAQWVEQDYSSLGADGFGLSDTRDAARRHFGVDAESIVVAALAQLARRGEVKATAVKEARERYGL- 899 
116671956  829 VVAVSDYMKAVPDQIRQFLPNQFASLGADGFGFSDTRAAARRFFKNDTHSIVVKTLQMLAARGDVEEGAPSYAMDRYKLL 908 
29832563   822 VLAVSDYMRQVPDQIAQWVEQDYSSLGADGFGLSDTRDAARRHFGVDAESIVVAALAQLARRGEVKATAVKEARERYGL- 900 
94313189   804 VIAATDYVRALAEQIRPFVPRAYTVLGTDGYGRSDTREQLRDFFEVDRRWITLAALKALVDEGTLERGVLSQAIAKYGID 883 
119714162  822 VVAVSDWMRAVPDQIAPFVDADWSSLGTDGFGLSDTRAALRRHFRVDPPWIVARVLAHLARQEQVDQTAPARAIKRYQAT 901 
220913936  827 VVAVSDYMKAVPDQIRQFVPNEYATLGADGFGFSDTRAAARRYFKNDTHSIVVKALQMLAARGEVEAGAPAYAMDRYKLL 906 
226361706  853 FVAASDWMRAVADQIRQWVPGSYTTLGTDGFGFSDTRPAARRYFNVDAESIVVAVLSALAGEGTLDRSKAVDAATKYRID 932 
290961060  822 VLAVSDYMRQVPDQIAQWVEQDYSSLGADGFGISDTREAARRHFGVDAQSVVVAALAQLARRGEVKATSVKEARERYGL- 900 
111019557 1001 DVRaaAVSYAD 1011
119961193  912 DVNagTTGGAG 922 
21220657       -----------     
116671956  909 DVNagTTGGAG 919 
29832563       -----------     
94313189   884 PEK--PYPLRA 892 
119714162  902 SLHag------ 906 
220913936  907 DVNagTTGGAG 917 
226361706  933 DVRaaAVSYTD 943 
290961060      -----------     
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap