229358030   1 MNPEIKRLRDKA---DELTRLRIQSAELLMNADTLTVFRTFPLLLHYNHPSLPGYT-----KGDTPTGIHQF-NVNKKQK 71  
192362009  16 DRKQLTLLRRRF---LSLNEQRVARTLTNLSERQQQFMQLLPLLFHVNHPMLPGYI-----SGATPAGVYAY-QPDKDSL 86  
90023240   17 DRQNLTLLRKRF---LSINTDRLERMRSALNSHQQLCLDALPLLFHTNHPMMPGFV-----SRSTPARLCNF-KPDKDIL 87  
120553429  17 DRKTLRRLRDRF---LLVNQQRWQRACSALTYRQQMVLELLPLVFHRNHPALPGYL-----DGNCPDGFSGY-TPGQEVL 87  
297568883   1 -----MGLKEKIaryHLYNEERIAKSVLLNPHKSNIIFAAVPYLLHVNHPDLPGYLn----EPAAPCGICNY-NPATAFS 70  
83643198   16 DRKVLKTLCQRF---ITLVEHRLQRTRLALTPRQQVVLELLPLLFHVNHPLLPGYV-----SRTTPHRLVNY-EPDKNVV 86  
292493536   7 CTLLHKDIRQRF---FALNRHRLGRVRESLRPRQRVFLDALPLLFHTNHPLLPGFS-----GTRTPCGISNY-SPPVTAI 77  
196155755   6 PLSVQQNLTIRLlrvLRYNKARIERALTLMPEKHRPLFHVLPFLVHVNHESLPGFVaplstGESVPFGISNYsFRTDIEK 85  
254784497  16 DRQNLTKIRKRF---LAINQDRLTRMRDALTVRQQLVLDAIPLLFHTNHPMMPGFE-----SRDTPAGVCHF-KITKGAV 86  
304309746  16 DRKQLKTLKGRF---LAVNAERLRRTLEGLSPKRQQFLHALPLLLHVNHASLPGYI-----TPKTPVGVRHF-VPEKHHL 86  

229358030  72 KQLAELFPY-QEEPQKkaqatnlitKPTdlkiqlnnllsfqdepqkkpqqaDLIGLYAMGSTASIGQSSESDLDIWIC-Y 149 
192362009  87 RLARILARS-FTYTRDlv------eTTP-----------------------GIDALFLMGSVGSIAHTAGSDMDIWVC-H 135 
90023240   88 QLGRRVARS-FTLGYD---------PSLe---------------------eDIYGIYVMGSVGTIAQSESSDLDIWLC-H 135 
120553429  88 DAARRYARS-FHYRDKgt------rKPD------------------------LDSLFLMGSPGTLGHSVASDLDVWLC-H 135 
297568883  71 FEL--FHRFfPGQSVPrgeekm-----------------------lpgnlcAIRSLMTIGSVGTIAQSEKSDCDYWVSvH 125 
83643198   87 AQAQRLSRS-FNYREPar------hHGD------------------------IASLYLMGSTGSIAHSGGSDFDVWLC-H 134 
292493536  78 RAGQSISKG-FSYKKW---------TPPi---------------------hPIYGLFLMGSSGTVAQSKQSDFDIWVC-C 125 
196155755  86 ALLRCFPSE-SHLFAD---------IKQiwp-----------------rqrAVDALVLMGSVGTIAQTDDSDFDFWVCiD 138 
254784497  87 QLGRGIARS-FTASQDav------hEPQ------------------------ITAIFVMGSVGTIAQSESSDLDFWLC-F 134 
304309746  87 LAARNIARA-FTYNGSkl------nEPD------------------------LLGIFLMGSTGTIAQSEKSDLDFWIC-H 134 

229358030 150 PHQMDKQRVQLLKNKSWLITHWAEGY-GVELNFFLIPDNKFRIDNKSD-MTMDACGTSQHLLLLDEFYRTELHIAGKRIL 227 
192362009 136 NPTLDLPALQELERKCQVITHWAASQiHLEVHFFLMTGEHFQTGKCSS-MSSEASGSAQHYLLLDEFYRTALWLAGKVPL 214 
90023240  136 KPGLSKQAVDELEKKCTKISEWAMSL-RLEMHFFTMDYEEFKRGTLSA-LNEESSGSAQRLLLLDEFYRSAIFLGGRIPL 213 
120553429 136 RQDLPASGIRCLERKAEKLSEWAGGL-GVELHVFVFSAADWRAGRQRVeVTGENCGSAQHFLLLDEFYRTSIHLAGQYPL 214 
297568883 126 RSQLGARGMELLAEKCAAIAAWTAKK-GVETHFFLMDIEQTRENSFESaAMEESAGTSLKILLKDELFRTHVLVAGKPLL 204 
83643198  135 RPDLDAMALMELQRKADLVCQWAMEM-GSEMHIFLMDAEAFRSGRHDAaADSEDCGTAQHYLLLDEFYRTGIWLGGAYPL 213 
292493536 126 RPGLPPTDRKILQDKSTLIEAWAANL-GIEVHFFLVDEEEIREGHFES-LSRSSSGSAQRYLLLDEFYRTGLLVAGRSPL 203 
196155755 139 GKQFTSTALSLLQQKLTAIEKWADQTfGIEVHFFLSEIDKVKQNDFGV-AEGESAGSAQALFLKAEFYNTNIVVAGKAPF 217 
254784497 135 KPGLTREQLELLNRKCEKITQWALQC-RLEVHFFLMDNAAFKRGQLSA-LNEESSGSAQRLLLLDEFYRTAIHLAGRTPI 212 
304309746 135 RSDLPPKALQELQDKLTAISRWASGI-GLEAHFFLMDAERFKRGERGD-LSGEDCGSTQHYLLLDEFYRSSLLIAGCAPL 212 

229358030 228 WWQVPFE-HEKNYNEYVKKLYDNGGLNPDDWLDLGGFDRIPAEEYFGATLWQLYKGIDTPYKAVLKTILMEAYSW-EYPN 305 
192362009 215 WWFVPVT-READYRRYSETLLHKRFIKAAEVIDFGGLPFIPANEFIGAGIWQLYKAIASPYKSVLKLLLLEVYASgDTAQ 293 
90023240  214 WWFVPAR-AEKDYENYSSTLLDKRFLSDNLVLDFGDIATIPDGEFIGAGIWQLYKAIESPYKSVLKLLLLEAYVS-EHPN 291 
120553429 215 WWLIPVD-READYDHCRRQLVECRFIQARDYIDFGAVPDIPPAELPGAGIWQLYKGIDAPWKAILKLLLIECYAT-DRER 292 
297568883 205 WWFLPPGlEEKHYHGLVKRLVREHKINPDDYVDLGCVATIPREEIFGACLWQMNKALDSPFKSVIKFAYLELLLQdQQSS 284 
83643198  214 WWLIPPD-QEASYADLAELLLEKRFIKPKDYIDFGGCARIPSNEFVGAGMWQLYKGIDSPYKSVLKLMLVESYAK-EEDT 291 
292493536 204 WWLIPPE-YELHYENLVQELSRKHLLRTNDYLDFGGIPQLPAAEFSSAALWQLNKAIDSPYKSLLKLLLMECYAS-EYPH 281 
196155755 218 WWLTPEKtSEKQYQAIYNSLEKGGSPDLDWFMDLGHLEKLDASELFGAAIWQLGKAMDSPFKSVLKMAKLEVYLA-NIAE 296 
254784497 213 WWFVPPG-NEHEYDEYTDILQQRRFLNSEDVLDFGGIPTIPDSEFLGASRWQLYKGIESPYKSVLKLLLLESYAD-QYPN 290 
304309746 213 WWMVPAY-EEKFYDAYASEMLQKRFLEATDFIDFGGISDFPAGEFVGAGLWQLYKGIDSPYKSVLKIILTEVYAS-EHPN 290 

229358030 306 ---TELIALYYKKRF-----QEQQTD-LE--YLDPYCLMLEKVTSYLNKIND---FKRLEVVRACFYLKTEENLS---KI 368 
192362009 294 dtaTEPLALSLKRAL-----YEREPD-VD--RLDPYVMIYERIERYLCARHQ---DARLELVRRCLYFKINKPLS---RK 359 
90023240  292 ---IDPLSLSFKREV-----FAGEVD-IN--NLDSYLIIYRRIERYLQQKQQ---YKRLELARRCFYFKVNKPLS---RP 354 
120553429 293 ----PLLSASFKQAV-----HNGVIS-AD--ALDPYVLLYQRLEQWLLARDG---ADRLELVRRSLYLKSGLPLS---RA 354 
297568883 285 ---PALFSDKIKRLVtypekLPDQMEmLDpgEIDPYLLLAREIIAFYQQANNrpiRQWADLIRECLFLKTLEMVEsqkHA 361 
83643198  292 ---LPNLSLAYKQAI-----FADRLD-PD--ELDPYVMVYRRLEQSLQSRRE---QGRLELVRRSFYLKIGERLSvfvPE 357 
292493536 282 ---IDLLCRHYKRAV-----YAGKTN-LD--ELDPYVMMLHKVETYLQHRGE---TERLELARCCFYFKANEPLS---RP 344 
196155755 297 ---GQPLCNLLKKHV-----HRGAEApGHvaDIDPYSLMFDELITHYSEHGQ---AEDIAVLRECLYLKCGCALSqplME 365 
254784497 291 ---IQPLSLVFKEMV-----YAGEHD-ID--QLDSYVMIYRHIERYLQEKNA---VRRLELARRCFYFKVNYPLT---RS 353 
304309746 291 ---VECLSVGFKKAL-----YHGETL-LD--HVDPYVMMYRKIERYLESRQE---FRRLELVRHCFYFKVGESLS---RD 353 

229358030 369 CtlNPPTWRRQVLTKFVNRWDWNKDHIADLDNRKKWKVRAVSNAKDILLDTLMASYSKLLRFARD--NNIEGSISAEDLG 446 
192362009 360 NarTKKSWQRVLLEDLTHAWGWNSHQLHMLDNRAYWKSPHVIAERALLVNELNHSYRLLAELNKQ--LGLNAAISTDELQ 437 
90023240  355 SrsNTKSWQRVLMEQLVKDWEWSEADIALLDKRKRWKTNTVAMERSQLVSELNHSYRFLLDFANN--CGVAHAISSDELN 432 
120553429 355 Gm-VGDPWRVELLRSLVEGWGWSSEDLGRLDDRQRWCAEEVMGLRRRVVAELTHSYRLLARLARE--QDAQASISANDIN 431 
297568883 362 K--MGQKSHHKAIMEQMEDWDILPANRQHFLNFRYWQYRDLLAFGSRVHGYLAETYKRLRRVFKEidPEVGLTISERDIA 439 
83643198  358 R---EKSWRRKVMEKLTHEWEWSERELRYLDGRSAWKVDQVIQEKRAVVNELTGCYRFLSSYARE--KGLAAAISARDIN 432 
292493536 345 GraDRPAWRRQLLRMLSASWGWDQARLLQLDSRSEWKSPQVMKERQRLVDQLTHSYRQLSHYVGT--QAKQTPQTQRDLH 422 
196155755 366 D--EKPNFKRRIMASYARQWGWNRKQLSHFDNQQEWNFSERVQLSRRIHRFLLKCYRRISKELSH--HQ--QVMDEKDMT 439 
254784497 354 NpnRDKTWQHRLLESLTEEWGWQRKDLLKLDQRNQWKAPAVHEERSLLKNELSHGFQVLKLFAER--YSVEHDISAEEWS 431 
304309746 354 AsgKPTGWRFQLMERLATQWHWDTAYIKALDNRKRWRVVRVQQERQELVHELNYSYRLLSSFARQ--GAIESSIRQQDMQ 431 

229358030 447 ILSRKLYAAHESLPGKVDLINPKISPDLSEPDLSFIQVPK--NRKNAAG--WYLYNC-SLDSFTLINT-P--TLMYAKYI 518 
192362009 438 VLGRKLHAAFERKAGKVEYINPGISRNLSEPALCFVQDKSvaGES------WQLVRG-SQQDLTLRSV-AvePVRRARSL 509 
90023240  433 ILGRKLQAAFERRPGKIDWINPGISHDLSEPLIALHSEYE--EALKTTL--WTAVTF-DEDSPNAGGE----AIKASPSV 503 
120553429 432 LLGRKLYAAFQRKAGKVELINPGLVPSLAEENLSFHHRSE--QGAAGDG--WLLYRD-LEDPSDAFWQ-P--VIRRAGNL 503 
297568883 440 TLGRKLFTFYEKKPNKIDYIRSVSRYHMTMEDITIHITKY----QERFF--YYAFQG-NLDHNTIREQ-VgaAIRRDDHL 511 
83643198  433 LLGRKLYAAFQRKAGKVEMINPGIAPNLSEDNLAFHHLSS--QAIGAAGngWLLYRNlSNPMDAAFNP----AVKRSNSL 506 
292493536 423 ILGRKLYAAFGRKTGKIEYINLEISSNLREEWLSLYQLDQ---PNSPAG--WILYQG-RFTPGDHGGT----ALKHGHNV 492 
196155755 440 VLGRRLSTYYAKKADKIEFLRRAFDESLYCEKVTIAMRQL---KNGEEV--WSAYAGdLLSKSGIIDEsQ--KITQASSA 512 
254784497 432 ILGRKLQAAFETRPGKITWINPGISSDLTEQLVTFAQ-----SAVERPGniWSALIH-PDGTLTQNPI----HIKTSASL 501 
304309746 432 VLGRRLHAAFERTSGKVEQVNPGMAHDLREDALSLHYIYD--AENPSLDhyWVVQRG-YVKARDIQNTqE--PLRKSRSL 506 

229358030 519 AKLVAWCHMNGLYEEETQLHLYNQGSDLVDKKLNQFIQDLYSVFPIY-IPKASNNALSRPCEIKHLTIFLNLERDPTRHW 597 
192362009 510 VELLVWSQVNGLLVPGTRVDLISKDYQITALQKQQLLQAILQWLPEP--HQPEHQAFTSAARVEKVLMLFNLGVEPQAEL 587 
90023240  504 VELMLWCYYNGLIDNSTRFDLTGC-EEINEYELRRLLNLFQQWLPQT-TSSLPHETFKQSAVPSDAMLLINVAKHPMSQL 581 
120553429 504 AELLVWCYCNGLLSRSTRLNVRAGQSVASVSELKEILDVLAGFLPVP-MPPAPRQALSRAVRPLRNLLLLNVAVDPQAHL 582 
297568883 512 VRLVTWLMVNGMLARHTKLHLTKNFLPIDLADIQILAEKMLDTFPMVdFSKIPPQHLVEQENILRALVVVNFFKEPVKGN 591 
83643198  507 IELLVWAYCNGLLDRSTSVSLASGESHASQYELQQIISSLRSLISLP-LPAVTQQDYRAKARLRATLVYVNVGVDPMADL 585 
292493536 493 TELLVWAYFNGLISHATHLAAYSKNGMPKPVELQALQAQLQKLFPHPgLHGQTLDNYTIPPTIERAVVFINVGIDPMAHR 572 
196155755 513 IALMVWCVSSKIIDTHSKVYLDYNYGEVSELDLNDLLKHLCKYFPPVkVSALPRNNLLAPERITACFAIVNF---PTLRQ 589 
254784497 502 VELYLWCYCNQIVNLTTRYELQQA-PHIEERTLHRLLKVFANWLPLP-LKSLDHNVFKRSAEPVDALFLLNVGSVAQAGL 579 
304309746 507 IELLAWCIFNRLLDESTHISADCEGSDLTETELKRLTQHFFQQFPTG-APVAQESAFSEAARPSAYLLFINVGLDPLREL 585 

229358030 598 ESTSESEDDQQGDIFSYGEDKECLIGSIDLIYRNSWNEVRTLHFNSNQSVIDALHTILGKMHQGA---CPPEQIDLFCYS 674 
192362009 588 HKRGMQMLSAQSDPLGFSGFRANLVLSVDIVQLNSWGELVARHY------------------------------------ 631 
90023240  582 QDHGYQRLSSRSDALRYSGFDENLVVSVDIVIRNSWNEINTRRFEKDTALLDALHEYLQLCLPGTh--HLPPALTVECVG 659 
120553429 583 TERGLHKLSARNDSLGFSGARDNLVVTIDQITLNSWHEVSLQHYAAGDTLIQCLKNVLAQVAINP---AELPDIRVMAPS 659 
297568883 592 KT-----------------------LASTIISENSYGEYFLHDYNTLAQLKNALLTLLTRHYVSRw-------------- 634 
83643198  586 SRRGLHKLSNRNDALGYASERANLVVTLDQVIINSWNEVMVQRYESGDTLVQCLKNYLAALAESEqfgEGLPQLSVLCYC 665 
292493536 573 TRQGIHLTSTQADPLSYGGARENLALSLEMVLLSSWKEVLVIPYRGSQGILDCLSEYLRWAPLSEg--QPPPALTTGCYS 650 
196155755 590 KA---------------------TVEDVSVIYSTSWGET---FLKSGSEVLDTLWYDLQEVSP-----APP------CYV 634 
254784497 580 EQRGIKRLSSQTDALHYSGFGENLIISVDLVLRNSWNELTTRRFDSSTALLDSLQDYLKLSLPGSh--HRPPKLQVECVS 657 
304309746 586 TRRGIHRLSNQTDALSYSAMRHNLVLTVDQVLFNSWGEVLCSRYDGETALLDCLQEFLRRSLPGN----PLPEVQIRCEC 661 

229358030 675 CQFQAQISQAFKSKLNEYIQLRLDSLSqRSV----QTLKTGEENFAFYFEQTGVSVQHLKNLVDIYSHISNKKVSNSALN 750 
192362009     --------------------------------------------------------------------------------     
90023240  660 ETLSNTISQRVKDWFNEIVHCFYAD---KKAanrrYIFEMGNHYYCLQFSGMKLVTRAFTNPNALLAHLGEEQTKPSPII 736 
120553429 660 RGHGQAIARRVSELFADVLRQFFAGGTgPHPl--rYIIEMDQRYFLLQFNGQEPGFVALDSRAALMDALFQPQDSFLPVV 737 
297568883     --------------------------------------------------------------------------------     
83643198  666 PTRAGAIAQRVNQLFQQVVFCYFSD---KERarsrYILQMEDRYFVLQFVDDQPRFTALEDYVGLCEFLAQPQKHYSSIV 742 
292493536 651 TSHGRHIAERIEILFQNIVSCYYQNYPpHTR----YVLGIGQDYFILWFENDSLYTEKWPSREALLKALGRPQPIFTPVV 726 
196155755 635 MVPRGNQQARILGEFLEAHELNFTVLY----------------------------------------------------- 661 
254784497 658 PNHANTIATRTRDWLNEIIHCYYGGEYmSATr---YVFEMAGLFHILQFKGPRLITRQYPSLDAVLDALGDAQPSISPIY 734 
304309746 662 PTRPTAIVARVEELFA---DLSLHFCQsERAattrYLLEMEQQYFLLRLKDGVPLLKRAQSREELLERLAEPHPRYSPIV 738