182413122   6 VSYLWDDTVAASL-----------DPVARLVYRSNLLGSDQRITNTGGGNTSSKLTERDpLTGAPVEVLWVKGSGGDLRT 74 
256392699   1 MRNRWDENEAPADg----------dLLDQCVYVSRLLGADPDLVLHGGGNTSVKTVSRD-ALGRDVDSLQVKGSGWDLAT 69 
158521906   3 DGNMPTQYDKKAVhailkarpelsPDLAACIHVSRLLGGDPAMVLHGGGNTSVKLVEKD-LFGKELRVLCIKGSGVDMAH 81 
297570263   1 MKNLYDHLEAREFvaar---sdcsEALALRVYTSRLIGREPELVLHGGGNTSVKAVVPN-ILGEEMEVLYIKGSGWDLAT 76 
172037468   1 MKSLWNDQDAAKYk----------tDLALRVYTSRLLGQNPSLVLHGGGNTSVKIRQDN-IVGETEEILYVKGSGWDLAT 69 
170079184   1 MKSLWNDQEAATYq----------gDLALRVYTSRLLGRDPSLVLHGGGNTSVKVTETN-LVGETEEILYVKGSGWDLAT 69 
16329982    1 MKSLWDDQEANQYq----------gDLPQRVYTSRLLGREPSLVLHGGGNTSVKCQVTN-LVGEKEDILYVKGSGWDLAT 69 
170728071   1 MHSLWQNEIAEQLn----------tPLALRVYTSRLLGQEPALVLHGGGNTSVKTQITN-LFGETEEILYVKGSGWDLET 69 
119714666   1 ----MPFAMSPAAs----------aALTDLVRVSRLLGADPALVLHGGGNTSLKATTTD-LTGSTVDTLFVKASGHDLAS 65 
294142249   1 MQSLWHAQTASQFt----------tPLELRVYTSRLLGQEPALVLHGGGNTSVKTQVNN-LFGEPEDILFVKGSGWDLET 69 

182413122  75 SKRENFASLYQPKLLDLQRLyatradkglKSSAEDDMVGMYTHATFNLNPRASSIDTPLHAFLPGRHVDHMHPNAIIAIA 154
256392699  70 IQRPGFAPLRLARLREILEA---------ESLSDSAMMNELRCALLDASAPDPSVETLLHALIPDTFVLHTHADAVLTLT 140
158521906  82 IEPEGFAAMDLAALEPIQGI---------RALSDEEMENQLSRHRLNVRAPAPSVETFLHAFLPHRFVNHTHADAVLGLT 152
297570263  77 IEAAGFPGLDLAWLRRLRVL---------ERLSDEEMVNQFRTHLLDAAAPGPSIETLVHAFLPHRFIDHTHADAIVTLT 147
172037468  70 IEEGGFSGVRIPHLLKLAQL---------RSLSDSQMVNELKTQMIRSNAPSPSVETILHAILPYKYVDHTHADAVVTIT 140
170079184  70 IEAAGFAPVRMNHLLKLAQL---------PSLSDPQMVNELKTQMTVATAPTPSVETILHAILPYKYVDHTHADAIVTIT 140
16329982   70 IEAAGFAPVRMPHLLKLSKL---------TQLSDRQMVNELKTQMTLASAPSPSVETILHAILPFKYVDHTHADAVVTIT 140
170728071  70 IEAEGFAPVKMDVLLKMAGL---------NDLSDSDMVKYQRAAMTDPSAPNPSVEAILHAIIPFAYVDHTHADAIVTLT 140
119714666  66 IDAAGFAPLRLARLREILPP---------VVVPDDLLINELRCALLDAAAPDPSVETLLHALLPRPAVIHSHADALLAVA 136
294142249  70 IEAAGFAPVKMHVLLKMAQL---------TELSDSDMVKYQRAAMIDPNAPNPSVEAILHAIIPFAFVDHTHTDAVVTLT 140

182413122 155 ASANCERLTREIFGDAMAYVPWMRPGFELGLAMQEIVRRQPG--VRAIMMGQHGFIAWDDDDKACYTRTLDFIERAATYI 232
256392699 141 NLDDGEARIREALGEDHIAVPYVMPGFDLAKYCRDQLRGRGDalPQTMILLRHGVFTYGESARAAYDRMIEVVGRAEQYI 220
158521906 153 NRRQAKTVVRQVLGPDVCVVAYEKSGLPLARHVAAAWEKQPA--ADTVVVLNHGIFTFSDDAKTACNRMLEHVRKAEAWL 230
297570263 148 NRHQPEKLLREALGDRIAILPFIMPGFPLAKAMAAAYEENPQ--IEAIILLNHGIFTFADEAETAYGRMIDYVSRAENFL 225
172037468 141 NTAERRQRIKEIYGDRIVIIPYIMPGFDLARLCVQEFEKQKGnnTIGMVLMNHGIFSFGNTAKESYERMIELVTQAEDYL 220
170079184 141 NTPEGLERIKEIYGDRLVIIPYIMPGFDLARLCAEKFAAAAHaqTEGMILLNHGIFSFGATAKESYERMIALVQEAETYL 220
16329982  141 NTANGEERIREIYGDHLVIIPYVMPGFDLARVCAEKFAAEAHggTVGMVLMNHGIFSFGAIAREAYEGMISLVNEAEEYL 220
170728071 141 NTPDGEGMIQELFGKRVFVIPYVMPGFALAKLVHEMTQELKWqsIEGLVLMNHGLFTFSDDAKVAYEKTIDLVTEAEQFI 220
119714666 137 NTPDGRERLADLFGDRVILVDYAMPGPDLVAACAAAWSREGGnhTQGVVVLGHGLFTVGSTPDEAYQHHVDLVTDVAGLL 216
294142249 141 NTSNAESFIEQVYGKRVLVIPYVMPGFALAKRVYKMTQDIDWqsIEGLVLMNHGLFTFSDDAKTAYENTIKLVTEAEKFI 220

182413122 233 ---------------------------------------------------------------EeryaARGGdaaaFGGA 249
256392699 221 ---------------------------------------------------------------A----ERTRa---ARST 230
158521906 231 --------------------------------------------------------------------AAHQ-------- 234
297570263 226 tkvaqewsargedlkalghgtgvgaansgsgsfsadlrpaseasaaadepaatgvggprpgadV----TGARe---GVNA 298
172037468 221 --------------------------------------------------------------------KQHQ-------- 224
170079184 221 --------------------------------------------------------------------QQQG-------- 224
16329982  221 --------------------------------------------------------------------KNQGvw------ 226
170728071 221 ---------------------------------------------------------------E----AKLCl---KSEA 230
119714666 217 ---------------------------------------------------------------R----ASSTr---GQSQ 226
294142249 221 ---------------------------------------------------------------E----ANLCi---NAEE 230

182413122 250 KYQ-----TLDEPRRRA-----TLAAV-LPWLRGQVSr-----ERRFV-----------GTIQDDTPILRFVNSHDAPRL 302
256392699 231 PTPt----MQASPSETT-----APDILdVASLRQAVS------RVAGVpm--------iATRSADAASAEFCYRPDLATV 287
158521906 235 --------PTAVPETMAappgaVCARV-VQVIRGACAhvdrqgKPTRLl----------ADLRTDTDLVAISLDRSAQKI 295
297570263 299 SGA-----EVLASPPPP-----APVEL-LPLLRG--A---------LNrgledqrlcfsLDWRRDTDLQAALARPDGREL 356
172037468 225 --------AWHIPQKAVntpdtLLGET-LAQLRYQVS------VAAGFpv--------iLSLQQTEKTLSFAQREDINII 281
170079184 225 --------AWQIPQRSVktsdtPIAKT-LAQLRYDVS------QVAGFpv--------iLKGDRRPEILNFTQREDLGRI 281
16329982  227 ------qiSYGQPQKST-----TENRLaLAQLRCDAS------KIAGFpl--------vMRQYQDEASLSFSQRPDLAHI 281
170728071 231 IEEttghdPSGYPEQEI-----SIDLIeLAQIRKLVS------AQKGApq--------vALLNSSLPSCHIASHPKLRDI 291
119714666 227 PAAp----LPPA------------DPLaVARLRQSLS------RAAGHpm--------vVTSHRDNEVASFVGDDRLLAA 276
294142249 231 REEad-ekSLEYLDENI-----NIDLLeLAKIRKLVS------AQKGYaq--------vALLNSSKGSCHIASHPELKSI 290

182413122 303 AELGTSCPDHFLRTKIKPLYVDWNpqsEDLAALKGKLAAGLEQYRRDYAAYY-DRCKHA--NSPAMRDPNPTVVLIPGLG 379
256392699 288 SQQGPATPDHVIRTKRLPMT-----------------GRDVDAYAKEYVAYYeSQESPDadPPTTMVDPAPRIALDRDLG 350
158521906 296 CASGVLTPDHAIRTKNRIAYLPSIp--DSDEVLKALVDKTVAAYAKEYRRYV-AAHADK--AECPETDPLPRVFLVAGLG 370
297570263 357 FTGGVLTPDHVIRTKNYPLWLDFAg-aSDEAARNAYLKRALADYAAAYQGYF-EEQCAAgkVQKQRLDLLPRVIMVPGLG 434
172037468 282 SQQGPATPDHVIRTKRTPLV-----------------GRDVQGYVKVYETYF-KTNLAQakDNKTMVDPAPRVIIDPELG 343
170079184 282 SQQNPATPDHVIRTKPVPLI-GRD----------------VQGFAAAYKAYF-TNQAPEakEPKTMLDPAPRVILDPELG 343
16329982  282 SQQGPATPDHVIRTKRLP-----------------QLGRDVADYAKKYQEYF-QRNDGKsgEVKTMLDPAPRIILDRELG 343
170728071 292 ATRGPLTPDHVIRTKRIPVILGED------------FETDLSEYASQYIEYF-----ESyqQGQTMLNYAPNFAIWRDKA 354
119714666 277 AQRGPLTPDHVIWTKHSPMI-----------------GTDLDAFVRAEDDYF-TRHATRrgRTLLRLDGAPRVVLDRTLG 338
294142249 291 ANRGPLTPDHVIRTKRVPAILSDN------------IEAELCGYAQDYIEYF-----DRyqSGQTILNYAPSFAIWQGKA 353

182413122 380 MIAWGKDKSESRVTAEFYNCAVEVMRGAEAIDRYVALPQQEAFDIEYWLLEEAKLK-RMp-AEKELARQIAVVIGAGSGI 457
256392699 351 LVAFGRRPKDAGIAADIYRHTIGIVERAEELGGYRALSAADVFSVEYWELEQAKLR-RAg-GTPEFAGEVALVTGAASGI 428
158521906 371 LVGLGVTRKAATVAADIAAHTIRIKHRCGMDA-YRAIAPQHVFDMEFWPFQLKKVA-QH--PALPLEGQVALVTGAAGAI 446
297570263 435 LIGAGTSPAAARIAADIATHTVRAKLRGAALGQYRELEPASIFAMEYWSLEQAKLG-KG--SPRLLEGRTALVTGGGGAM 511
172037468 344 MCAIGKNAKAAGIVADIYNHTIDIIQRGTLLGGYQALPSQDIFDVEYWELEQAKLA-KGg-QTPPFTGEVALVTGAASGI 421
170079184 344 LITVGQTAKAANIVADIYRHTIEIITRAERLSRYQALSQKDIFDMEYWDLEQAKLK-KGg-NPPEFTGEIALVTGAASGI 421
16329982  344 LLTLGTSAKSTAIAGDIYQHTMAIIQRAKGLGGYQALPESDIFVVEYWDLEQAKLK-QAg-NPPMFAGEVALVTGGASGI 421
170728071 355 AISFGKTVKEALIIEDITNHTFDAILTAQQISRYQALSAQEIFDVEYWELEQAKLK-KStsNNTPLLGKVIMVASGSDDV 433
119714666 339 MLTAGRTAGEAARTADIYRHTLGAIELAEALGGYRPVEEEHVFDLEYWSLQQAKLS-RKd-SHRPLSGQVAVVTGAASGI 416
294142249 354 AISFGKTVNQALIIEDITSHTFDAILTAEALGGYQALSPADIFAVEYWELEQAKLKkGPfsHDKPLLGKVAMVTTAATQV 433

182413122 458 GRETAHRLAREGAQLVCVDLMEGAAQSTAKEitdrlglgigVAGsgisncgPALGLGANITDRASIRHMLDQVALAYGGF 537
256392699 429 GRACVKALVARGAAVVGLDVEDAVTSIAPAP--------------------DYLGVVTDVTDSGAVKDAIAQAVDRFGGI 488
158521906 447 GFGVADRLLAAGAVVVAADLDETGLANVCDL----------LSErhg--kdRVESVSFDVTDYDQTERAFMKACLKMGGI 514
297570263 512 ALGIADRLLAAGARVLLADIQPERLQLVVDK----------LQRrfa--peLVQGLKFDVTDPESVRAGFAQLVGQTGGL 579
172037468 422 GKACVASLLKRGAAVVGLDINESITDLHKGT--------------------DFCGLVCDLTDETAIKQALEMAVRRFGGV 481
170079184 422 GKACVESLLKRGAAVVALDINPTIETLCDRP--------------------DFLGLTCDLTDETQIKNALEQAVQYFGGL 481
16329982  422 GKASVAQLLKQGAAVIALDIQPNISELHNRP--------------------DFLGIQCDLTDANAFKQALEQGIAQFGGL 481
170728071 434 REALAAELTSQGANVIELNHEQ------------------------------------DFDTLDKCQEAAETAVIDFGGL 477
119714666 417 GHACAVSLLESGASVVGWDVSPSVRDAISSP--------------------EWLGLAVDVTDSAAVTEAIQRGVEAFGGV 476
294142249 434 GQAVVAHMEILGANVVE------------------------LGE------------HLEFDTLDKCQEAAETAIIDYGGL 477

182413122 538 DAIVVTAGVFVPSDTTGHiPDEKWALTFNINVTGSYLVADEAAKTWRDQGLR---GSLVLTTSANAVVAKKGSVAYDTSK 614
256392699 489 DMLIASAGVFGPSRAMSDfDPQQWHGTLSVNTEAFAALLSQVHGLLKLAPRY---GRVVLIGSKNTAAPGPGAAAYSASK 565
158521906 515 DIVVPNAGIAHVATIEDL-APAAFNRVVSVNLTGTFNTIKASVPIFKRQGTG---GNIIVISTKNVFDPGAAFGAYSSAK 590
297570263 580 DILVPNAGIAQVARLEEL-SAEGFRRVMAVNADGVLLTIREAAKIFRRQNCG---GQIVINSSKNVFDPGAAFGAYSASK 655
172037468 482 DMVILNAGIFPASSPISAlSTEQWRRIMNINLDANLVFMREVHPFLKMAPKG---GRIVVIGSKNVPAPGPGAAAYSASK 558
170079184 482 DMVILNAGIFPPSQAIANlPTDHWRQVLDINLDSNLVLLRECHPFLKLAPKG---GRVAIIGSKNVAAPGQGVAAYSVSK 558
16329982  482 DMLVLNAGIFPVARAIAElSTLEWQKVLNINLDANLTLLRECYPLLKLAPKG---GRVVVIGSKNVTAPGPGLAAYSASK 558
170728071 478 DNLICLDDNSANQLLINT------------------------CEAFLEHGL----SPTVLCVNHNTLPV----------- 518
119714666 477 DILVVAAGIFPTSANLGEmSMQAWRRAMAVNVDAVADLYGQIHPFLAA---GtpyGRVVLIASKNVAAPGPGAAAYSASK 553
294142249 478 DIVICLGD-----------------------DPSNLMLLKACEAFLEH---G--------------INPRVLCVNHGSLP 517

182413122 615 AAASHLVRELAIELAPL-VRVNGVAPATVv---qGSAMFPRDR---VIGSLAKYNIAfaadeptdslVRklaqFYADRTL 687
256392699 566 AAATQLARVAALEWAGDgIRVNVVHPDAVf----DTGLWTPEI---IEARAAHYGMT----------VE----QYKRRNL 624
158521906 591 AGAHQIAKIAAIELAPLgVRTNMVNPDAVf---gDAAVPSKLWeliGPDRMKARGLD----------PEglkeYYRQRNL 657
297570263 656 AAAHQLGKIAALELAEIgVRVNMINADAVf---dADGVSSGLWdlvGPERMQARNLD----------PEglraYYRQRNL 722
172037468 559 AALNQLTRVAALEWGKDkIRINSIHPNGVf----DTGIWTDEV---LETRAKNYGLT----------IE----EYKTNNV 617
170079184 559 AALNQLARVAALEWGSDeIRINTIHPNAVf----DTGIWTPEV---LEKRAKAYGLT----------IE----DYKKNNL 617
16329982  559 AALNQLMRVASLEWAKDnIRLNTIHPNGVf----DTGFWTEEV---LEARAKHYGLT----------VE----EYKGNNL 617
170728071 519 -------------MSSDtIKVLALNCQLSn--------kNGQN---NNQKSAIFNLT-----------------SAIKMM 557
119714666 554 AAVTQLTRVAALEWAPHgIRVNMIHPDAVf----DTGLWTPEL---LEARAEHYGMT----------VE----QYKRRNL 612
294142249 518 VMSDNIIEVLHLNCSASpTLVSLNGSTSLvqktnGEHLETGVF---NLLSAITMMLS----------NE----------- 573