Conserved Protein Domain Family
PRK07773

?
PRK07773: PRK07773 
replicative DNA helicase; Validated
Statistics
?
PSSM-Id: 236093
Aligned: 15 rows
Threshold Bit Score: 1442.63
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
?
Aligned Rows:
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
268315593  15 EEAPPYPlekltggrrrtraqihalhqqaGRVPPQAVELEQAVLGAMLIEPEAIPRALEILTPEAFYDGRHQRIFRAIVR 94  
291296959   1 MATTPLE----------------------GRVPPHNLDAEASVLGSVLLDSEVLDRLEGLLAADAFYKEAHRKIWEAMVA 58  
16331718    1 MAANPAL-------------------------PPQNIEAEECILGGILLDPEAMGRIIDLLVVDAFYVKAHRLIYEAMLS 55  
148821248  12 DSSPPSEd--------------------yGRQPPQDLAAEQSVLGGMLLSKDAIADVLERLRPGDFYRPAHQNVYDAILD 71  
148659818  12 DSSPPSEd--------------------yGRQPPQDLAAEQSVLGGMLLSKDAIADVLERLRPGDFYRPAHQNVYDAILD 71  
253796973  12 DSSPPSEd--------------------yGRQPPQDLAAEQSVLGGMLLSKDAIADVLERLRPGDFYRPAHQNVYDAILD 71  
121635968  12 DSSPPSEd--------------------yGRQPPQDLAAEQSVLGGMLLSKDAIADVLERLRPGDFYRPAHQNVYDAILD 71  
224988441  12 DSSPPSEd--------------------yGRQPPQDLAAEQSVLGGMLLSKDAIADVLERLRPGDFYRPAHQNVYDAILD 71  
54027550   13 PPEPPGEd--------------------fGRQPPHDMAAEQSVLGGMLLSKDAIADVVEVIRPGDFYRPAHQAIYDTILD 72  
152968276  10 DFDAPDDgpsrgrrggrkdrgadgggasfDRMPPQDIAAEQGVLGGMMLSKDAIADVVEVLKGNDFYRPAHELVYEAILD 89  
268315593  95 LFEQNRGVDLLTVTEELRRTGELEQAGDTIYLSELTTRVASAANVEYHARIIAEKALLRRMIEVMTLLVGRAY--DPAAD 172 
291296959  59 LRARRDPVDLVTLSEELRQNGELENVGGLSYLVGLSEQTPTAAYADYYGRIVAEKWTLRKLIAAAGEAMKMAY--DEEGS 136 
16331718   56 LHGQSQPTDLMSVSSWLQDHHHFEAIGGMVKLTQLLDRTISAVNIDRFAALIMDKYLRRQLIAAGHDIVDLGY--ETSKE 133 
148821248  72 LYGRGEPADAVTVAAELDRRGLLRRIGGAPYLHTLISTVPTAANAGYYASIVAEKALLRRLVEAGTRVVQYGYagAEGAD 151 
148659818  72 LYGRGEPADAVTVAAELDRRGLLRRIGGAPYLHTLISTVPTAANAGYYASIVAEKALLRRLVEAGTRVVQYGYagAEGAD 151 
253796973  72 LYGRGEPADAVTVAAELDRRGLLRRIGGAPYLHTLISTVPTAANAGYYASIVAEKALLRRLVEAGTRVVQYGYagAEGAD 151 
121635968  72 LYGRGEPADAVTVAAELDRRGLLRRIGGAPYLHTLISTVPTAANAGYYASIVAEKALLRRLVEAGTRVVQYGYagAEGAD 151 
224988441  72 LYGRGEPADAVTVAAELDRRGLLRRIGGAPYLHTLISTVPTAANAGYYASIVAEKALLRRLVEAGTRVVQYGYagAEGAD 151 
54027550   73 LYGRGEPADPVTVAAGLDRRGELKRIGGAPYLVTLTQTVPTAANAGYYAEIVAEKAILRRLVEAGTRIVQYGYagADGQD 152 
152968276  90 LYSRGEPADPVTVSAELTNKGELTRIGGTPYLHDLISTVPTAANAAFYARIVRERAVLRRLVEAGTRIVQMGYg-ADGMD 168 
268315593 173 AFELLDEVEAEIFRLSDVHLRKAARSMNEVVKETLERLEAIHGRPGGITGVPSGFHQLDALTGGWQRGDLIIIAARPSMG 252 
291296959 137 LEDILDTAGRKVLEVSTQGARSEFQSMKELVHETFEHIQMLYENKGQVDGVKSGFRELDSMIGGLTSGSLNIIAARPSMG 216 
16331718  134 LETIFDESEQKIFRLTQSRPQAGLVPLSETLVNTFIELDKLHEKLS-SPGVETQFYDLDAMTGGLQRADLIILAGRPSMG 212 
148821248 152 VAEVVDRAQAEIYDVADRRLSEDFVALEDLLQPTMDEIDAIASSGGLARGVATGFTELDEVTNGLHPGQMVIVAARPGVG 231 
148659818 152 VAEVVDRAQAEIYDVADRRLSEDFVALEDLLQPTMDEIDAIASSGGLARGVATGFTELDEVTNGLHPGQMVIVAARPGVG 231 
253796973 152 VAEVVDRAQAEIYDVADRRLSEDFVALEDLLQPTMDEIDAIASSGGLARGVATGFTELDEVTNGLHPGQMVIVAARPGVG 231 
121635968 152 VAEVVDRAQAEIYDVADRRLSEDFVALEDLLQPTMDEIDAIASSGGLARGVATGFTELDEVTNGLHPGQMVIVAARPGVG 231 
224988441 152 VAEVVDRAQAEIYDVADRRLSEDFVALEDLLQPTMDEIDAIASSGGLARGVATGFTELDEVTNGLHPGQMVIVAARPGVG 231 
54027550  153 IAEVVDRAQAEVYEVTERRTTEDFLPLEELLQPTMDEIDSIASRGGISLGVPTGFSELDELTNGLHPGQMIIVAARPGVG 232 
152968276 169 VDAIVNSAQAEVYAVTETRTKEDYAVLGDVIEGTIDEIEASSHRGEGMVGVPTGFADLDSLTNGLHPGQMIVIAARPAVG 248 
268315593 253 KTAFALSCARNAALHpHYgTGVAIFSLEMGAEQLAQRLLTAEARVDAQAARTGRLRDEDWRKLARAAGRLSDAPIFIDDT 332 
291296959 217 KTSFALTIAQNVALR-GEgAAVAIFSLEMPAVQLVTRMLCSEARIDMNRLRQGQLTDRDFSRLVDVAGRISEAAILIDDT 295 
16331718  213 KTAFGLGIAANIAKN-QN-LPVAIFSLEMSKEQLALRLVASESLIDSNRLRTGHFSQAEFEPLTAAMGTLSSLPIYIDDT 290 
148821248 232 KSTLGLDFMRSCSIR-HR-MASVIFSLEMSKSEIVMRLLSAEAKIKLSDMRSGRMSDDDWTRLARRMSEISEAPLFIDDS 309 
148659818 232 KSTLGLDFMRSCSIR-HR-MASVIFSLEMSKSEIVMRLLSAEAKIKLSDMRSGRMSDDDWTRLARRMSEISEAPLFIDDS 309 
253796973 232 KSTLGLDFMRSCSIR-HR-MASVIFSLEMSKSEIVMRLLSAEAKIKLSDMRSGRMSDDDWTRLARRMSEISEAPLFIDDS 309 
121635968 232 KSTLGLDFMRSCSIR-HR-MASVIFSLEMSKSEIVMRLLSAEAKIKLSDMRSGRMSDDDWTRLARRMSEISEAPLFIDDS 309 
224988441 232 KSTLGLDFMRSCSIR-HR-MASVIFSLEMSKSEIVMRLLSAEAKIKLSDMRSGRMSDDDWTRLARRMSEISEAPLFIDDS 309 
54027550  233 KSTLGMDFMRSCSIK-HG-LASVIFSLEMSRTEIVMRLLSAEAKIKLADMRSGRMSDDDWTKLARRMSEISEAPLFVDDS 310 
152968276 249 KSTLGLDIARAASIK-HG-LASVIFSLEMGRNEIAMRLLSAEARVPLQKMRKGNMDDADWTRFARTMGAINEAPLYIDDS 326 
268315593 333 PSLGVLELRAKCRRLKAEH--DIGLVIVDYLQLMQASh--mPRNANREQEIAQISRSLKALAKELNVPVVALSQLSRAVE 408 
291296959 296 SDLTLMELRARARRLHAQH--RLGLIVIDYLQLMSGPgggkNGGENRQQEIAQISRGLKGLARELDVPVIALSQLSRAVE 373 
16331718  291 ASISVTQMRSQVRRLQSEQkgPLGMVLIDYLQLMEGG------SDNRVQELSKITRSLKGLAREINAPVIALSQLSRAVE 364 
148821248 310 PNLTMMEIRAKARRLRQKA--NLKLIVVDYLQLMTSG----KKYESRQVEVSEFSRHLKLLAKELEVPVVAISQLNRGPE 383 
148659818 310 PNLTMMEIRAKARRLRQKA--NLKLIVVDYLQLMTSG----KKYESRQVEVSEFSRHLKLLAKELEVPVVAISQLNRGPE 383 
253796973 310 PNLTMMEIRAKARRLRQKA--NLKLIVVDYLQLMTSG----KKYESRQVEVSEFSRHLKLLAKELEVPVVAISQLNRGPE 383 
121635968 310 PNLTMMEIRAKARRLRQKA--NLKLIVVDYLQLMTSG----KKYESRQVEVSEFSRHLKLLAKELEVPVVAISQLNRGPE 383 
224988441 310 PNLTMMEIRAKARRLRQKA--NLKLIVVDYLQLMTSG----KKYESRQVEVSEFSRHLKLLAKELEVPVVAISQLNRGPE 383 
54027550  311 PNLTMMEIRAKARRLKQRH--DLKLVVVDYLQLMTSG----KKVESRQQEVSDFSRNLKLLAKELEVPVVAISQLNRGPE 384 
152968276 327 PNMSLMEIRSKCRRLKQRA--DLKLVIVDYLQLMTSG----KRVESRQQEVSEFSRALKLLAKEIEVPVIALSQLNRGPE 400 
268315593 409 TRgGDKRPQLSDLRESGCLAGDTLITLAD-GRRVPIRELV--SQQNFSVWALNPQTYRLERARVSRAFCTGIKPVYRLTT 485 
291296959 374 SR-PNKRPMLSDLRESGCLTGDSLVQMAD-GSRQPIRGLV--GKSGFAVLALDEATQKLVPARVSRAFSTGVKPVFTLTT 449 
16331718  365 SR-TNKRPMMSDLRESGCISGDSLISLAStGKRVSIKDLL--DEKDFEIWAINEQTMKLESAKVSRVFCTGKKLVYILKT 441 
148821248 384 QR-TDKKPMLADLRESGCLTASTRILRADtGAEVAFGELMrsGERPM-VWSLDER-LRMVARPMINVFPSGRKEVFRLRL 460 
148659818 384 QR-TDKKPMLADLRESGCLTASTRILRADtGAEVAFGELMrsGERPM-VWSLDER-LRMVARPMINVFPSGRKEVFRLRL 460 
253796973 384 QR-TDKKPMLADLRESGCLTASTRILRADtGAEVAFGELMrsGERPM-VWSLDER-LRMVARPMINVFPSGRKEVFRLRL 460 
121635968 384 QR-TDKKPMLADLRESGCLTASTRILRADtGAEVAFGELMrsGERPM-VWSLDER-LRMVARPMINVFPSGRKEVFRLRL 460 
224988441 384 QR-TDKKPMLADLRESGCLTASTRILRADtGAEVAFGELMrsGERPM-VWSLDER-LRMVARPMINVFPSGRKEVFRLRL 460 
54027550  385 QR-TDKRPMVSDLRESGCLPASTRILRADtGAESTLGELLasGEQPL-VWSLDER-MRMVARPMVKVFPSGRKEVFRLRL 461 
152968276 401 QR-TDKRPMVSDLRESGCLTAGTRVLRADtGAETTMGELFalQARDVPVWSLDES-LRYVRRHLTRVFPTGVKPVFRLRT 478 
268315593 486 RLGRSIRATANHRFLTPQGWKRVDELQPGDYLALPRRIPTA-STPTLTEAELALLGHLIGDGCTLPHHVIQYTSRD-ADL 563 
291296959 450 RLGRSIRATANHKFLTARGWKRLDELTVGDYLALPRRLASP-QQQSLGDEELALLGHLIGDGCTLPRHSLQYTTRD-PDL 527 
16331718  442 RLGRTIKATANHRFLTIDGWKRLDELSLKEHIALPRKLESS-SLQLMSDEELGLLGHLIGDGCTLPRHAIQYTSNK-IEL 519 
148821248 461 ASGREVEATGSHPFMKFEGWTPLAQLKVGDRIAAPRRVPEPiDTQRMPESELISLARMIGDGSCLKNQPIRYEPVDeANL 540 
148659818 461 ASGREVEATGSHPFMKFEGWTPLAQLKVGDRIAAPRRVPEPiDTQRMPESELISLARMIGDGSCLKNQPIRYEPVDeANL 540 
253796973 461 ASGREVEATGSHPFMKFEGWTPLAQLKVGDRIAAPRRVPEPiDTQRMPESELISLARMIGDGSCLKNQPIRYEPVDeANL 540 
121635968 461 ASGREVEATGSHPFMKFEGWTPLAQLKVGDRIAAPRRVPEPiDTQRMPESELISLARMIGDGSCLKNQPIRYEPVDeANL 540 
224988441 461 ASGREVEATGSHPFMKFEGWTPLAQLKVGDRIAAPRRVPEPiDTQRMPESELISLARMIGDGSCLKNQPIRYEPVDeANL 540 
54027550  462 ASGREVEATGNHPFLTVDGWIPLDRLTVGDRLATPRSVPEPvHTERMADAEVVLLAHMIGDGSCVRRQPVRYASIDeQNL 541 
152968276 479 ASGKTVRATANHPFLTYDGWKPLGELSVADRLAVPRHVPAPeRVASWTDDQVLLLGHLIGDGSFVKRQPLRYASVDeANL 558 
268315593 564 ATLVAHLATK-----VFGSKVTPQIRKELRWYQVYLRAARPLAPGKRNPISDWLRDLGIFGLRSYEKKVPALLFCQTSEA 638 
291296959 528 AQTVVDLARV-----VFGESIAPKIKSERGWLQVYLSAAHRLGWGKRNPVAVWLEGLGVWGLRSHEKRIPRQVFAQPAPA 602 
16331718  520 AEKVVELAKA-----VFGDQINPRISQERQWYQVYIPASYRLTHNKKNPITKWLENLDVFGLRSYEKFVPNQVFEQPQRA 594 
148821248 541 AAVTVSAAHSdg-aaIRDDYLAARVPSLR-------PARQRLPRGRCTPIAAWLAGLGLFTKRSHEKCVPEAVFRAPNDQ 612 
148659818 541 AAVTVSAAHSdr-aaIRDDYLAARVPSLR-------PARQRLPRGRCTPIAAWLAGLGLFTKRSHEKCVPEAVFRAPNDQ 612 
253796973 541 AAVTVSAAHSdg-aaIRDDYLAARVPSLR-------PARQRLPRGRCTPIAAWLAGLGLFTKRSHEKCVPEAVFRAPNDQ 612 
121635968 541 AAVTVSAAHSdg-aaIRDDYLAARVPSLR-------PARQRLPRGRCTPIAAWLAGLGLFTKRSHEKCVPEAVFRAPNDQ 612 
224988441 541 AAVTVSAAHSdg-aaIRDDYLAARVPSLR-------PARQRLPRGRCTPIAAWLAGLGLFTKRSHEKCVPEAVFRAPNDQ 612 
54027550  542 AAVSEAAEHFgv-taVRDDYAAARVTTLR------LPAPYRLSRGKRNPIAAWLDELGLFGLRSHEKFIPRRVFALPNDQ 614 
152968276 559 SAVTEAAANAfsivaVRDEYAAARCTTLR------LPAPYRLTHGRRNPLAAWLDELGLFGLRSYEKFVPQEVFHLPKRQ 632 
268315593 639 IATFLRHLWATDGCIQMRRGKKPYPAVYYATSSYQLARDVQSLLLRLGINARLKTVAQGEKGRVQYHVKVSGREDLLRFV 718 
291296959 603 VARFLRHLWSTDGCVALRQGKAPYPAVYYASSSEGLAQDVQTLLLYLGINARLKRVPQKGKGRDQFHVVLSGQSDLLRFV 682 
16331718  595 IAIFLRHLWSTDGCVKLIVEKSSRPVAYYATSSEKLAKDVQSLLLKLGINARLSKISQNGKGRDNYHVTITGQADLQIFV 674 
148821248 613 VALFLRHLWSAGGSVRW-DPTNGQGRVYYGSTSRRLIDDVAQLLLRVGIFSWITHAPKLG-GHDSWRLHIHGAKDQVRFL 690 
148659818 613 VALFLRHLWSAGGSVRW-DPTNGQGRVYYGSTSRRLIDDVAQLLLRVGIFSWITHAPKLG-GHDSWRLHIHGAKDQVRFL 690 
253796973 613 VALFLRHLWSAGGSVRW-DPTNGQGRVYYGSTSRRLIDDVAQLLLRVGIFSWITHAPKLG-GHDSWRLHIHGAKDQVRFL 690 
121635968 613 VALFLRHLWSAGGSVRW-DPTNGQGRVYYGSTSRRLIDDVAQLLLRVGIFSWITHAPKLG-GHDSWRLHIHGAKDQVRFL 690 
224988441 613 VALFLRHLWSAGGSVRW-DPTNGQGRVYYGSTSRRLIDDVAQLLLRVGIFSWITHAPKLG-GHDSWRLHIHGAKDQVRFL 690 
54027550  615 VALFLRHLWATDGSVRW-DSTYRQARVYYTSTSRRLIDDVAQLLLRLGVHGRIRRVTKPG-YRDAWHLTIDGADNQTVFL 692 
152968276 633 IALFLRHLWATDGSVTL-TRQSRGGRIYYASTSLQLIQDVSRLLLRFGISTRVRTTTPKGDHRPGYTLDVSGVDDQRRFL 711 
268315593 719 EKIGAVGARQRAALASVYDYLSVRTGNPNRDIIPVALWYELVREAMYQRGISHRQLHANLGMAYGGMTLFRQNLSRARAL 798 
291296959 683 REVGAVGRSKQSALAVVEAYLTGRQENTNRDVIPLELWLQPARASLAVIGMSHRELHRALGMAYSGATLFGQNLSRERTR 762 
16331718  675 DQIGAVDKDKQASVEEIKTHIAQHQANTNRDVIPKQIWKTYVLPQIQIKGITTRDLQMRLGNAYCGTALYKHNLSRERAA 754 
148821248 691 RHVGVHGAEAVAAQEMLRQ-LKGPVRNPNLDSAPKKVWAQ-VRNRLSAKQMMDIQLHEP--------TMWKHSPSRSRPH 760 
148659818 691 RHVGVHGAEAVAAQEMLRQ-LKGPVRNPNLDSAPKKVWAQ-VRNRLSAKQMMDIQLHEP--------TMWKHSPSRSRPH 760 
253796973 691 RHVGVHGAEAVAAQEMLRQ-LKGPVRNPNLDSAPKKVWAQ-VRNRLSAKQMMDIQLHEP--------TMWKHSPSRSRPH 760 
121635968 691 RHVGVHGAEAVAAQEMLRQ-LKGPVRNPNLDSAPKKVWAQ-VRNRLSAKQMMDIQLHEP--------TMWKHSPSRSRPH 760 
224988441 691 RHVGVHGAEAVAAQEMLRQ-LKGPVRNPNLDSAPKKVWAQ-VRNRLSAKQMMDIQLHEP--------TMWKHSPSRSRPH 760 
54027550  693 RDVGVHGARGDAAQVALAE-LEPLVRNTNVDTVPNEVWNQ-VRHLLATKNITHREFSAAMGSRFCGSTMWKRSPSRSRLA 770 
152968276 712 QEIGVHGARGATADRLLEV-IRDVSANTNVDTVPRQVWDD-VRRLLVEKEMTHREFAAAMGTSFGGSSLWKHAPSRERLG 789 
268315593 799 RLAEAAACPELRQLAQSDVYWDPIVSIEPDGVEEVFDLTVPGPHNFVANDIIAHNSIEQDADVVLFIYRPERYgitvdEN 878 
291296959 763 RMAGALGSEALERLADSDIYWDTVRSIEAAGQEEVFDLTVPGPHNFIANNIIVHNSIEQDADLVMFIYRDEYY-----NP 837 
16331718  755 KIATITQSPEIEKLSQSDIYWDSIVSITETGVEEVFDLTVPGPHNFVANDIIVHNSIEQDADLIMMIYRDEYY-----NP 829 
148821248 761 RAEARIEDRAIHELARGDAYWDTVVEITSIGDQHVFDGTVSGTHNFVANGISLHNSLEQDADVVILLHRPDAF-----DR 835 
148659818 761 RAEARIEDRAIHELARGDAYWDTVVEITSIGDQHVFDGTVSGTHNFVANGISLHNSLEQDADVVILLHRPDAF-----DR 835 
253796973 761 RAEARIEDRAIHELARGDAYWDTVVEITSIGDQHVFDGTVSGTHNFVANGISLHNSLEQDADVVILLHRPDAF-----DR 835 
121635968 761 RAEARIEDRAIHELARGDAYWDTVVEITSIGDQHVFDGTVSGTHNFVANGISLHNSLEQDADVVILLHRPDAF-----DR 835 
224988441 761 RAEARIEDRAIHELARGDAYWDTVVEITSIGDQHVFDGTVSGTHNFVANGISLHNSLEQDADVVILLHRPDAF-----DR 835 
54027550  771 RVAAVLDDADIEMYATNDVFWDKIVEITSLGEQDVYDGTVPGTHNFVAQSISVHNSLEQDADMVILLHRPDAF-----ER 845 
152968276 790 RVAQVLDSAELDVLAVNDVLWDEVVAIEPDGEEQVYDATVLGGHNFVADGIAVHNSIEQDADMVILLHREDMY-----EK 864 
268315593 879 GNPTEGIAEIIIGKQRNGPTGTVRLAFINQYARFENLTMY 918 
291296959 838 HSEKAGIAEIIVGKQRNGPTGTVELQFHAQHVRFNDLAKD 877 
16331718  830 DTPDPGVAELLIVKHRNGPTGVVKLLFKPEFTQFLNLQRS 869 
148821248 836 DDPRGGEADFILAKHRNGPTKTVTVAHQLHLSRFANMAR- 874 
148659818 836 DDPRGGEADFILAKHRNGPTKTVTVAHQLHLSRFANMAR- 874 
253796973 836 DDPRGGEADFILAKHRNGPTKTVTVAHQLHLSRFANMAR- 874 
121635968 836 DDPRGGEADFILAKHRNGPTKTVTVAHQLHLSRFANMAR- 874 
224988441 836 DDPRGGEADFILAKHRNGPTKTVTVAHQLHLSRFANMAR- 874 
54027550  846 DDPRGGEADLIVGKHRNGPTATITVAHQLHLSRFVDMARG 885 
152968276 865 ESPRAGEADFIVAKHRNGPTDTITVAFQGHYSRFVDMAT- 903 
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap