Conserved Protein Domain Family
PRK06278

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PRK06278: PRK06278 
cobyrinic acid a,c-diamide synthase; Validated
Statistics
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PSSM-Id: 180505
Aligned: 16 rows
Threshold Bit Score: 658.265
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
148643314   2 KKIGLVYIKGAVPGFENFGELPTHLVKSNGlvdgKKASNELDALIIPGGTLLESGDI--SDDLSKEIKQIakdGKPIIGV 79 
297619926   1 MEIGLLSVKNTLPFFENFGNLPTKLISESN----IKDINDLDFFIIPGGSLIECNDLlnNNEFTSTMSNY---QGYILGI 73 
134046679   1 MEIGLIDIKGTLPCFENFGNLPTKIIRENN----ISEIKDLEMLIIPGGSIVESGSF--TDDFKKQILDF---DNYIVGI 71 
150401566  10 MEIGILDIKGALPCFENFGNLPTKIIDENN----VKIINDLDMLIMPGGSLVESGSL--TDDLKKQIIEF---DNIILGI 80 
15679494    4 MRIGLVCIRGSVPAFENFGFLPTDIVGSNGlvngSRAHRVLDGIIIPGGSIVESGSL--SPELAFEIRRMasdGKFVLGI 81 
304313858   1 MRIGLAYLRGSVPAFEDFGFLPTDLVKENGlvngERAHRVLDGIIIPGGSIVESGSL--SEDLGSEIRKMaaeGKFVLGI 78 
289192054   1 MEIGILDIKGSLPLFEDFGNLPTKIIDEKN----YKEIKDLDVLIIPGGSLVESKSL--NEGIKNEILNF---AGYIIGI 71 
15668308    1 MEIGILDIKGSLPLFEDFGNLPTKIITENN----YKEIKDLDALIIPGGSLIESKSL--NDDLKKEIINF---NGYIIGI 71 
296108836   1 MEIGILDIKSSLPCFETFGYLPTKIVDENN----LNEIKNLDALIIPGGSLIERGVN------LEVIREF---DGYIIGI 67 
261402423   1 MEIGILDIKGSLPLFEDFGDLPTKIIDEKN----FKEIKDLDCLIIPGGSLIESKSL--TNELKNEILNF---DGHIIGI 71 
148643314  80 CAGLQLLANQTDIGRKSEVPIIKEGLGLIDVNLSPLISSDRVNAKVYDNSFITKg-QNEDV------------TGFHTHT 146
297619926  74 CSGFQLLSYNIDIGRKSQTPILKKGLGLLDVNIAPLICTDRVNFKIEDKTLFNTlyKSDKNnnvlknnynklyEGFHCHT 153
134046679  72 CSGFQILSEKIDIGRKSPVPIVKEGLGLLNVEFSPLICTDLVKFNFENNNLFGE--KHQFG------------NGFHCHT 137
150401566  81 CSGFQILCEKIDIGRKSPVPIVKEGLNLLGVEFSPLICTDRVKFNIVESEIF----ENNSG------------TGFHCHT 144
15679494   82 CSGFQALAERTDIGRKSPCPVYREGLGLLNVTFHPMISNDRVEATITGESFLTSgmSGERI------------TGFHCHT 149
304313858  79 CSGFQALAERTDIGRKSPCPIYREGLGLLNVSFHPMISNDRVEALVTGESFLTSglTGERV------------TGFHCHT 146
289192054  72 CSGFQILSKKIDIGRKSSVPIIREGLGLLDVEFYPLVCTDRVEFKLKK-SIF----GEGRG------------EGFHCHT 134
15668308   72 CSGFQILAKKIDIGRKSSVPIIKEGLGLLDVEFSPLVCTDRVEFEVKK-SIF----GEGKG------------EGFHCHT 134
296108836  68 CSGFQILGERIDIGRKSEKPKIVEGLGLLEVEFSPLVCTDWVKFKAFDN---------IEG------------EGFHCHT 126
261402423  72 CSGFQILSNKIDIGRKSNVPIIKEGLGLLDVNFSPLVCTDRVEFNLKK-SIF----GEGVG------------FGFHCHT 134
148643314 147 YGKIE---GDAKPLFYSKIQRMNYGDVnkkSEYNIFSGACndDGNVIGTMIHNILDeNPIIRNNLLNYIDASSEDIEYIF 223
297619926 154 YGHITp--ENSKVFTKSIVNKLNYKMLe--TSNELISGAY--DGKIYGTMIHNFLD-NKNIKESLLSKFKIKEDELKEIT 226
134046679 138 YGNIEinnNSTEKWTTSEIEKLNYKMV---GKQNILSGVF--KNKVYGTMVHNLLD-NNFVVENFLKNMNIKEEEMEEIF 211
150401566 145 YGDIKitnKKTKPLTYSSIQKLNYKMT---GGKDILSGVY--CNNIIGTMVHNFLD-NKNIRENLFNYLKIDEIEQNNIF 218
15679494  150 YGEIR---GDAPEIMKSRIVRADYHE----RPGEILSGVCsdDGNVAGTMVHGCLDeNQTLVSNILKFLDADETARERIL 222
304313858 147 YGEIR---GDAPEIMRSIIRRADYRD----RRLEVTSGVCsdDGNVAGTMVHGALDeNPALVENILEFLGAGEDARERIM 219
289192054 135 YGDIRivdKETKILTVSKVKKLNYKLG---KEQEIISGAF--KDKVFGTMVHNFLD-NEFVRDNFLKHLGVAEDEKEEIF 208
15668308  135 YGNIEvvdKETKILTVSKVKKLNYKLG---AEKEIISGAF--KGKVFGTMVHNFLD-NEFVRDNFLKHLGVTEDEKEEIF 208
296108836 127 YGDVKi-yGKTKVLTVSKVKKLNYKF----EEKEIISGAY--KNKVFGTLVHRFLD-NREVRDKFFEIFKVSEEEKEEIF 198
261402423 135 YGNIEifnKRTKILTTSIVKKIDYKVG---LSKEIISGAF--KGKIFGTMVHNFLD-NKFVRDNFLKHLKISDDEKEKIF 208
148643314 224 AKNKEVKSKINMEV--------GIDSGHKIEKLSGeflkyknngkgPKFLMIGSNGSDSGKTFILTGLAGALRKRglkVA 295
297619926 227 DKNQKIKLNSKKYRfngktdinKIDNIKKAK----------------KGIILLGTGSESGKTFITTSIAGKLAEKgykVF 290
134046679 212 KKNSILKEKLKNRS--------KISENFKNESNDK------------KGIILLATGSESGKTFLSTSICSKLKGK---TF 268
150401566 219 KKNKEIKNKLKAKSiiynnkykNENNNNKNTNDNKnl-------nsKKGLILLATGSDSGKTFLITSIVSKLNKK---TF 288
15679494  223 EANRKLREALRSEL--------GISTGIRVMDRGGtr-------gtPPAIMIASTGSDSGKTFILTGLAGALRRRglrVG 287
304313858 220 EKNRELRKTLRSEI--------GVGTGINVEERGSetr------ntPPAIMIASTGSDAGKTFIVTGLAGALRKRglrVG 285
289192054 209 EKNKIIKDELKKRAlkyrlnpeLIENNKKDKNKK-------------RGIILLATSSNSGKTFLTTAISAKLKGR---VF 272
15668308  209 EKNKIIKDELKKRAlkyrlnpkLLKENNKKDVNKK------------RGIILLATSSNSGKTFLTTALSSKLNGR---VF 273
296108836 199 KKNKILREELRKRAlaykeykeSLGK---------------------RGVVLLGTSSNAGKTLLTTSLTYHLDGK---VF 254
261402423 209 EKNRKIKKELKIRSlknqltseINISKNINNTKNRnlergknklnnMKGIVLLSTSSNSGKTFLTTALSAKLKGK---IF 285
148643314 296 LMKVGPDARDIVPGLYLTNGKMEDYGSIKIGHLGWMDIKLAIDKLNKSDYDIVLIEGVMSVFTGLLNEKVpYSASEIAMS 375
297619926 291 SAKIGPDVRDIVPSLYITNETMTKYNSIKIYDRGWSTISEFKKYIETSDYDYYIIEGVMGAFTGCLNKAG-YSSAEIAKF 369
134046679 269 FSKIGPDVRDIVPSLYLLREPMTKFSSIKISDRGWSEPSEFLEFVKNSEYNNYIIEGVMGAFTGALNKKN-YSGSEVSKI 347
150401566 289 VAKIGPDVRDIVPSLYILREEMTKYNSIKIADRGWCEVEEFMNFVNNSDYEYYIIEGVMGAFTGALNKKN-YSGAEISKT 367
15679494  288 VIKVGPDVRDIVPALYLIKEPMEEHSSIRIGRLGWMELRDVLESVRGR-YDIILIEGVMSILTGLLNDITpYSGAEIALA 366
304313858 286 VMKVGPDVRDIVPALYLIKEPMEEHSSIRIGHLGWMDLEDALESVRGR-YDIILIEGVMSILTGLLNETVpYSGAEIALA 364
289192054 273 VTKIGGDVRDIVPALYLLREKMTKYNSIKIGERGWVDVKEFLEYIKKADYDYIIVEGVMGAFTASLKNISsY---QIAKK 349
15668308  274 VAKIGGDVRDIVPALYLLREKMTKYNSIKIGERGWVDVSKFLDYIKKSDYDYIIVEGVMGAFTAALKNISsY---QIAKK 350
296108836 255 VAKIGGDVRDIVPSLYLLREEMSKYNSIEIGGRGWCSVEEFKEFVKNSKYNYYIVEGVMGVLTGALKNISsY---QVAKK 331
261402423 286 VAKIGGDVRDIVPSLYLLREKMTKYNSIKIGNRGWVDVEEFLNHVKRENYNYVIIEGVMGAFTASFKNMSsY---QIVKK 362
148643314 376 SDIPMLLMSGVNKGGIESAAVDLVAHANMLKKL-GVTVEAILLNKVYNQNIFENVVPYIKNntQVKNVLNVSKLKI---- 450
297619926 370 LNIPTYVVSSCSKSGIEGAYIESLIYYKLLEKI-GADVKGIILNKTYNDRIAEKVKKIGDL--SDIDIIPIKKAKQnini 446
134046679 348 LGFPVYIISSCSKTGIEGSFVECMAYYSLLKEM-GINVAGIILNRVYNKEVFEKVKKIADD--LNINVIGVNKLNVnv-d 423
150401566 368 LGAPTYIVSACNKSGIEGAFVESLAYYSLLKEM-GVNVKGMILNKIYNFEIFEKVKEIGEN--IGLEVIGVGKAIQ---- 440
15679494  367 AGIPLIMVAGCSKGGIESAVVDLDAHISVLEGL-GLEVSCGILNRVYDMDIFERA--------SGGRYLAIPRVEM---- 433
304313858 365 AGIPVIMVAGCSRGGVESAAVDLEAHISVLERL-GVEVPHAILNRVYDMDIFERA--------SGGRYLSLPRVRM---- 431
289192054 350 LGFPVYIVSPCNISGIEGAFVEAMAYYSLLKDI-GIKVEGIILNKVYSWEGFNKLKSLAEK--YNIKLYGVGKVAN---- 422
15668308  351 LGFPVYIVSACNISGIEGAFVEAMAYYSLLKDI-GIKVEGVILNKVYDWNSFNKLKSLAEK--HNIKLYGVGKIAN---- 423
296108836 332 LGFPVYIIASCNLSGIEGAFLESLIYKKFLEEN-GVKVEGIILNKVYNFELFEKIKKLAEK--YNIKVCGVKKLGE---- 404
261402423 363 LGFPVYIVSACNLSGMEGAFVEAVSYYHLLKKIgGVKVEGIILNKIYDLEIFNALKNLAKK--YGIKLYGVKKVNK---- 436
148643314 451 DGRGFTPEVEIRYDLFSKYALEcVEENIDINTIASMAKNVNFNR-----------IVPFEEIKNKVI 506
297619926 447 KNRGLMPEIEIDYDLFCKLALE-LDINMDLFNMTINNKNNLNDEiiqkyfensddTTYLEQKIQELS 512
134046679 424 NKRGLIPEVEIDYEEFCNATMK-LDFEINIPKIDIGNVNEDHKS--------------FEEYIKIWS 475
150401566 441 NKRGLMPEVEIDYEEFCKNANN-ITMDINIPKLNINGHNNSNNSnt--------qNYDFKHYLEKWS 498
15679494  434 SERGGTPEVEIKLEDFCLKAMEtVEEHLDVDTLISFAKKPEFRG-----------YMGPEEIKKVFS 489
304313858 432 SMRGGTPEVEIKLEDFCMRAMEaVEENLDVDLLISEAAEPEFRG-----------YTDLEEIMRRFR 487
289192054 423 ESRGLIPEVEIDYESFCKNAFN-VNLEIEIPEIEINNNINDEDD-------------NFLDRVDNWI 475
15668308  424 ESRGLIPEVEIDYESFCRNAFN-VDLEIEIPEVEINNHIKDEED-------------NFLERLDNWM 476
296108836 405 EKRGLIPEVEIDYHEFCKKAKE-LNLKLEIPKISLREVEEEE----------------FLKELDKFM 454
261402423 437 EGRGLIPEVEIDYEEFCRSAFE-IDLDIEIPEIDFNIKQLDNKT--------------FIEELDLWM 488
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