Conserved Protein Domain Family
hemD

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PRK05928: hemD 
uroporphyrinogen-III synthase; Reviewed
Statistics
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PSSM-Id: 235647
Aligned: 232 rows
Threshold Bit Score: 116.605
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
56965173    6 GKHVALTA-SRKTEEMEALLHKQGATSAVRSLQGtviqdqetvteaiisglatqPDWFIFTTGIGVQTLLAFaeeagvke 84 
161349972   1 MNAAVFRPdDDRIADAVALLDDLGAVPVPDPMLAvdptga---------iprgdGAVVVVTSKTGVELAAD--------- 62 
169236889   1 ----MFRPdDDRIADAVALLDDLGAVPVPDPMLAvdptga---------iprgdGAVVVVTSKTGVELAAD--------- 58 
292654253   6 RAAVFRPD-DDRIERAVELLDSLGATPVPDPMLAieptg----------atpepGAFVVLTSKTGVELLDE--------- 65 
16081676    3 IFVLSIRP--------EEKAQRTGGACFDILNVPvtrlepipv--dytdlirsgVDCVAFTSSYGVRLFF---------- 62 
13541464    1 MTLRKFII-SLRPAEKFVKFDSPCFDLINIPVTRlmpldini----ekilkesaADCIVFTSTFGVDLFFSRvn------ 69 
222480663  10 RVAVFRPA-DERIEDAKALLASLGADPVADPMLAveptd----------atpedAPYVVLTSKTGVELAAE--------- 69 
76801316    3 SRVAFFRPdDERAVEAAVTVSELGAEPLSDPMLEveptgr---------tprddAAYTILTSKTGAELVA---------- 63 
110669323   1 ---------MVTAVEL---LEEYGITPIPDPMLSveptgtip----eidtvsdaSPFVVLTSKTGVEILAD--------- 55 
300713095   4 PTVAVLRPdDSRIVEAVEYLQTLDVSPIPDPMLAitptg----------qvpqhADYCIFTSETGVDLAATAgw------ 67 
56965173   85 aFIKQVRSARIAVRGYKAKNALLKENITMDVVSEDGTTAQLVEQLKEIdWNGQKVIVQQYGLPSPTLEQFLKEGKAMVSA 164
161349972  63 -SGWTPGGGRLAAIGPATADACREAGWTVDVVPEEYTSAGLVAALDGD-IDGARVEVARSDHGSAVLTDGLAEAGAYVHE 140
169236889  59 -SGWTPGGGRLAAIGPATADACREAGWTVDVVPEEYTSAGLVAALDGD-IDGARVEVARSDHGSAVLTDGLAEAGAYVHE 136
292654253  66 -AGWNPGDAVLCCIGPATADAARDAGWTVDRVPDEYTSAGLVDHLAPD-VDGATVEVARSDHGSAVLTDGLRDAGADVHE 143
16081676   63 -KNAPVKNFRYFGIGKSTCEEVRKYGYDCE-YPEKMDSEGLADMIISH-CSGRKVALIRSANANEIVNEKIMGH-VDFID 138
13541464   70 -----mkGFTILGIGKATCERVQAYGHKCLYPENMDSEGLANLIISKC--KDKKILILRSKKANEVLTEKLKEEGIDFLE 142
222480663  70 -AGWEPGDATLVAIGPATAEAARAAGWTVDLVPDEYTSAGLVAALEDR-VDGEHVEVARSDHGSDVLLAGLREAGATVTE 147
76801316   64 -DTGWQPGGELVAIGTATAGALEAAGFDVDRLPEEFSSSGIVSELEAD-APGTRIEVARSDHGSDVLTDGLVDAGGYVHE 141
110669323  56 -AGWNPTVATLVCIGPRTAAAARDVGWTVDIIPTEYSSQGLVDALADQ-VTDRSVIIARSDHGSETLIDGLDAAGAAVTE 133
300713095  68 ----kqRGTTVCAVGDQTATALCNRGYSVDIVPSTFTSTGLVDELSTD-VEGQIVELARSAHGSEVLVEGLEAAGAIVSE 142
56965173  165 WLPYIHYAPKGETIDLFleellekkeYDAVCFTTALQAKALFARASETGrheqllhmfagPTVACAVGKVTAEALSEEgv 244
161349972 141 TVLYALTRPAGAGDSTEiaa---agdLDAALFTSSLTVEHWLAAARERGiesaa-reglaDATVGAIGPPTAETAADHgi 216
169236889 137 TVLYALTRPAGAGDSTEiaa---agdLDAALFTSSLTVEHWLAAARERGiesaa-reglaDATVGAIGPPTAETAADHgi 212
292654253 144 TVLYRLVRPEGAGESAElaa---agdLEAALFTSSLTVEHFLDAAAERGireea-iaglnDAVVGAIGPPTRDTAESHgi 219
16081676  139 LRNYRAVNTNVDLTPYMak-----eeCMGIIVTSSMEAKIAMPAIKAT------------GKPVYSIGSVTTKTLEEAgi 201
13541464  143 FRIYDAVPDTKDFEKHYkd-----qnCLGVIITSSMEAEIVIPFLKED------------KKMVFSIGVTTTNTLMSHgi 205
222480663 148 TVLYRLTRPSDAGESAAmaa---agdLDAAAFTSSLTVTHFLDAAAERGvreaa-ieglnDAVVGVIGPPTAETAADSgi 223
76801316  142 TVLYRLVRPDGAGDSAVaaa---dgdLAGACFTSPLTVEYFLEAAADRGcrdaa-leglnTAVVGAIGDPTREAAAEHgi 217
110669323 134 TVLYKLVRPDGTGQSTVmaa---gneLDAVCFTSSLTVEHFLSAAANRElreet-imglnNAVVGTIGEPTRETAQAHgv 209
300713095 143 ICLYRLERPETAGQSVSlav---dgkLDGILFTSPKTVEHFVQIATERDavaal-qreleETIVGAIGAPTKRAVDKRgi 218
56965173  245 RRVIYPKKERMGAMIIELGKFL 266
161349972 217 SVDVVPDDAGFEALARATIEDA 238
169236889 213 SVDVVPDDAGFEALARATIEDA 234
292654253 220 DVTVVPDEATFEALAVAAVETA 241
16081676  202 HPAISGNSDFVDLVEKIKKYLC 223
13541464  206 MPDITGNSDFLELLKKIDYFIC 227
222480663 224 DVDVVPDDADFEALARAVADAV 245
76801316  218 EVDVVPGTAEFAALAEAVVDQL 239
110669323 210 RVDVTPADATFEHLVEAVVNEL 231
300713095 219 AVDVMPDTVGFTQLAEITVRRI 240
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