218884625  13 SYKVLSKphyLLGVYYDGRLGKAILEFLDEDGSKLVKIMDPvgHKPYFLTDLSIDEvksl----ndiARDKHVEGFEEVY 88 
55376565   27 ERDDYSP--------------------------------------RFYVASRAPDDeidltrlrsvyERHPDVVATDIVA 68 
16120259   27 ERDNYTP--------------------------------------RFYVAARDPDAdldlttlqsvyDQHPDVVATEMVA 68 
169237626  27 ERDNYTP--------------------------------------RFYVAARDPDAdldlttlqsvyDQHPDVVATEMVA 68 
169237743  26 ERRDYTP-------------------RFHVAARSPETDVDLsgLQAFY-------------------ERHPDVVATEYVD 67 
169237239  26 ERRDYTP-------------------RFHVAARSPETDVDLsgLQAFY-------------------ERHPDVVATEYVD 67 
292653630  28 ERDDYTP--------------------------------------RFYVAARDPETdldlttlqsvyDQHPDIVATEMVA 69 
13541876    1 --------------MYEYTGNNKIKKKRYRNSTWIFVSGDR-----YDLDNLARDL-------------DQSSLRYEWAE 48 
222476155  27 EHDDYTP--------------------------------------RFYVGPRSPDSdidltklrriyENHPDVVATEIVS 68 
300712715  31 RVTDYTP---TIYVTYDGRAEDGLSDLQERL------------------------------------ASSPTVASMAIEQ 71 

218884625  89 KTNPLTmkkirvtk-----iitrdplaVKKLRSKMPSN--A---SVWEAKIKYHNNYVYDNGLipgmkyiiendgskpri 158
55376565   69 QRPGFRrddedvlavdvahidritslaRQARQLSEYPVgdL---ACFNVDLSREFRYCLENDV----------------- 128
16120259   69 RRPGFRrdeeavlavdvahidrvtplaRQARQLSAYPVgdL---ACFNVDFSREFRYCLETGA----------------- 128
169237626  69 RRPGFRrdeeavlavdvahidrvtplaRQARQLSAYPVgdL---ACFNVDFSREFRYCLETGA----------------- 128
169237743  68 RHPGFRrdlervlavdvshidrvtalaRQTRQLSEYPIgdI---ACFNVDFSREFRYCLENNV----------------- 127
169237239  68 RHPGFRrdlervlavdvshidrvtalaRQTRQLSEYPIgdI---ACFNVDFSREFRYCLENNV----------------- 127
292653630  70 RRPGFRrdeepvlavdvahidrvtplaRQARQLSDYPIgdI---ACFNVDFSREFRYCLETGV----------------- 129
13541876   49 MPDVYGyilglki-------ytrpssaYRLGNLIYAKLgyGrrfRVYNADIDPVLRFMASNGLef--------------- 106
222476155  69 RRPGFRrdgeevlavdvthvnrvttlaPQARQLSEFPIgdL---ACFNVDFLREFRYCLENDI----------------- 128
300712715  72 WRQGFRhehesilr-----idvrelaaVRPLASQIRKLgwPgeyKLYNVDFSREFRYCLERG------------------ 128

218884625 159 tlvkpeipltliqslrelfknepeetiklaedyLLLFEEAPPKALRIAIDIEVYTPFkgrIPNprqgeypvisiglssnn 238
55376565  129 --------------------------------------DPTPTCDLSTLRLDV--------PLtettgdayte------- 155
16120259  129 --------------------------------------DPTPASELSTLRLSV--------PVtetsndiyee------- 155
169237626 129 --------------------------------------DPTPASELSTLRLSV--------PVtetsndiyee------- 155
169237743 128 --------------------------------------NPTPANELSTLHLSI--------PVtetnsktyte------- 154
169237239 128 --------------------------------------NPTPANELSTLHLSI--------PVtetnsktyte------- 154
292653630 130 --------------------------------------NPTPASELSSLRLSV--------PVtetsndvyge------- 156
13541876  107 -------------------------------fqLRTFYDEDPDLNVIYVSCTSSSCK----------------------- 132
222476155 129 --------------------------------------DPTPASELSTLRLSV--------PVtettgdayte------- 155
300712715 129 -------------------------------------RDPTPTRVPSVLAIDAEPPA---LSNppltelqineetvtgsp 168

218884625 239 gfrkvlllgrrfkerfdymsddypvdievevfDSEKALILEALKTISRYPVVLTYNGDnfdlmYIYTRAIRLGIPRHTIP 318
55376565  156 -----------------------lavggetvtGPPEDILTTVQAALDNHDPDVLVCSTseivpTLYEMAASTGADNFSLS 212
16120259  156 -----------------------lsvagdavtGSSTDILAAVQGALEAHDPDVLVCSTseivpTLHEMATDAGVDDFSLS 212
169237626 156 -----------------------lsvagdavtGSSTDILAAVQGALEAHDPDVLVCSTseivpTLHEMATDAGVDDFSLS 212
169237743 155 -----------------------lgvdgetvtGPPEELLAAVQDALDVRDPDVLVCSTseiipTLYAMARDAGVDGFTLS 211
169237239 155 -----------------------lgvdgetvtGPPEELLAAVQDALDVRDPDVLVCSTseiipTLYAMARDAGVDGFTLS 211
292653630 157 -----------------------lsvagdtvtGSPTEILTAVKAALEEHNPDVLVCSTseiipTLYEMTTDADVDDFSLS 213
13541876  133 --------------------------------VNGKAVNDQALEDMLFDSHVVVYDGPe----YFYRKLSMIGVPARYYP 176
222476155 156 -----------------------lsvdgetitGSTEDILTAVQAAVDERDPDILVCSTsqiipTLHEMATHAGVGNFSLS 212
300712715 169 ea------------ilyaiqrrlrqvdpdvlvlSSGELIPTLSEMADQHDVDLQLGRRpg-------------------- 216

218884625 319 FILGEdmvridtgihldlyKFFSNRAVKNYAFGGKYQ--EEKLDAVSSALLGISKigfeeaigdisashliaynmrdadi 396
55376565  213 RTPKG--------------DFQQLASRSTYASYGRVGhsPARYNVPGRAIIDRSN------------------------- 253
16120259  213 RWPDV--------------DYQQLASRSTYSSYGRVGhsPARYNVPGRAIIDESN------------------------- 253
169237626 213 RWPDV--------------DYQQLASRSTYSSYGRVGhsPARYNVPGRAIIDESN------------------------- 253
169237743 212 RWPNV--------------DYQQLAGRSTYSSYGRVGhsPARYNVPGRAIIDESN------------------------- 252
169237239 212 RWPNV--------------DYQQLAGRSTYSSYGRVGhsPARYNVPGRAIIDESN------------------------- 252
292653630 214 RWPDV--------------DYQQLASRSTYSSYGRVGhsPARYNVPGRAIIDESN------------------------- 254
13541876  177 G--------------------------RSFTSYGQIYfrDAYIDIQDRIAIPAS-------------------------- 204
222476155 213 RWPDV--------------DYQQLASQSTYSSYGRVGhsPARYNVPGRAIIDESN------------------------- 253
300712715 217 --------------------weRLAGRSTYESYGSVGhsPARYNVPGRVIIDRSN------------------------- 251

218884625 397 tlqlTIFSNELVWKLMILLARISKTSIEDVCRRQISNWIQNQFFWEHRRLGYLIPNSEDirryAGKAGTKATIEGKKYAG 476
55376565  254 ----TFFFGETNIDGVLDLVSRSRKPIQEAAWASIGNILTAIQICEAHDRGVLVPWHSW----RHEKFKSTGVLHDADRG 325
16120259  254 ----TFFYGETNLDGVLDLVSRSKNPVQELAWASIGNVLTAIQICEANDRGVLVPWNSW----RHEFYKPMGTLHDADRG 325
169237626 254 ----TFFYGETNLDGVLDLVSRSKNPVQELAWASIGNVLTAIQICEANDRGVLVPWNSW----RHEFYKPMGTLHDADRG 325
169237743 253 ----AFFFGETNLDGILDLVTRSKKPIQELAWASIGNVLTAIQICEAHKRGVLTPWNSW----RHEFYKPMTTLHDADRG 324
169237239 253 ----AFFFGETNLDGILDLVTRSKKPIQELAWASIGNVLTAIQICEAHKRGVLTPWNSW----RHEFYKPMTTLHDADRG 324
292653630 255 ----TFFYGETNLDGVLDLVSRSKKPVQELVWASIGNVLTAIQICEAHDRSVLVPWNSW----RHEFYKPMGTLHDADRG 326
13541876  205 ----SFLYSESGLSGIFEVSRVSYLNPVSVSIVTPGTAVSSMEVALAVNRGLLVPMKKD----DHEGQKSPEELIKRDRG 276
222476155 254 ----TFFYGETNLDGVLDLVSRSKKPVQELAWASIGNVLTAIQICEAHDRGILVPWNSW----RHEFYKPMGTLHDADRG 325
300712715 252 ----TFFHSQSGLDGCLDMVRRSGKPLQELGWASIGNVLTAMQIREARDREVLVPWNSW----RHEFFKPLSTLHDADRG 323

218884625 477 ALVIEPPRGIFFNVTVLDIASLYPSIIKKYNLSYETVDmpwckstidiidetgrklhvvcveKPGLTAQITGIL--RDFR 554
55376565  326 GFIFAPEVGLHEDVHELDFSSLYPNIICTHNVSPDVIRcechrdredv----pglgysicddRGYLVDVLQPIIdaRDEI 401
16120259  326 GFIFAPEVGLHENVHELDFSSLYPNIICTRNVSPDVIRcdchsdrddv----pglgysicddRGYLVDVLQPIIdaRDEI 401
169237626 326 GFIFAPEVGLHENVHELDFSSLYPNIICTRNVSPDVIRcdchsdrddv----pglgysicddRGYLVDVLQPIIdaRDEI 401
169237743 325 GFIFAPEVGLHEDVHELDFSSLYPNIICTRNVSPDVIRcdchsdrddv----pglgyaicddRGYLVDVLQPIIdaRDEI 400
169237239 325 GFIFAPEVGLHEDVHELDFSSLYPNIICTRNVSPDVIRcdchsdrddv----pglgyaicddRGYLVDVLQPIIdaRDEI 400
292653630 327 GFIFAPEVGLHENVHELDFSSLYPNIICTRNVSPDVIRcdchsgrddv----pglgysicddRGYLVDVLQPIIdaRDEI 402
13541876  277 GLVFQPVPGIYRDVYEIDFSSMYPSIIVKYNLSPGNVK--------------------------FLPEALNGLLerRLFY 330
222476155 326 GFIFAPEVGLHEDVHELDFSSLYPNIICTRNVSPDVIRcechrdrddv----pglgysicdeRGYLVDVLQPIIdaRDDI 401
300712715 324 GYTFSPEAGFHENVHELDFSSLYPNIICQFNVSPETIRcdchadradv----pgleysicdeRGYLPDVLQPLIdaRDTM 399

218884625 555 VGIYKKRAKDKTlpkdllawYDVVQRAIKVFINASYGVFGDERFSLFSPAVAESVTAMGRKSFLTIILKAAELGIKPLYG 634
55376565  402 KAAIRREQERDDpdkerldeLEGRSGALKWILVACFGYQGFNNAKYGRIECHEAINAFAREILLTAKQRLEAAGWRVVHG 481
16120259  402 KAAIRRETDRDDpdedrlaeLEGRSGALKWILVACFGYQGFSNAKFGRIECHEAINAFAREILLMAKQRLEAGGWRVVHG 481
169237626 402 KAAIRRETDRDDpdedrlaeLEGRSGALKWILVACFGYQGFSNAKFGRIECHEAINAFAREILLMAKQRLEAGGWRVVHG 481
169237743 401 KTAIRREEQRENpdqdcldeLEGRSAALKWILVACFGYQGFSNAKFGRIECHEAINAFAREILLIAKQRLEAGGWRVVHG 480
169237239 401 KTAIRREEQRENpdqdcldeLEGRSAALKWILVACFGYQGFSNAKFGRIECHEAINAFAREILLIAKQRLEAGGWRVVHG 480
292653630 403 KAAIRREKERNNpdedrlaeLEGRSGALKWILVACFGYQGFSNAKFGRIECHEAINAFAREILLTAKQRLEAGGWRVVHG 482
13541876  331 KRISASSe-----------vYSNRNAALKWLLLTSFGYTGYKNAKFGKIEVHEDITEIGRKLLADAISIAHDHGFEMIHG 399
222476155 402 KAAIRREQQRDEpdqarfaeLEGRSGALKWILVACFGYQGFSNAKFGRIECHEAINAFAREILLTAKQQLEASGWRVVHG 481
300712715 400 KREIREIDdeer-----vavLKSRADAIKWILVSCFGYQGFSNAKFGRIECHEAINAYAREILLDTKETFEANGWHLLHG 474

218884625 635 DTDSIFVWNpn------qSQLEMLQKWILENLGLEIELDkEFTYVVF-------TGLKKNYLGRM----KDG-GIEIKGL 696
55376565  482 IVDSIWVTPnpdvddedrESLEALATEITEAVDIRLEYEsHYDWVAFvpqresdAGALTKYFGKVv---DED-EFKIRGI 557
16120259  482 IVDSIWVTPdpdvdeedrEDLQTLATEITERVEIRLEHEaHYDWVAFvpqresdAGALTKYFGKVa---GDD-DFKVRGI 557
169237626 482 IVDSIWVTPdpdvdeedrEDLQTLATEITERVEIRLEHEaHYDWVAFvpqresdAGALTKYFGKVa---GDD-DFKVRGI 557
169237743 481 IVDSIWVTPdpdvsdderGSLETLAAEITDTVDIRLEYEaEYEWVAFvpqresdAGALTKYFGKV----AGKdEFKIRGI 556
169237239 481 IVDSIWVTPdpdvsdderGSLETLAAEITDTVDIRLEYEaEYEWVAFvpqresdAGALTKYFGKVa---GKD-EFKIRGI 556
292653630 483 IVDSIWVTPdpdiddddrEDLETLATEITERVEIRLEHEaHYDWVAFvpqresgAGALTKYFGKVa---GDD-EFKIRGI 558
13541876  400 IVDSLWISGn--------GDIEEVIREIRERTMVDIVVSgHYRWIVFlpe-ndgSGSPSRYYGLD----YNG-SYKVRGI 465
222476155 482 IVDSIWVTPdpdvddsqrEDLDVLAREITDRVEIRLEHEaHYDWVAFvpqrestAGALTKYFGKVa---GED-EFKLRGI 557
300712715 475 IVDSLWVTAieg---qkqTPLTELATVISDRVGIRLEYEsAFEWLALvplrdrdEGALTKYFGKVasatGDEpEYKYRGI 551

218884625 697 VAKKRNTPEFLKELFKEMLEKMKAIETPENFVVFVDWLREMLKEYYDGLKRKEIPldhlaiRVALTKPPSSYNKTKpPHV 776
55376565  558 EARQRSTPPFIEDVQRECLDRLDATQSPE-------AVLSCLDRAVSKLHAGEVAverlveRNRVSKPLDGYTQNT-QNV 629
16120259  558 EARQRSTPPFIEDVQRDCLDRLDATRSPD-------AVLGRLERAIDELQAGNVAverlveRNRVSKPLEGYSQNT-QNV 629
169237626 558 EARQRSTPPFIEDVQRDCLDRLDATRSPD-------AVLGRLERAIDELQAGNVAverlveRNRVSKPLEGYSQNT-QNV 629
169237743 557 EARQRSTPGFIEDVQRDCLEILGQTQSPD-------VVINRLERAISELHAGDVDsdrlveRNRVSKPVEAYTQYT-QNV 628
169237239 557 EARQRSTPGFIEDVQRDCLEILGQTQSPD-------VVINRLERAISELHAGDVDsdrlveRNRVSKPVEAYTQYT-QNV 628
292653630 559 EARQRSTPPFIEDVQRDCLNRLDATQSPD-------AVLGRLERAIKELHSGAVGveqlveRNRVSKPLEGYTQNT-QNV 630
13541876  466 ELRRADAPEICKRFQVEALEVLRECRTVEDVMSSKAKIEALEHRYIKNIRR--FPlnyftiSKKITRHSSEYSVNT--VT 541
222476155 558 EARQRSTPAFVEEIQRECLDRLDETRSPE-------AVLGYLERAIAELHAGDVAvdqlveRNRVSKPLEGYTQNT-LNV 629
300712715 552 ECRQRSTPDWITNAQQELIVTLDQSRSPE-------VVCARLQRQLAELHAGRVDpevltiDNRPSKHVEEYTRTT-RTV 623