Conserved Protein Domain Family
pdxA

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PRK03946: pdxA 
4-hydroxythreonine-4-phosphate dehydrogenase; Provisional
Statistics
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PSSM-Id: 179681
Aligned: 27 rows
Threshold Bit Score: 450.599
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
57238111    1 MKKLAISIGDINGIGLEILVRSHEELSKICTPFYFIHESLLDKASKLLNLKLFNakivafkdgkdyef-nfvkkenslei 79 
222823931   1 MKKIAISIGDLNGIGVQILLASHDELVKICEPYYFVHYKLFQKASKLLKLNTKSkinlveisyanepkfifkeekdnfli 80 
118475415   3 LPKIAISVGDINGVGIEIALKSHDEIKNICSPIYFINNELLNSAANILKFTVPN-------------------------- 56 
154148849   1 -MKLAISVGDINGVGIEIALKAHDEICKFCEPVYFINRELLNQAAEISGLNIPE-------------------------- 53 
34556558    1 -MKIFVSIGDPNGIGLEIALRSHSGVKDWGEIIYGVDERVLFEASQRLGIEVPQ-------------------------- 53 
157736900   5 LPKIAISIGDLNGIGIEIALKCHNQISKICQPIYCINNKMLTQASSLLKIRIPE-------------------------- 58 
296272462  11 KKKLAISIGDLNGIGLQIALEAHEKIKKYCSPVYCINKDLLKDGAKLLNLEIPK-------------------------- 64 
224373245   1 MQKVAVSIGDLNGVGIEIALKAHNIIKQWVNPVYCINEKILKQAAKLLNIPIPD-------------------------- 54 
78777093    3 KVRIAISVGDLNGVGIEIAIKAHEEVSKLCAPLYCINSYMLNQASTLLNYKIPS-------------------------- 56 
152993274   1 MKKVAISIGDLNGIGIQLALENHQVVSSIIDPVYCIDKEMLLQAAEKLNLPIPD-------------------------- 54 
57238111   80 ysfYLPLDFKVDENFEIKAGEIDTKSGLYGFLSFKAAsYFVYEKHAHALLTLPIHKKAWEDAGLKYKGHTDALRDFFKKN 159
222823931  81 ydfSYQTSKEIDYDFELNPANLDAKSGAYSFLSFEGA-SYCTHLFLDALVTLPINKKTWQMAGVSYKGHTEALREFFKQD 159
118475415  57 ---DFEIFE-CGSSFNIKPGRVSKKSGKFSFVSFENAiLYTQNKRAQALVTMPINKESWKKAGVPYVGHTDALGKYFGKN 132
154148849  54 ---NFKIYE-VGKNFKIKPGKVSKKSGKFSFLSFTKAvEQCKKGEFDAVCTLPINKEAWKKAGIKFVGHTDYLSVKFHKN 129
34556558   54 ---DMECDP-LGLESPIAPGVISKEAGRYSFESFKKGvERAKKGEVQAIVTLPVHKKAWSLAGIPYAGHTEALREMMGEE 129
157736900  59 ---NFELFK-TKGDFEIKPGTVSKKSGKYSFNSFMDAiNLANKKEVDAICTLPINKESWNKADIKYKGHTEVLRDYFGKH 134
296272462  65 ---DFELEK-VKGKFVIKPGTVAKDSGSYSFDSFTTAiKLASKKKVEAIVTLPINKESWNRAKIHYKGHTEVLRDYFGKD 140
224373245  55 ---DFVTFD-VEGDFKIKPGIVDADAGKYSFESFMTAiNLAKDKKVDAITTLPINKESWMRAGIKYKGHTEVLRDVFKKD 130
78777093   57 ---NFEISE-VGGEFAVKKGCVDKDSGRYSYDSFIHAiSLCEQKKADAVVTMPIHKEAWMLAGLKYKGHTDLLREHFKRD 132
152993274  55 ---NFHTHQTVAPAFEIEEGKVSRESGRYAYESFNKAvIMADLKKVDAICTLPIHKKAWELAGIHYKGHTDALRDFFDAE 131
57238111  160 AIMMLGCKELFVGLFSEHIPLAKVSKKITFKNLSIFLKDFYKETH-FKKMGLLGFNPHAGDYGVIGGEEEkIMEKAIAFV 238
222823931 160 AIMMLGCDELFVALYTEHIPLKDVYKQIKALRLAKFLIDFYQCTL-FEKIGVLAFNPHASDNGVIGGEEEnEIKKAIKMA 238
118475415 133 AIMMLGCEELFVALYTDHLALKDVSAKIKAKNLALFLVDFYNSSK-FENIGVLGFNPHASDNETIGGKEEkEIIKAIKSA 211
154148849 130 AIMMLGCDELFTALFTDHTALKKVSSMIKTEKFAKFLLNLYKCTK-FEKIGVLSFNPHASDNGVIGGSEEkKIKKAINKA 208
34556558  130 AIMMMGKEGFFIALYTDHLPLSEVPQRVHERGVEGFLRRLSHALPaMKACGVLGLNPHAGDQGVLGKEEE-GIKRAIERA 208
157736900 135 AIMMLGCEKMFVALFTEHIALKKVPKKINEEDLTKFLIDFYKNVK-SENIAVLGLNPHASDNGVLGDEEV-EIFKAIKKA 212
296272462 141 AIMMLGCSKMFVALYTEHIALRKVAKKIEEEKITKFLLDFYNNVK-QDNIAVLGLNPHASDNGVLGDEEV-EIIKAIKKA 218
224373245 131 AIMMLGCEEMYVALFTEHIPLKNVADRVKKDNLIKFFIDFHKSTN-FHKVGVLGLNPHAGDGGVLGDEEInEIIPAINEA 209
78777093  133 AIMMLGCQKMFVALFSEHIPLKDVASSIKYKKLKQFFLDFNNSVP-NERVAVLGLNPHAGDNGVLGNEEL-IITKAIKSA 210
152993274 132 AIMMLGCPEMYVALFTEHIPLKEVAPSIKEKALTRFLLDFYKTAKpDRTVAVLGLNPHAGDDGVLGDEEK-VITKAIKNA 210
57238111  239 NAFLH-----SKkdekffkkalkdenlqkelllNFKGkgvylphPLVADTAFTKTGLKNCNRLVAMYHDLALAPLKALYF 313
222823931 239 NVFLKdstlnLQnlenedflnqkekelsykeniFLSE-------PLVADSAFTPFALSKCKYLVSMYHDVGLAPLKALYF 311
118475415 212 NNRLK-----KE---------------------VFTG-------PLVPDAAFTKSSLKRCNRLVSMYHDVGLAPLKALYF 258
154148849 209 NNFLQ-----HE---------------------IFFG-------PLVPDTAFTSQNLKNFNRIAAIYHDQGLTPLKSLFF 255
34556558  209 NQALG-----RE---------------------LFFG-------PLVPDVAFIPSWRAKFDHYVAMYHDQGLIALKILYF 255
157736900 213 NKYFQ-----KD---------------------IFKG-------PMVPDTVFSPLSRKNFKYFVAMYHDQGLAPLKALYF 259
296272462 219 NKEIG-----KS---------------------IFKG-------PLVPDTAFSPMNRKQYQYYVCMYHDQGLIPLKSLYF 265
224373245 210 NKILD-----KE---------------------FYYG-------PLVPDTAFCSRKGR----FIAMYHDQGLAPLKALYF 252
78777093  211 NKKVC-----FE---------------------QFIG-------PLVPDIAFTPHIREKFKYFIAMYHDQGLAPLKALYF 257
152993274 211 SSIIDplgdaPE---------------------IFTM-------PLVPDVAFTPNVREHYTHYVAMYHDQGLAPLKALHF 262
57238111  314 DKSINVSLNLPIIRVSVDHGTAFDKAYKNAKINTKSYFEAAKFAINLHSKA 364
222823931 312 EKSINVSLNLPIIRTSVDHGTAYDKAYKNEKINLQSYMQAVKSALQFLKIK 362
118475415 259 DKSINVSLNLPIVRTSVDHGTAFDIAYKG-KAETKSYIEAIKFAIKLCDY- 307
154148849 256 EKSINVSLNLPIIRTSVDHGTAFDIAYKG-VAKISSFIEAASWAVKLYETK 305
34556558  256 EESINLSLGLPFVRTSVDHGTAFDIAYRGGNPSLLSYQNAIKMALKLGSDK 306
157736900 260 EESINVSLNLPIIRTSVDHGTAFNIAYKNENVNTQSYINAIKEAINLIQNK 310
296272462 266 EQSINVSLNIPIIRTSVDHGTAFDIAYKNSKVSLKSYINAVKEAINLSK-- 314
224373245 253 DESINVSLNLPILRTSVDHGTAFDIAYKG-KANTKSYENAIKYVLNHKTLM 302
78777093  258 DESINVSLNLPIIRTSVDHGTAFDIAYEK-KAKTLSYINAIKSAIALGERL 307
152993274 263 DEGINVSLNLPILRTSVDHGTAFDIAYKGVKLNNLSYLNAIQYIVDNA--- 310
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