21223940    1 MTDEAEDSGPGGYAAARLRLLTEGA-----RSGPPRRRALAELTDGWLAGLF-------------------GAAT-EEHT 55 
119717491     --------------------------------------------------------------------------------    
57833860    2 GDEYGRTYGCRGLGTQRLRGGPAAPppegaRSGPPRRAALAELTDDWLTGLF-------------------DAGG-AGPR 61 
182435686   6 VTTKTEGSGPSGYAAARLRLLQQEA-----RSGPPRRAALAGLTDDWLTGLFt------------------AAATrAGVR 62 
290957105   6 VRTDAEDSGPSGYAAARLRLLQEEA-----QSGPPRRSALAELTDDWLAGLF-------------------GAGA-AESR 60 
271963324   1 --------------------MRGDT-----RSYAAARKERAADIDRWLTDLLrtacgtpygrtgkngehrtADER-GALS 54 
269127631  10 AATAVEGAGAGGLEEARKA-------------LAAARARRGAELDRWLAGLLe------------------ATGA---AR 55 
117928771   1 MTDHAGVALSAEVVASLDA----------------ARHQRTVARDAWLAALFd------------------AAVA-GNSA 45 
258653313   1 -MRNSPVGMAGGFAELRAQLLSRTG-----VPGPARRKALARLTDGWLGELAq------------------DAGV--NVG 54 
159036835   2 TSLIKKSAAGPDLLINEVVGLPGGI-------DAAARAARAAAIDGWLAGLL------------------------PRRE 50 

21223940   56 GISLVAVGGYGRGELSPRSDLDLLLLHD-GRDDKAVAALADRLWYPVWDLGIDLDHSVRTPQQARKTAGQDLKVHLGLLD 134
119717491   1 ----MAVGGYGRSELAPYSDLDVVLVSDeGV---DVRSVAEQVWYPVWDSGAKLDHAVRTLPEMLTAAEADLKVVLGLLD 73 
57833860   62 GVSLVAVGGYGRGELSPRSDLDLLLLHD-GGDQGAVAALADRIWYPVWDLGLALDHSVRTPAEARKTAGEDLKVQLGLLD 140
182435686  63 GAALVAVGGYGRGELSPRSDLDLLLLHDgSADAAALGALADALWYPVWDLGLALDHSVRTPGEARKTAGEDLKVQLGLLD 142
290957105  61 GVSLVAVGGYGRGELSPRSDLDLLLLHD-GTDERAVAALADRIWYPVWDLGLALDHSVRTPAEARRTAGEDLKVQLGLLD 139
271963324  55 GVALVAVGSLGRAELAPGSDLDLVLLHN-GRDD--VARIADRVWYPVWDSGVGLDHSVRTVEEAATVARDDLKAVLGLIQ 131
269127631  56 EVALVAVGSHSRGELTPGGDLDLVLVHR-GRP--DIAQIADRIWYPVWDRGLRLDHSVRTVREARKVAGSDIKAAMGLLG 132
117928771  46 GLALVAVGGYGRRELGPGSDLDVVLLHT-GRD--DVERIAERIWYPIWDAGQRLDHSVRTISETLAVAASDLRVLLGLLH 122
258653313  55 GVALVAVGGFGRGELSPFSDLDLVLLHStETPASYAGMLAERLWYPIWDSKIRLDHSVRSVGGARQVARTDLPAMLGMLD 134
159036835  51 GVALVAVGGLGRRQCAPYGDLDLLLLHA-GTP--DVDELAAGIWYPVWDAGLRLDHSVRTVAEALAVAQDDLRAALGLLD 127

21223940  135 ARHLAGDLGLTASLRTAVLADWRNQAPKRLPELRDLCAERAERQGELQFLLEPDLKEARGGLRDATALRAVAASWLADAP 214
119717491  74 VRHLAGDPGLTLRLRTTMLAHWRRHARERLPELRELVRARHELAGELAHLSVPDLKEAEGGLRDATVLKALVATWLVDVP 153
57833860  141 ARHLAGDLALTAGLRTAVLADWRNQAPKRLPELQELCAERAERQGELQYLLEPDLKEARGGLRDATALRAVAASWLADAP 220
182435686 143 ARPVAGDLGLVASLRTAVLADWRNQAPKRLPALHELCQERAERTGELQFLLEPDLKEARGGLRDATALRAVAASWVADAP 222
290957105 140 ARHIAGDLGLTAGLRTTVLADWRNQAPKRLPELQELCVERAERQGELQYLLEPDLKEARGGLRDATALRAVAASWLADAP 219
271963324 132 ARHVAGDPELTRAARESVLSEWRADSRRRLGELRDATDKRAEASGELAFLLEPDLRDSRGGIRDVQAMQAVAAAWVASAP 211
269127631 133 ARLLAGDQDLADQLRAVVLTDWRAQARRRLAELAELTRRRWADRGELAFLLEGDLKEAKGGLRDVYTMQAAAATWAVPGP 212
117928771 123 ARTLRGDPALVPTVREQVLRRWRADAPTRLPALAAMCAERAERYGDVAFLIEPDLKEARGGLRDVDALEAIAAAWVAAGP 202
258653313 135 LRHIAGDPDLAVTLHRRVLADWRSDAKNRLADLRASCQERADRSGQLAFATTPDLKESRGGLRDLVVMRAVAASWVADCP 214
159036835 128 ARFVAGDEDLAGRLVRAAAEQWRRTAVRRLPGLREITATRWAAHGELAFLLEGDLKEAAGGLRDVGILRAIALAGVTTAL 207

21223940  215 REGLAEARRRLLDVRDALHLATGRATDRLALQEQDQVAAELGLLDADA------------LLRQVYEAARVISYAGDVTW 282
119717491 154 HGELERTRLALLDVRDVVHETAGRGTDRIAPELWSDVAHRLDLPDARA------------AQVHVRELGRRTAHLSHLTW 221
57833860  221 REGLTDARRRLLDVRDALHLTTGRATDRLALQEQDQVAAELGLLDADT------------LLRQVYEAARVVSYASDVTW 288
182435686 223 REGLDRARRTLLDARDALHLTTGRATDRLALQEQDQVARALGLLDADV------------LLRQVYEAARTVSYATDVTW 290
290957105 220 REGLADARRRLLDVRDALHLTTGRATDRLALQEQDQVAAELGLLDADT------------LLRQVYEAARVISYASDVTW 287
271963324 212 GPRVREAYELLLDIRHSLHLVTARGADRLVLQEQDAVAGTLGLLDAEA------------LMRRLAEAGRTVAHAFDATW 279
269127631 213 GERVRAAHDLLLDVRHALHETTGRAGDRLHLQEQDAVAHLLGLPDGAA------------LLRVIVAAARTVSYAADNLW 280
117928771 203 GPAARAAYRQLLAIRDVLQEVTGRPTTRLVVQEQSAVAERLGLAGSDE------------LLRVVAAAGRTIAYAMDATW 270
258653313 215 HQGLEEARSALLDVRDVVQTVAGRATDRLQVQDQDAVAAQLGLDDRDA------------LLKHVAGIARTVDHASDLTW 282
159036835 208 RPAVRAAHLRLLDTRDALHLRAGRRVDRLVAQERDGVATLLGLRQPAPdpspetvdagdvLLRRVASDARTVRHALDDAF 287

21223940  283 REVGRVLRSRSVRPrlrammngrnggKPVAERSPLAEGVVEQDGEAVLARTARPER-DPALPLRAAAAAAQAGLPLSRHA 361
119717491 222 RRVEAVLARPASYRg-----------ARRPELTRLAPGVALSSGEVVLDNRARPAE-DPVLLLRAAAAAAENDVVLAPAT 289
57833860  289 REVGRVLRSRAVRPrlram---lgggKPVAERSPLAEGVVEQDGEVVLARTARPDR-DPVLPLRAAAAAAQSGLPLSLHA 364
182435686 291 REVNRVLRARSARPrlrallsgglgaRTAPERTPLADGVVDADGEVVLARAARPER-DPVLTLRAAAAAAEAGLPLSRHL 369
290957105 288 REVGRVLRSRAVRPrlram---lgggKPAPERSPLAEGVVEQDGEVVLARAAKPDR-DPVLPLRAAAAAAQAGLPLSLHA 363
271963324 280 RTVDRLLSG-----------------PAPRGRRPLADGVVEHGGEVVLARGADPRK-DPVLVLRAAAAAAEAGLPLAPAT 341
269127631 281 RHVDRFCADRPRGIrva-------rpGGRVERRPVGDGAVEHEGEVVLARGADLT--DPVLPLCVAAAAAQAGLPLAPAT 351
117928771 271 RAVNGSLRR-----------------RPRSPRRPLADGVVEQDGEVVLARGADPRR-DPTLLVRAAAAAAQADLPLAPPT 332
258653313 283 HRVDRALSRPSGTItdlg-----griTRRIERTPLADGIVEQEGEAVLARAVNPAN-DPTLVVRAAAAAAQSGLPVSPAT 356
159036835 288 RAADRLRAGRRGA-------------DGRPVRRPVARDVVVHDGELVLARTVIGARpDPSLSLRVAAAAATTGLPVARAT 354

21223940  362 VRRLAATARPLPTPWPAEAREQLVTLLGSGRPTVQVWEALEAEGLVTRLLPDWERVRCRPQRNAVHLWTVDRHLIETAVR 441
119717491 290 AARLVRECAPMPAPWPDEARQLLVRMLASGRGLRGVWETLEETGALERFLPEWERIRLLPHASAIHRFTVDRHVVETCVA 369
57833860  365 VRRMAAAARPLPTPWPAEAREQLVTLLGSGPSTIEVWEALEAEGLITRLLPDWERVRCRPQRNAVHIWTVDRHLIETAVR 444
182435686 370 VRHLAATARPLPVPWPPEAREELVTLLGAGEATVGVWEALEAEGIITRLLPDWERVHCRPQRNAVHTWTVDRHLVETAVR 449
290957105 364 VRRLAAAAKPLPTPWPAEAREQLVTLLGSGRSTVDVWEALEAEGLITHLLPDWERVRCRPQRNAVHIWTVDRHLIETAVQ 443
271963324 342 VNALAAQSPPLPVPWPDDARDALVALLGAGRAAVPVWEELDQAGVLVRLLPDWERVRHRPQRNPVHRYTVDRHLIEAAAG 421
269127631 352 AEQLAAKVPPLPVPWPAEARDALVSLLGAGPAAIPVWEALDQAGVIVRELPEWEQVRNRPQRNPVHRFTVDRHLVETAAG 431
117928771 333 IATLAAHTPPLPTPWPAQARDAFVALLGAGRPALHVIEGLDQAGVWSRLLPEWQAVRYQRQRHPLHRFTVDRHLVETVIE 412
258653313 357 VLRLARTCPPLPDPWPPVALDAFLSLLGAGEPMLAAWEDLDQAGLISTLLPGWERLRSLPQRDPIHLYTVDRHLMQTAVN 436
159036835 355 CEWLAAYCPPLPTPWPAEARVALITLLGAGPGLVPAWETCDRYGLVDGWLPEWTRVRSLPQHNPVHRFTLDRHLVQTAGE 434

21223940  442 AAGFTRRVHRPDLLLIAALLHDIGKGWPG------------------DHSVAGETIARDVAARIGFDGADTAVLATLVRH 503
119717491 370 ASALIRSVARPDVLMVAALLHDIGKGGLT------------------EHSVAGEPIARDIAERMGFAPDAVDLVTRLVRW 431
57833860  445 ASELARRVGRPDLLLVSALLHDIGKGWPG------------------DHSVAGEIIARDVAARIGFDREDIAVLATLVRH 506
182435686 450 ASLLTRRVQRPDLLLVAALLHDIGKGWPG------------------DHSVAGEVIARDMATRIGFDKHDVGVIATLVRH 511
290957105 444 ASEMTRRVHRPDLLLVAALLHDIGKGWPG------------------DHSVAGEIIAKDVAARIGFDREDVAVLATLVRH 505
271963324 422 AASFTREVSRPDLLLISALLHDIGKGWPG------------------DHSTTGAVVARDIGTRIGLSPADVDILETVVRH 483
269127631 432 AAAMTRDVARPDLLLVGALLHDIGKGRPG------------------DHSRTGAALARTMAARMGFCDTDADVLETVVLH 493
117928771 413 AAALTRRVARPDLLLVGALLHDIGKGFIGgpdgpggaawsgarrsgdDHAERGAAVARTICARMGFSAADTEAVATMVRL 492
258653313 437 AAGLVRRVARPDLLLLAAILHDIGKGPREder------------dhaDHAVVGADLCVPWLRRMGLSEPDVRTVERLIRH 504
159036835 435 AGRHTRDVDRPDLLLLGALLHDVGKGLPG------------------DHSQVGAPIAEAVAARIGLPASEVALIGRLVRL 496

21223940  504 HLLLVETATRRDLDDPATVRAVAQAVGT-----EHTLELLHALTEADALATGPAAWSSWRGSLVADLVKRVSGVLAGE-- 576
119717491 432 HLLLAETATTRDPDDPATAERVASRLGG-----GEALDLLVALTEADARATAPKAWSSWRAGLVHDLARRTRAVLDPH-- 504
57833860  507 HLLLVETATRRDLEDPATVRAVAEVVGS-----QSTLELLHALTESDALATGPAAWSSWRGSLVADLVKRVSAVLAGD-- 579
182435686 512 HLLLVETATRRDLDDPATVRSVAEAVST-----TSTLELLHALTEADALATGPAAWSAWRASLVTDLVKRVGAVLAGE-- 584
290957105 506 HLLLVDTATRRDLEDPATVRSVADAVGS-----PGTLELLHALTESDALATGPAAWSSWRASLVSELVQRVDALFAGDap 580
271963324 484 HLLLPETATRRDLDDPVTISRVAEAVGS-----REVLELLAALAVADGNATGPAAWNSWKASLVTDLVRRVRSVLSGT-- 556
269127631 494 HLLLPDTATRRDLDDPVTIQTVAQKVSAvpgrgRQVLEILAALAVADAQATGPAAWGAWKARLIEELVRRVDACLAGG-- 571
117928771 493 HLLLPQTALRRDLDDPATITSVAEQVGS-----AALLDLLYALAEADSRATG--VWDTWRARLVGELVRRVRASLAGQ-- 563
258653313 505 HLLLGDFAARRDPDDPATIAAIVEAVGD-----AATLDLLAALTESDARAAGPAAWTTWRAGQIRHLVGRVRRALDGE-- 577
159036835 497 HLLLPEVATRRDLADPLTIADVATKVAD-----TSTLELLHALVQADAAATGPAAWSHWKGRLVADLVARVRTTLDTG-- 569

21223940  577 PQPEAE-SAAPTAEQERLAveafrtgGPVLALRAQTEppadsapapsspsspsfpsplsspsspssadgpePLGVELLIA 655
119717491 505 QPPPAV-AVEEVEVPRAVRr------GSTSVVVVPAT-----------------------------------DGSRVTVI 542
57833860  580 APEEPE-AAAPTAEQERLAveafrtgGPVLALRAQTEpgateadn-------------------avpddpePLGVELLIA 639
182435686 585 FPDEPD-DEAPSAEHERLAiealrtgEPVLALHTQPEepagd-------------------------gevePVGVELLIA 638
290957105 581 QEPEPG-ETSAEQERLAIEaf---rtGGPVLSLRAQTeapagdk--------------------dekadpePLGVELLIA 636
271963324 557 PLPPAP-ALSAAQASLARH-------GGGAIRVNGGA---------------------------------------VTVV 589
269127631 572 APPRNGlDPTPEQLALARH-------DGAAVRIAGSR---------------------------------------VTVA 605
117928771 564 APQRPT-VEIPAAVRAAVE-------RGQLAVAADGG--------------------------------------RLIVV 597
258653313 578 RPAEPP-AITQVERELIESgt---gsVGIVIESIPAA-------------------------------------VRITIC 616
159036835 570 AVPEPP-APDPALVT-----------GPLPVVRLTGD--------------------------------------RVAVA 599

21223940  656 VPDQAGVLPAVAGVLAMHRLTVRTAELRSvplp--dgvEGSVLLLDWRVAAQYGSLPQAARLRADLVRALDGTLDIAARL 733
119717491 543 APDRVGLLADVAAALALQRIPVRAARAWS---------QDRYAVSVWEVGV---PDLDAAVLRERLAAVAEGKVDVARRL 610
57833860  640 VPDQSGVLPAVAGVLAMHRLTVRTAELRAlplp--dgvEGSVLLLNWRVAAEYGSLPQAARLRADLVRALDGSLDIAARL 717
182435686 639 LPDRPGVLPAAAGVLALHRLTVRAADLRAvelpnevgeKADLLLLSWRVAAEYGSLPEAARLRADLVRALEGSLDIRARL 718
290957105 637 VPDQAGVLPAVAGVLAMHRLTVRTAELGTfglp--dgvEGSVLLLNWRVAAEYGSLPQAARLRADLVRALDGSLDIAGRL 714
271963324 590 APDRAGLLWRAAGVLAAHRMVVRAASAAS---------AGSTAVIEFAVVPEYGSPPDPATLEADLRLVLAGRLDIEQRL 660
269127631 606 VPDRPGLLWRTAGVLALHRLVVRTARVFAs-------aGAGTAVLDFTAVPEYGTPPDPAALEADLRRMLAGRLDVAGLL 678
117928771 598 APDQPGLLWRSAGVLALHRLGVRAARATS---------IDSTAVTVFDVEPEYLAEIDPDRLREDLRRALDGSLDLSAAL 668
258653313 617 APDRPGLLAAAAAVLTMHRLTVRSAAIRT---------IDGHALQTWIAAPQFGEAPAAATLRADLVRALDGSLDVAARL 687
159036835 600 AADRRGLLTTVAGCLALHRLDVVSADAST---------VFGRALVEFRVQPRYGLAPDPVALGADLRRAVTGDVSVIQRL 670