Conserved Protein Domain Family
PRK02362

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PRK02362: PRK02362 
ATP-dependent DNA helicase
Statistics
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PSSM-Id: 235032
Aligned: 25 rows
Threshold Bit Score: 1116.57
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
292654191   1 MRTADLTg-LPTGIPEALRDEGIEELYPPQAEAVEAGLTDGESLVAAVPTASGKTLIAELAMLSSVARGGKALYIVPLRA 79 
124486563   1 MKINEMP--IPNHLREAYAKNGIEELYPPQAECVNAGLFNRKNILAAIPTASGKTLIAEMAMQKEVAEGGKCLYIVPLKA 78 
88603707    1 MEIASLP--LPDSFIRACHAKGIRSLYPPQAECIEKGLLEGKNLLISIPTASGKTLLAEMAMWSRIAAGGKCLYIVPLRA 78 
73670944    1 MKIESLD--LPDEVKQFYLNSGIMELYPPQAEAVEKGLLEGRNLLAAIPTASGKTLLAELAMLKSILAGGKALYIVPLRA 78 
21226527    1 MKIESLD--LPDEIKRFYENSGILELYPPQAEAVEKGLLEGKNLLAAIPTASGKTLLAELAMLKSVLNGGKALYIVPLRA 78 
20092019    1 MKIESLD--LPDEVKRFYENSGIPELYPPQAEAVEKGLLEGKNLLAAIPTASGKTLLAELAMLKSVLAGGKALYIVPLRA 78 
116754111   2 LTIRDLIrwLPESVIELYEALGIDELYPPQAEAIERGLLDGRNMIISVPTAAGKTLLAELAMLRGALSGKRSLYIVPLRA 81 
126180439   1 MEIADLP--VPPDLAAGYARRGITELYPPQAACVEAGLFSGKNLLVAIPTASGKTLVAEMAMHHQVARGGKCLYIVPLRA 78 
147920885   1 MKIAELN--LPQALKDFYTGSGIPELYPPQAEAIRQGLLDGKNLLAAIPTASGKTLLAEMAMLKSIAEGGKAIYIVPLKA 78 
154151997   1 MQIQDLA--IPEPLRQQYLGLGIRELYPPQAACVERGLLDGKNLLVAIPTASGKTLIAEMAMHRHIANGGKCLYIVPLKA 78 
292654191  80 LASEKKAEFERWEEY-----GIDVGVSTGNYESDGEWLSSRDIIVATSEKVDSLVRNNAAWMDQLTCVVADEVHLVDDRH 154
124486563  79 LASEKYEDFSGK--------SVKVGIATGDPDQRDEYLGRYDIIVATSEKTDSLIRNKAGWLKSISLLVVDEIHLIGDES 150
88603707   79 LASEKYDEFSKKG-------VIRVGIATGDLDRTDAYLGENDIIVATSEKTDSLLRNRTPWLSQITCIVLDEVHLIGSEN 151
73670944   79 LASEKFRRFREFSEL-----GIRVGISTGDYDLRDEGLGVNDIIVATSEKTDSLLRNETVWMQEISVVVADEVHLIDSPD 153
21226527   79 LASEKFRRFQEFSVL-----GMRVGISTGDYDRRDEGLGINDIIVATSEKTDSLLRNETAWMQEISVVVADEVHLIDSPD 153
20092019   79 LASEKFRRFQDFSEL-----GIRVGISTGDYDRRDEGLGINDIIVATSEKTDSLLRNETAWMQEISVVVVDEVHLIDSAD 153
116754111  82 LASEKFESFSRFSKL-----GLRVGISTGDFEKRDERLGRNDIIIATSEKADSLIRNGASWVRRIGVLVVDEIHLLDSAN 156
126180439  79 LASEKFEEFSGK--------GLRVGIATGDFDRRDEYLGRNDIIVATSEKVDSLLRNRTPWLAEISLLVVDEVHLIDDPS 150
147920885  79 LASEKYDRFLEFSKLpikpdGVKVGIATGDFDSRDEYLGEKDIIVATSEKTDSLLRNGASWLSGLSVVVADEVHLIDSPN 158
154151997  79 LASEKYEEFGNK--------GVKVGLSTGDLDRRDDALGKNDIIVATSEKVDSLLRNGARWIPDITLVVIDEIHLIDSPD 150
292654191 155 RGPTLEVTLAKLRRLNTNLQVVALSATVGNAGVVSDWLDAELVKSDWRPIDLKMGVHYGNAVSFADgSQREVPVGRGeRQ 234
124486563 151 RGGTLEMVIAQLRFQNPDMQIIGLSATMGNPESLAKWLDAALITSEWRPVDLREGVYYDGAIHFHG-TERLLETPKK-DD 228
88603707  152 RGATLEMVITKLRYTNPVMQIIGLSATIGNPAQLAEWLDATLITSTWRPVDLRQGVYYNGKIRFSD-SERPIQGKTK-HD 229
73670944  154 RGPTLEVTLAKLRKMNPSCQILALSATVGNADELAVWLEAELVVSEWRPTELLEGVFFNGTFYCKD-REKTVEQSTK-DE 231
21226527  154 RGPTLEITLSKLRRMNPSCQVLALSATVGNADELAAWLDAELVLSEWRPTDLMEGVFYNGIFYCKD-KEKPVGQPTK-DE 231
20092019  154 RGPTLEVTLAKLRKMNPFCQILALSATVGNADELAAWLDAELVLSEWRPTDLMEGVFFDGTFFCKD-KEKLIEQPTK-DE 231
116754111 157 RGPTLEMTMTKLMHLNPEMQVIGLSATIANGREIADWIKGEIVSSDWRPVRLREGVLLEDRLVFPD-GEIQLENRNR-DP 234
126180439 151 RGATVEMVIAKLRHKNPGMQIIALSATIGNPADLAGWLDAELVESEWRPVDLREGVFFEDGIRFAD-SVREVERKSK-YE 228
147920885 159 RGPTLEVTLAKLRKINVNLQILALSATIGNAKALAKWMDAALVQSEWRPTTLKEGVFYGRAITFKK-EKRTVNNAGP-DE 236
154151997 151 RGPTLEMVIAKMRSKNPGMQLIGLSATIGNPKVLAGWLDAELVTSSWRPVDLRQGVFYDNRIQFAE-RMRPVKQVSKnYD 229
292654191 235 TPALVADALEgdgegDQGSSLVFVNSRRNAESAARRMADVTERYVTGDERSDLAELAAEIRDVSDTETSDDLANAVAKGA 314
124486563 229 DLNLLLDTVN-----EGGQCLVFVSSRRSAEAYAKRAAVTLKKT-----SPTLDELSKRIGKADTTASGKNLALAVKSGA 298
88603707  230 DLNLCLDTIE-----EGGQCLVFVSSRRNAEGFAKKAAGALK-----AGSPDSKALAQELRRLRDRDEGNVLADCVERGA 299
73670944  232 AVNLALDTLK-----KDGQCLVFESSRKNCMAFAKKAASTVKKTLSAEDRNALAGIADEILENSETDTSTNLAVCIRSGT 306
21226527  232 AVNLVLDTIK-----EGGQCLVFESSRKNCMGFAKKAVSAVKKTLSNEDRETLAGIADEIIENSETDVSSVLATCVRSGT 306
20092019  232 AINLVLDTLR-----EGGQCLVFESSRKNCMGFAKKATSAVKKTLSAEDKEKLAGIADEILENSETDTASVLASCVRAGT 306
116754111 235 VLNLVLDTVD-----QGGQMLIFESTRRNAESMAKKVSGALQ------ESGETIELAERL--SGEGKTAKKLAMCLRHGA 301
126180439 229 DLDLVLDTVT-----EGGQCLVFVSSRKNAEAFAKRAASGLK-----IANPILAGYADKIRSSASTDMGKILAACVAQGA 298
147920885 237 VNSLVADTLE-----EGGQCLVFANTRKSSESIAQKVARSLSKKLQPAEKEQLAKLKQDVLRHAETDTCEKLAECVGNGV 311
154151997 230 DLNLCLDTIA-----EGGQCLVFVSSRRNAEAFAKRAAGAIK-----SEDAALAACAERLLEGTPTEMVKTLAACVAKGA 299
292654191 315 AFHHAGLAAEHRTLVEDAFRDRLIKCICATPTLAAGVNTPSRRVVVRDWQRYDGDYgGMKPLDVLEVHQMMGRAGRPGLD 394
124486563 299 AFHHAGLPREARAAVEEGFRNGDILCISSTPTLAAGLNLPARRVIIRDYQRYERGA-GMNPIPVLEYRQMAGRAGRPRLD 377
88603707  300 AFHHAGLIRQERTIIEEGFRNGYIEVIAATPTLAAGLNLPARRVIIRDYNRFASGL-GMVPIPVGEYHQMAGRAGRPHLD 378
73670944  307 AFHHAGLTTPLRELVEDGFRAGRIKLISSTPTLAAGLNLPARRVIIRNYRRYSSED-GMQPIPVLEYKQMAGRAGRPRLD 385
21226527  307 AFHHAGLTTPLRELVENGFREGRIKIISSTPTLAAGLNLPARRVIIRSYRRYSSDS-GMQPIPVLEYKQMAGRAGRPRLD 385
20092019  307 AFHHAGLTSPLRELVETGFREGYVKLISSTPTLAAGLNLPARRVIIRSYRRYSSDS-GMQPIPVLEYKQMAGRAGRPRLD 385
116754111 302 AFHHAGLLPEQRRLIELGFRQNVVKVIACTPTLAAGLNLPARRVLIRSYKRYEAGL-GTRPIPVMEYRQMAGRAGRPGLD 380
126180439 299 AFHHAGLSREERQLVEAGFREGQIKVISSTPTLAAGLNLPARRVIVRDYLRFNAGE-GMMPIPVREYRQMAGRAGRPRLD 377
147920885 312 AFHHAGLKGEHRRIVEDGFRQNILKVIACTPTLAAGLNLPARRVIIRDYKRFDVNY-GSVPIPVLEYKQMAGRAGRPRLD 390
154151997 300 AFHHAGLSRKERSIVEEAFRKNLLKCISSTPTLAAGLNLPARRVIIRDYLRFSAGE-GMQPIPVSEYRQMAGRAGRPRLD 378
292654191 395 PYGEAVLLAKDADARDELFERYIWADAEDVRSKLAAEPALRTHLLATVASGFAHTREGLLEFLDQTLYATQTDDPeRLGQ 474
124486563 378 PYGEAVLIAKQQRDVDRLFEEFIDAPAEDITSQCQRENELRSHLLALITSGFAQTDGEVRGFMEKSFYASQKSVHrRLDK 457
88603707  379 PYGEAVLLAKDAPSVERLFETFIDAEAERVDSQCVDDASLCAHILSLIATGFAHDQEALSSFMERTFYFFQHPKTrSLPR 458
73670944  386 PYGEAVLVAKSYKEFVFLFENYIEANAEDIWSKLGTENALRTHVLSTISNGFARTYDELMDFLEATFFAFQYSNF-GLST 464
21226527  386 PYGEAVLLAKSYEEFVFLFEKYIEAGAEDIWSKLGTENALRTHILSTISNGFARTREELMDFLEATFFAFQYSNF-GLSA 464
20092019  386 PYGEAVLLAKSYEELLFLFEKYIEAGAEDIWSKLGTENALRTHVLSTISNGFARTKEELMDFLEATFFAYQYSNF-GLSV 464
116754111 381 PYGESLIMARSESELQKLMDHYVMGEPEDIWSKLASERALRTHVLATIASRFADSVDSLSRLMASTFYARQQDPS-YLGE 459
126180439 378 PYGEAVLIAKSEEMVDELFDYYIEAMAEDVRSRCAEEAVLCTHILSLIATGFARERGEVLGFMDGTFYAHQGESPrALKR 457
147920885 391 PYGEAVLIAKNYDEFGELMENYINADPEHITSKLGTEPAMRAHALSAVATDFCRSRQDLKAFMDTTFFAYQRg---DLSH 467
154151997 379 PYGEAVLIAKEAEQVPELFEVYIEAEAEDVHSRIAEPTALYTHVLSLVASGFAGTRGELTEFMNRSFYVHEHKQGrLIHR 458
292654191 475 VTDRVLDYLEVNGFVEFE-GETIQATPVGHTVSRLYLDPMSAAEIIDGLewaadhrteklralagetpekptrdrsesde 553
124486563 458 NIEKTLAYLEKSGMVERE-GDEIHGTLFGALTSRLYLDPESAMMIKDGL------------------------------- 505
88603707  459 LVADAIRFLTTAGMVEER-ENTLSATRLGSLVSRLYLNPCTARLILDSL------------------------------- 506
73670944  465 VVNECLNFLRQEGMLEKD--DALIPTSFGKLVSRLYIDPLSAARIAKGL------------------------------- 511
21226527  465 VVDECLDFLRREGMLEKD-PDALVSTVFGKLVSRLYIDPLSAALIAKGL------------------------------- 512
20092019  465 VVDECLNFLRQEGMLEQD-SDALISTMFGKLVSRLYIDPLSAALIAKGL------------------------------- 512
116754111 460 TIASVLEFLVRSDMIDKD----LTPTPLGALVSRLYIDPLSAMVMIQEI------------------------------- 504
126180439 458 AVDRVLEFLREAEMITEV-GEWLEATEYGSLVSRLYIDPRSAEVIVNAM------------------------------- 505
147920885 468 VIDNVLNFLLEENMIIESkGGSLKATDLGSLVSKLYIDPLSAALIAEGL------------------------------- 516
154151997 459 AIDEALQFLITAEMVVEV-GEHIGATELGTLVSRMYIDPRSAFAIVTTL------------------------------- 506
292654191 554 sggfqrasemvaddgdggggeDGVGAngdgdsddadgvetdrtyPTPLGLYHLVCRTPDMYQLYLKSGDRETYTELCYER 633
124486563 506 ---------------------AGKK-------------------FTAFGMLHLLCMTPDMFRFYLKASDEKFVDKILKER 545
88603707  507 ---------------------KSCKT------------------PTLIGLLHVICVSPDMQRLYLKAADTQLLRTFLFKH 547
73670944  512 ---------------------KGAKS------------------LSELTLLHLVCSTPDMRLLYMRSHDYQDINDYVMAH 552
21226527  513 ---------------------REAGT------------------LTELTLLHLICSTPDMRLMYMRSQDYQEVNDYVMAH 553
20092019  513 ---------------------REAGT------------------LTELTLLHLVCSTPDMRLMYMRSQDYQDINDFVMAH 553
116754111 505 ---------------------RGIRR------------------PTVLTLLHVITMTPDMELLFVQQSD-NWLEDFISEH 544
126180439 506 ---------------------TRQKE------------------YTDIGFLHLLCATPDMPTLFVRKNDMYALDRFLADH 546
147920885 517 ---------------------EKAKKrp---------------dVAEFGLLHLICSTPDVKSLYLRRGDYSWIIRYADEH 560
154151997 507 ---------------------REQEK------------------YADLGLIQLICTTPDMPTLYAKNADLPALSRMLEVR 547
292654191 634 EPEFlGRVPSEY-EDVAFEDWLSALKTAKLLEDWVGEVDEDRITERYGVGPGDIRGKVETSEWLLGAAERLATELDLDSV 712
124486563 546 SEELl--------LDDLSEEFFAAIKTALVAEEWISEIGEDSICERFGVGAGDIHAVVENLRWLMHAAGRICHEFAADCD 617
88603707  548 KDDLiLPLPF---EQEEEELWLSGLKTALVLTDWADEFSEGMIEERYGIGAGDLYNIVDSGKWLLHGTERLVSVEMPEMS 624
73670944  553 ASEF-VKVPSPF-DTTEYEWFLGEVKTSLLLLDWIHEKSENEICLKFGTGEGDIHSIADIAEWIMHVTSQLAGLLDLKGA 630
21226527  554 AGEF-SKVPNPF-NIAEYEWFLGEVKTSLLLMDWIHEKPENEICLKFGIGEGDIHATADIAEWIMHVTAQLAGLLDLKGA 631
20092019  554 AEEF-SKVPSPF-NIVEYEWFLSEVKTSLLLMDWIHEKPENEICLKFGTGEGDIHTTADIAEWIMHVATQLARLLDLKGA 631
116754111 545 SSEL-------G-NEKNFDWLLREVKTASMLMDWINEVHEDRIEDRYSISPGDLVRIAETAEWLMSALHRISKHMDLGVT 616
126180439 547 RDELwMEIP--W-DAD--EGFDRSLKTALLLADWGDEVGEDVICERYSVGPGDVYGMVESVAWLVHASRHLAGLFAPHLK 621
147920885 561 ASDFlSDVPDSYgDDVEFEQFLAGVKTAALAEMWINEKSEEAITTFFNIGPGDIRNLMETCTWLMHGTAEISALLGAPAT 640
154151997 548 GADIwLPPP--L-DDDAAETYYRAVKTAMLLSDWTDELSEEKICERYGVGPGDVFGMVENINWLLHATSQLARMFVPKFY 624
292654191 713 YAVREAKKRVEYGVREELLDLAGVRGVGRKRARRLFEAGVETRADLREADKPRVLAAlrGRRKTAENILEAAGRKDPSMd 792
124486563 618 DEMRDLELRVTHGVKEELLPLIALKGIGRVRARRIFDRGITSPEKLMAAEKDEVVSI--LGATIAKNVLEQAGRRSAKKr 695
88603707  625 QVVKTLSVRVHHGVKSELLPLVALRNIGRVRARTLYNAGYPDPEAVARAGLSTIARI--IGEGIARQVIDEITGVKRSGi 702
73670944  631 REAAELEKRIHYGAAPELIDLLNIRGIGRVRARKLYEAGFKSSAELAEVDPEKVAAL--LGPKIADRIFKQIRGRGTSSg 708
21226527  632 KEASELEKRIRYGAAPELMDLLDIRSVGRVRARKLYEAGFKSTAELAAASPEHIAVL--VGPKITERIFKQIGRREAVSe 709
20092019  632 KEAAELEKRIHYGAGPELMDLLDIRGIGRVRARKLYGAGFKSTADLAGATPEKVAAL--VGPKIAERIFRQIGRREAVSe 709
116754111 617 YLAERLALRIHYGAGDELLQLLELKGIGRVRARKLYQAGYRSLEDLKAADKSTLSEI--LGPKIAEGVISQLKEPGVSA- 693
126180439 622 APIEEMELRTKHGIKKELLPLIRIRGIGRVRARRLFNNGIDSIEALREAGPEKVGKV--LGQGIAAQVFEQLDGVRDEI- 698
147920885 641 RTARELAIRIENGASRELLDLITLKGVGRVRARKLYDAGYTSRDKLKAAEIPAIAAIpgIGDKLAVSIMSQLGRKVDHT- 719
154151997 625 GQIADCEICMKNGIRRELLPLVRLRGIGRVRARRLFNNGITSPEELSRHKKEDLVKI--LGSGIAEQVLEQLHPSKDTGk 702
292654191 793 avdedda-------------------------------------------------------------pddavpdDAGFE 811
124486563 696 eqel------------------------------------------------------------------eesedEHEEE 709
88603707  703 hssdddyqqktpelltdipgigkkmaeklqnagiitvsdlltadevllsdvlgaararkvlaflsnsekensssdKTEEI 782
73670944  709 --------------------------------------------------------------------------iIASEP 714
21226527  710 --------------------------------------------------------------------------fSDIEP 715
20092019  710 --------------------------------------------------------------------------iSDSER 715
116754111     --------------------------------------------------------------------------------    
126180439     --------------------------------------------------------------------------------    
147920885 720 ----------------------------------------------------------------------------PPET 723
154151997 703 ---------------------------------------------------------------------------KEPPS 707
292654191 812 TAKERADQQASLGDFE 827
124486563 710 DLPTEKKPQATLFDFG 725
88603707  783 PDTQKIRGQSSWEDFG 798
73670944  715 PEKSPYSGQKTISDY- 729
21226527  716 LEKGSSDGQRTISDY- 730
20092019  716 LEKSSQDGQSTISDF- 730
116754111     ----------------    
126180439 699 --GGVGEEQSTLSRFG 712
147920885 724 EEQPQVSGQSTLFSFD 739
154151997 708 GDKNTNPGQSTLFHFG 723
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