Conserved Protein Domain Family
truD

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PRK00984: truD 
tRNA pseudouridine synthase D; Reviewed
Statistics
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PSSM-Id: 234884
Aligned: 230 rows
Threshold Bit Score: 239.341
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
110667248   4 SPSReqtvGIEYYYSDTDG-----TDGRLRVRPADFQVREIETIEPepiDASVgdyPHVLLRVTLSKWDTNDFVQQLSDN 78 
297619948   1 --------------------------MKLRQKPEDFKVQELLNLENilvKEDSsekNYKIYELCKKNMENLKAISYISKS 54 
150401583   1 --------------------------MKLRQTNGDFIVNEILDNEFikeNPSG---NYSLYILKKSNIENLKALNYISKN 51 
159905320   1 --------------------------MKFRQKHEDFIVNEILDYEL---DDSG---NYSLYKLQKNGIENLKAISYLSKN 48 
15606802    1 ------------------------MDIRIKEKPEEFYVKEIKKLDL---KEKG---QYAYFLLKKKDMTTLDAVRHISHR 50 
161579521   1 MKNIstkeSFFKFKFNNRSlycwgAFMKLRMKPEDFIVEEIIDFNK---IAGD---RCYLYKLTKRNIESLKAFSYIAKK 74 
256811289   1 --------------------------MKLRMKPEDFIVEEIVDFDK---ISGN---KCYLYKLTKRNIESLRAFSYISKK 48 
261403290   1 ------------------------------MKPEDFIVEEIINPEK---IAGD---KCYLYILTKKNIESLKALSYISKK 44 
289192050   1 --------------------------MKLRMKPEDFIVEEIIDFDK---ISGN---KCYLYKLTKRNIESLKAFSYISKK 48 
296108899   1 ------------------------MKVKLRVKPEDFIVEEVLDLNK---VKGS---KCYLYKLTKRNIECLKALSYISKK 50 
110667248  79 LEISRERVSWAGTKDKYAITTQLFSI-----ARINPNNKSlT--AIPNADIEVLGRIGRPLQFGDLGGNSFEICVRSAT- 150
297619948  55 QEIPLKEIGYCGLKDRHAITKQYISI--------PEEYEInI--KENNLKLTFIGYSSEKLTIGDLIGNEFEITIRNIDk 124
150401583  52 CNIPINDIGYCGLKDKYAITTQYISI--------PTKYDK-IelNEKNLTLKYLKTINSPLKIGSLMGNSFKITVRAIDk 122
159905320  49 FEVPTKEIGYCGLKDRHAITTQYVSI--------PNEYGK-LslNEDNLKLEYIGNIEKPLKIGKLYGNRFEIIARAIDk 119
15606802   51 FGIPLKNIGFAGLKDKKAVTEQYISVkd-lnEEKIRKMDG-Y--RTENLELKFLGFSDKGLELGEIEGNYFEVVVRGVTk 126
161579521  75 FKIPLKDIGYCGLKDRHALTTQYISI--------PKKYGK-LslDEPNLK-LELIGESKFLLLGDLEGNRFTITVRGLKk 144
256811289  49 FRIPLRDIGYCGLKDRHALTTQYVSI--------PKKYGK-FslDEPNLK-LELIGESKFLLLGDLEGNRFTITVRGLKk 118
261403290  45 FKIPLKDIGYCGLKDRHAITKQYISI---------PKYYKkLylEEPNLK-LKPIGISRFLLLGDLEGNKFTITIRGIKk 114
289192050  49 FKIPLRDIGYCGLKDRHALTTQYISIpkkygKLS-------L--DEPNLK-LELVGESKFLLLGDLEGNRFTITVRGIKk 118
296108899  51 FKIPLKDIGYCGLKDRHALTIQYISI--------PKKYGK-LslNEKNLK-LELVGESRFLKLGDLEGNKFKIVVRDL-- 118
110667248 151 -DTSVVDAITAELHaytvsnnhsqdddtqsvyagdtnkvSIAFPNYFGHQRFGSRrpithrvgraivrnawrdavlqyva 229
297619948 125 tYFLDIAENIRNL--------------------------EQGVPNYFDNQRFGSVfegkfiaeymlknnfeeifki---- 174
150401583 123 nDFSNISKNLQNLE--------------------------QGAPNYFDDQRFGSVfhnqfiakyylkgeyekalki---- 172
159905320 120 nEFLKIADNMRALS--------------------------FGAPNYYDDQRFGSVfngkfiakeilkgnyeevvki---- 169
15606802  127 -YHRRVFPRMKELVe------------------------NYGCENYFGEQRFGSVkhaeefivkyllrheyee------- 174
161579521 145 eDIPKIKENLKYL--------------------------EFGAPNYFDSQRFGSVfdkkfiakevikgnyeeavki---- 194
256811289 119 eDIPKMKENLKYL--------------------------EFGAPNYFDSQRFGSVfdkkfiskevikgnyeeavki---- 168
261403290 115 eDIPKLEENLKYL--------------------------DMGAPNYFDSQRFGSVfdgkfiakeiimgnieeavki---- 164
289192050 119 dDIPKIKENLKYLE--------------------------FGAPNYFDSQRFGSVfdkkfiakevikgnyeeavki---- 168
296108899 119 -GEEHLKRFYENVNy------------------------IEKIPNYFDSQRFGSVfnkkfivkeiikgnyeealki---- 169
110667248 230 nsfesepettqrarefaseqagssRPDWEEaiermpnalrfeqsmlhrlneananidsdAATWRH-------------Al 296
297619948 175 ----lltkygksenktikdlkryiAKNWGDwekcyqylsennik--skmyinvlkklknTGKYKE-------------Ay 235
150401583 173 ----ilteytrsenkrikdlkrniKKNWNKwdniieyikn---------nkinskmfvnIIKYLNnpernnnykeafkY- 238
159905320 170 ----lltsytksenkqlkdlkrfiAKNWGNwdeclnyidkkq------ikskmfrnmvkSLKYENdf---------kkSf 230
15606802  175 ------amkeyltslgdkrlkrllRKAWRDwdrflslmpk---------gakpelevvkALRRGEsf---------knAf 230
161579521 195 ----lltkykksekklikdlkrfiDKNWGDwdkiwey---------------ikennikSRLYVNmvkelkksndykkAl 255
256811289 169 ----lltkykksekkiikdlkrfiAKNWGDwnkiwny---------------ieknnikARLYVNmvkelkesgdykkAl 229
261403290 165 ----lltrykksekkrikdlkrfiSKNWGDwekiwky---------------ikennikAKMYVNivkelkksgdykkAf 225
289192050 169 ----lltkykksekkiikdlkrfiSKNWGDwdkvwnyikennik--aklyvnmvkelkkSNDYKKalsy-----vddrL- 236
296108899 170 ----iltqykksenkriknfkrfvNQHWGDwekiwdy---------------iknkdirAKLYVNiikelkesndfkkAl 230
110667248 297 maVPKNLQRLFVNAAQSDLFNRIISERLRHDIPIH-----RPIAGDIVCFQDQnsptevirpdpaRTQLTTERrv---dI 368
297619948 236 kyIDVRLNDLFIAAYQSYLWNESVKEYLKSVLPVEnriyiDYDCGSLLYYSKI------------DKKLFEELkikempL 303
150401583 239 --VDNRLKKLFVLSYQSYLWNECIKELLKTKLPKEqrkyvDYSCGTFLYYSKId------------------------nE 292
159905320 231 kyVDNRLKELFISAYQSYLWNECLKEFLK-----------EFIPKDSRKYVDYs----------cGTFLFYETld---eE 286
15606802  231 mvLPKNIRLMFVFAYQSYLWNRYLYTFVVRYLKYC------------------------------KTPFLKWElaf-fnD 279
161579521 256 syVDDRLKKIFVAAYQSYLWNECVKELLRKYVPEEdrvyyEYECGTLMFYKKMd------------------------eE 311
256811289 230 syVDDRLKKIFVAAYQSYLWNECVKELLSKYIPEEdrvyyEYECGTLMFYKKMd------------------------eD 285
261403290 226 nyVDDRLKKLFLSAYQSYLWNECIKELLKEYIPKEdrvyyEYECGSLLFYKKLd------------------------eN 281
289192050 237 -------KKIFVAAYQSYLWNECVKELLKKYIPEEdrvyyEYECGTLMFYKKMd------------------------rE 285
296108899 231 tyIDDRLKKLFLAAYQSYLWNECVKEILKNKVNEPly--yNYECGTLLFFKEL------------KEELEFKDfp--tiA 294
110667248 369 MQRHCERGRAFVTAPLVGTQTNFA--SGKPGEIEKSVLAEydit-------pedfDLPGTFDSRGTRRAMALQT------ 433
297619948 304 LYDKLDKNLLEIDEELVNAINIVL--KRNKLKFKDFSDDN-----------------LIKGKFRNFNRPILNIP------ 358
150401583 293 LFNTLKKDKFPTIAPDIDYNNHKDeyYNIILKILRKERASlkd----------fnNLMELNKLSYVERDILNIP------ 356
159905320 287 LFDKLKEMDFPTIVSDVEYTDSEK--KIINAILKKERIKFsd------------fEKLDFGKLKYTKRPIISIP------ 346
15606802  280 MSEVIWEEIKDLEIPYLGVEYKPR--NKKAEIVMKEVLQD---------------EGITPKMLMAERIGIKLFS------ 336
161579521 312 VFNILKDKKFPTIAP-----------DIEYSGEEKEIIEEilkregl--tmeelnNIGELGKFIYSERKILSIP------ 372
256811289 286 IFNMLKDKKFPTIAP-----------DIEYSGEEKKIIEKilknegv--gikdlnNIGDLGRFIYSERKILSIP------ 346
261403290 282 SLNYLKNLKFPMISP-----------EAHYSEKEQKIIERvlkkenikiedlqkeDLKILGNFVRGERDVISIPknlkig 350
289192050 286 VFNLLKDKKFPTIAP-----------DIEYSGEEKEIIEEilkregi--tmedlnNIGGLGRFIYNERKILSVP------ 346
296108899 295 LDSNYNEEERKIIDRVL---------KREGIRLEdl------------------dRAKIFGKFVYTRRDILMEP------ 341
110667248 434 ----NIStkadcnt---dsdkhniDqsgqSYKLVFTLPPGAYATAVLREYLKVAP 481
297619948 359 ----ENLeygkfksd-------elnngkyKITIKFSLKKGSYATGIIKGVFNSVK 402
150401583 357 ----KNIkygdfepd-------efnkgkyKITIEFELNKGSYATIIIKRIFNIQ- 399
159905320 347 ----EEVntgtfks---delnskkY----KITLEFSLKKGSYATIILKRVFNIL- 389
15606802  337 ----DGVrkaffkpqglkvieerkN----SLKLSFTLPPGSYATILLRKLFCSDV 383
161579521 373 ----KNLkigef-------eedelNkgkyKITLSYELEKGSYATIIIKRAFLGVK 416
256811289 347 ----KNLkigdf-------eedelNkgkyKITLSYELEKGSYATIIIKRAFLGVK 390
261403290 351 diveDDLvkg-----------------kyKITLTFELKKGSYATIIIKRAFLGIK 388
289192050 347 ----KNLkigefee---delnkgkY----KITLSYELEKGSYATIIIKRAFLGVK 390
296108899 342 ----KDFrysvked----eiyrgkR----KVELEYFLKKGSYATMVIKRLFL--- 381
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