Conserved Protein Domain Family
PLN03191

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PLN03191: PLN03191 
Type I inositol-1,4,5-trisphosphate 5-phosphatase 2; Provisional
Statistics
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PSSM-Id: 215624
Aligned: 7 rows
Threshold Bit Score: 1113.44
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
18415007    1 MKTRRGKRPERFWPSIVMNKWLNRKPKVYDFSEDEIDTEPESEDDVCSVKDvpnVHCVTDEDSHNGRRGSEADHGNNISD 80 
30684260    1 MKTRRGKRPERFWPSIVMNKWLNRKPKVYDFSEDEIDTEPESEDDVCSVKDvpnVHCVTDEDSHNGRRGSEADHGNNISD 80 
255573423   1 MRTRRGKRSEAFWPSIVMKKWLNIKPKVYDFSEDEY-TETESEDDACSLKD---ERVNVDEDHAPRIQVNQSSFQGQISD 76 
225427320   1 MRTRQGKRSEAFWPSIVMKKWLNIKPKAYDFSEDEVDTETESEDDACSLKD---ARVQMGEDHACRMQRNQSVCTNQTSG 77 
224126543   1 MRTRRGKRAEAFWPSLVVKKWLNIKHKVNDFSEDEY-TETESEDDAPSVKD---DRVNVDEDRAHRIQGNQSVFRSQISG 76 
224138048   1 MRTRRGKRAEPFWPSLVMKKWLNIKPKVYDFSEDEY-TETESEDDASPVKD---ERVNVNEDHANRTQGNPYVFQSRISG 76 
297800268   1 MKTRRGKRPERFWPSIVMNKWLNIKPKVYDFSEDEIDTEPESEDDVCSVKDvpnVHCVTDEDSHNGRRGSEADHGNIISD 80 
18415007   81 GG---VSVRGGYQRKHRRGKSETLRAQYINTKDIKVTVATWNVAGKRPSDDLEIEDWLSTDNPSDIYIIGFQEVVPLNAG 157
30684260   81 GG---VSVRGGYQRKHRRGKSETLRAQYINTKDIKVTVATWNVAGKRPSDDLEIEDWLSTDNPSDIYIIGFQEVVPLNAG 157
255573423  77 AP------TKGYSVRHRRGKSETLRAQYINTKDVRVTIGTWNVAGRLPDEDLEIDDWLSTEEPADMYIIGFQEVVPLSAG 150
225427320  78 KE------SKGYSSSHRRGKSETLRVHYINRKDIRLTIGTWNVAGRLPNEDLEIEEWLCMQEPADIYILGFQEVVPLNAG 151
224126543  77 NNl-fYAPSKGYSSGHRRGKSETLRAQYINTKDVRVTIGTWNVAGRLPNEDLDIDSWLCPEEPADIYIIGFQEVVPLNAG 155
224138048  77 NNpflYAPSKGYPSRHKRGKSETLRLQYINMKDVRVTIGTWNVAGRLPYEDLDIDDWLCTEEPADIYIIGFQEVVPLNAG 156
297800268  81 GG---VSVRGGYQRKHRRGKSETLRAQYINTKDIKVTVATWNVAGKRPSDDLEIEDWLSTDNPSDIYIIGFQEVVPLNAG 157
18415007  158 NVFGAEDRGPIPKWESIIRRTLNKSNKEsvydqspscnnNALHRSHSAPSSPILaqeANSIISHVMVENlVADHSLDLAT 237
30684260  158 NVFGAEDRGPIPKWESIIRRTLNKSNKEsvydqspscnnNALHRSHSAPSSPILaqeANSIISHVMVENlVADHSLDLAT 237
255573423 151 NVLGAESSRPIPKWEAIIRRTLNKFSHP-----------ESKHKCYSAPPSPVL---RTSSVADELAGE-VDALPLEMMN 215
225427320 152 NVLGAEDSQPIPKWEAIIRRTLNKSFEP-----------ESEYKSYSAPTSPVL---RASCVADALKEE-VDSPTLEMMN 216
224126543 156 NVLGAESSRPIPKWEAIIRRTLNKSHQA-----------ESKHKCFSAPPSPVL---RTSSVADELADE-VDSLPLEVMN 220
224138048 157 NVLGAESNRPITKWEEIIRRTLNKSLQP-----------ERKYKCYSAPPSPVS---RTSLVADELADE-VDSLPLEMIN 221
297800268 158 NVFGAEDRGPIPKWESIIRRTLNKSNKEsvddqspscnnNLLHRSHSAPSSPNLaqeANSIISDVMVENlVADHSLDLAT 237
18415007  238 NEFIDAATALPSLEPQRNPNMD--------------------WPELALDSNPQ-IVGSEGKLRRVFSSNATLGFKLPENP 296
30684260  238 NEFIDAATALPSLEPQRNPNMD--------------------WPELALDSNPQ-IVGSEGKLRRVFSSNATLGFKLPENP 296
255573423 216 EEFAGTAVGYDYETDELNKIIGarknlqlkriygidcdsrldWPEHSLEATPQ-VISSNSKLRRVMSSSAGMGFNWTQDP 294
225427320 217 NETAAPTNGCNLERHKLNGMIGtgkkfqlrrlyggdsdirldWPEYSLDKVPQ--VLSNLKLRRVLSSSARVGFGWMETP 294
224126543 221 EEYIEAADGCESDILEFGKAIGigknlhlkrvygidcdskldWPEHSLAATPQ-VISSNSKLRRVSSSSARIGFNWSENP 299
224138048 222 EEYIEATDGCESNILEFGKAIA--------------------WPEHSLAATPQeVISSNSKLRRVSSSSARIGFSWTENP 281
297800268 238 NEFIDAATALPSLEPERNPNMD--------------------WPELALDSNPQ-IVGSEGKLRRVFSSNATLGFKLPENP 296
18415007  297 S--GASRFASEARQLKRS-RSFETLNLSWNDIKeeidnrssssseaeeaakimhddssdgdsssqdEEDGDKIRNSYGLP 373
30684260  297 S--GASRFASEARQLKRS-RSFETLNLSWNDIK---------------------------------EEDGDKIRNSYGLP 340
255573423 295 FrlSPHNFAINGKGLRRShHSFGNLGSICVEERersevpeglevld--------slsdvsdrsseaEDDTFPEVPGDQNN 366
225427320 295 InfSPQKVTLDGGGMKRSyRSSGNLGLIFMEQQersklcdyls--------------dvsdrsseeEDESLIEIPEHQFK 360
224126543 300 SlfSPQHIALNRSGLKRShQSSGNLGSMWLEREqrhevpevpevpev-----idsfsevsdwlseaEDDTFLEVPSEQYY 374
224138048 282 SlfSPQNIALNRSGLKRShHSFGNLGSMWLEQQqrhkvpevpevid--------sfsevsdwlseaEDDTFLEVPSDQCY 353
297800268 297 S--GASRFASEARHLKRS-RSFETLNLSWNDIKedidnsssssseaeeaakimhddssdgdsssedVEDGDKIGNSYGLP 373
18415007  374 EDLVEECRKVKdsQKYVRIVSKQMVGIYVSVWIRRRLRRHVNNLKVSPVGVGLMGYMGNKGSVSISMTLYQSRMCFVCSH 453
30684260  341 EDLVEECRKVKdsQKYVRIVSKQMVGIYVSVWIRRRLRRHVNNLKVSPVGVGLMGYMGNKGSVSISMTLYQSRMCFVCSH 420
255573423 367 DGHIMGKGKSH--TKYVRIVSKQMVGIYVSIWVRKTLRRHINNLKVSLVGVGLMGYMGNKGSVSISMSLFQSRLCFVCSH 444
225427320 361 DGENKDCMKSR--QSYVRIVSKQMVGIYISVWVRKRLRRHINNLKVSPVGVGLMGYMGNKGSVSVSMSVFQTRICFVCSH 438
224126543 375 SEIIKDNDDPR--PKYVRIVSKQMVGIYVSIWVRKRLRRHINNLEVSPVGVGLMGYMGNKGSVSVSMSVFQSRLCLVCSH 452
224138048 354 SEIIKDNGKPL--TKYVRIVSKQMVGIYVSIWVRKRLRRHINNLEVSPVGVGLMGYMGNKGSVSVSMSLFQSRLCFVCSH 431
297800268 374 EDLVEECRKVKdsQKYVRIVSKQMVGIYVSVWIRRRLRRHVNNLKVSPVGVGLMGYMGNKGSVSISMTLYQSRMCFVCSH 453
18415007  454 LTSGHKDGAEQRRNADVYEIIRRTRFASVLDTDQPRTIPCHDQVFWFGDLNYRLNMSDGEVRKLVSQKRWDELKNSDQLI 533
30684260  421 LTSGHKDGAEQRRNADVYEIIRRTRFASVLDTDQPRTIPCHDQVFWFGDLNYRLNMSDGEVRKLVSQKRWDELKNSDQLI 500
255573423 445 LTSGQKDGAEQRRNADVYEIIRRTQFSSVFDTDQPQTIPSHDQIFWFGDLNYRLNMLDSDIRKLVSLKQWDELINTDQLI 524
225427320 439 LTSGHKDGDKQRRNSDVYEILRRTQFSSVIDADQPETIPSHDQIFWFGDLNYRLNMLDAEIRKLVARKKWDELINSDQLS 518
224126543 453 LASGQKDGAEQRRNADVCEIIRRTRFSSILDTNQAQTIPSHDQIFWFGDLNYRLNMLDTEVRKLVAMKQWDELINNDQLS 532
224138048 432 LTSGQKDGAEQRRNADVYEIIRRTHFSSVTDANQPQTIPSHDHIFWFGDLNYRLNMLDTEVRKLVALKKWDQLINSDQLS 511
297800268 454 LTSGHKDGAEQRRNADVYEIIRRTRFASVLDTDQPRTIPCHDQVFWFGDLNYRLNMADSEVRKLVAQKRWDELKNSDQLI 533
18415007  534 RELRRGHVFDGWREGPIKFPPTYKYEFDSDRYAGENLREPEKKRAPAWCDRILWLGKGIRQECYKRSEIRMSDHRPVTSI 613
30684260  501 RELRRGHVFDGWREGPIKFPPTYKYEFDSDRYAGENLREPEKKRAPAWCDRILWLGKGIRQECYKRSEIRMSDHRPVTSI 580
255573423 525 KELRSGHVFDGWKEGMINFPPTYKYEINSDRYIGENPKEGEKKRSPAWCDRILWYGKGIKQLFYKRTDMRLSDHRPVSSM 604
225427320 519 KELRSGHVFEGWKEGVIDFPPTYKYEINSDRYVGENPKEGEKKRSPAWCDRILWLGKGIKQLCYNRAEIRVSDHRPVSSN 598
224126543 533 KELCGGRVFEGWKEGAINFPPTYKYEINSDTYVGENPKEGEKKRSPAWCDRILWLGKGIKQLSYKRSELRLSDHRPVSSM 612
224138048 512 KELRSGHVFEGWKEGVISFPPTYKYEINSDRYVGENPKEGEKKRSPAWCDRILWFGKGIKQLSYKQSELRLSDHRPVSSM 591
297800268 534 RELRRGHVFDGWREGPIKFPPTYKYEFDSDRYAGENLREGEKKRAPAWCDRILWLGKGIRQECYKRSEIKMSDHRPVTSI 613
18415007  614 FNVGVEVFDHRKLQRALHVNNAA-------------------------------ASAVHPEPSF 646
30684260  581 FNVGVEVFDHRKLQRALHVNNAA-------------------------------ASAVHPEPSF 613
255573423 605 FLVEVEVLDHRKLKKAINVSSAAgikdninkvykkllldhcegeneianaalkfCKRVHHNQAF 668
225427320 599 FMVEVEVFDHRKLQRALKPTDAR----------------------------------VHPEIFL 628
224126543 613 FLVEVEVLDHRKLKKALNVNSAA----------------------------------VHPEIFL 642
224138048 592 FLVEVEVFDHRKLQKALNVNSAA----------------------------------VHPE--- 618
297800268 614 FNVGVEVFDHRKLQRALHVNNAA-------------------------------ASAVHPEPSF 646
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