225435112   1 MDEELLELQRQLEFAQQVKSSIRLSERN-----VVELVQKLHELRIIDFDLLHTVSGKEYITPEQLRHEMAAEIKKLGRV 75 
168057465   1 MDLELEELQKLFEQTQNAKAKVRLSERN-----VVELVSKLQALKLLDNDLLHTVSGKEYITQDELKREIESEIQRLGRV 75 
255582083   1 MDAELLELQKQFEFAQQAKSSVRLSERN-----VVELVQKLRELHIIDFDLLHTVSGKEYITPEQLRNEIVVEIKKLGRV 75 
242086689   1 MDAELLELQRQLEAAQSAKSSVRLSERN-----VVELVQKLQERGIIDFDLLHTVSGKEYITSDHLKHEIKMEIKKRGRA 75 
240255517   1 MDDELLELQRQFEFAQQVKSSVRLSDRN-----VVELVQKLQELGVIDFDLLHTVTGKEYITQEQLRNEITREISKLGRV 75 
297852594   1 MDEELLELQRQFEFAQQVNSSSSLSTSDyqmemSSNWFRSYKSSASSNLDLLHTVTGKEYITQEQLKKEIASEISKLGRV 80 
297815786   1 MDDELLELQRQFEFAQQVKSSVRLSDRN-----VVELVQKLQELGVIDFDLLHTVTGKEYITQEQLRNEITREISKLGRV 75 
302798443   1 MDAELRELERLFEAAQQAKPTARLSERS-----VVELVVKLQQLGILDADLLHTVSGKEYITQDRLRQEMEAEINRLGRV 75 
302801412   1 MDAELRELERLFEAAQQAKPTARLSERS-----VVELVVKLQQLGILDADLLHTVSGKEYITQDRLRQEMEAEINRLGRV 75 

225435112  76 SLIDLADFTGVDLYHVENQAQCIVSDDPGLTLIQGEIISDSYWDNVAEEINERLQECSQIALAELAAQLHVGSELLTSML 155
168057465  76 SLVDLSGTLGVELVHCERQAQQIVQNNPSLSLMQGEILSSGYWDSIAEEINESLEVAGQISIVELARRFTVGAELMTNVL 155
255582083  76 SLIDLADVIGVDLYHVEKQAQQVVLDDPGLMLTQGEIISQDYWDNIAEEINERLQECSQIALAEIATQLNVGSELVASML 155
242086689  76 SLVDLSDTLGVDLYHVERQSQKVVSDDPTLMLINGEIMSQSYWDTVTEEINEKLQERSQIALAEIAAQLHIGSELVISIL 155
240255517  76 SVIDLADTIGVDLYHVEKQAQDVVLNDPGLMLVQGEIISQSYWDSIAEEINERLQECSQIAVAELAGQLQVGSELVQSVL 155
297852594  81 SVIDLADTIGVDFISC---AQDVVLSDPELMLVQGEIISQRYSDSIAEEINERLQECSHISVAELAGQLQVGIRVAA--- 154
297815786  76 SVIDLSDTIGVDLYHVEKQAQDVVLNDPGLMLVQGEIISQNYWDSIAEEINERLQECSQIAVAELAGQLQVGSELVQSVL 155
302798443  76 SLVDLASLVGVDLFHCERQADQIVSSSPELMLVQGEVVSTKYWDNLAEEVNETLQEASQVSLGELARRYGVGAELLTGML 155
302801412  76 SLVDLASLVGVDLFHCERQADQIVSSSPELMLVQGEVVSTKYWDNLAEEVNETLQEASQVSLGELARRYGVGAELLTGML 155

225435112 156 ELRMGTMVKGRLEGGQLYTPVYVARVSSMVRGAARGITVPTNLSALWSSLQQLLQEMNGS--GGVAVEGSFFQSLFNGLV 233
168057465 156 SARLGTSIHGKLEGGQLYTPAFVARIRATVRGAVRAIMVPTSVSTLSSFLQQQMREVDEGpiTKVTADGGLFQSVLNQLI 235
255582083 156 EARLGKLVKGRLEGGQLYTPAYVARVSAMVRGAARAITVPTNLSVLWGTLQQLLQEMDGA--GGVVVENSFFQSLFNGLV 233
242086689 156 EPRLGTIVKGRLEGGQLYTPAYVSRITAMVRGAARGITVPTNLPSVWNSLQQQLHEMHGA--SGVSVEGSFFQSIFNGLL 233
240255517 156 EPRLGTLVKARLEGGQLYTPAYVERVTAMVRGASRGIFVPSNLSALWAPLQQLVQETNGA--SGVAVENSFFQSIFNRLL 233
297852594 155 -------VKARLEGGQLYTPAYVARVTAMVRGASRGIFVPSNLSFV----------------VDAVASNSFFHSIFDRLL 211
297815786 156 EPRLGTLVKARLEGGQLYTPAYVERVTAMVRGASRGIFVPSNLSALWAPLQQLVQEMNGA--SGVAVENSFFQSIFNRLL 233
302798443 156 SSRIGTIIHAKLEGGQLYTPAYVARVKATVRGALRAITVPTSLQSVWNLLQGLLRDRDDG--GNVTGEHSLFHMVLNELV 233
302801412 156 SSRIGTIIHAKLEGGQLYTPAYVARVKATVRGALRAITVPTSLQSVWNLLQGLLRDRDDG--GNVTGEHSLFHMVLNELV 233

225435112 234 KEGEILGSLRAG-VHWTPTVFAIAQKESIDSFFSQNSFISYEVLLKLGIPQPLQYLQSRYPDGIPLVTIFVHPSMIEMLD 312
168057465 236 ADGEVKGSLRGGnAVYTPAVFAGAQRGSVEAFFSQNGYITFDTLRKLNVPQPKQYLQEMYKDGVALEDVFVHSSLISQLD 315
255582083 234 KEGEVLGSLRAG-VHWTPTVFATAQKECIDSFFSQNSFISYDTLNKLGISQPIQFLQSRYAEGIPLVTAFAHPSLIEMLD 312
242086689 234 KDGAVLGSVRAG-GQWTPAVFAHAQKESVDAFFSQNSYIGYDVLQKLAIPQPKQFLEARYPDGIALDAVFVHPSVVDMLD 312
240255517 234 KEEEMLGSLRAG-THWTPSAFATAQKECVDSSFSQNSYISYESMQKLGISQAVQFLQSRYPDGTPLAAVFIHSSMIEMLD 312
297852594 212 KEEEMLGSLRAG-THWTPSVFAVAQKECVDSFFSQNSYIPYETMQKLGISL-KPFSSYRYPDGKPLAAVFIHSSMIEMLD 289
297815786 234 KEEEMLGSLRAG-THWTPSAFAIAQKECVDSSFSQNSYISYESMQKLGISQAVQFLQSRYPDGTPLAAVFIHSSMIEMLD 312
302798443 234 AEEAVKGTLRG--SIWTPAVFAHSQRESVEAFYSQNSYITYDALQKLNISQPRQYLQTKYPEGIALDNVFVHNSFISLLD 311
302801412 234 AEEAVKGTLRG--SVWTPAVFAHSQRESVEAFYSQNSYITYDALQKLNISQPRQYLQTKYPEGIALDNVFVHNSFISLLD 311

225435112 313 TSAEDAIEHGSWINSLSILPASFGAQDASKILSLCPSVKLALKSNKALILGETYVFSNGFIKDVFDHm---eKEMETFSL 389
168057465 316 AAAEEAIAGKSWFDVLPLVPSSIGPSDAEKLVVLCPTVQKALKDGTAVILADTCVLSATFVKKRVEN-----KKFNKVST 390
255582083 313 AAVEDAVERGSWIDSLSVLPTSFGSQDASKLLSVCPSVQSALKGTKGIVLGDSYIFSNDFVKSIYDRm---eKEMDAFSL 389
242086689 313 TAVGDAIENGHWIDSLSVLPSYISGPDATKILSICPSLQKAIKSSKAVVFGESCVFSNMFIKSIFDRl---eKDMDSFGI 389
240255517 313 SATEDAIEQNSWIDSLSVLPSSFTSQDANKMLLLCPSVQSALKAEKALILGESYVLSSGFIKGIYDQi---eKEADAFSI 389
297852594 290 STTEDAIEQNSWIDSLSVLPASFTSQDANKMLLLCPSVQSALKAEKALILGESYVLSNGFIKGIYDQi---eKEAEAFSI 366
297815786 313 SATEDVIEQNSWIDSLSVLPSSFTSQDAKKMLLLCPSVQSALKAEKALILGESYILSSGFIKGIYDQi---eKEAEAFSI 389
302798443 312 SAAEESVKGGGWLDALDVLPSTFGCSDSGKLLLLCPFVQRALKDSTATLVAETCIVGTGFVKALLEKfqnmlREIQDKTF 391
302801412 312 SAAEESVKGGGWLDALDVLPSTFGCSDSGKLLLLCPFVQRALKDSTATLVAETCIVGTGFVKALLEKfqnmlREIQDKTF 391

225435112 390 SGPSMGMVfedlhsvkevkaghdssRFTELNEPSNESGsnkqSIEKGSKRKKGKTTgntkTSAAESGPDNQEYVPTKSKK 469
168057465 391 QSLSEGVT-----------------GISTTDTGTEDAS----GQLKGGRRKKGNQS----NGATRPAPEIEAVVPKEGKG 445
255582083 390 SGSSGAVLsdglslvrdvkfrndsgGSSQLSETGNEK-----------RKKKGKSA----GTKATDIPEDEDYIPTKSKK 454
242086689 390 RHSVGQGRplnanlgs-ehktgcgqYSDTKDLGDNDTSstgvSSDRGSKKKRGKGTgstkGGSLEKDDDNEESIPIKGKK 468
240255517 390 QASTATLI-----------------HPSSKSSESTESIp--aNTDKGSKKKKGKSAst-kAATVETVPDDEEDARPKSKR 449
297852594 367 QASNASLI-----------------DHSSKSSESVESIpastNTDKGSKKKKGKSVsm-kTATNETVSDDEEDARPKSKR 428
297815786 390 QASTASLI-----------------DPSSKSSESTESIp--aNTEKGSKKKKGKSVsm-kAATVETVPDDEEDARPKSKR 449
302798443 392 STLEVKLE-----------------AEPEPELDENETKpfasRSKKNDKKQKD-----------NSIRKEEENEEKSGKS 443
302801412 392 STLEVKLE-----------------AEPEPELDENETKpfasRSKKNDKKQKD-----------NSIRKEEENEEKSGKS 443

225435112 470 NQRKGKDTSSLRVSDSKTGSKK-----ESDKMKEDNFSI-PEEWVMQKITKMVPDFEE-QGVD--DPEMILRPLADYLRP 540
168057465 446 KRRAGKSKGEKVSGEAVAGVSKgfksgTGPNSANDEDNIfTVEFLTSKILEWFPDLES-AGIV--EEGILVKALADLLKP 522
255582083 455 NQRKGKDASFQV-SDTKTGGKK-----DLAKMQEDSLNVpSEEWVMQKILTLVPDFEE-QGVD--DLQIILRPLAKYMRP 525
242086689 469 SHRKNKDAGASG--DVKHGGKK-----ASEKIKEESTNIfPDELIEQKVLAAAPELEElGGSD--DSNAPLKLLSSHLRP 539
240255517 450 NQKKGRDSSSSQKLDSKAGGKK-----ESVKAQESNNIIpPDEWVMKKIVDSVPEFED-DGTE--NPDSILKHLADHMKP 521
297852594 429 NQKKGRGSSKL---DSKAGGKK-----ESVKAQEGNNFIpPDEWVMKKIVDFVPEFED-EGME--NPDSILKHLADLMRP 497
297815786 450 NQKKGRDSSSSQKLDSKAGGKK-----ESVKAQENNNFIpPDEWVMKKIVDSVPEFED-DGTE--NPDSILKHLADHMKP 521
302798443 444 KKKTARHKSSKTPSVKEAVPSK-----ARKGSPADEMDLlAEEKLSKKIIEWYPDLEA-AGTEdgDTGVLAKCLADQLRP 517
302801412 444 KKKTARHKSSKTPSVKEAVPSK-----ARKGSPADEMDLlAEEKLSKKIIEWYPDLEA-DGTEdgDTGVLAKCLADQLRP 517

225435112 541 MLLNSWKERRRALFTENAERMKRVLDNLQKKLDESFLNMQ----LYVKALDLFEDDQSTSVILHKHLLRTTAASIVDMVL 616
168057465 523 KVMAAAIHAKQALFSAQAEDRRRRLDTLQHKIDEASTPFFclpwLFSKALNLFEDNEKTGVLLHRHLLRTTGAELVDLFL 602
255582083 526 MLINCLKERRKALFTENTEKVKRLLDNLQKELDEPFLNMQ----LYEKALDLFEDDQSTSVILHRHLLRTIAASIADTLF 601
242086689 540 MLVDSWTKKRNTMLSGNAERRRRLLDNLQKQIDEAVLDMQ----LYEKALDVFEDDPSTSGILHKHLLRSMGTPIVDKVL 615
240255517 522 MLINSLKERRKKIFTENADRMRRLIDDLQKKLDESFLNMQ----LYEKALDLFEDDQSTAVVLHRHLLRTTAATIADTLL 597
297852594 498 MLINSLKERRKKIFTENADRMKRLMENLQKKLDESFLNMQ----LYEKALELFEDDQSTSVVLHRHLLRTTTATIADTLL 573
297815786 522 MLINSLKERRKKIFSENADRMRRLIDDLQKKLDESFLNMQ----LYEKALELFEDDQSNSVVLHRHLLRTTAATIADTLL 597
302798443 518 QLISYMTSLKRAYLGAKTEERRKRIDALQRKIDEDYANLQ----LFSKAIELFEDDKGMEAVLHKHLLRSTASEITDVFL 593
302801412 518 QLISYMTSLKRAYLGANTEERRKRIDALQRKIDEDYANLQ----LFSKAIELFEDDKGMEAVLHKHLLRSTASEIADVFL 593

225435112 617 LNLDVHNKlkNGIEVEESQNSESISVTSGERIALAKSLPG-SLSARALALVEALEGKRVEIFMTSLDEMAEDSGLLLKKL 695
168057465 603 IAQAEDDI--DDKEVGITATKETELLNTSQRTAMAKSLPArNLSSKALELVESLEAKNVDAFERTFEAAVTESGLRVKKL 680
255582083 602 HNLDKHNKmkNGIEVEDSQSLESITFNSAERIALAKSFPG-SLSKKAITVIEALEGKRVEVFMISLREIAEESGLLLKKL 680
242086689 616 ITLDKDSKlkNGMEVEDSE--DHVQLSTADRSSLAKDLPG-ALSLKAQALIEALEGKRFDSFMDALRDVLEESGLTFKKL 692
240255517 598 HGLDIHNKmkNGTEVEESKTQDLVLLDSSERTALAKNLNG-SLSKKALALVEALEGKRVDTFMVTFRDLAEESGLVLKKL 676
297852594 574 HDLDILNKlkNGTEVGDSKTQDTVLLDSSERTALICKFDH--------------YSNRVDAFMTTFRDLAEESGLVLKKL 639
297815786 598 HGLDIHNKlkNGTEVGESKTQDQVLLDSSERTALAKNLNG-SLSKKALALVEALEGKRVDTFMITFRDLAEESGLVLKKL 676
302798443 594 ETQALEHRieNA---ESAGAQPCKPFSMAVRMSLAKNLPE-PLSSAATEMVASLEGKNIGAFDSALEASVTESGLRVRKL 669
302801412 594 ETQALEHRieNA---ESAGAQPCKPFSMAVRMSLAKNLPE-PLSSAATEMVASLEGKNIGAFDSALEASVTESGLRVRKL 669

225435112 696 DKKLERTLLHSYRK------------------DLTSQVSAESDPVSLLPKVVSLLYVQIHNRALQAPGRAISIAVSRLKD 757
168057465 681 DKKSERALMFSYRK------------------GLTSQVGDETDSVALLPKVVGLLFVQVHSRALQAPGRAMLAAIMRLKG 742
255582083 681 DKKLERTLLHSYRK------------------DLTAQVSAETDPVALLPKVVSLLYIQIHNKALQAPGRAISFAVSRLKD 742
242086689 693 DKRLERTMLHSYRK------------------DLTAQVSSENDPVSFLPKVVALLFLQAYNKALQAPGRAVGAVITLLKD 754
240255517 677 DKKLERTLLHSYRK------------------DLISQVSTESDPIALLAKVVSLLFIKIHNKALQAPGRAIAAAISHLKE 738
297852594 640 DKELERTLLHAYGKcmildhcfsslgdvlctwDLTSQVSTESDPVALLAKVVSLLYIKAHNKALQAPGRAIAAAISHLKD 719
297815786 677 DKKLERTLLHSYRK------------------DLISQVSTESDPVALLAKVVSLLFIKVHNKALQAPGRAIAAAISHLKD 738
302798443 670 DKKGERSLFFAYRK------------------NLSEQVDQEQDPIALLPKVVALLYVQVHGRALQAPGRAMSSAVARLKS 731
302801412 670 DKKGERSLFFAYRK------------------SLSEQVNQEQDPIALLPKVVALLYVQVHGRALQAPGRAMSSAVSRLKS 731

225435112 758 KLDDSAYNILMDYHTATVTLLALMSAATDDEQDCTADRILSKREl-LESLMP--SLKGLVLGTSQS 820
168057465 743 SIPDELFEVLMAYHNGTVQLLSLQTSANLEETDASNETITKQEE--LKTLIP--QLKSMVLPSSSS 804
255582083 743 KLDDSAYKILTDYQSATVTLLSLISASTGDEEDCTSDRILNKREf-LENLMP--ALKGLVLSS--- 802
242086689 755 KLPASTYKVLADYHSTTVKLLALQAAATDDEEDCTSDRTRERKEdlEERLMP--ELKSLVLGTNKE 818
240255517 739 KLDESAYKTLTDYQTATVTLLALMSASSGEEHDCSADRILTKREl-LESQMP--LLRTLVLGDSQP 801
297852594 720 KLDESAYKTLTDYQTATVTLLALMSASTGEEHDCSSDRILTKREl-LESQMP--VLRSLVLGDSQP 782
297815786 739 KLDESAYKTLTDYQTATVTLLALMSASSGEEHDCSADRILTKREf-LESQMP--LLRTLVLGDSQP 801
302798443 732 AIPDKAFSTLDQYLSETVSLLSSSAAD-------------------VRYNLPagPLSHTAVPAGFQ 778
302801412 732 AIPDKAFSTLDQYLSETVSLLSSSATD-------------------VRYNLPagPLSHTAVPAGFQ 778