Conserved Protein Domain Family
PLN02913

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PLN02913: PLN02913 
dihydrofolate synthetase
Statistics
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PSSM-Id: 178501
Aligned: 8 rows
Threshold Bit Score: 782.853
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PLN02913 is classified as a model that may span more than one domain.
PLN02913 is the only member of the superfamily cl31951
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
242083760  21 LERKGITARRGVSVMAGGGEAEEGPLGGFLEYMERLRNYERSGVPRGAGTDSDDGFDLGRMRRLLRRLGDPHTHFPAVHI 100
30693806   20 MRRISAANLISNRNLSTISSTEDPELRDFVGFLESLKNYEKSGVPKGAGTDSDDGFDLGRMKRLMLRLRNPHYKYKVVHV 99 
225462719   1 MKIFRVVSHKRTLLGFKRSFSTEPELKDFLNYLDNLKNYEKCGVPKDAGTDSSHGFDLGRMNRLMDRLGNPETGFKAVHI 80 
224116906   1 -----------MARFLFSKYTEEPEPKEFIDYLDSLKNYEKLGVPKDAGTDSDDGLDLGRMRRLMDRLGNPQSKFKAVHV 69 
255545058  17 IEADSGGVVSRWRKQLFSTLSEAAELNDFMNYLDSLNNFEKSGVPKGAGTDSDEGFDLGRMRRLMDRLGNPHSKFKAVHI 96 
297805500  20 IRRISSANLTSNRNLSTISSTEDPELRDFVGFLESLKNYEKSGVPKGAGTDSGDGFDLSRMKRLMLRLHNPHSKYKVVHV 99 
302771061   1 -----------------------MAEGGALRFLQQLSDLERLGVPKDAGTDTSKGFDLGRMRRLVSSLGNPLSKFPVVHV 57 
302816635   1 -----------------------MAEGGALRFLQQLRDLERLGVPKDAGTDTSKGFDLGRMRRLVSSLGNPLSKFPVVHV 57 
242083760 101 AGTKGKGSTAAFLSNIMRAQGYNVGCYSSPHLLTIRERISVGndGGPVPVGLLSDLFDEAKEAIDEAIESENGSLTHFEV 180
30693806  100 AGTKGKGSTSAFLSNILRAGGYSVGCYSSPHILSIKERISCN--GEPVSASTLNDLFYSVKPILEQSIQEENGSLSHFEI 177
225462719  81 AGTKGKGSTAAFLANILRTEGYAVGCYTSPHVRTIRERISLGklGEPVSAKALNCLFHRIKPILDEAVALENGRLSHFEI 160
224116906  70 AGTKGKGSTAAYLSNILRAEGYSVGCYTSPHMMSIRERISLGqsGNPVSTKTLNKLFHMIKPKLDEAIQLENGSLTHFEV 149
255545058  97 AGTKGKGSTAAFLSNILRAQGYSVGCYTSPHIVTIRERMSIGklGKPVSPMALNSHFHQIRQKLDEAIQLENGCLSHFEV 176
297805500 100 AGTKGKGSTSAFVSNILRAGGYSVGCYSSPHILSIKERISCN--GEPVSASTLNDHFYSIKPILEQSIQEENGSLSHFEI 177
302771061  58 AGTKGKGSTVAFLSSILRAAGFSVGTYTSPHLRSIHERICV---GKPISTNGLDDLFWGVRESLLKVIEAENHTLTHFEV 134
302816635  58 AGTKGKGSTVAFLSSILRAAGFSVGTYTSPHLRSIHERICV---GKPISTNGLDDLFWGVRESLLKVIEAENHTLTHFEV 134
242083760 181 FTALSFLLFSQENVDIAIIEAGLGGARDATNVIRSTELAASVITTVGREHLAALGGSLQSIAIAKSGIIKQGRPVVIGGP 260
30693806  178 LTGIAFSLFEKENVDIAVIEAGLGGARDATNVIESSNLAASVITTIGEEHMAALGGSLESIAEAKSGIIKHGRPVVLGGP 257
225462719 161 LTAMAFKLFAQENVDVAVIEAGLGGARDATNIISSSGLAAAVITTIGEEHLAALGGSLESIAMAKSGIIKQGCPLVLGGP 240
224116906 150 LTATAFTLMAEEKVDIAVIEAGLGGARDATNILCSSELAASVITTIGEEHLAALGGSLESIAVAKSGIIKYGRPVVLGGP 229
255545058 177 LTAIAFSLFAQENVDIAIIEAGLGGARDATNILCSSQLATSIITTIGEEHLMALGGSLESIAMAKAGIIKRGRPLILGGP 256
297805500 178 LTGIAFSLFEKENVDIAVIEAGLGGARDATNVIESSNLAASVITTIGEEHMAALGGSLESIAEAKSGIIKHGRPVVLGGP 257
302771061 135 FTALAFKYFAQESVDIAVVEAGLGGARDATNVIDSEGLAASVIVSIGEEHLEALGGSLESVVLAKAGIIKERRPVVLSRQ 214
302816635 135 FTALAFKYFAQESVDIAVVEAGLGGARDATNVIDSEGLAASVIVSIGEEHLEALGGSLETVALAKAGIIKERRPVVLSRQ 214
242083760 261 FAADIEQIIRDRAFLTQSPVISACDPGVKSFTKCIDWDNG-KPYQRCYINIKISNDVPLSIEMQDINLQLLGDHQRQNAV 339
30693806  258 FLPHIEGILRSKAASVSSSVILASNIGSSSSIKGIINKNGiGLCQSCDIVIQNEKDDQPIVELSDVNLRMLGHHQLQNAV 337
225462719 241 FLPHIEHIFLDKASSMCSPVVSASGPGNRSAVKGVSKSNG-KPFQSCDIVIEVERDFKLFIELFDVKLQMLGIHQLQNAA 319
224116906 230 FLSHVDRILRDKASVMCSPVVSASDAGIRTSIKGLIILDG-RPCQLSDIMIQVERDFPLFIELSDVKLRMLGRHQLHNAS 308
255545058 257 FLPDIERILRDKASLMLAPVVSASDSGIRTTIKGLSMFDG-RHCQLCDIKIRVKKALNLFIELSDLEMRMLGSHQLQNAA 335
297805500 258 FLPHIEGILRSKAASMLSSVILASNIGSSSSIKGIINKNGfGLCQSCDIVIQNEKDDKPIVELSDVNLRMLGHHQLQNAV 337
302771061 215 VSPVAESIIRTQASAKNAPVFSAFGKNVHGIIKSIRTDES-DCFQVCDMRIRCAGEN---LFLDNCRMRMFGSHQVDNAL 290
302816635 215 VSPVAESIIRTQASARNAPVFSAFGKDVHGFIKSIRTDES-DCFQVCNMRIRCAGED---LFLDNCRMRMFGSHQVDNAL 290
242083760 340 TAACAALCLRSEGW-DISDASIQAGLEETQLPGRSQFLTAEEASVLGLNGAsTVLIDGAHTEESAKALSGVIKTVRPEGP 418
30693806  338 TATCVSLCLRDQGCgRVTDEAIRIGLENTRLLGRSQFLTPKEAETLLLPGA-TVLLDGAHTKESARALKEMIKKDFPEKR 416
225462719 320 TATCVALCLRDKGW-RISDESIHAGLEHAYLLGRSQFLTSTEAETLGLPGA-TIMLDGAHTKESAKALVDTIQMTFPEAR 397
224116906 309 SAACVALCLRDQGC-RISDRSIRAGLENTFLLGRSQFLSSKETEVLGLPGA-TILLDGAHTKDSAKALVDTVRMAFPDAR 386
255545058 336 TAACAALCLRDQGW-KISDASIRLGLENTCLLGRSQFLASKDAEVLGVPGA-TILLDGAHTKESAKALVDTVRLTFPEAR 413
297805500 338 TATCVSLCLRDQGCgRVTDEAIRIGLENTRLLGRSQFLTPKEAETLQLPGA-TVLLDGAHTKESARALKDMIKKDFAEKR 416
302771061 291 TAVCAALSLRVEGGwRIPDAAFQTGLEQTNILGRFQILTHEQVKSLGFTSA-RVILDGAHTPGSAAALGTTLKTAFPSRP 369
302816635 291 TAICAALSLRVEGW-RIPDAAFQTGLEQTNILGRFQILTHEQVKSLGFTST-RVILDGAHTPGSAAALGTTLKTAFPSRP 368
242083760 419 LALVVGMATDKEHLAFAEQLLSGQTPDVVLLTEASIAGGTSRAMPASSLKEVWIAAARDHGIECVdiggvsgaeapehig 498
30693806  417 LVFVVAMASDKDHVSFAKELLSGLKPEAVILTEADIGGGKIRSTESSVLKESWIKAADELGSRSMe-------------- 482
225462719 398 LALIVAMASDKDHMAFAREFLSGGQLEAVFLTEVNIAGAKSRTTSASMLRDCWIQASKELGINTL--------------- 462
224116906 387 VALVVAMASDKDHLAFAREFLSGLQLEAVFLTEADIAGGKSRTTSASLLMDCWIQASEELGINTL--------------- 451
255545058 414 LALIVAMASDKDHLAFAGEFLLDKKLEAVFLTEAEIAGGKSRTTAAPLLRDYWVQACEELGINTLhdgmaeyrellene- 492
297805500 417 IVFVIAMASDKDHVSFAKELLTGLKPEVVILTEADIGGAKIRSTSSSVLKESWIKAADELGSGSMe-------------- 482
302771061 370 LILVTAMALDKDHLKFASAFSDDARPTLVVVTTADVAGSSVRSATTEALAGAWSKVKPEIAVEIS--------------- 434
302816635 369 LILVTAMALDKDHLKFASAFSDDARPTLVVVTTADVAGSSVRSATTEALAEAWSKVKPEIAVEIS--------------- 433
242083760 499 dllgspssssgrkppmvigcQDEGPFSSNLIIAASRLLEKSRGRAHPGLICVTGSLHLVGAVLQQLGR 566
30693806  483 --------------------ASENKTVLGSLKLAYKILSDDTTSSDSGMVIVTGSLHIVSSVLASLQH 530
225462719 463 --------------------LAAENSLLVSLRVGNQILR-ARTRDQTSIIVITGSLHIVSTVLSSLLG 509
224116906 452 ---------------------------------HDGMEKNRELLEENKIILATRNHRRLP-------- 478
255545058 493 -------fihserhlggkiiLATNNSLEISLRMASEFLR-GRTGNQSSVLVVTGSLHIVSSVLARLHG 552
297805500 483 --------------------ASENKTVLDSLKLAYKILSDDRSSSDSGMVIATGSLHIVSSVLASLQQ 530
302771061 435 ----------------------------KSVVDALATARKAADLDPGSVVCVTGSLHLVSAVLNLVSA 474
302816635 434 ----------------------------KSVVDALATARKAADLDPGSVVCVTGSLHLVSAVLNLIKK 473
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