224115854    1 MNVNTCIQPPQFLPLSPFYQQRFHLFTQKPQSLKPTKKSCYFSTtac-----------dnSFKGGLFRVQKGRIRCSVSE 69  
15233478     6 QILQIRSDPFVLSHCCRHTRLTSSLTLQSPLKQPFSCLPFRWRR----------------SYRGGVRSSTTETHGSKKEA 69  
168025691    1 ------------------------------------------------------------------MNRLNDSPFSLPLQ 14  
219124456    4 FSTPTRTHPTSAVSFVSVVVVVVSMILRVSTAFVPS------------------------LRRTGYPASGRVRPFLATTS 59  
225444321    6 LHIQLLQPPPLHRHALSFSAYSRRKFTTTSSATTVAVGKSYFGN----------------GVWNGVSRSIRNSATKELSE 69  
242052287   14 LPLQLQARPPAVTAGHHRRRHRLLPVRR--------------------------------------SRPLLRARCCASAA 55  
223998058    1 ---MMIAQRVLASSAFRAPSSSLKNNLVVRHRSAAASSS---------------------AFVSSDRRPWTTNTHRSMST 56  
255554793    7 MLTQFLPSSPFHHRQFHFTKTTLSFKPAKNSVFNLN------------------------------YGGFEFKSSRVRSS 56  
297809613    5 QILQFRSDPFVLSHCCRHTHLTSSLTLQSPLKQPFSGLRFRWRR----------------SNHGGVRSSTTEAQSNKEEA 68  
302834659   14 LSSRTIRPGLAQSLLLRPCSLRCKAFSVLSPFQTRGPAASGPIH----------------HRGLQPTKAVEAVAPAAPSP 77  
303280587   14 AAVAARAPRSSASARATTTTTRVASMSSRARLGSLALATWSRCArpavapkraaarvvasSSSRGASSSSARDAVASDVA 93  

224115854   70 VEEQKEKQLQVVKRAYPFHEIEPKWQSYWEKNQTFRTP---DEVDTSKPKFYVLDMFPYP-----SGAGLHVGHPLGYTA 141 
15233478    70 LVSETATTSIELKRVYPFHEIEPKWQRYWEDNRIFRTP---DDVDTSKPKFYVLDMFPYP-----SGAGLHVGHPLGYTA 141 
168025691   15 LDQEKGLETPQKIRGYPFPEIEARWQQYWEDNQTFRTP---DVVDTTKPKYYVLDMFPYP-----SGAGLHVGHPEGYTA 86  
219124456   60 HRSTREVSETAAPVHYPFAKVESKWQAYWDENETFQTP----TRDLSKPKKYVLDMFPYP-----SGAGLHVGHPEGYTA 130 
225444321   70 VEGQDRKE--PIRRAYPFHEIEPRWQRFWEENRTFRTP---DDVDTSKPKFYVLDMFPYP-----SGAGLHVGHPLGYTA 139 
242052287   56 AAADTGKAQAAARRAYPFDEIEPRWQRHWEEHRTFRTPdigDGLDTSKPKCYILDMFPYP-----SGAGLHVGHPLGYTA 130 
223998058   57 ETETITSTEPQQQTGYPFATIEPKWQSYWKENNTFKTP---ELTKSTKKKKYVLDMFPYP-----SGAGLHVGHPEGYTA 128 
255554793   57 VNEEQEQKQPMVKKAYPFHEIEPKWQRYWEDNHTFRTP---DEIDTSKPKFYVLDMFPYP-----SGSGLHVGHPLGYTA 128 
297809613   69 LVSETATTTIELKRVYPFHEIEPKWQRYWEDNRTFRTP---DDVDTSKPKFYVLDMFPYP-----SGAGLHVGHPLGYTA 140 
302834659   78 ASATQADAKSAASQAYPFTEIEAKWQAYWEQNQTFHTP---DQVDTSKPKYYVLDMFPYP-----SGAGLHVGHPEGYTA 149 
303280587   94 ETSSDAESTAARSGGYPFADIEARWQKHWAENKTFKTP---DQIDTTKPKFYALDMFPYPrrvvaAGAGLHVGHPEGYTA 170 

224115854  142 TDILARLKRMQGYNVLHPMGWDAFGLPAEQYAIETGTHPKITTLRNINRFlSLQLKSLGLSYDWDREISTTEPQ------ 215 
15233478   142 TDILARLRRMQGYNVLHPMGWDAFGLPAEQYAIETGTHPKTTTLKNIDRF-RLQLKSLGFSYDWDRELSTTEPD------ 214 
168025691   87 TDIMARYKRMRGFNVLHPMGWDAFGLPAEQYAIQTGTHPRETTLKNIDRF-RSQLKSLGFSYDWQREISTTEPD------ 159 
219124456  131 SDVMSRYWRMKGYDVLHPIGWDSFGLPAEQFAIQTGTKPASTTKKNIANF-KRQLKSLGFSYDWDREIATTDRG------ 203 
225444321  140 TDILARFKRMQGYNVLHPMGWDAFGLPAEQYAIETGTHPKITTTRNIARF-RSQLKSLGFSYDWEREISTIEPE------ 212 
242052287  131 TDILSRFKRMKGFNVLHPMGWDAFGLPAEQYAIETGTHPKITTERNIGRF-RTQLKSLGFSYDWDREISTTEPA------ 203 
223998058  129 SDVMSRYWRMTQHDVLHPIGWDSFGLPAEQFAINTGTHPELTTAKNIANF-KRQLQMLGFSYDWEKELATTDVN------ 201 
255554793  129 TDILARFRRMQGYNVLHPMGWDAFGLPAEQYAIETGTHPKITTLRNINRF-RSQLKSLGFSYDWDREISTIEPE------ 201 
297809613  141 TDILARLRRMQGYNVLHPMGWDAFGLPAEQYAIETGTHPKTTTLKNIDRF-RLQLKSLGFSYDWDRELSTTEPD------ 213 
302834659  150 TDILARYKRMRGFNVLHPMGWDAFGLPAEQYALQTGTHPAVTTQRNVTRF-RQQLKALGFSYDWSREISTTDPE------ 222 
303280587  171 TDIVARYKRMTGHNVLHPMGWDAFGLPAEQYAIETGTHPRDTTVANVARF-REQLQSLGFSYDWDREVATCEPQvrsihw 249 

224115854  216 --------YYKWTQWIFLQLLKRGLAYQAEVPVNWCPALGTVLANEEVVDGVSERGGHPVIRKPMRQWMLKITAYADR-- 285 
15233478   215 --------YYKWTQWIFLQLYKKGLAYQAEVPVNWCPALGTVLANEEVVDGVSERGGHPVIRKPMRQWMLKITAYADR-- 284 
168025691  160 --------YYKWTQWIFLQLFKRGLAYEAEVAVNWCPALGTVLSNEEVIDGLSERGSHPVIRKPMRQWMLKITQYADR-- 229 
219124456  204 --------YVQWTQWIFLQLFRKGLAEQSEVSVNWCPALGTVLANEEVINGLSERGDHPVERVPLRQWVLRITDYADR-- 273 
225444321  213 --------YYKWTQWIFLQLLKRGLAYQAEVPVNWCPALGTVLANEEVVDGVSERGGHPVIRKPMRQWILKITAYADR-- 282 
242052287  204 --------YYKWTQWIFLQLLKRGLAYQAEVPVNWCPALGTVLANEEVVDGVSERGGYPVIRKPMRQWMLRITSYADR-- 273 
223998058  202 --------YVKWTQWIFLQLYKKGLAKQSEVSVNWCPALGTVLANEEVINGLSERGDHPVVRLPLRQWVLKITEYADR-- 271 
255554793  202 --------YYKWTQWIFLQLLKRGLAYQAEVPVNWCPALGTVLANEEVVDGLSERGGHPVIRKPMRQWMLRITAYADR-- 271 
297809613  214 --------YYKWTQWIFLQLYKRGLAYQAEVPVNWCPALGTVLANEEVVDGVSERGGHPVIRKPMRQWMLKITAYADR-- 283 
302834659  223 --------YYRPR-WQAVSL-----------------------------KCVSERGGYPVVRMPMKQWMLRITAYAER-- 262 
303280587  250 fpydsvgvYYKWTQWIFLKLLEKGLAYRAEVPVNWCPALGTVLANEEVIDGLSERGNHPVIRKPMKQWMLKITAYGDRll 329 

224115854  286 --------------------------------------------------------------LLEDLDDLDWPESVKEMQ 303 
15233478   285 --------------------------------------------------------------LLEDLDELEWPESIKEMQ 302 
168025691  230 --------------------------------------------------------------LVEDLDDLDWPESIKDMQ 247 
219124456  274 --------------------------------------------------------------LEAGLEGLEWPAGTMTAQ 291 
225444321  283 --------------------------------------------------------------LLEDLDDLNWPESVKEMQ 300 
242052287  274 --------------------------------------------------------------LLEDLNDLDWPESIKEMQ 291 
223998058  272 --------------------------------------------------------------LQQGLDGLDWPSGTMVAQ 289 
255554793  272 --------------------------------------------------------------LLEDLDDLDWPESVKDMQ 289 
297809613  284 --------------------------------------------------------------LLEDLDELEWPESIKEMQ 301 
302834659  263 --------------------------------------------------------------LLSDLELLDWPDSIKDMQ 280 
303280587  330 rrvvltlvpirprsrgerrslrtfagvslrpflalnhrhrrlstppdafqlhpdffasygttLISDLDDLDWPESIKEMQ 409 

224115854  304 RNWIGRSEGAELEFCVLDGDGKE--RDIKITVYTTRPDTVFGATYLVVAPEHSLLPSLMSLSQRESVEEYKDLASRKSDL 381 
15233478   303 RNWIGRSEGAELNFSILDGEGRE--TDKEITVYTTRPDTLFGATYMVVAPEHQLLSYFVTAEQKQQVEEYKDFASRKSDL 380 
168025691  248 RNWIGRSEGAELGFPILDGNGTL--RDLNVRVYTTRPDTLCGATYLVVGPEHPLLQQITSDDQKQAVAEYVEAASKKTDL 325 
219124456  292 KQWIGKSIGCNIDFGVDQW------PDETISVFTTRADTLMGVTYVTLAPEHPLVASLATDEQKDVVNAYVKTTSSRSDL 365 
225444321  301 RNWIGRSEGAEVEFCVLNSDGQE--SDNKITVYTTRPDTIFGATYLVLAPEHFLLSSLVSTVQSKYVEEYKEIASRKSDL 378 
242052287  292 RNWIGRSKGAELVFSAVDQEGHD--LGATLLVYTTRPDTIFGATYLVVAPEHVLLSSLTSEEQREHVEEYRELSARKSEL 369 
223998058  290 EQWIGKSVGTEIDFKVDGM------EEEKVKVFTTRADTLFGVTYVTLAPEHPLVSSITTPEQKEEVDAYVAATSSRSDL 363 
255554793  290 RNWIGRSEGAEMEFHVLDDDGKE--RDINLTVYTTRPDTIFGATYLVVAPEHSLLPSLVSLSQSKNVEEYKDLASRKSDL 367 
297809613  302 RNWIGRSEGAELNFSILDGEGRE--TDKKITVYTTRPDTLFGATYMVVAPEHHLLSYFVTAEQKQQVEEYKDFASRKSDL 379 
302834659  281 RNWIGRSEGAEVRFQLSAGPGASlpADTHITVFTTRPDTLFGATYLVVAPEHPLVGQLATSEHAAAVHSYVEAASRKSDL 360 
303280587  410 RNWIGRSEGAQLAFEVPGVTG----DENKLEVYTTRPDTLFGATYLVVAPEHPLVGALSTAEQKAAVDAYVDAASRKSDL 485 

224115854  382 ERTELQKEKTGVFSGCYAQNPANGEAIPIWVADYVLGSYGTGAIMAVPAHDTRDYEFATKYDIPIRWVVKPD-DDDFSDS 460 
15233478   381 ERTELQKDKTGVFTGCYAKNPANGDAIPIWVADYVLASYGTGAIMAVPAHDTRDNEFALKYNIPIKWVVRNE-ANSSDDA 459 
168025691  326 ERTELQKVKTGVFTGTYARNPATAEAIPIWVADYVLGGYGTGAIMAVPAHDSRDFEFAKAFDLPMRLVVSPN-DGKEWDQ 404 
219124456  366 DRTS-AKEKTGVFTGAYAIHPISGDKVPIWIGDYVLGSYGTGAVMAVPAHDARDFEFAQKFGLDIKWVVEPA-SGELVSK 443 
225444321  379 ERTELQKEKTGVFSGAYARNPANGEAIPIWVADYVLGSYGTGAIMAVPAHDTRDHEFALKYDIPICWVVTPN-DINGDDF 457 
242052287  370 ERTDLQKEKTGVFSGSYAKNPATGEIIPIWVADYVLGSYGTGAIMAVPAHDSRDHEFAVKYELPIIKVVSPP-NGNCDPV 448 
223998058  364 DRTS-NKEKTGVFTGGYAIHPLTNEKIPIWIGDYVLGSYGTGAVMAVPAHDDRDFEFAQKFGLEVKWVVGSGkEGDELSK 442 
255554793  368 ERTELQKEKTGVFSGCYARNPANGEAIPIWVADYVLGSYGTGAIMAVPAHDTRDYEFATAYDIPIRWVVKAD-DEGCSDS 446 
297809613  380 ERTELQKDKTGVFTGCYAKNPANGDAIPIWVADYVLASYGTGAIMAVPAHDTRDNEFALKYNIPVKWVVKNE-ANLSDDA 458 
302834659  361 ERTELQKEKTGVDTGSFAINPATGEKVPVWVADYVLGSYGSGAIMAVPGHDVRDHEFAVRFGLPIKQVVAPA-DGG--EV 437 
303280587  486 ERTELAKEKTGVFTGSHAKHPLTGADVPVWVADYVLGTYGTGAIMAVPAHDDRDKEFAETFDLPIVQVVAPPgDENNTDA 565 

224115854  461 GKAYEREGSILNSSSstSGLDINGLHSKVAASKVIEWADTTGNGKKKVNYKLRDWLFARQRYWGEPIPVVFLQD------ 534 
15233478   460 KQVYPGLGIIENSSTleTGLDINQLSSKEAALKVIEWAERTGNGKKKVNYKLRDWLFARQRYWGEPIPILILDE------ 533 
168025691  405 EKAYSGDGKLVNSSY---EIDINGLSTSEAASKVIHWLEQNGFGTKKVNYKLRDWLFARQRYWGEPFPLLLLEN------ 475 
219124456  444 EQAFTEAGRNVNSGA------FDGLTTDEAKKAVTSKLEELNKGGPRITYKLRDWVFSRQRYWGEPIPIYFPVDfpdgid 517 
225444321  458 EKPYPGEGLIINSSSstTGLDINGLSSKVAASKVIEWAEKTVHGKKKVNYKLRDWLFARQRYWGEPIPVSFLDD------ 531 
242052287  449 E-AYEDDGVMINSSSssSGLNINGMLSQDAAKKVIEWVESNGFGKKKVNYKLRDWLFARQRYWGEPFPVSYLDD------ 521 
223998058  443 EKAFTEHGVNVNSGE------FDGLKTAKAKKAITEKLEEISSGGAKITYKLRDWVFSRQRYWGEPIPIYFPVE------ 510 
255554793  447 GMAYAGEGTILNSSNltLGLDINGLSSKAAASKVIEWAEKTGNGKKKVNFKLRDWLFARQRYWGEPIPVVFVED------ 520 
297809613  459 KQVYPGLGIIENSSSseTGLDINQLSSKEAGLKVIEWSERTGNGKKKVNYKLRDWLFARQRYWGEPIPILILDE------ 532 
302834659  438 ELPYTEPGVAVNSSS--SALSIDGQSSEVARGSVVSWLEGAGAGSRQVNYKLRDWLFARQRYWGEPFPLVYPEG------ 509 
303280587  566 DACYSGAGTMINSAC--DALDVNGLDDATAGEKVTAWLTANGVGEKKVNFKLRDWLFARQRYWGEPFPVVYPEG------ 637 

224115854  535 ----------------TGETAPILETDLPLTLPELDDFTPTGTGEPPLAKAVSWVKTTDPSSG-KPAMRETSTMPQWAGS 597 
15233478   534 ----------------SGETIAISESELPLTLPELNDFTPTGTGEPPLSKAVSWVNTVDPSTG-KPAKRETSTMPQWAGS 596 
168025691  476 -----------------GEIKAVPESDLPVTLPEIDEFTPTGTGEPPLAKATSWVNTTDPESG-KPARRETNTMPQWAGS 537 
219124456  518 pttqnpaddnceytirFDQPIPVAEADLPLELPEMDDFQPGDDPAGCLARAKDW--RFFAKDG-KWFSRETNTMPQWAGS 594 
225444321  532 ----------------SGERVPLPETELPLTLPELDDFTPTGTGEPPLSKAVSWVKTTDPLSG-KPARRETSTMPQWAGS 594 
242052287  522 ----------------TNEMVPLSEDELPLTLPELDDFTPTGTGEPPLTKATNWVRTMDPLSG-KPARRETSTMPQWAGS 584 
223998058  511 ----------------FPEGVDPSAADLPLELPEMEDFSPGDDPAGCLARAKDW--RYFQRDG-KWFARETNTMPQWAGS 571 
255554793  521 ----------------TGEGVPLLETDLPLRLPELDDFTPTGTGEPPLTKAVSWVKTTDPSSG-KPAKRETNTMPQWAGS 583 
297809613  533 ----------------SGETIAVSESELPLTLPELNDFTPTGTGEPPLSKAVSWVNTVDPSTG-KPAKRETSTMPQWAGS 595 
302834659  510 ----------------SDEAVPLPESSLPLTLPDTDRFKPSGTPESPLAAIPSWVNTVDPRDGvTPARRETSTMPQWAGS 573 
303280587  638 ----------------SDVPVAVPESELPLTLPDTDNFKPSGSGEGPLANIEDWVATVDPLGG-GPARRETNTMPQWAGS 700