302773171 5 IDPSREFTRDVRRVIVKVGTSVVTRPDGKLAVGRLGALCEQVKDIMDDHIEVIVVTSGAVAVGRQKLRQQRMMNSrqvrr 84 168007186 1 MDRSRIFIRDAKRVVIKIGTAVVTRHDGRLALGRLGAICEQVKELITDGIEVIFVTSGAVGVGRQKLRHQRMMNSrr--- 77 219111601 11 EPASRAALRRARRVCVKAGTSVVANEDGRPSLTRLGAMTEQIADLVQSGIQVILVSSGSVGMGKRLLRKQRNLQM----- 85 115464247 4 VDPSRSFVRDVKRVIIKVGTAVVSRQDGRLALGRVGALCEQVKELNSLGYEVILVTSGAVGVGRQRLRYRKLVNS----- 78 115441045 23 TDSTRGFVKDVKRIIIKVGTAVVTGPNGRLAMGRLGALCEQVKQLNFEGYEVILVTSGAVGVGRQRLKYRKLVNS----- 97 224002817 6 EPESRRALRNTRRILIKAGTSVVANDDGRPSLTRLGAICEQIAEIHRSGVQVIMVSSGATGMGKRLMRQHGRMNM----- 80 225449372 6 MDPTRAFVKDVKRLVIKFGTAVVTRSDGRLALGRLGALCEQIKELNSQGYQVIVVTSGAVGLGRQRLRYRSLLNS----- 80 225440484 1 MDSSREFVKDVKRVIVKVGTAVVTRADGRLAVGRVGALCEQLKELNSQGYEVILVASGAVGVGIQRLRYRRLVNS----- 75 255566490 5 MDRSRAFVKDVKRLVIKVGTAVVTRGDGRLALGRLGAFCEQVKELNSQGYEVIVVSSGAVGLGRQRLRYRKLVNS----- 79 302799430 5 IDPSREFTRDVRRVIVKVGTSVVTRPDGKLAVGRLGALCEQVKDIMDDHIEVIVVTSGAVAVGRQKLRQQRMMNSrqvrr 84
302773171 85 vihhfcfllVCLDLQKPQAELS--GKACAAIGQAGLMALYDSIFSQLDVASSQLLVTDREFIDPEFRKQLCETVDTLLQL 162 168007186 78 --------vIFVDLQKPQVELD--GKPCAAVGQSGLMALYDSLFSQLDVASSQLLVTDNDFKDPEFRQQLSETVNSLLAL 147 219111601 86 ---------SFRDIHNNDHYYD---SACAAAGQFEMMNLYCGLFASYDITASQILVTQTDFVDESRQRNLQYSIERLLGL 153 115464247 79 ---------SFADLQKPQMELD--GKACAAVGQSGLMALYDMLFNQLDVSSSQLLVTDSDFENPKFREQLTETVESLLDL 147 115441045 98 ---------SFADLQNPQMDMD--GKACAAVGQSVLMAIYDTLFSQLDVTSSQLLVTDRDFMDPSFGNQLRETVNSLLDL 166 224002817 81 ---------SISEMASIGDGLDklEMACAAAGQFEMMNLYNSLFSQMDVSAAQVLLTEGDFRSEDHLNNLHYSIERLLSV 151 225449372 81 ---------SFADLQKPQAELD--GKACAAVGQNNLMALYDTLFSQLDVTSAQLLVTDNDFRDEAFRNQLTQTVDSLLAL 149 225440484 76 ---------SLDDLQKPQIELD--SKACAAVGQSSLMALYDTLFSQLDVTASQLLVTNSDFRNPDFRMQLSETVGSLLDL 144 255566490 80 ---------SFADLQKPQVEID--GKASAAVGQSSLMALYDTMFSQLDVTSAQLLVTDNDFRDKDFRKQLNETVESLLSL 148 302799430 85 vihhfcflfVCLDLQKPQAELS--GKACAAIGQAGLMALYDSIFSQLDVASSQLLVTDREFIDPEFRKQLCETVDTLLQL 162
302773171 163 RVVPIFNENDAMSTRRAPYKDSSGIFWDNDSLAALLALELKVDLLILLSDVEGLYTGPPSDPSSKLISTYIPAQHET-IT 241 168007186 148 RVVPIFNENDAISTRKSPYFDSTGIFWDNDSLAALLALELQADLLILLSDVEGLYTGPPSEPKSQLIHTYLKEKHDDmVT 227 219111601 154 GIVPIINENDAVSANMG--YTADDVFSDNDSLAALCARHFGAEVLLLLTDVPGVFDRPPTEPDATLLRLY---QSQP-VA 227 115464247 148 KVIPIFNENDAISTRKAPYEDSSGIFWDNDSLAGLLALELKADLLILLSDVDGLYSGPPSEPSSKIIHTYIKEKHQQeIT 227 115441045 167 KVIPVFNENDAISTRRQPYEDSSGIFWDNDSLARLLAQELKADLLIMLSDVEGLYSGPPSDPQSKIIHTYVHEQHGKlIS 246 224002817 152 GIIPIINENDAVSANRG--YTQGDLFSDNDSLAALCARSFACDLCILLTDVDGVFDRPPKEKGAKLLPFYSQNQS---VG 226 225449372 150 RVIPIFNENDAVSTRKAPYEDSSGIFWDNDSLAGLLALQLKADLLVLLSDVDGLYSGPPSDPRSKLIHTYLEKGHQGqIT 229 225440484 145 RVIPIFNENDAISTRDHPNEDSSGIFCDNDSLATLLALELKADLLVLLSDVEGLYNAPPNKPHAELIHTYVKEKHEGeIT 224 255566490 149 RVIPIFNENDAVSTRKAPYEDASGIFWDNDSLSALLALELKADLLVLLSDVDGLYSGPPSDPRSKLIHTYIKEIHHGeIT 228 302799430 163 RVVPIFNENDAMSTRRAPYKDSSGIFWDNDSLAALLALELKVDLLILLSDVEGLYTGPPSDPSSKLISTYIPAEHET-IT 241
302773171 242 FGEKSRYGRGGMTTKVTAAREVASAG---IPVVITSGYTPDGFHRVLRGDSIGTLFHK---DAHIWTLTINNDARLMAVA 315 168007186 228 FGEKSRVGRGGMTAKVYAAWQAASAG---IPVVISSGCVADGLQRVMRGDHVGTLFHR---DAHQWVDLKETGARNMAVA 301 219111601 228 IGEKSSQGRGGMASKIDAALSAVQPGstcCACVVAAGNDLNVIRSVLAKTPPTTAAVAdfvSDTHQDASVAEQTRILATA 307 115464247 228 FGDKSRVGRGGMTAKVKAAVLASNSG---TPVVITSGFENRSILKVLHGEKIGTLFHK---NANLWESSKDVSTREMAVA 301 115441045 247 FGEKSRVGRGGMQAKVAAAFTASSKG---IPVVIASGFAIDSIIKVMRGEKIGTLFHR---EANQWGCSKEATAREMAVA 320 224002817 227 IGEKSKHGRGGMDSKINAAQFAVSPGsqtRACVVISGADLNAIRSVTSKEYDPTLSKG---PKGTFAESVSAEAHRMATA 303 225449372 230 FGDKSRVGRGGMTAKVKSAVYSSQAG---IPVVITSGYATGSILKVLNGERIGTLFHR---DAYKWVQVKEVGAREMAVA 303 225440484 225 FGDKSKVGRGGMTAKVKAANQAADAG---TPTVITSGYATDNIIKVLQGQRVGTLFHK---DAHSWTLVKEIGAREMAVA 298 255566490 229 FGDKSRVGRGGMTAKVKAAVNAAYAG---IPVIITSGFARENILKVLQGERVGTLFHQ---DAHIWVPIKEVCGREMAVA 302 302799430 242 FGEKSRYGRGGMTTKVTAAREVASAG---IPVVITSGYTPDGFHRVLRGDSIGTLFHK---DAHIWTLTINNDARLMAVA 315
302773171 316 ARDSSRRLQSLTSGERQNILYDVADALERNEETIRSENQADVRLAEELGIAKPLLSRLTLKPGKIADLAKAVRALADMRE 395 168007186 302 AREGSRRLQGLTSEERKSILHAVADALLANEAIIKAENDADVELAQMTGVSKALVGRLTIKPGKIAALASSLRTLADMKE 381 219111601 308 ARTQARKLQALPYGARQTILNAVADALLTHQEALMEANLLDLQAAERDGVSEVLKKRLGLTLQKFDTLAAGIRQISANKD 387 115464247 302 ARDCSRHLQNLSSEERKKILLDVADALEANEDLIRSENEADVAAAQVAGYEKPLVARLTIKPGKIASLAKSIRTLANMED 381 115441045 321 ARDCSRHLQKLSSEERKKILLDIADALEANEDLITSENQADLDLAQDIGYDKSLVARMTIKPGKIKSLAGSIREIADMED 400 224002817 304 ARDQARKLQGLSHSERKTILYAVADELQAEKVALLAANKLDLEIAERDGTEFPLVSRLKLTEAKLATLSAGIRQIADQPD 383 225449372 304 ARESSRRLQAMSSQDRKKILLDIANALETNEELIKIENDADVEAAQLAGYEKSLVSRLVLKPGKISSLANSIRVLANMEE 383 225440484 299 ARECSRRLQALPSKDRRKILLDIADALEANESLIKVENEVDVAAAQEAGYDKSLLSRLTLKPGKISGLAKSIRMLADMKE 378 255566490 303 ARESSRRLQALSSQERKRILLDIADALEANEEQIKIENEADVAAAQLAGLEKSLISRLALKSGKIKSLANSIRVLANMED 382 302799430 316 ARDSSRRLQSLTSGERQNILYNVADALERNEETIRSENQADVRLAEELGIAKPLLSRLTLKPGKIADLAKAVRALADMRE 395
302773171 396 PIGSILQRTEVAENLTLDKTSCPLGVILVIFESRPDALVQIASLAIKSGNGLLLKGGKEAARSNAILHKVITEALPKSVG 475 168007186 382 PIGEVLKRTEVAEGLTLEKTSCPLGVVLVVFESRPDALVQIASLAIRSGNGLLLKGGKEAARSNAILHKVITEALPKSVG 461 219111601 388 PLGVIHSRRELADNLVLSQVTVPIGVLLIIFESRPDSMPQISALALASGNGLLLKGGKEATHSNAAIHKVIGDAIEESSG 467 115464247 382 PINQILKKTEVADDLVLEKTSCPLGVLLIVFESRPDALVQIASLAIRSGNGLLLKGGKEAIRSNTILHKVITDAIPRNVG 461 115441045 401 PISHTLKRTEVAKDLVFEKTYCPLGVLLIIFESRPDALVQIASLAIRSGNGLLLKGGKEAMRSNTILHKVITGAIPDVVG 480 224002817 384 PLGVVKAKRELADGLVLSQITVPIGVLMIIFESRPDSMPQISALALASGNGLLLKGGKEAAHSNEAIHKVIGNAVEKGSG 463 225449372 384 PIGHVLKRTEVADGLILEKMSCPLGVLLIVFESRPDALVQIASLAIRSGNGLLLKGGKEAKRSNAILHKVITEAIPDSVG 463 225440484 379 PIGHVLSRMELADGLILEKTSCPMGVLLVVFEARPDALVQIASLAIRSGNGLLLKGGKEANRSNAILHKVITEAIPDTVG 458 255566490 383 PIGCVLKRTELADGLLLEKTSSPLGVLLIIFESRPDALVQIASLAIRSGNGLLLKGGKEAKRSNEILHKIITAAIPETIG 462 302799430 396 PIGSILQRTEVAENLTLDKTSCPLGVILVIFESRPDALVQIASLAIKSGNGLLLKGGKEATRSNAILHKVITEALPKSVG 475
302773171 476 KE----LIGLVTSRDEIPDLLKLDDVIDLVIPRGSNKLVSQIKESTKIPVLGHADGICHVYVDKA-ARLDVATKIAIDSK 550 168007186 462 PN----LIGLVTSRDEIPDLLKLDDVIDLVIPRGSNKLVAQIKATTKIPVLGHADGVCHVYVDTA-ADLEKAKNIVIDSK 536 219111601 468 GEitrdIIALVTSRGQVADLLSLDDVIDLVIPRGSNDLVSYIKSHTKIPVLGHADGVCHVYVDES-AAADAASKLCVDAK 546 115464247 462 EK----LIGLVTTRDEIADLLKLDDVIDLVIPRGSNKLVSQIKASTKIPVLGHADGICHVYIDKS-ADMDMAKHIVMDAK 536 115441045 481 KK----LIGLVKNKDEIADLLKLDDVIDLVIPRGSNKLVSQIKAATKIPVLGHADGICHVYIDKS-ADMDMAKRIVLDAK 555 224002817 464 GKitrdIIALVTSRGQVADMLKLDDVVDLVIPRGGNTLVSFIKANTRIPVLGHADGVCHVYVDKSaNDTAAVCKLVVDAK 543 225449372 464 KK----LIGLVTSREEIPNLLKLDDVIDLVIPRGSNKLVSQIKDSTKIPVLGHADGICHVYVDKS-ANMDTAKHIVLDAK 538 225440484 459 EK----LIGLVTTREQIPDLLKLDDVIDLVIPRGSNKLVSQIKDSTKIPVLGHADGICHVYIDKS-ANMKMAKHIVLDAK 533 255566490 463 GK----LIGLVTSRDEIPDLLKLDDVIDLVIPRGSNKLVSQIKASTKIPVLGHADGICHVYVDKS-ANMEMAKRIVLDAK 537 302799430 476 KE----LIGLVTSRDEIPDLLKLDDVIDLVIPRGSNKLVSQIKESTKIPVLGHAD--------KA-ARLDVATKIAIDSK 542
302773171 551 VDYPAACNAMETLLVHEDLVDTGGLETL----ASALKSAGVTLNGGERASKL-LNIPKMTKFHHEYSGLACTVEVVKDVH 625 168007186 537 VDYPAACNALETLLVHEDLVATGGLEML----AFALQSAGVTLYGGARASGI-LKLPRASSYHIEYSALSCTVEVVKDVQ 611 219111601 547 TDYPSACNAMETLLLHAATLSNGVAAAT----LMALRASGVQCLGGPAAMKSgLCDRAAPELKHEYGDLTCLVEVVPNLE 622 115464247 537 IDYPAACNAMETLLVHKDLMKSPGLDDI----LVALKTEGVNIYGGPIAHKA-LGFPKAVSFHHEYSSMACTVEFVDDVQ 611 115441045 556 VDYPAACNAMETLLVHKDLNRTEGLDDL----LVELEKEGVVIYGGPVAHDT-LKLPKVDSFHHEYNSMACTLEFVDDVQ 630 224002817 544 TDYPSACNAMETLLLHRDTLQATAVGNIamsaLMSLRAAGVKCLGGPKAMKTgLCDIPAQEMKCEYGDLTCMVEIVEDMD 623 225449372 539 VDYPAACNAMETLLVHKDLVQTGGLNQL----IVELRNEGVTLYGGPRASAL-LNLPEAHSFHHEYNSMACTVEIVDDVH 613 225440484 534 TDYPAACNAMETLLVHKDFLSNGGFNKL----VTELQRKGVTLHGGPRASAL-LNISQVNSFHHEYNSMACTVEIVDDVH 608 255566490 538 IDYPAACNAMETLLVHKDLVQTGGLNEL----TVDLRTEGVNLYGGPRASKE-LNVPEVDSFHHEYNSMACTIEIVDDVY 612 302799430 543 VDYPAACNAMETLLVHEDLVDTGGLETL----ASALKSAGVTLNGGERASKL-LNIPKMTKFHHEYSGLACTVEVVKDVH 617
302773171 626 AAINHIHEHGSAHTDCIV-TEDKEVAELFLQQLDSAAVFHNASTRFSDGTRFGLGAEVGISTSRIHARGPVGVEGLLTTR 704 168007186 612 EAIDHIHEHGSAHTDCIV-TENHITAETFLHHVDSAAVFHNASTRFSDGARFGLGAEVGISTGRIHARGPVGVEGLLTTR 690 219111601 623 AAIDWIHKYGSGHTEAIVcGEESDVGEEFLRKVDAACVFRNASTRFADGFRFGLGAEVGISTGRIHARGPVGVEGLLTTK 702 115464247 612 SAIDHIHRYGSAHTDCIV-TTDDKVAETFLRRVDSAAVFHNASTRFSDGARFGLGAEVGISTGRIHARGPVGVEGLLTTR 690 115441045 631 SAIDHINRYGSAHTDCII-TTDGKAAETFLQQVDSAAVFHNASTRFCDGARFGLGAEVGISTGRIHARGPVGVDGLLTTR 709 224002817 624 EAIDWIHKYGSGHTESIVcADDSDAGEEFLKRVDAACVFKNASTRFADGYRFGLGAEVGISTGRIHARGPVGVEGLLTVK 703 225449372 614 SAIDHIHRHGSAHTDCII-AEDLEVAEVFLRQVDSAAVFHNASTRFCDGARFGLGAEVGISTSRIHARGPVGVEGLLTTR 692 225440484 609 SAIDHIHRHGSSHTDCII-TEDSKIAEIFLLQVDSAAVFHNASTRFCDGARFGLGAEVGISTSRIHARGPVGVEGLLTSR 687 255566490 613 AAIEHIHEHGSAHTDCII-TEDHEVAEVFLCQVDSAAVFHNASTRFSDGARFGLGAEVGISTSRIHARGPVGVEGLLTTR 691 302799430 618 AAINHIHEHGSAHTDCIV-TEDKEVAELFLQQLDSAAVFHNASTRFSDGTRFGLGAEVGISTSRIHARGPVGVEGLLTTR 696
302773171 705 WLLRGNGQVV-----QGDRGVVYTHKDVEVDS 731 168007186 691 WLLRGSGQLV-----NGDKGVQYTHKKLPIGE 717 219111601 703 WQLR---------------------------- 706 115464247 691 WILRGRGQVV-----NGDKDVVYTHKSLPLQ- 716 115441045 710 CILRGSGQVV-----NGDKGVVYTHRELPLQ- 735 224002817 704 WQLRSTGVNCvqeygGGDPQKVYTHKELI--- 732 225449372 693 WILRGNGQVV-----NGDKG-XYLHPQGAYFA 718 225440484 688 WILKGNGHIV-----DGDEGVIYTHKSLALQS 714 255566490 692 WILRGNGQVV-----DGDKGVIYTHKDVTHIH 718 302799430 697 WLLRGNGQVV-----QGDRGVVYTHKDVEVDS 723