Conserved Protein Domain Family
Tic110

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pfam16940: Tic110 
Chloroplast envelope transporter
Tic110 is a family of chloroplast envelope proteins. Some are involved in protein translocation and others are neurotransmitter receptor, cys loop, ligand-gated ion channel or LIC proteins.
Statistics
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PSSM-Id: 374895
Aligned: 13 rows
Threshold Bit Score: 633.278
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_002957380   72 DSGQQLLSSIPL---MLLYPGFLAAVAAAGYGGSLLGrAAPVDPsakDVAAYGTAAVAAAAV-AYGCVqakrkrdSAA-- 145 
KRH17141       61 KGIELLVDKLSPparLATSAVIVAGAAAAGYGLGSRF-GGSRYA---ALGGAVALGAAGGAA-AYALN-------AAApq 128 
XP_003551181   55 CGIEHLVDKLSPpvrLATSVVVFAAAASAGYGLGSKL-GGCQNV---AIGGAVAFGVAGTAA-AYALN-------AVApq 122 
Q8LPR9         78 TGLQPIVEKMTPpvrLATSAVVLAASLATGYGLGLRL-AGSRNI---AFGGAAVAGAAGGAV-VYALN-------SAVpe 145  thale cress
XP_002319406   68 SGAQSIVSNLSPtlrLASSALILAGALAAGYGLGTKFgGGSRNL---ALGGGAVAGAAVGAV-VFSLN-------SAVpe 136 
XP_010234858   89 TGVQPLVESLPPaarTAAELAVAAAAVAAGYGIGLRLgGGSRAA---AVAGAAVLGAASVAG-AAAVN-------SVVpe 157 
XP_009382116   83 SGPQALVCALPPparMASSAVLAAAAMAAGFGLGLRV-GGSKVA---GIGGAAVLGVAGGAA-VYALN-------SKVpe 150 
XP_002966718   79 SGPKKLLEGMPAptrYVTCTAIVAGALMAGYAVGSQA-KGTPNA---ALAGAIALGAVGGAT-AFVVN-------SMApd 146 
XP_002503178   65 DQLEAQQSALGQa-rLGAYGVVVGGALAVGAAAGTAT-GS-------NAAKAVLTAGLGAGA-AVAVAtadkkrvSAApk 134 
XP_005844387   65 DGLQSALAGLPT-----AGVYVLGAALAAGLGGAGFVgAGAVAPegvRQAARVVAGAAGAALgAFLTAqlkakrqSAA-- 137 
XP_006846995   72 SGVQKLVDSMPSsvrYVSSVVIVAGALASGYGLGMKV-KGTRAA---AIGGAVALGAAGGAV-AYALN-------SCVpd 139 
CBI15848       71 SGIQPLVDSLSPplrLVSSALIVAGAIAAGYGLGFRF-GKSRNT---ALGGAVAIGAAGGAA-AYALN-------ACVpe 138 
XP_004246966   72 SPIQSLVDAMSPpirIASSALIFAAAIAAGYGLGLRF-GGSRNA---GLGGAIAFGAAGAGA-AYALN-------SCApq 139 
XP_002957380  146 --VVDLYNALVDLPDATDLTPETVSDVGSKYGINFQKDELD-GLKRIYGQYLESVIPVGDVQLKGDEAAKVAAFKDILGL 222 
KRH17141      129 vaAVNLHNYVAAFDDPSKLKKEEIEAIASKYGVSKQDEAFKaEICDIYSEFVSSVLPPGGEELKGDEVDRIVSFKNSLGI 208 
XP_003551181  123 vaAVNLHNYVVGLDNPFLLKKEDIDGISNRYGVSKQDDAFKaEICDIYSHFVSSLLPPGDVELKGDEADKIISFKNSLGI 202 
Q8LPR9        146 vaAISLHNYVAEFEDPASVTKDDVEKIADRYGVNKGDEAFQaEICDIYCRYVTSVLPTEGQSLKGDEVAKIVKFKNALGI 225  thale cress
XP_002319406  137 iaAINLHNYVSGFDDPTKVSKEEIEGIAKKYGVSKQDEAFNaELCDLYCQFVSSVLPPGGEELRGNEVDTIINFKNALGM 216 
XP_010234858  158 vaAVGLHNYVVGCDDPTKLETSEVEAIASKYGVSTQDAAFKaELCDLYASFLYSVLPPGDEDLKGNEVEVITKFKSALGL 237 
XP_009382116  151 vaAISLHNLVAGYDDPTELRKDEVAAIVEKYGVSKQDDAFKaELCDLYSRFVSSVLPPGSENLKGYEVEMIIRFKEALGI 230 
XP_002966718  147 vaAAQVHNLLVNHPDPRSLRGEEIEGILKKFGINKTNEKFNtELRNLYDSFVSSVIPPGNEDLKGDEAATIRKFKEALGL 226 
XP_002503178  135 alWNGMLN-----RDPATITKADVDAIGAKFGMKDMSKDCPeAVTELYDAYLQSIVPMGDDPVQGWEPEALRNFRQQLGL 209 
XP_005844387  138 --IIELSNLLVEMGDPTALTREQVAAIEAKYGASLAATNPD-ELKSIYGAFLEAVVPPGDAPLTGSEPVLIQAFKAALAL 214 
XP_006846995  140 vaAANLHNMVVRSGDPRSLEKEAVDEIANRYGVSRQNEAFNaELCDLYSRFVSSVLPPGGENLRGDEVDSIIQFKNSLGI 219 
CBI15848      139 vaAANLHNYVAGCDDPGAVKKEDIEEIANKYGVSKQDEAFNaELCDLYCRFVTSVVPPGSEDLKGDEVDTIIKFKSSLGI 218 
XP_004246966  140 vaAINLHNYVADFDNPAALNKEDIESIANKYGVSKQNEAFNaELRDIYCRYISAVLPASTEELRGDEVDTIIKFKNALGI 219 
XP_002957380  223 ADEDAAPVHIEVGRRFMREGFETKDRNAVFEKRKAFQRLIYVSQVVFGDqKAAFLLPWRRTFNLNDAQ-------IFVAR 295 
KRH17141      209 DDPDAASMHMEIGRKIFRQRLEVGDRDADVEQRRAFQKLIYVSNLVFGD-ASSFLLPWKRVFKVTDSQ-------IEVAV 280 
XP_003551181  203 DDPDAAAMHIEVGRNIFRQRLEVGDCEADIEQYRAFQKLIYMSYLVFGE-ASSFLLPWKHVFKVTDSQ-------VEEAI 274 
Q8LPR9        226 DEPDAAAMHMEIGRRIFRQRLETGEREGDAEQRRAFMRLVYVSALVFGD-ASSFLLPWKRVLKVTDAQ-------VEIAI 297  thale cress
XP_002319406  217 DDPDAASMHVELGRRIFRQRLETGDPDGDVEQRRAFQKLIYVSTLVFGE-ASSFLLPWKRVFKVTDSQ-------VEIAI 288 
XP_010234858  238 DDVDAANMHMEIGRRLYRERLETRDRDADMEQRRAFQKLIYVSNLVFGD-ASAFLLPWKRLFGITDSQ-------IDIAM 309 
XP_009382116  231 DDPDAASVHVEIGRHIYRQRLETGDREADIEQRRAFQKLIYVSTLVFGE-ASKFLLPWKRLFNVTDSQ-------IEIAI 302 
XP_002966718  227 DDPDAAAVHIEICRRIVRQRLETGDRDTAVEELRAFQKLVYVSNLVFGE-ASKFLLPWKRVFKVTDSQ-------VEIAV 298 
XP_002503178  210 EDADAANAHIEVGRRLFRKRIELGDKDADLESRREFQKLVFISTRTFGEkQAKFLLPWNRIFRVSDAQ-------VTLAM 282 
XP_005844387  215 SDVDAAPAHIEVGRRILRGRMEAGSRADDVEARKTFQKLIYVSNLVFGDrQAAFLLPWTRVFGLTEAQasarlscVYVAK 294 
XP_006846995  220 EDPDAASVHMEIGRHIFRQRLETGDRDADIEQRRAFQKLVYVSTLVFGE-ASTFLLPWKRVFKITDAQ-------VEVAI 291 
CBI15848      219 DDPDAAAMHMEIGRRIFRQRLETGDRDGDIEQRRAFQKLVYVSTLVFGE-ASKFLLPWKRVFRVTDSQ-------VEVAV 290 
XP_004246966  220 DDPDAADMHMEIGRRIFRQRLETGDRDGDMEQRRAFQKLIYVSTLVFGE-SSAFLLPWKRVFKVTDAQ-------VDVAV 291 
XP_002957380  296 RDNARAIFRQYLEARGg------mLPADRHVLRELREKQTAIKLMDETAAEVVRDAARRTIESHLTRAIEVAKSTGKelt 369 
KRH17141      281 RDNAQRLFASKLKSVG--------RDIDAEQLVALRKEQQLCRLSDELAENLFRTHTRKLVEENISVAIGILKSRTK--- 349 
XP_003551181  275 RDNAQRLYASKLKSVG--------RDIDAEQLVTLREAQHLYCLSDQLAENLFKEHTRKLVEGSISVAHGILKSHTR--- 343 
Q8LPR9        298 RENAKQLYAERLKLVG--------RDINVENLVDLRKSQLSFKLSDELAEDLFREHTRKVVVENISSALSILKSRTR--- 366  thale cress
XP_002319406  289 RDNAQRLYTSKLKSVG--------KDIDVEQLVNLRQAQISYQLSDKLAEDLFRQHTRKLIEENISAALDRLKSRTR--- 357 
XP_010234858  310 RDNAKNLYTSQLKSIG--------RDLDIGTLIEVRRAQLAYKLSDEIAADMFREHAKKLIQENISSALDILKSRTK--- 378 
XP_009382116  303 RDNAQKLYASKLKLIG--------RDIEVKQLIELRESQLLYRLSDQIAGEMFREHTRELVEENISSALSILKSRGK--- 371 
XP_002966718  299 RDNAQRLFATKLSSIGtgkyssyrTYVNIDQLKELRRIQLKVQLSDEITSSLFKSHTQKLLEGYISRALEVLKARTR--- 375 
XP_002503178  283 KESASNLFKNHVNESGa------iNTLEAGALAAARAYQQELNLKDADCAEVVQKLAQDYVVSKVEAASELAQVRSV--- 353 
XP_005844387  295 RDNAKGIFKQYLDSHGg------qLQADKAFLVGLRQAQAAARLADDEAAALVKEAARARVEELLESAVKSTKQRTR--- 365 
XP_006846995  292 RDNAQRLYALKLNSVG--------RDVDAMQLIDLREAQLQYRLSDEVAADMFREHARKLVEENITIALDVLKSRSR--- 360 
CBI15848      291 RDNAQRLYAFKLKSVG--------RDVDVNQLVSLREAQLSCLLSDELAEDMFKEHTRKLVEENISTALSILKSRTR--- 359 
XP_004246966  292 RDNAQRLYASKLKSVG--------RDIDVNQLISLREAQLAYRLSDELAHEMLKEHARKLVEEIISTAVGILKSRTR--- 360 
XP_002957380  370 cagKARDITLLVEEVDAVLEYDRKLVKYGSEDD---LVAGLGMVTLHGGALD-GEGRTRDLKDVFRLYLEEKlNRAGEFS 445 
KRH17141      350 ---AVPGVSQAVAELDRVLAFNNLLISFKTHPDvdrFARGVGPVSLVGGEYD-GDRKIEDLKLLYRAYVSDA-LSGGRME 424 
XP_003551181  344 ---SVYGVIEAVEELDSVLAFNNILISLKNHPDvdhFAQGVGPVSLLGGEYD-GDRKIEDLKLLYRAYIANA-LSSGRME 418 
Q8LPR9        367 ---AAKSLASVVEELEKVLEFNNLLVSLKSHSEadqFARGVGPISLIGDESD-FERRMDDLKLLYRAYVTDA-LSGGRLE 441  thale cress
XP_002319406  358 ---TVQDVVKVVEELDKILAFNNKLISLKNHTDaasFACGVGPVSVLGGEYS-SERKIDDLKLLYRAYITDA-LYGGRME 432 
XP_010234858  379 ---AANSPTQVIEEVKIVLAFNSLLTVLSKHPQgdrFVRGLGPISLAG-ELD-HDRRAGDLKILYRAYATEV-LSDGPLD 452 
XP_009382116  372 ---TSMGTLQVIEELEKVLAFNNLLTSLSKHSDsgqFAQGVGPVSLIGGEFD-GDRKIEDLKLLYRTYAEES-FSSGCLQ 446 
XP_002966718  376 ----IKDTKKLVMELESMLAYNDLLSALAKDADsssLVPGVGPASVIGGVYD-SDRAMDDLKLLYRTYLSEAvVSNGQLL 450 
XP_002503178  354 ----NSDFTEANKLLTEVLDYNKKMGAGGD------ALPGLQVVTLAGSSFE---DKSGEANTLFRNFVTQG-TEAGEFS 419 
XP_005844387  366 ----TRDYTEAMAALTAAVAFNRGLAALSSDPE---VIAGVGPTSVLGGAWEaADGRSKDTRELFKIFLEERlLSDGAFT 438 
XP_006846995  361 ----TKGLTKVVEELEKIIAFNKLLVSLSNHPEvarFAQGIGPVSLLGGEYD-SDRKIDDLKLLYRAFVTES-YSSGRME 434 
CBI15848      360 ---AVRGATQVVEELNKALAFNNLLISLKNHPDagrFACGVGPISLMGGEYD-GDRKMDDLKLLYRAYVADS-LSSGRMV 434 
XP_004246966  361 ----ATEPTRVIEELDKVLSYNNLLISLKNHADasrFAPGIGPVSLVGGEYD-GDRKMDDLKLLYRAYVTDS-LSSGRME 434 
XP_002957380  446 AQMDADAAELATIMCMGAKETQALRDEVSAKLYRRLLKEEVTSGRLDSATSPASVLQSLCDKVRFRPEAALELHRQLYKA 525 
KRH17141      425 DDKLAALNQLRNIFGLGKREAEAISLDVTSKVYRKRLAQAVADGELEMADSKAAFLQNLCDELHFDPQKASELHEEIYRQ 504 
XP_003551181  419 DNKVAALNLLRKFFGLGKREAEAIMLDVTSRVYRKKLAQAVSGGSLEMTDSKETFLQKLCDELHFDPQKACEIHEEIYRQ 498 
Q8LPR9        442 ENKLVAMSQLRNILGLGKREAEAISVDVTSKSYRKRLANAVSSGDLEAQDSKAKYLQKLCEELHFDAQKAGAIHEEIYRQ 521  thale cress
XP_002319406  433 EHKLAALNQLKNIFGLGKREGESIRLDVTSKAYRKRLAQAVSSGDLEYADSKAAFLQNLCEELHFDPLKATEIHEEIYRE 512 
XP_010234858  453 NEKLIPLNELRNIFGLGKREAEAIISDVKSQVYRKRLAKCFNT-ELAAAPSKASFLQNLCEELEFDPELASKMHEDIYRQ 531 
XP_009382116  447 EEKLTALSQLRNIFGLGKREAENIMLDVTSRVYRRRLSRAFSGGDLDAAPSKAAFLQNLCEELHFDPNIASKIHEEIYRQ 526 
XP_002966718  451 KEKLPLLAQLKNTFGIGNREADDIMLDITTKVYRRRLSLAVTDGDLDAATSKATFLQNLCNSLQFDPAKASKVHEEIYRQ 530 
XP_002503178  420 AELKSSAGALKVLFGMGNKEAEEIVLDVTTKRYRELLRDAVKSGELDKAESPAKVLQSICEKLQFPPEVAADVNKENYRT 499 
XP_005844387  439 DGLEADAAQLRTLMGLGNKECADIEADVKQAAYKRLLREEVTTGRLAAAESKAEVLGDLVERVRFDADAARAFHEALYRQ 518 
XP_006846995  435 DKKLEDLNQLKIIFGLGKREAETMLLEVASKVYRKRLAQAVSSGDLDIATSKAAYLQNLCEELHFDPQKASEIHEDIYKQ 514 
CBI15848      435 ENKLAALNQLKNIFGLGKRETEGIMLDVTSKAYRKRLAQSVSGGDLEAADSKAAFLQNICDELHFDPKKASEIHEEIYRQ 514 
XP_004246966  435 EDKLAALNQLRNIFGLGKREADTITLDVTSKVYRKRLAQAVTSGELEAFESKAAYLQNLCEELIFDPQKALEIHQEIYRQ 514 
XP_002957380  526 KLSALLEARRghggLTDGDVEDLKRIRRILCLPADVAKKVMRETAGREFEELVGEIYLAGAKPLGSYEAERVDRALKELR 605 
KRH17141      505 KLQKCVADGE----LNEEDVAALLRLRVMLCIPQQIVETAHSDICGSLFEKVVKEAIASGVDGYDAEIQKSVRKAAHGLR 580 
XP_003551181  499 KLQQLVADGE----LSDKDAAALLRLGVMLCIPQQTIDTAHSDICGSLFEKVVKDAIASGVDGNGAEMRKSVRKAAHGLR 574 
Q8LPR9        522 KLQQCVTDGE----LSDDNVAALLRLRVMLCIPQQTVDTAHAEICGTIFEKVVRDAISSGVDGYDAETRKSVRKAAHGLR 597  thale cress
XP_002319406  513 KLQQCAADGE----LSDEDVKALTRLRVMLCISQQIIDAAHSDICGSLFEKVVKDAIASGVDGYDADVKKAVRKAAHGLR 588 
XP_010234858  532 KLQQFVADGE----LSKDETEALMAFQVRLCIPQETVDAAHTDICGQLFEKVVKEAIVS-VDGYNADRRDAVRKAAQGLN 606 
XP_009382116  527 KLRQFVEDGE----LSEEEVASLQRYRVLLCIHHETIDAAHADICGRLFEKVVKDAIASGVEGYDAEVRNSVRKASKGLR 602 
XP_002966718  531 KLEQCVADGS----LSDEDISALLRLRVLLCIPQETVETAHADICGRIFAKVVNTAIASGVDGYDPETTATVRAAIKGLR 606 
XP_002503178  500 KMEQVMEKKK----LTDEDVEALGRVRRLLCVPKDVVDECTMDICGAVYKSAVLSALSVGTESFTPELRDRCKRAKDAVR 575 
XP_005844387  519 KLASLLEKKK----LTEEDDVALREMQVQLCIQNEERDRMHAELCGALFKDAVTDALAAGIDGFGFQDRQRVQQAFKDLR 594 
XP_006846995  515 KLQQAVADGD----LSDDDVASLLRLRVMLCIPQQTVDAAHADICGRLFEKAVRDAIAAGVEGYDADVRRTVRKASQGLR 590 
CBI15848      515 KLQQCVADGE----LNEEDVAILLRLRVMLCVPQQTVEAAHADICGSLFEKVVKDAIASGIDGYDDDVKKSVRKAAHGLR 590 
XP_004246966  515 KLQLLVTDGE----LSDEDMKALERLQVMLCVPKQTVEAAHADICGSLFEKVVKEAIACGIDGYDTETKNAVRKAAYGLR 590 
XP_002957380  606 LDSDVAVEVMAQITRERFRSYVTQAQreGSRDRRDFAASVKKLLQFNALMVTPLL 660 
KRH17141      581 LTREVAISIASKAVRKIFINYIKRAR--AAGNRTESAKELKKMIAFNTLVVTNLV 633 
XP_003551181  575 LTGDTAMSIASKTVRKIFINYIKRAR--AAGNCTESAKELKKMIAFNTLVVTELV 627 
Q8LPR9        598 LSRETAMSIASKAVRRVFTNYIRRAR--AAENRTDSAKELKKMIAFNTLVVTEMV 650  thale cress
XP_002319406  589 LTREAAMPIAGKAVRRIFLNYIKRAR--MAENRTEGAKELRKLIAFNSLVVTELV 641 
XP_010234858  607 LKKEAAMTIFSKAVRKLFLNYIQRAK--AAGNRIEQAKELKKLISFNTVVVSELL 659 
XP_009382116  603 LTTDAAMAIANKAVRRVFMTYIQRSK--GAGNRTEAARELKKMIAFNALVVTELI 655 
XP_002966718  607 LSQKAAMDIASKAVRTMFMTYVKRSR--TADNRTESARELKKMILFNNLVVTELV 659 
XP_002503178  576 LTDDMALKILKNEVVKAFMAYIRVAR--TKQNKIEQSKEIRKMVYFNSTVVTPMV 628 
XP_005844387  595 LERPAA----------------RASR--NTRNRLDAAKELKKLVFFSNIVVAPLV 631 
XP_006846995  591 LTTDTAMAIASKAVRAMFTNYIKRSR--AAGNRTEAAKELKKMIAFNTLVVTQLV 643 
CBI15848      591 LTREAAMSIASTAVRKIFMNYVKRSR--AAGNRIEAAKELKKMIAFNSLVVTELV 643 
XP_004246966  591 LTRDVAMTIASKAVRKIFITYIQRVR--GAGSRTESAKELKKMIAFNSFVASQLV 643 
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