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CS6 fimbrial subunits A and B, Coli surface antigen 6 CssAB is a family of CS6 pilins from E.coli, including both subunits A and B. It acts as a colonization factor for the enterotoxigenic species pf E.coli to mediate bacterial attachment to the small intestinal epithelium. Both subunits in the fibre bind to receptors on epithelial cells, and that CssB, but not CssA, specifically recognizes the extracellular matrix protein fibronectin.
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Jiyao W et al.(2023). "The conserved domain database in 2023.",