Conserved Protein Domain Family
cNMPbd_u2

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pfam16643: cNMPbd_u2 
Unstructured region on cNMP-binding protein
cNMPbd_u2 is a natively unstructured region on a set of higher eukaryote cyclic nucleotide-binding domain-containing proteins. It lies between the second cNMP_binding, pfam00027, and the F-box, pfam00646, domains. The function is not known but there is a highly conserved DPDPFL sequence motif.
Statistics
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PSSM-Id: 406936
Aligned: 26 rows
Threshold Bit Score: 138.36
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_003834713  505 VRRQVESVARERLQ----------SARDKDVEMAD-A---------SST-P--NIDDLAIADsttkt----------att 551 
EGX48498      354 MKREVEATARRRLS----------TADSADTDKME-VdplsvgnsgHST-PtySISRMDLADasaklathlkdpshadsp 421 
XP_014173719  412 lKLQVEETARERYRqsrvaaageaTSDDADVEMSDrRegg---eqmSAIgSnsNREEV---------------------- 466 
CCE29031      403 LKSQVEETARLRWK----------PQDEEDTNMTD-Ldat-------kqsDtsPNSELs--------------------- 443 
EGR48378      392 IKSQVEQTAWHRYN-----------YRDEDVDMAD-Vdprr-kaskSDP-PtpKLARL---------------------- 435 
EHK19130      392 IKLQVEQTAWHRYN-----------NRDEDVDMLD-Adqqg-ktskSDP-PtpRLARL---------------------- 435 
XP_013938113  392 IKLQVEQTAWHRYN-----------YRDEDVDMTD-Agqqe-ktskSDP-PtpILARL---------------------- 435 
ELR07898      389 IRKQVEATAKARYG----------RPKDEDVLMTG-Vd--------STT-P--SIKGLKIADr----------------- 429 
EPE24581      391 IRRQVEVTAKERIP----------RPESEDTLMTD-----------GDG-DesPISRLEIDv------------------ 430 
EKD18143      390 IRRQVEQTAKTRIG----------KSEDQDVHMVD-----------IDD-P--STNSLENHE------------------ 427 
XP_003834713  552 tPRTPRRKRSVPSVTFNEPttAMDSPM---TPTRREDKMMEP--YDPDPFLNVDLDNVRSRS-RRGSLAPPTPGSm---- 621 
EGX48498      422 lKQSLAPHSEQPETTFPG------------------INVIEP--LDPDPFLPADFDSMRAKS-RRGSLAPPPPAP----- 475 
XP_014173719  467 ---LSLRRPSVPHVTFTTPs-KPSSPT------TDEADMRQP--SDPDPFLSVDMENLRNR--RRNSLAPPLPAG----- 527 
CCE29031      444 -APSTPSKGLLANLAFASPg-SQGSPN------KDDFELMEP--KDPDPFLSVNMENLRNR--RRHSLAPPLPLTaegvv 511 
EGR48378      436 ---------SIPDVGFTTPf-KPLSAS-----PRDASEVMEP--KDPDPFLSVDMENLRNR--RRHSVAPPTAPT----- 491 
EHK19130      436 ---------SLPDDNFATPl-KPIAGT-----PRDDSDVMEP--KDPDPFLSVDMENLRNR--RRHSIAPPTTPT----- 491 
XP_013938113  436 ---------SLPDVEFGAPl-KRISTK-----ARDDSDTMEP--KDPDPFLSVDMENLKNR--RRLSIAPPSAQT----- 491 
ELR07898      430 -SPKSKVR-DLPRVTFTPS--KPLSPPhqtNLLEEKDN-VEStdTDPDPFLSIDMDNMRSRMsRRSSWAPIPPEFi---- 500 
EPE24581      431 -SLRTPRRGSLPQVTFTPS--KPASPHk-pSRVEDKD-IMEP--LDPDPFLSVDMDKMRTRNaRRGSLAPPTPET----- 498 
EKD18143      428 -RPITPNRCTLPEVTFTPS--KFASSHt-pSRAEDQDN-MEP--TDPDPFLSVDMDNMRSRTpRRGSLAPPVPET----- 495 
XP_003834713  622 -HALDPPPPPPSPtksDFGKPASTSVSPLAPSPl-LLPKHASTPP-EAPFd-----------yKRPRMIHLP 679 
EGX48498      476 --------TVPTS-------GEADIERPISPSP--NKSKHPTTPP-EHYSs-----------aKRARIVQRR 518 
XP_014173719  528 -------DSSSGG------QTTPSPQIENNSSPlkLFTFPPLTAAeEPTAaepeeerssrgrfKKARTLAHR 586 
CCE29031      512 tGRTNGYRASLVDligPTIRSGSSDTSSECGVPs-----------------------------KRARTATSR 554 
EGR48378      492 -TPTTPTETAPTT---PAKQNGTRTHLPEQPSPm------sVTAPePELFdm---------paKRAKTLSHR 544 
EHK19130      492 -------EASSTT---PTRHNGARSPLAEPSSPi------aWTAP-DFESdv---------paKRAKTVSNR 537 
XP_013938113  492 -------EASPTT---PTRQNGARPFVPEPSSPv------aFTMP-DFEFdm---------paKRAKTLSHR 537 
ELR07898      501 sSENESEEAEPQ------------ITRLPGSSP--LSFTHPITPPqESQLr-----------sKRPRTVHRR 547 
EPE24581      499 ----------PPSeekATPPGPRTRSRTQTPTPa-RPAPHSMTPP-DSNr------------pKRPKTVQRR 546 
EKD18143      496 ----------PPPde---qTGPRTRSRSQTPTP--SRPIHAMTPP-DSTFr-----------pKRAKIFQRR 540 
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