Conserved Protein Domain Family
Astro_capsid_p2

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pfam16580: Astro_capsid_p2 
C-terminal tail of astrovirus capsid projection or spike
Astro_capsid_p2 is a family of turkey astroviral spike projections. These are globular domains on the surface of the viral capsid. Astroviruses cause diarrhoea in a variety of mammals and birds, and are small, non-enveloped, single-stranded RNA viruses. The spike carries three conserved patches on its surface which could be candidates for avian receptor-binding sites.
Statistics
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Structure
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PubMed ReferencesClick to see Conserved Features Help

pfam16580 is the only member of the superfamily cl24966
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q1L583     7 AEDQYTPWFVYNFQGQRVSTSESGIFCLSAIPSADSKSRYNNQINSPTVGYRNEGGAGSSFALDNASWWSILDVTQTGVI 86  Turkey astrovirus 2
Q5UAH3   431 ADDQFTPYFVYDFQGKRVSTTETGVFCLFSIPAADSKSRYNSPMTNVSIGYRSDSGTGVSFALDNASWWNILDVTQTGVI 510 Turkey astrovirus 3
Q1L589     7 AEDQYTPHFVYDFQGTRVSTTESGVFCLSSIPSADSKSRYNNQINSPSIGYKNEGGTGTSFAMDSAPWWSILDVTQTGVI 86  Turkey astrovirus 2
ACT79901   6 ADDQYTPYFVYNFQGDRVSTTETGVFCLAAIPAATTTSRYNNQITTPSIGYRNASGTGTSFLLDAASWWNILDVTQTGVL 85 
Q1L586     7 ADDQYTPHFVYDFQGARVSTAESGVFCLAAIPAATTSSRYNGQITSPSIGYKNASGTGTSFSLETASWWNILDVTQTGVL 86  Turkey astrovirus 2
Q1L591     7 ADDQYTPYLVYDFQAGRVSTAETGVFCLATIPIAATSSRYNGLISTPSIGYKSDSGSGTSFQLDEASWWNILDVTQTGVL 86  Turkey astrovirus 2
ACT78377   2 ADDQYTPFFVYNFQGERVSTAETGTFCLAAIPNATASSRYNGQISTPSIGYKSDSGAGVSFQLDAADWWNILDVTQTGVL 81 
ACO50790   3 AEDQYTPYLVYDFQGRRVSTAETGTFCLAGIPIAATSSRYNGLISSPSIGYKGDSG-GVSFRLDEASWWNILDVTQTGVL 81 
Q1L585     7 ADDQYTPHLVYDFQGNRVSTAETGVFCLASIPAATTSSRYNGQITSPTIGYKNASGTGTSFSLDEASWWNILDVTQTGVL 86  Turkey astrovirus 2
Q1L583    87 FGQPRLGVGVIQTMKTPKQHITDFTEPAVKKYYPGTTNLDQT--LKDRMKLTEGDPVISMGDVTGRRAALFYRTSDDRFI 164 Turkey astrovirus 2
Q5UAH3   511 FGQAKYGVGVIQTMKTLKQHIKDFTEPAVKKYYPNTTNIDQE--LKNRLNLAEGDPVISIGDTTGRRAALFYRSSNERFV 588 Turkey astrovirus 3
Q1L589    87 FGQPRLGVGVIQTMKTLKQHITDFTEPAVKKYYPGTTNLDQT--LKDRMKLTEGDPVISMGDVTGRRAALFYRTSDERFI 164 Turkey astrovirus 2
ACT79901  86 FGQPRLGVGVMQTMKTLKQHIKDYTEPAIQKYYPGTTNLDEQ--LKQRLNLAEGDPVISMGDTTGRRAALFYRTSDEKYI 163
Q1L586    87 FGQPKLGVGVTQTMKTLKQHIKDYAEPAIQKYYPGTTNIDDR--LKQRMNLAEGDPVISMGDTNGRRAALFFRTSDEKYI 164 Turkey astrovirus 2
Q1L591    87 FGQPKLGVGVIQTMKTLKQHIKDYTEPAIKRYYPNTTNLDNRdvLKQRMNLAEGDPVISMGDTNGRRAALFYRTSDERYI 166 Turkey astrovirus 2
ACT78377  82 FGQPKLGVGVIQTMKTLKQHIKDYTEPAIKRYYPGTTNLDNGdvLKQRMKLTEGDPVISMGDTNGRRAALFYRTSDERYL 161
ACO50790  82 FGQPKLGVGVIQTMKTLKQHIKDYTEPAIKRYYPGTTNLDNSnvLKQRLDLAEGDPVISMGDTSGRRAALFYRTRDERYI 161
Q1L585    87 FGQPKLGIGVMQTMKTLKQHIRDYTEPAIKKYYPGTTNIAEE--LKQRMKLAEGDPVISMGDTTGRRAALFYRTSDERYI 164 Turkey astrovirus 2
Q1L583   165 MLISTTGDPGSQFESLKTSTFWNWSLSDNKTEFLNRLRTIQYANAGtgglQQEEHHGDSDDDGLSDVTSLFEQADLEDET 244 Turkey astrovirus 2
Q5UAH3   589 LLFSTADDPGPSYASLKMLAFWNWSLSDDKNAFLANLRTVQFAGLC----ESEVPQCDSDDDDLSDVTSLFEQADLGDET 664 Turkey astrovirus 3
Q1L589   165 MLISTTDDPGSQFESLKVTTFWNWSLSDNKSAFLARLRTIQYANAGtgelQQEXSHCDSDDDGXSDVTSLFEQADLEDET 244 Turkey astrovirus 2
ACT79901 164 LFFSTTEDPGAQYQNLKMLYFWNWSYSDTKQQFLDHLRTVQFANLD----DSQPAPYDSDDDDLSDVTSLFEQADLGDET 239
Q1L586   165 LFFSTTEDPGAEYQNLKMLYFWNWSYSDNKQQFLDHLRTVQFANLD----DSQPALCDSDDDGLSDVTSLFEQADLEDET 240 Turkey astrovirus 2
Q1L591   167 LFFSTPEDPGQEYQSLKVLYFWNWSYSDNKQQFLEHLRTVQFANRD----DSQLTPCDSDDDDLSDVTSLFEQADLGDET 242 Turkey astrovirus 2
ACT78377 162 LFFSTPSDPGAEYQNLKMLYFWNWSYSDNKQQFLSHLRTVQFANRD----DSQPALCDSDDDGLSDVTSLFEQADLEDET 237
ACO50790 162 LFFSTPSDPGPEYQHLKMLYFWNWSYSDSQQDFLGHLRTVQFANRD----DSQPAHCDSDDDGLSDVTSLFEQADLEDET 237
Q1L585   165 LFFSTTGDPGAQFENLKMLYFWNWSYSDTKQQFLDHLRTVQFANAD----DSQPVPCDSDDDDLSDVTSLFEQADLGDET 240 Turkey astrovirus 2
Q1L583   245 DFKFKMSIQTS 255 Turkey astrovirus 2
Q5UAH3   665 DFKFNMSIQTS 675 Turkey astrovirus 3
Q1L589   245 DFKFKMSIQTS 255 Turkey astrovirus 2
ACT79901 240 DFKFNMSIQTS 250
Q1L586   241 DFKFKMSIQTS 251 Turkey astrovirus 2
Q1L591   243 DFKFNMSIQTS 253 Turkey astrovirus 2
ACT78377 238 DFKFKMSIQTS 248
ACO50790 238 DFKFKMSIQTS 248
Q1L585   241 DFKFNMSIQTS 251 Turkey astrovirus 2
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