4I8O,5HY3


Conserved Protein Domain Family
RnlA_toxin
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pfam15935: RnlA_toxin 
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RNase LS, bacterial toxin
RnlA_toxin is an RNase LS and a putative toxin of a bacterial toxin-antitoxin pair. Toxin-antitoxin systems consist of a stable toxin and an unstable antitoxin. In this case, a novel type II system, RnlA is the stable toxin that causes inhibition of cell growth and rapidly degrades T4 late mRNAs to prevent their expression, and this is neutralized by the activity of the unstable antitoxin RnlB.
Links
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Statistics
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PSSM-Id: 406376
Aligned: 7 rows
Threshold Bit Score: 96.6672
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
4I8O_A          99 EQVNXVLQGFVETSVLPVLELSAD---ESHIEFR----EHSRNAHTVVwkIISTSYQDELTVSLHiTTGKLQIQGRPLSC 171 Escherichia c...
Q6LR54          93 NKANLVLKGMSSDEIEFVLALMGDelvEGEKAFSittaNPTPICQKYT--ITCDKFKDNIVLLYHtTTYKLQIQGRALFC 170 Photobacteriu...
WP_012498387   220 DDGSILFTSFQKQDWLDIIQKLKE---KNELNILieegIVDENKKSYLnrLIFRLDKDKVTINCY-SNNKSYVQGKQSML 295 Mycoplasma ar...
5HY3_A          90 KNFEYTIPKFSDDDRANLFEFLSE---EGITITEd--nNNDPNCKHQY--IMTTSNGDRVRAKIY-KRGSIQFQGKYLQI 161 Escherichia c...
jgi:Bache_0171  92 DKKSFTAKGISEEDFDAFIDVLSE---SDEIEITtvntDNNPAIRNQY--HLKGKYDAKVSIIFY-NNGTLFLQGAVTAF 165
EIM62925        91 HNNCITYRKIKQDDFELLLEYLDT---EEAVKSEslepYKTNNNHTIF--KISSIYKDETTLTQY-ANQTILLQGRPLYI 164
CDF00583       179 ENASCTFENISDDVFDKLLSYFNE---DDRISVVsdeeKDTSPKHRAI--QCKSKFGDKLFIRHY-ENKSVLIQGNPAYI 252

4I8O_A         172 YRVFTFNLAALLD 184 Escherichia coli K-12
Q6LR54         171 YRTLCYHLSALLD 183 Photobacterium profundum
WP_012498387   296 FQIIITAAIEMLP 308 Mycoplasma arthritidis
5HY3_A         162 ASLINDFMCSILN 174 Escherichia coli O157:H7
jgi:Bache_0171 166 Y---IELITEIME 175
EIM62925       165 YNVIKSFINELID 177
CDF00583       253 FSQLMYFMS-IQD 264
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