Conserved Protein Domain Family
PP2C_2

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pfam13672: PP2C_2 
Protein phosphatase 2C
Protein phosphatase 2C is a Mn++ or Mg++ dependent protein serine/threonine phosphatase.
Statistics
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PSSM-Id: 404547
Aligned: 38 rows
Threshold Bit Score: 103.171
Created: 25-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q82LD0              393 RGDSARYRGEPRRDSLLtarFGVGDQALLLv-AMATGARA------TPGAHRA----AAEACH-WI----GRAVGRSH-- 454 Streptom...
jgi:Franean1_7181    49 TAERHRPRRNDNESFT----VWTDRDGSVCllAVAGAVGD------GENAGRA----ARMATA-LAvqasRRRLASTA-- 111
Q0RFF7              190 VGTAHLVSGAPCQDAYD---FAVSPGGRLIv-AIADGLGS------RPHSQVG----ARSFCEgAV----QAGLA----- 246 Frankia ...
Q7NCD8               64 RGASHYTSGLPNQDAIT----WRTGERPIL--AVADGHGSi----rHFRSQKG----SRLAVE-AM----ASTLESFPat 124 Gloeobac...
jgi:Cyan7425_0409    16 IGAMHQRTGQPNQDALA---WRSDSSLPLIl-AVADGHGSaksfrsHRGSELA----VQIAVE-EM----GKFLSLHS-- 80 
LANL:BG07_5066       19 YGGNTSAGAKKNEDGAF---VWSNGDWEFA--MILDGHNS------AES--V------ALVVN-TI----QNDYENIK-- 72 
Q47M61                4 RQASRRGVGANNEDRLG-------SGADWA--FVLDGATA------PAGVDSGcihdVCWLVD-RL----AEALSVTL-- 61  Thermobi...
jgi:Daci_4196        12 RGPSHIAEGLPNQDAWA---KFHHVWGDGI--VVSDGVGS------KPFSSFG----SHAACL-AV----EFAARACC-- 69 
CBJ80614             11 TGPAHLQNGLPNQDALS---ISGLRGGWSI--AVADGLGS------RPLSHIG----SRKAVH-LI----RHLAQRGQ-- 68 
goetting:HRM2_14750  11 RGVGHIIDNIPNQDAVL---TRQWEHGWLA--VVSDGMGS------RKKSDIG----SQCVCK-AA----LNVLKDAS-- 68 
Q82LD0              455 --ARLAED----------IRAARRgDLK--SGLHRltdrsl----------------------gklraSAAEQ-GV---E 494 Streptom...
jgi:Franean1_7181   112 --PASGAD----------LAALVR-AVT--GDID-----------------------------------AMLHsRA---S 138
Q0RFF7              247 ---REELT----------AADLLA-YAAryAESQ-----------------------------------AGAH-RL---A 273 Frankia ...
Q7NCD8              125 ltDPADPAave----hvaHAHFRV---------HLvetwrqmvaehlakkpvteaewqqleaaagpaaRFFQQ-HS---P 187 Gloeobac...
jgi:Cyan7425_0409    81 --SEQWTEqaiaqmaelaRETLPQ-HLV--QTWQStvladyqshpfraa------ewshlqarepglgEAEVR-DN---P 145
LANL:BG07_5066       73 --VLLEEP----------IEIAFR-SVE--NHILTlf------------------------------qSNSFQ-QAc--Q 104
Q47M61               62 --NTPMPL----------TDALAV-AIE--RVCY-----------------------------------AHGG-QCdlnN 90  Thermobi...
jgi:Daci_4196        70 --TGGEIE----------HNALFS-NIQ--ANWL-----------------------------------RLVA-PL---E 95 
CBJ80614             69 -----NLQ----------HSNIAQ-WLC--RDWL-----------------------------------AHFG-D----E 90 
goetting:HRM2_14750  69 ----FDTP----------DRDLVL-MIY--QRWL-----------------------------------NNLG-SI---N 92 
Q82LD0              495 PEEYSATLRCLLl--pADPecRT---RVFFGVGAGGL-FRL-RDGAWQD--I-E------PHV------ADATGEavvgF 552 Streptom...
jgi:Franean1_7181   139 GPDYLTTLLLGFvptvVAP--GGsvpAVVGRVGGLMA-WRI-RAGTVDP--VfSladpgsPGT------GGAPPQ----V 202
Q0RFF7              274 PREIGFVGAVAV----FAG--GR---CEIARVGDVSAfV-L-VDGEFHE--LlT------NAP------DEHVNV----V 324 Frankia ...
Q7NCD8              188 ETAYGSTALGVL----VTE--AY---LLFVQLGDGDMlCVD-AQGATSR--PfE------RDR------RFALNQ----T 239 Gloeobac...
jgi:Cyan7425_0409   146 LLAYGSTLLAVA----VTD--AF---LLYLQLGDGDIlQVD-RQGTTQR--AlA------KDS------RLIANV----T 197
LANL:BG07_5066      105 QVKGETACLICV----RKE--NY---IWWFSIGDCLVyVFHeELHKLGQymLnQ------RHF------YEWIGN----V 159
Q47M61               91 PDSPSATVALAR----RCD--DG---FDYLVLADTAVvFAQ-GDGTVQA--VsD------DRVdrlpggRPYSRQ----L 148 Thermobi...
jgi:Daci_4196        96 PRDCAATCLFAL----HLD--GV---IHLGMLGDGLAaIAK-SDGSVVS--LsE------NKT------QGFSNI----T 147
CBJ80614             91 YQAYETTCLWAWv---DAK--GH---GVAGQIGDGLV-LIK-SQGIFNV--LsG------VR-------AGFGNQ----T 141
goetting:HRM2_14750  93 PNDAVATCLIAWg---QSA--GQ---TRLFQLGDGAL--IF-HGQEQGQ--LsC------RHG------HAFSNE----T 143
Q82LD0              553 GSLPSEtPEGDRltmdlgittppspyepsprlsasleqggtpvepprdpfRFRASV--AhPGDTLLLCSGGLAEPL--RG 628 Streptom...
jgi:Franean1_7181   203 AALPGH--GDAL--------------------------------------EVRTVT--LsDGEVLALTTGGLASGV--R- 237
Q0RFF7              325 TDALPEqPLPEP--------------------------------------EVRRLD----AVRRVVLCTDGLATDL--RN 360 Frankia ...
Q7NCD8              240 TSLCLEeAAEET--------------------------------------RVCIWP--TpSPTLILIATDGYANSY--RT 277 Gloeobac...
jgi:Cyan7425_0409   198 TSLCTEaAWREM--------------------------------------QIQVLPltEqPPRLILLSSDGYANSF--VS 237
LANL:BG07_5066      160 NTFSLPvPCYSS--------------------------------------GARELR--Tg-RNRIVMVTDGVLEYGe-RR 197
Q47M61              149 VRESRNaPGGFWvastv----------------------------peaayEALTGT--Vr-GNEFALMSDGCS-RL--VD 194 Thermobi...
jgi:Daci_4196       148 TALSSKvSAKDW--------------------------------------QYLSLP--GeQCIAVLLCTDGVADDL--DN 185
CBJ80614            142 ATLAQA-APSEC--------------------------------------RSQRIEl-TqSGDGVLMMTDGIADDLvpES 181
goetting:HRM2_14750 144 TGLGISrRYSDW--------------------------------------ITKEVLl-GnNGQGVALMTDGISEDL--VL 182
Q82LD0              629 EPRLAEHLTARWSNGGPPG-------LAAFLA 653 Streptomyces avermitilis
jgi:Franean1_7181   238 GERVTGFLGPLWTVPPTP---------LEFLA 260
Q0RFF7              361 SPGVRSWLAESWETPGDVHa------MGEALR 386 Frankia alni ACN14a
Q7NCD8              278 EAAFESIGSEYLQFLRAQGidqlraeLPTVLE 309 Gloeobacter violaceus
jgi:Cyan7425_0409   238 EADFLQTGRDYLRWLEAEGmaavmnqLDGILS 269
LANL:BG07_5066      198 YENPIHLYKDIYE--NKVKlt---ecIQNVLE 224
Q47M61              195 YYGY--SWADVWNHLRAYGph----sLVDWVR 220 Thermobifida fusca YX
jgi:Daci_4196       186 ADGFVSSFAETHRTLAPVSan---rrIHEMLE 214
CBJ80614            182 LESFFDVIYQRQLRSNKRQmr---twLTKELQ 210
goetting:HRM2_14750 183 PDLFVPYMIKTMGRMSRRRgk---kwIRKQLE 211
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