3PA6,6HM4


Conserved Protein Domain Family
PTCB-BRCT

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pfam12738: PTCB-BRCT 
Click on image for an interactive view with Cn3D
twin BRCT domain
This is a BRCT domain that appears in duplicate in most member sequences. BRCT domains are peptide- and phosphopeptide-binding modules. BRCT domains are present in a number of proteins involved in DNA checkpoint controls and DNA repair.
Statistics
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PSSM-Id: 403825
View PSSM: pfam12738
Aligned: 39 rows
Threshold Bit Score: 65.6703
Threshold Setting Gi: 313754541
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3PA6_A         11 VVAYVEVWSSNGtenySKTFTTQLVDXGAKVSKTF-NKQVTHVIF---KDGYQSTWDKAQKRGVKLVSVLW 77   human
Q5TRD6         97 VITCFTGIRKKDe---LTHLVHLIHSMGGSIRKGM-DTKVTHLIC---NSSGGEKYRYAMTFRLAIIRPNW 160  Anopheles gambiae str....
Q9U7D8        117 VVTCFTGIRKKDe---LTKLVNLIHSMGGCIKKDL-NTKTTHLIC---NHSGGEKYQYAKTFRLTVVRPAW 180  fruit fly
KIS71862      599 LRLMLLGFDPDSp--eLYHAQKLVVEMGGSIITHWkAESLTHVVCatqESFEGKHAQHARSCGVPVVGLDF 667  Ustilago maydis 521
EDU48604      229 ITITPGHMPASL----RESLQRSVERIGAKISDNV-RIDTTHFVC---TEGRGPSWEKAVENNIPVVVPDW 291  Pyrenophora tritici-re...
XP_015018720   96 VIVYVEVRTGNDn--rSEGVKNIITKLGAQANDRL-LRNTTHVVF---KDGLLSTYKRAQSWNIPIVSILW 160  Drosophila mojavensis
Q7JUM5        187 IVVYVEVRTGNDn--rSEGVKSIIAKMGAQVKDRL-TRTTTHVVF---KDGLLSTYKKATEWNIPVVSILW 251  fruit fly
Q16W28        219 VCIYVEVRSGTDn--rSDGIRDHLVSLGAKVNDKL-YKDTTHVIF---KDGLLSTYQKAKKMNVPVVSILW 283  yellow fever mosquito
EDW32929      186 VVVYVDVRSGNDn--rSDGVKSIIADMGAQINDRL-LRNTTHVIF---KDGLLSTYKKAVEWKIPVVSVLW 250  Drosophila persimilis
ACH43665       27 isafVEVWSSSRtenySKTFEQQLLDMGAEVSKTL-NKHVTHVVF---KDGRLSTWKKAQKMGVKIVSVLW 93   zebra finch
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