1U7P


Conserved Protein Domain Family
Acid_PPase

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pfam12689: Acid_PPase 
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Acid Phosphatase
This family contains phosphatase enzymes and other proteins of the HAD superfamily. It includes MDP-1 which is a eukaryotic magnesium-dependent acid phosphatase.
Statistics
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PSSM-Id: 372256
View PSSM: pfam12689
Aligned: 32 rows
Threshold Bit Score: 183.968
Threshold Setting Gi: 121976750
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1U7P_A             3 RLPKLAVFDLDYTLWPFWVDTH------------------VDPPFHKSSDG---------TVRDRRGQNIQLYPEVPEVL 55  house mouse
Q23FY3             8 ILPKLIVFDLDMCLWSPETYVL------------------DEQPSKKIIGKlgnigegviGVQ-CGSQTLKLFPDVITIL 68  Tetrahymena...
XP_001697588       3 RIPKLIAFDLDGTLW--WPEMYml---------------dGGAPFRRDKSG---------AVFDKRNERIELMGASEEVL 56  Chlamydomon...
XP_001568012      15 LLPRVIVFDLDGTLWTPEMYQLw-----------------GGSPFKPHKQNl-------nSMIDKSGVEVRLIGESRDVL 70  Leishmania ...
Q386M6             5 PTPRVIVFDLDGTLWRPEMYELw----------------gGGAPFMLSKDNs-------sIAIDKKGTEVRLIGQTRELL 61  Trypanosoma...
Q4D0B5            59 SVPLVIVFDLDGTLWAPEMYELwg---------------gGGAPFRADPSDp-------nGAFDRAGTNVRLLGETRELL 116 Trypanosoma...
EEC50703          38 LIMKLAIFDLDYTLWRPEMYQLngpphltpiekvktrklkLSPAMLKEARTnle----dhVLVDRRGNLMRVFDGANYAL 113 Phaeodactyl...
jgi:MICPUN_57278  32 LLPSLVVFDLDDTVW--WPEMYm-----------------TAGNFHFEPPGs-------tRVVDRLGEELTIHPGARVAI 85  Micromonas ...
jgi:OSTLU_28230   65 SLPGLIVYDLDDTIWFPELYMI------------------AGAPFVKTSKS---------TVVDSGGARLGCYPAALASV 117 Ostreococcu...
XP_003057523      85 DLPALVCFDLDDTIWFPELYMM------------------RGAPWTKERCDttg----reRVMDASGEELRCYPAATAAM 142 Micromonas ...
1U7P_A            56 G-------RLQS------LGVPVAAASRTSEI---QGANQLLELFDLG--------------KYFIQ-REIYP----G-- 98  house mouse
Q23FY3            69 Qd------FYNNk----yPEVKLAIASSADTPfavQIAKNALNMLEILpgvtirqviqkgwqDNFDGhIQIGRtpplSsr 138 Tetrahymena...
XP_001697588      57 R-------ELATdp--kwKDTEIAYVSRTEYP---EWAIPCLKTFLVTpegqg----grnllDISAY-QEIYP----G-- 113 Chlamydomon...
XP_001568012      71 Q-------TLATds--kwANTYLAISSTCDVP---SWARELLGKFTFTdcagk----tvpmhDLFGDrIEIYK----A-- 128 Leishmania ...
Q386M6            62 Q-------MLSTte--ewRNTHLAISSTCDEP---RWAMELLQLFRFRdkrgn----dvpmlSLFGDlVEIYK----A-- 119 Trypanosoma...
Q4D0B5           117 Q-------KLSTdp--kwSSTSLAISSTCDEP---RWAMELLQLFQFTdssgr----rvpmlSLFGDlVEIYS----A-- 174 Trypanosoma...
EEC50703         114 E-------DIKRmet-dgHPIQAAAASRTDEP---SWARICMQHLALNdgt--------vlaEVFGDlVEISG----G-- 168 Phaeodactyl...
jgi:MICPUN_57278  86 E-------EMLNrprwrrANAQIAFASRTDEP---AWAMEAMRLLRVCtdprgr---dvtleDAVDH-AEVYPv---R-- 146 Micromonas ...
jgi:OSTLU_28230  118 AlakscgaFRE-------RGTLIAVASRTHRG---KWARELMDAFEVRdgddd----artlaACVDF-VDIAS----G-- 176 Ostreococcu...
XP_003057523     143 A-------MLRShaafakRGTKIAVASRTNRG---AWADEVMGMFVVDdgsgsg--ttttmrECVGDlVEMYS----G-- 204 Micromonas ...
1U7P_A            99 SKVTHFERLHH-----KTGV--PFSQMVFFDDENRNIIDVGr-LGVTCIHIRD---GMSLQTLTQGLETFAKA 160 house mouse
Q23FY3           139 KSKSHFPLLLK-----NTGI--AYTDMIFFDDCNWDDNCKHveLDCPGVVTQRtpnGLQLHEWNKALDNYQKK 204 Tetrahymena thermo...
XP_001697588     114 SKITHFKKIHK-----DSAV--PYEDMLFFDNEKWNCTECSr-LGIVCVYTPR---GLTREAWDRGLADFATA 175 Chlamydomonas rein...
XP_001568012     129 NKARQHEAILQkvnkiDPSVs-EYAQMLFFDNQTDNAQHVSr-IGVTAYYCPN---GMTEGTFQKGLDMWCCA 196 Leishmania brazili...
Q386M6           120 NKKNQHRTILKkvkehDPTVrgDFSDFIFFDNQQDNIGHVSs-IGVTSIYCPN---GMVGGVFERGLKEWRDK 188 Trypanosoma brucei
Q4D0B5           175 NKASHHRTILRklrekEIDVkeDFSQFVFFDNQTNNIESVSs-IGVTSVYCPR---GMVSGVFERGIQQWREK 243 Trypanosoma cruzi
EEC50703         169 SKVKHLQRLSH-----KTGI--RFEDMCFFDNEQWNIEDVSrsLPVKCYYTPN---GMTRQAWKDALKDSALE 231 Phaeodactylum tric...
jgi:MICPUN_57278 147 SKTEQFHRLKE-----KSGV--PFDEMLFFDNESRNVREVAa-LGVCCQYTPD---GMTVEHWREGLAKYEEH 208 Micromonas commoda
jgi:OSTLU_28230  177 SKTKHFARLRE-----KSGV--PYAEMLFFDNERENIDEVAr-LGVACVHCPG---GLSADAWRRGLTFFVDD 238 Ostreococcus lucim...
XP_003057523     205 TKKRHFEKLKA-----RTGI--PYADMLFFDNEEQNTRDVAt-LGVTCVLCVG---GMTERAWEDGLRAFAEK 266 Micromonas pusilla...
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