Conserved Protein Domain Family
TpcC

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pfam12642: TpcC 
Conjugative transposon protein TcpC
This family of proteins are annotated as conjugative transposon protein TcpC. The transfer clostridial plasmid (tcp) locus is part of some conjugative antibiotic resistance and virulence plasmids. TcpC was one of five genes whose products had low-level sequence identity to Tn916 proteins, having similarity to ORF13 homologs from Tn916, Tn5397, and CW459tet. This family of proteins is found in bacteria. Proteins in this family are typically between 302 and 351 amino acids in length.
Statistics
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PSSM-Id: 403745
View PSSM: pfam12642
Aligned: 30 rows
Threshold Bit Score: 95.9906
Threshold Setting Gi: 558526152
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
CGS-ASRI:BpOF4_21899  99 TRDFVSEYINISADEEEREQRLDELERYFVSGFDVSSLEDTSEFAGs-------RNVTSIRLLDIKRA-GQNE---ANVH 167 Bacillu...
CDA69612              94 AQNFTKEYLTY--ENRKEEEYKSRLKPYVTSGLLTGSLVDCTADAEa-------GYVQAYRIEDYTE--EQKD---VYVF 159 Clostri...
WP_014349608          58 AQEFVVTYLSSNDSQKE------RLAEFVADSSRMRLPKTG-------------RQVTDSAVVFVRRTdVQGSldiWTVT 118 Nocardi...
CAQ03328              95 AVGYVGAWLSSTRDDSA------SLSNYFAGSTLSLS-----------------TTPFEYRNIAVASLtPSTAgdlMTVV 151 Claviba...
EST18077             100 AQLYVAAYVEAGKGTEA------SLAPYYPLMRDISLQAEPGA-----------QHVDRLAAVRVTQA-SPGY---WSVT 158 Strepto...
EST17975             101 AARFARAYLGWDESKAAERE--QLLAAVLPPDTDTTMGWDGHGRQDv-------LAVQPGAVTTTKNAqARVR---VEVL 168 Strepto...
CBG71115             178 AEQYATLCLTYSPETASDRR--AALARYTSAGVDPECGWSGEGTRKalt---atWDGTSEKLPEYND------------- 239 Strepto...
Q82EW2                59 AEQYAMLCLTYSPDGASKRR--DSLARYASSGVDPECGWSGEGTSKavs---avWDGTSEKLAEYGD------------- 120 Strepto...
WP_015756992          59 ARSFAVEWATWNGNPDNYAQ---RTGLFLTK-------------VPtlpppsaiQEVTAATVLSVNLKdNDGY---SARV 119 Desulfo...
WP_015758013          58 AKAFATEWATFNGNNNEYNS---RLGTFLNK-------------TSsiiapvgiQEVMSSSLLASESKnSRDY---RVKI 118 Desulfo...
CGS-ASRI:BpOF4_21899 168 YLVAYDiketeevekevtkeeg------egedkkevtetvmeeeERVTSHDIEMVIPL-TTDGEG-FAITGYPSLANSH- 238 Bacillu...
CDA69612             160 AEVCYTgrslne--------------------------dgqtytTRETKNTVTLRVPV-YAKGGS-YIIEDLPLMVEDEs 211 Clostri...
WP_014349608         119 VSVRlg------------------------------------gsGNTAGARHFYRVAV-SLTEGR-LRALGLPAAVTPPg 160 Nocardi...
CAQ03328             152 VAADVKdeql------------------------------sdskKAPSWPRRYFQVAV-STSGST-LAALTLPAPVAGPg 199 Claviba...
EST18077             159 VAALITpssktgaasd-------------------ktqggsqdeAGAGPVLRYFQVPVkTAGTGGgYEAAALPAEVAAPa 219 Strepto...
EST17975             169 IRPVVEtepakdk-------------------------kkaetpAQDAARWVGLDVPV-AESGGQ-IVVTGRPGLVGIPk 221 Strepto...
CBG71115             240 -------------------------------------------------HGRYLGIQV-RTDDGG-LTTLTVPVYVKNLt 268 Strepto...
Q82EW2               121 -------------------------------------------------HGRYLGIQV-RTDEGD-LTTLTVPVYVKDLa 149 Strepto...
WP_015756992         120 LLHTHRlvpvtnagsvpitlvpvtredlarlqsnisldlsqqpaLSWQDFLLYVEVPV-KLVNKQ-PVVAGWPVIIAPDy 197 Desulfo...
WP_015758013         119 LLHVRRlspvegntnvpsslipvt--rddlvkikdsqydiqlpaIGWQNYLLFVEVPV-TVINNQ-PVIKGLPVIVSNNn 194 Desulfo...
CGS-ASRI:BpOF4_21899 239 ----MKstiqYe-------pSALEGA----DTTSQEREVLGD-FLTEFFTSYGISD-ETLAFMA------NVDRGLSHk- 294 Bacillu...
CDA69612             212 iyipEYktepYyg----------------nAVSDEKASAIKT-SVENFLKAYFEQDeSVINYYLggdcdkQKFTGLNGrf 274 Clostri...
WP_014349608         161 lgldL-----------------ATTYkttcPADAPVSTVASG-FLAAFLTGs-----GDITRYI------AQGSGITAla 211 Nocardi...
CAQ03328             200 st----------------tnAPPTDYpasvSTADPLGGSVMS-FLTSYLTGq-----GAVEPYT------SPNAGISAit 251 Claviba...
EST18077             220 tggeAPql-----------dYG---ApvpaDTHDPAVATISE-FLAAYLTGg-----GELDRYL------SPGTSLVAvs 273 Strepto...
EST17975             222 -------------------hGPKAPDtpttQTDPELSTQTEG-AVDKFFSAYAAGDtEAVTAPG------ASVPALPAgv 275 Strepto...
CBG71115             269 tgegIRiagdVgempmpprsDVPEVDrdseDVDTALGQQLQQtVLPGYFEAWAKSDrTTLARFT------AQGATLAAtt 342 Strepto...
Q82EW2               150 sgegMRvagdIgempmpgraNVPELDkddeVVDTSLSQQLQEkVLPGYFEAWGASDsTAMARFT------APGATLSAta 223 Strepto...
WP_015756992         198 prgvIeq---------------------snECKTLASAEFVT-FINQFMNMYYSG--QPLTNFV------MPGANVKPvf 247 Desulfo...
WP_015758013         195 kkgeIsq---------------------pkQYDGVVTPDFAT-FINQFMSMYFTG--QALSNFI------MSGSNIQPin 244 Desulfo...
CGS-ASRI:BpOF4_21899 295 -------------------vYQEHQIMESVK-DSDNGEFVVRVNVTYRdQETSIAAIHSFHMSISEENGRFFVQ 348 Bacillus pseu...
CDA69612             275 -------------------sFENIEKISCYQdTHNN--IVCIVEFKIKdAENNVKMLQKINLSMTESGGKFYIQ 327 Clostridium s...
WP_014349608         212 pppy----------tkadvvSVNADDSSCGK-SGSKIRVLASVTPS---AAGAEAAALEYPLTMINNGGQWQVQ 271 Nocardia cyri...
CAQ03328             252 papyt--------altpvsiTADAKPVAKPQ-DGSTAAVLATITTQ---NAVSQTLTATYALTLTARANRWEVS 313 Clavibacter m...
EST18077             274 papytkvs--vtqlaeqggdFAANAPVT----EGARRELLVDVAAT---GTDGQVRPLTYALALKARAGRWEIA 338 Streptomyces ...
EST17975             276 -------------------eYKGLVSWSADAgSGDSRTGTARVSWSLGgASVEQVYRVTITQVSSSDAHRWQVD 330 Streptomyces ...
CBG71115             343 glsgrlsepqvndvvalvpkGVQGSAPYSYK-TGQAVELRVVVDWA---DPEGDTARRSYRITVVNTAQGWFIK 412 Streptomyces ...
Q82EW2               224 glagrltgpkvgtaealvpaNVQDTKPYAYR-AGQSVQVRVVVDWS---EGESRIVRRAYRMTVVNTAQGWFIK 293 Streptomyces ...
WP_015756992         248 e-----------------wkLDSVNEVRVNN-EKNPTQACVQVLVS---APGVSKLTQVVYLKLHPTGGSYLVE 300 Desulfofarcim...
WP_015758013         245 g-----------------wnLLSIDEIKTDS-EK-PTKACVRVTVS---TAGIEKITQIIYIKVQAVRGSYLIE 296 Desulfofarcim...
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