Conserved Protein Domain Family
DUF3719

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pfam12516: DUF3719 
Protein of unknown function (DUF3719)
This domain family is found in eukaryotes, and is approximately 70 amino acids in length. There is a conserved HLR sequence motif. There are two completely conserved residues (W and H) that may be functionally important.
Statistics
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PSSM-Id: 403645
View PSSM: pfam12516
Aligned: 23 rows
Threshold Bit Score: 44.2948
Threshold Setting Gi: 196011946
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EGT53824      37 VFDGKELDD---PELNQEAMLWRDKFPHIRVIGiscgeHKVTHPA------------AVSPVSPNTLKSAMNHS 95  Caenorhabditis brenneri
XP_011482661 122 LYEGRGSGSgilPGLKEECQQWTMRFPHLRILG-----KQLLPPTdegfq--wyatpEGVTPADSPSTGKEnsv 188 Japanese medaka
XP_005474333 124 LYEGRGSGGgilQGLQDECQQWATRFPHLRILG-----TQLLCPSdegfq--wyttsGKGSASSRPSAGKEsgv 190 Nile tilapia
Q6NSV7       117 LYEQQLSAHt--QGLQKECQQWAASFPHLRILG-----RQIITPSegygl--yprspSAVSASHEATLSQERES 181 house mouse
XP_012656876 114 LYEQKLSMHt--KILQEECQQWTASFPHLRILG-----RQIIAPSeddgf--yprspT-VSASYEAPLSQERDS 177 small-eared galago
XP_002718468 115 LYERKLSVHt--KSLQEECQEWTASFPHLRILG-----RQIITPSedygl--yprcpSVLSASREATLPQERDS 179 rabbit
XP_023351132 115 LYEQKSSIHt--KGLQEECQQWTSTFPHLRILG-----KQIVTSCegygl--yprspSVISASHETTLNQEKES 179 Tasmanian devil
XP_002603051 120 LYEGRQKGN---QQIYNECKEWVSMFPHLRICG-----AQLLEPQdqgf-----rhipSEGTARPSTGTVVTDM 180 Florida lancelet
EDO26966      30 LFEGKGFNGs--SQLLLECQEWCTKFPHLRICG-----VQSVHPQdegtqyvplppdDPRVYNYRPQTSVLEDM 96  starlet sea anemone
XP_005005388   9 LYERKLSVHt--RSLHDECQQWTSSFPHLRILG-----RQIITPSegyel--yprspSAVSVSQEAVLSQERDS 73  domestic guinea pig
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