Conserved Protein Domain Family

pfam12515: CaATP_NAI 
Ca2+-ATPase N terminal autoinhibitory domain
This domain family is found in eukaryotes, and is approximately 50 amino acids in length. The family is found in association with pfam00689, pfam00122, pfam00702, pfam00690. There is a conserved RRFR sequence motif. There are two completely conserved residues (F and W) that may be functionally important. This family is the N terminal autoinhibitory domain of an endosomal Ca2+-ATPase.
PSSM-Id: 403644
View PSSM: pfam12515
Aligned: 28 rows
Threshold Bit Score: 51.1657
Threshold Setting Gi: 321438621
Created: 21-May-2020
Updated: 7-Aug-2020
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
Format: Row Display: Color Bits: Type Selection:
CBZ12380       39 GDDLFsDTG-ASSVSgrrsrsssvcrstEERGVLWTQVFPLHISVYLRVRDVVEVSQVCR 97   Leishmania major strain Friedlin
XP_003519080    6 npEEF-ELS-DKDRS-------------IEALEKWRSAAWLVKNPRRRFRWAADLVKRKH 50   soybean
XP_002867382   27 EDSPF-DIAsTKNAP-------------VERLRRWRQAA-LVLNASRRFRYTLDLKREED 71   Arabidopsis lyrata subsp. lyrata
XP_006585664   43 pDDPF-DITqTKNAS-------------HDTLRRWRQAA-LVLNASRRFRYTLDLRKEEE 87   soybean
XP_006648366   36 GADPF-DIP-AKRAS-------------VERLRRWRQAA-LVLNASRRFRYTLDLKKEEE 79   malo sina
Q70TF0         25 SHNPF-IIE-PKGS--------------IDRLKEWRKVT-FTVNAARRFRYTLDIKKFEE 67   Physcomitrella patens
XP_002961828   14 sKNTF-EIP-HKDTP-------------LEVLESWRKAT-LVLNASRRFRYTANVKKRRD 57   Selaginella moellendorffii
EFH54405        4 LLKDF-EVE-AKNPS-------------LEARQRWRSSVGLVKNRARRFRMISNLEKLAE 48   Arabidopsis lyrata subsp. lyrata
VDD15790        4 LLRDF-EVE-AKNPS-------------LEARRRWRSAVSVVKNPARRFRNIPDLDKRAQ 48   field mustard
XP_002284417    5 LKKDF-DVQ-SKHSS-------------EAALRRWRSAVTIVKNRRRRFRDVANLHMRSE 49   wine grape
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