Conserved Protein Domain Family
CopG_antitoxin

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pfam12441: CopG_antitoxin 
CopG antitoxin of type II toxin-antitoxin system
CopG antitoxin is a member of a type II toxin-antitoxin system family found in bacteria and archaea. Most antitoxins encoded by the relBE and parDE loci belong to the MetJ/Arc/CopG family of dimeric proteins which bind DNA through N-terminal ribbon-helix-helix (RHH) motifs. The toxin for CopG proteins falls into the family BrnT_toxin, pfam04365.
Statistics
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PSSM-Id: 372110
View PSSM: pfam12441
Aligned: 16 rows
Threshold Bit Score: 80.4613
Threshold Setting Gi: 497233169
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q30QH6          2 KTLPKFKDQNEEMAFWEKNDVTDFfdVKSAKVVRF-SKLKKSTKTIslRLPEDMLETIKVRANALDIPYQSFIKMLLQKE 80  Sulfurimonas d...
BAG01773        7 KSLPKFNSTEEIVNFFDSHDLGEF--ESELPEVNFdVDLKKKHYLV--AIDADLMVKLLEVAREQQISVEMLVNSWCRDK 82  Microcystis ae...
jgi:Ppha_2410   3 KKFPDFKTDDEAEAFVESADLSEYd-FSGMVPMRF--ELKRKDTSIslRLPEELLNEVRMNAKRLGIPYQRFMRLAIERA 79  Pelodictyon ph...
WP_015772950    6 KQMPSLRNDAEAEEFVAQADLSQYd-LSGFKPMQF--EIEPKAAALnmRIPVGLLEAVKAKAKAKGIPYTRYVRMLLEAD 82  Desulfomicrobi...
P72819         56 KPLPKMNSDQEAEDLLEQ-DLTDYlvPENFTKTTF--EFAPKDKSItlRLSSELLTAVKNTASAQGMNYQKYIREVLEQS 132 Synechocystis ...
Q9AAV5          3 KAVPKLTTDDEAEAFLTQ-DLSDLn-FSQFKPMRF--ELEKKEARVnmRLPEPLLEAVKKRASARGIPYQRFIREALETa 78  Caulobacter vi...
BAF72478        5 KKIPEFQNEEEERLFWEKHDSSEFidWENVRSVRF-PNLKKSTRSIslRLPEDMLERLKSRANAMDIPYQSYIKMLLQKE 83  Sulfurovum sp....
jgi:Gura_1395   6 KEVPAFSSEAEERTFWEQHDSTEYvdWSQAKRVTL-PNLKPTTQSIslRLPVSLLESIKSAANSRDVPYQSLIKIWLSEK 84  Geobacter uran...
jgi:Tgr7_3296   6 KTVPEFKSEAEERAFWETHDSSEYldLSQAVPTSL-PNLKPSTKTIslRLPVSLLERIKIEANKRDMPYQSLIKAWLAKD 84  Thioalkalivibr...
jgi:Pnuc_0291   6 KIIPKFKTEKEERTFWEKNDASEYfdLSKAVRVTM-PNLKPTTASIslRLSQSFLENIKLQANKLDVPYQSLMQIWLAEK 84  Polynucleobact...
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