Conserved Protein Domain Family
Peptidase_M57

?
pfam12388: Peptidase_M57 
Dual-action HEIGH metallo-peptidase
The catalytic triad for this family of proteases is HE-H-H, which in many members is in the sequence motif HEIGH.
Statistics
?
PSSM-Id: 403552
View PSSM: pfam12388
Aligned: 9 rows
Threshold Bit Score: 276.316
Threshold Setting Gi: 380729894
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
MPITM:COCOR_04566  51 VYVGRDTVVTLDASREML-QTDSDTREQYRTTNVISRDVKWIKIRVPA-----SAPATIRTGLNEAMKNFNDL-KLSFEF 123 Corallococ...
Q1DA81             51 VYVGGDAHVTLAASREML-QRGEGSKEHYMTTNIVGSSVTRICVNPTTe---fRSYVRLIQGLDMALANYNAL-GLRITF 125 Myxococcus...
jgi:Krodi_0018     83 IYIGEDIVVTAKELDEMT---VNQDTRQFRTNNLVTGANRTIDIIGYTgndnfGLSTKGRTALEWAVANFNRIsGSALRF 159 Dokdonia s...
EAP87052           76 IRIEGDIVMTKAELEELEfNGYSNENAQYSTNALV--SPQTITIIGYTgg-sqALTSSEQTALQWAVANYNRL-NLNINF 151 Croceibact...
Q1D8L5             61 VYVGRDAHVTLEASREML-QTDLKTQEQYRTTNLVAASITRICIVPNSa---yAANTTLMSALDRAIANYNAL-GLSFTM 135 Myxococcus...
WP_014399603       51 VYVGRDAHVSLESSREML-QTDQQTAEQYRTTNLVGTSVTKICVVPTAq---fNSYSRLSAGLDLAIENYNSQ-GLRITF 125 Corallococ...
MPITM:COCOR_03188  49 VYVGRDAHVTLEASRELLqPLEEGSAEQYRTTNQVGTS--VTKICVNPta-afNSYSNLSQGLDLAIANYNEQ-GLRLTF 124 Corallococ...
MPITM:COCOR_03090  51 VYVGRDAHVTLEASREMLqPATKETQEQYRTTNLV--ASTVTKICVNPts-gfNSYSRLSQGLDLAIQNYNQR-GL--SF 124 Corallococ...
WP_014395908       51 VYVGGDAQVSVDASREML-QSGGDSAEQYRTTNVINK-SLVRKICINPts-tfSSYSRLSQGLDLAIQNYNAL-GLCFTM 126 Corallococ...
MPITM:COCOR_04566 124 mpePidpCDRVpppcpgtgiMSTIDMVINPasPGGGGSSGGAP-SNGLPYPRFSISSSIASSPINTIEHVITHELGHVVG 202 Corallococ...
Q1DA81            126 v--R---GPAT---------GCTANITAKT--MAGSGHVAGFP-SGGLPYGAISIGTGLNSYGVDLNEHVITHALGHTLG 188 Myxococcus...
jgi:Krodi_0018    160 ---RltfGTNFnn-----sdMVVYDNTANN--PGQSGGVAGFPsAQGLPNKFVQI-YGLEGSSTNVNEHVITHEIGHSIG 228 Dokdonia s...
EAP87052          152 ---SltfGTNYqn-----kdMVVYNNTVNN--PSGAGGSAGFP-SGGNPHKFVQI-YGLSNYNTNVIEHVITHEIGHSVG 219 Croceibact...
Q1D8L5            136 ---Qr--GGSG----------CSATISART--MSGAGGSAGFP-SGGRPYGIINIGTGTATYGVAVVEHVVTHELGHAVG 197 Myxococcus...
WP_014399603      126 ---A-----RGsa-----sdCT-ATISAKT--TSGTGGSAGFP-KGGKPYGTINIGTGLQSYSVDVNEHVITHELGHTIG 188 Corallococ...
MPITM:COCOR_03188 125 a--R---GPTTg---------CTANISAET--TTGTGGQAGFP-SNGMPYGVFYIGTGLDSYSADVNEHVITHELGHAIG 187 Corallococ...
MPITM:COCOR_03090 125 ---TmarGPTTgc-----saNIT----ATT--MSGAGGSAGFP-SGGRPYGTINIGTGLQSYSVDVNEHVITHELGHAIG 189 Corallococ...
WP_014395908      127 v-----rGPSTgc-----naNI----TAAT--AAGTVYNAGYP-SGGLPYGTITIGTGWNTAPLDTVEHIITHELGHTLG 189 Corallococ...
MPITM:COCOR_04566 203 LRHSDFYNRSISCgGSAVNEGSaGVGAVLIPGTPNS-AtA-G-GSIMNSCIPTGSTGEFTSSDITALTYLY 270 Corallococcus coral...
Q1DA81            189 LRHTDHFNPSISC-GSGAMEPT-GTGALHIPGTPTG-A-T-PgGSIMNTCYPSGTDGEFTPSDIVALNFMY 254 Myxococcus xanthus ...
jgi:Krodi_0018    229 FRHSDYYDRA-SC-GSGGGESAgSTGAIQLPGTPT--R-D-F-DSIMQACFSNNEDGEFSSNDVTALRAMY 292 Dokdonia sp. 4H-3-7-5
EAP87052          220 FRHTDYFSRQ-SC-GQNTNEGTaGVGANHIPGTPTG-Y-D-S-TSIMLACFSSGEDGEFNSNDITALNYLY 284 Croceibacter atlant...
Q1D8L5            198 LRHSDYYNRSISCgGAATNEGTaGVGAIHIPGTPTT-A-TrG-GSLMNSCFGSSETGNFKSSDVTALQYLY 265 Myxococcus xanthus ...
WP_014399603      189 FRHSDYYDRSISC-GSGGNEGAsNVGAIHIPGTPTT-A-TrG-GSVMNSCFGSNESGEWTSSDRTALDYLY 255 Corallococcus coral...
MPITM:COCOR_03188 188 FRHSDYYNRSISC-GIGGDEGEaGVGAIHIPNTPTT-A-T-VgGSVMNSCFRSTETGEWTGSDITALAALY 254 Corallococcus coral...
MPITM:COCOR_03090 190 FRHSDYYNRAISCgGAASNEGTaGVGAILISGTPST-A-T-VgGSIMNSCFRSTETGEWTSSDITALNALY 257 Corallococcus coral...
WP_014395908      190 MRHSDYYSQVISC-GTGGSEGTaGVGAILIPGTPSTsY-V-N-GSIFNACLPANPTGEFTSTDITALTYLY 256 Corallococcus coral...
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap