Conserved Protein Domain Family
Haspin_kinase

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pfam12330: Haspin_kinase 
Haspin like kinase domain
This family represents the haspin-like kinase domains.
Statistics
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PSSM-Id: 403519
View PSSM: pfam12330
Aligned: 9 rows
Threshold Bit Score: 382.989
Threshold Setting Gi: 74675935
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_003667730 491 STS--NLSIHALTHRSSQSSLKHKVSHSSLQKFktrrrssnngtt---ganclnpnmddiSSHSSSINSNPLISLPTLDQ 565 Naumovozyma dai...
CCE93058     359 SSS--NLSINGLKHRSSQSSLKHKTSHSSLQRFktrrksn--------------ntggggDDCSSSNSQGPQISLPVPDQ 422 Torulaspora del...
XP_002498423 356 SSS--NLSLGNLKHRSSQSSLKHKSSQSSLQRFktrrksn-------------nmaeegsISSSGSHSHHPKISLPVVDQ 420 Zygosaccharomyc...
CAR23370     278 SSP--SYSSASLKTRLSQSSLKQKSSHSSLNKL---------------------------TSHHRNSVTSESISLPMPDQ 328 Lachancea therm...
CCJ29969      64 SGS--KLSPNCIGSIVKKASFLYKIS----------------------------------VKQDQENSPLNKLKKPLQNQ 107 Pneumocystis ji...
O13924       102 SKS--VVSKKEVVNLSSSVALSGK---------------------------------------------------PANNS 128 Schizosaccharom...
XP_010594812 395 VIA--ISSSESLLSEYSHPPIMNRTN----------------------------------SALSPWQSSSMYLLSPLKTL 438 African savanna...
1_pfamImport   1 SLS--IPVCETDVSGSSTHKIS--------------------------------------GYYSSWQASSMTILTPGSSL 40 
CCK69399     396 STSslSLSISSLKHRSSQPNLKHKTSHSSLPKFknrrqsntggddgsslltisssmnsvhSSHSNGTTNTNNISLPVPNA 475 Kazachstania na...
XP_003667730 566 --------------------VSRDKIQTKLRNSTSLLSLNSSHTVimtkKQHDTSILQ--QILQYC-DINYIInEY--DL 620 Naumovozyma dai...
CCE93058     423 --------------------VSRDKIRAKLRNSTSLLSLGSTTPVv--mKDYDEALLT--QLLELC-DIRHVVnEK--DI 475 Torulaspora del...
XP_002498423 421 --------------------MSRDKIKTKLRNSSSLLSLHSSLPIm--mKDYDEVVLQ--QILEYC-DVSKEL-PYddDY 474 Zygosaccharomyc...
CAR23370     329 --------------------VSRDKLRTKLRSSTSILSINSTVAT----EEFDEFQIS--QLLKLC-EQSQILpVE--QL 379 Lachancea therm...
CCJ29969     108 enimlhtfvstdkknhlekcLLKSQTKKKPSIMESLLSFASQSEI----FNFSDYISSllSTYTIS-KL----------- 171 Pneumocystis ji...
O13924       129 ----------------------------KLDPLHRLLQIVAQEDA----LPFSQFVKS--QTFEIQ-KI----------- 162 Schizosaccharom...
XP_010594812 439 -----------------------HIVDKKASDAEKVYGECNQEGP----VPFSCCLST--EKLEHCeKI----------- 478 African savanna...
1_pfamImport  41 -----------------------TFADLMATDEEKVYGECQQDGP----ISFGQCIPP--DKMKKCeKI----------- 80 
CCK69399     476 --------------------VSRDKIRAKLKNSASLLSLNSKIPme--kKSYDDNMLN--EILDLC-TVKCVIePA--EI 528 Kazachstania na...
XP_003667730 621 QSLHSNfnkhsiymltpqnSIKISSNIYKLRS-----KQAICKIIPL---------------GTPDDITTS-KITSL--- 676 Naumovozyma dai...
CCE93058     476 MASLAD-------------SRKLTSHVRSPRKn----EAVVIKKLPL---------------GTLEDVTYS-KEMCL--- 519 Torulaspora del...
XP_002498423 475 IPVLKN-------------ATELSTHVWRAQSe---gTNVIYKKLPL---------------ETLEDVTYS-KSMCL--- 519 Zygosaccharomyc...
CAR23370     380 VPEWNS-------------LQKLSKHVYRGEE-------SVFKVLPL----------------AQDDFTHS-KHLRI--- 419 Lachancea therm...
CCJ29969     172 -------------------GEASFSEVYLIKNk---nDEVVLKIVPFgkegq------edpqDVLHEVRVTlKMSSIng- 222 Pneumocystis ji...
O13924       163 -------------------GEASYSEVYQASNad--dVPVVWKVIPFgedgq------aqyaDVLNEVQIS-QWIKVdg- 213 Schizosaccharom...
XP_010594812 479 -------------------GEGVFGEVFQTITn---dTPVALKVIAIegrglvngshqktfeEILPEIIIS-KELSLlsd 535 African savanna...
1_pfamImport  81 -------------------GEGVFGEVFRTVGn---kRPVALKIIPIegtervngevqktfgEVLPEIIIS-KELSLlsq 137
CCK69399     529 DSKKHQhletl----ssnhSIQISQHVWRCTSsldqsQTIICKKIPL-----------------LCDFNEM--ESCL--- 582 Kazachstania na...
XP_003667730 677 ---------KELKMLHLVKGT-TGLPYLLQSYLLRSS-----------TGNISMYLYMKDKGTPLSTF--KFVNWDQVLN 733 Naumovozyma dai...
CCE93058     520 ---------QELKMLRLSKGT-TGLPWLLHSYVIREKieq------gnDTRLFLMLVLKNHGNPLSTV--NLTSWSQALH 581 Torulaspora del...
XP_002498423 520 ---------HELKMLRLSKGT-TGLPYLLRSFVIRERpifdeetasttEGKLYLLIILRDNGTPLSQI--KLNTWPQALK 587 Zygosaccharomyc...
CAR23370     420 ---------KELELLRLFNGT-PGFTQMCVCHLALVE------------NDPTLICELKYAGKSLAHV--RINSWAAALN 475 Lachancea therm...
CCJ29969     223 --------fVKSKGFAIVKGVyPEHLICLWDKYKKDFksenprpdfyrEDQHFCILLLEKGGKDLEHV--NIKSWKQVNR 292 Pneumocystis ji...
O13924       214 --------fANLHQVVVVKGTyPSLLLEEWDRYLMQNgsendrpdsysSTQLYCVLCLDHSGTDLEHF--ELRSWRECWS 283 Schizosaccharom...
XP_010594812 536 eahnrtegfIGLNSVHCVQGSyPPLLLRAWDHYNLTRgsandrpdffdEHQLFIVLEFEFGGTDLEQMrtKLSSMATAKS 615 African savanna...
1_pfamImport 138 ggtnrtegfIGLHSVHCVKGAyPKHLLCAWDQYDKLKgsennrpdffgDQQLFVVLEFEFGGSDLENMkkQLSSVATAKS 217
CCK69399     583 ---------KELKILKLCTGT-PGLPFLIQNYIIRSAd----------TNENTLYLFLKDMGDPITER--EVKNWSTCLK 640 Kazachstania na...
XP_003667730 734 IFWQCVNIMYVSETKFQFEHRNLILDHILIDSN-------------------------------------HNVTFINLKC 776 Naumovozyma dai...
CCE93058     582 IFWQCVTILYVAETKFQFEHRNLILDHILVDRN-------------------------------------LNVTLCDLKC 624 Torulaspora del...
XP_002498423 588 IFWQVVTTLYVAETKFEFEHRSLSLDHILVDDH-------------------------------------LNVTLCDLKG 630 Zygosaccharomyc...
CAR23370     476 IWWQCAVIIYAAETKFQFEHRDLQFEHVLVDAS-------------------------------------GNVTLCDYKL 518 Lachancea therm...
CCJ29969     293 IFWHIVKVLSEGEKKYEFEHRDLHWGNILVNEIfdssedllse-----------------lslynthfqqPCIIIIDYTL 355 Pneumocystis ji...
O13924       284 VFYETLKILSLVETRYEFEHRDLHWGNILIRKAdrseeevsfllneislddiesvdfpgsqdkaddfdniLQVTLIDFTL 363 Schizosaccharom...
XP_010594812 616 ILHQITASLAVAEASLHFEHRDLHWGNVLLKKTnlkelhytln-----------------gktgtiptcgLHVNIIDYTL 678 African savanna...
1_pfamImport 218 ILHQVTASLAVAEAALGFEHRDLHWGNVLVRRTnlkklqytln-----------------gktctiathgVHANIIDYTL 280
CCK69399     641 IFWQCALILYVAETKFQFEHRNLTLDHILIDKN-------------------------------------GTITLCDLSK 683 Kazachstania na...
XP_003667730 777 GRIKfdetlfpnsnSNTIEILSTRLD-HPLFFQGGGDYQFETYNLMRSLFNglnvtsgnnkddetIWDCFVPKTNLLWLH 855 Naumovozyma dai...
CCE93058     625 SRAQm---------GPNEPVIYTRLD-HPLFFQGGGDYQYEIYKLMRFILAet-----------cSWDSYEPRTNLLWLH 683 Torulaspora del...
XP_002498423 631 ARAYw---------ASRKETLFTRLD-HPLFFQGGGDYQFDVYNLMRAILSe------------tSWDNYEPRTNLLWLH 688 Zygosaccharomyc...
CAR23370     519 ARA-----------SQGSVVYYTRLD-HPLFFQGRGDYRYEVYNTMRHWCAd-------------SWARYDPRNNLLWLH 573 Lachancea therm...
CCJ29969     356 SRLRc--------nDHIGKLAWNNLE-DQEIFQGHGDYQYDIYRMMKDYVFsl----------nkSWSEFIPRTNLIHCK 416 Pneumocystis ji...
O13924       364 ARAS----------YSQGIISYNEFN-DPDLFNGVDDYQFDIYRLMSRVTKg-------------RWAQFFPITNVLWLH 419 Schizosaccharom...
XP_010594812 679 SRLE-----------RDGIVVFCDISmDEDLFTGEGDYQFEIYRLMRKENNn-------------CWGEYHPYNNVLWLH 734 African savanna...
1_pfamImport 281 SRLE-----------KEGLTVFCDIStDEELFRGQGDLQFEVYRKMKEENSn-------------NWAQFHPYSNVLWLH 336
CCK69399     684 ARANy---------YSNDNVIYTRLD-HPAFFQGGRDYLFDIYNSMRSIFIak----------neHWNHFEPGTNLLWLR 743 Kazachstania na...
XP_003667730 856 YIA---VKLLLNNN--NLPNSES--RIK--LNSIAQLSD--PATllpKNKNKYSRRNDHNINSCGDLL 912 Naumovozyma dairenensis CBS...
CCE93058     684 YLC---VKLFQRYE--NKLNKSGsaRDK--LSKLAQLVD--PSA---STKRGLFKRNEIDVKTCGDLL 739 Torulaspora delbrueckii
XP_002498423 689 FLL---YKLFHAYG--DKLVLQG--RER--LAALAQLLD--PSS---NARRSIFKRNEREVRSCGDLL 742 Zygosaccharomyces rouxii
CAR23370     574 YLG---VKLIESMN--D--VPHDgqYSE--LLKLIAQVN--PN----RRRKALFRRSDQ-ILNCGDVL 625 Lachancea thermotolerans CB...
CCJ29969     417 GLVrppTRLSKRTNsiNHADVEIerMFYerVESIWKTIN--------PKKKQFNGKNLLEFNSAEDvl 476 Pneumocystis jirovecii
O13924       420 YLI---HQLLHKKNl-SSPLTETetLMRsrLKQIFRLIDpvKTMqfqQAEDSIRSKST--VTSATS-L 480 Schizosaccharomyces pombe 9...
XP_010594812 735 YLT---DKILKQVTfrHKNNTSAmrQVKreIQQFHKTM--------------------LNYSSATELL 779 African savanna elephant
1_pfamImport 337 YLA---DKFLTAVSykRKPSSSAmkAVQqqLRQFLKTV--------------------LNFSSATEVL 381
CCK69399     744 YLA---IMLLTKNK--DR-TMMGpgRDQ--LLKLTVLLDmyPAAstkRSNHLFNKRKEIEIKSTGDLM 803 Kazachstania naganishii CBS...
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