Conserved Protein Domain Family
KBP_C

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pfam12309: KBP_C 
KIF-1 binding protein C terminal
This family of proteins is found in bacteria and eukaryotes. Proteins in this family are typically between 365 and 621 amino acids in length. There is a conserved LLP sequence motif. KBP is a binding partner for KIF1Balpha that is a regulator of its transport function and thus represents a type of kinesin interacting protein.
Statistics
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PSSM-Id: 403505
View PSSM: pfam12309
Aligned: 32 rows
Threshold Bit Score: 258.738
Threshold Setting Gi: 159115181
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_001707814 431 QDFIINCLTLQKYYTTNNIFRPSFTLIDVAEEVLFE--YGPKE------------------------------------- 471  Giardia lambli...
XP_019852056 227 IEWSLNAATISQYYINVSNYPQARHCLAAASVVLRS--YSEEL------------------------------------- 267  Amphimedon que...
XP_003442271 257 MEWALNAATLSQYYITKGRYMEGRHCLSAATVISDL--AGEVP------------------------------------- 297  Nile tilapia
XP_001181507 401 IDWALNCATLSQYYITQDDYTKARHCLASATRIFSE--AENKP------------------------------------- 441  purple sea urchin
EKC21399     227 LDWAINAATLSQYFVTKDEYPQARHCLACAEVIFEEiqFS---------------------------------------- 266  Pacific oyster
XP_009018983 230 LEWAMNAATLSQYYITIYDFTTARYCLASAETILKE--FGEKP------------------------------------- 270  Helobdella rob...
CDS36870     272 KDWANNTAALSEYYVETEEFGKALECLMTARTVVC--------------------------------------------- 306  Echinococcus m...
CBJ28687     358 GEWSRNACFLADYYSGLGRFTGAGRCLLAAQAVLQPegSAAAVptggkdnaslpppppargkdegeekgedggnaksggd 437  Ectocarpus sil...
XP_002499964 232 EEWAQNAAQLAGFYAARACWATARHCAAAAEKVFADanPGWKS------------------------------------- 274  Micromonas com...
CAG05689     263 LEWALNAATLSQYYVSKA-------------------------------------------------------------- 280  spotted green ...
XP_001707814 472 ---------RAQYVKDLpanenmpeddvaylqfrarqkvesvavirsilsldtarEVLAQIR--------------TERA 528  Giardia lambli...
XP_019852056 268 ---------GGKGEEMK--------------------------------------EKLEQSE--------------ADVS 286  Amphimedon que...
XP_003442271 298 ---------SEAAAQENetes-------------------------------errEHLRQKR--------------AEIA 323  Nile tilapia
XP_001181507 442 ---------IPEDMERDdrd--------------------------------arqENITSRK--------------ADIN 466  purple sea urchin
EKC21399     267 ---------ENENVSEDe------------------------------------kEKVQQGK--------------ADIQ 287  Pacific oyster
XP_009018983 271 ---------ASLKVPVTnadgqd---------------------------ainvlERLPKAW--------------ADLF 300  Helobdella rob...
CDS36870     307 -------------------------------------------------------ESFQNGDssglghnlngtklwADIS 331  Echinococcus m...
CBJ28687     438 sggatraggGGRETEKVstanerkre--------------------eeegteeerERRREQR--------------ADVD 483  Ectocarpus sil...
XP_002499964 275 ---------SEVDTSSSevegsiptg--------------------sghgvgaldDDALNVG--------------ANVH 311  Micromonas com...
CAG05689     281 ----------------Geaas-------------------------------eqrEKHRMQS--------------AHIS 299  spotted green ...
XP_001707814 529 RLYS----QILSNSyqrrellLEARREQMKIQYTSSEDLSNDDKELAHkqikavcqisqdecvssvrelydlllapdlea 604  Giardia lambli...
XP_019852056 287 RCWIkytiSLLTHS-------CTESGERGGGGGTREKVAIVHRFEPLE-------------------------------- 327  Amphimedon que...
XP_003442271 324 RCWIkyclNLLQDAkk----qLEDNIGELDTDRQEELKRARRREEEEEekgrksall----------------------- 376  Nile tilapia
XP_001181507 467 RCWIkyciSLLQFSkehelngTLENASSTPSASNDRRETPSIAQDEQTecgteedkl----------------------- 523  purple sea urchin
EKC21399     288 RCWAkyglALLEFSkd----rLLKATEEDTPLDPDESEKEFEKFNLE--------------------------------- 330  Pacific oyster
XP_009018983 301 RCWSkyslVLLEHSrd----sLMEKSKDDEISNIQNSSAECNSKKEffn------------------------------- 345  Helobdella rob...
CDS36870     332 WLTSeyslGLLEGGskvvlgsRFTIDPELVDTSPSYGSLFNQDTTKALqeayg--------------------------- 384  Echinococcus m...
CBJ28687     484 RHMAklyiTVLQAKhl-----eLGRGGGAGGEFCKVRTREEEEEEEGLvagfas-------------------------- 532  Ectocarpus sil...
XP_002499964 312 LAWAklhlRRLTAAte----lFATRGATETGAGGEAKRAASTGDDNALivsfptl------------------------- 362  Micromonas com...
CAG05689     300 RCWIkyclNLLEDAkk----lLEDNAGELDTDHQDELKRARRLGEEEEeksrksall----------------------- 352  spotted green ...
XP_001707814 605 tleaaakrqlrklglqtkgdvDPESEtDEKSGEKVTTpklq---nlfLAEplVRTLFYDSYRQFIAASRYFILDGFVTDH 681  Giardia lambli...
XP_019852056 328 ---------------------LADVE-GQVSCDVVEN----------YQD--ASKVFLFAEAQIKLAQKFYNLEDHATDF 373  Amphimedon que...
XP_003442271 377 ------------fgsedtfdsIASIE-EKVMCLFPLD----------FTE--ARSVFLVGQNHVTQAKDYFQMDGYVTDH 431  Nile tilapia
XP_001181507 524 -------------adrfesleLTSLE-SQVRDEVVRT----------FDE--ARSLFLPAQKWINAAKEYYVIDGFVSDH 577  purple sea urchin
EKC21399     331 ---------------------VTSRE-EQITCKPVRD----------FEE--ARNVFLRVQTWISGAKEFYVFDGRCTDY 376  Pacific oyster
XP_009018983 346 -------------------leTTSAV-NQITDRRVLV----------FDE--AKQVFLQTQSWLNSAKEFYCLDDHCSDY 393  Helobdella rob...
CDS36870     385 -----------------epiqDTGLT-TMISELSIMPk--------aYPA--AARLFRWTCRSLSEALLYYRLDERCTEA 436  Echinococcus m...
CBJ28687     533 ----------------lgigeLPMCDpAGVPGD--------------FES--VRDVFKRAKSHTERALRHYVLDGFVTAH 580  Ectocarpus sil...
XP_002499964 363 ---------------rlgdggATSATeAAKTVGIVSQgpgegwvprdLAT--ARAVFNQAARRFRAALARYKLDGFVTEH 425  Micromonas com...
CAG05689     353 ------------fgsedtfdsIASLE-EKVPCLFPLD----------FSE--ARAVFLVGQSHVKKAKEYFQMEGHVTDH 407  spotted green ...
XP_001707814 682 CQILLDISTLHQIYAYYEEarldfltnsatseeaekvSYTPLIKLHTRRCTTLEKVIPELSLDHYSKLIASLQVEVAEAR 761  Giardia lambli...
XP_019852056 374 VSISQDHSSLYKILSFFES------------------DLSLKCRMHKRRVDILSSLLSCLNPQYYLVLNRQLMFELGDTL 435  Amphimedon que...
XP_003442271 432 IEILQDHSALFRSLAFFEE------------------DLERRCKMHKRRVDMLEPICNDLNAQYYLMIRRQLMFELAETY 493  Nile tilapia
XP_001181507 578 IELVKDHSQLFKLISFFEI------------------DFERRCKMHKRRVDMLADMLDGLNRQHFLTICRQLMFELAETY 639  purple sea urchin
EKC21399     377 IELVQDHSKAFKLLAFFEL------------------NLDRQCKMHKRRADMLLEVCNELNPQHYLLIVRQLIYELAEIY 438  Pacific oyster
XP_009018983 394 VDIVKDNSTLFKLLLFFEP------------------DLTRQCKMHKRRADMLTEILHLLNPQFYLDVCRQLAFEIGEVF 455  Helobdella rob...
CDS36870     437 IKLIRAHASAYGYLATFEA------------------DLPRKCCMQKRRVDLLEDLLAQLNPRFYMLSCRTIMSECAEAL 498  Echinococcus m...
CBJ28687     581 VALHQGLSRAYLYLSGFER------------------DAKRRQAMCTRRAQALEPLLDALARKAYARLHKELSFELGEIY 642  Ectocarpus sil...
XP_002499964 426 CDVVLDVARLHKHLAFFEEs-----------------NPRRYNSLQRRRAERCERVAAELSRDKYPGLYKTLWFEYAEAH 488  Micromonas com...
CAG05689     408 VEILQDHSALFRTLAFFEE------------------DLEARCKMHKRRIDMLEPVCNELNAQYYLMIRRQMMFELAETY 469  spotted green ...
XP_001707814 762 TAIYHIVsrdiacnpyLKRLTEDMeyAAQLQLKQidplpdkdsvliSTVAAHCSRAIEAWRAVCKTYead---sraRLLQ 838  Giardia lambli...
XP_019852056 436 NDMANNK---------IILASEEG--SSPSQHQI------------QKINRLLNDAIKHYGEFFSSF---------ETQP 483  Amphimedon que...
XP_003442271 494 NEMMDLK---------LALANRQAdtQSLDNHTI------------KKFNHLCSASAKYFQMFLDSLcs-----peGKFP 547  Nile tilapia
XP_001181507 640 SEMMDLK---------IALAEKQ---RVPPTHKVa-----------SKINVLCKQSLTYYQDFIHSTkd-----heGKLP 691  purple sea urchin
EKC21399     439 SGIMDIK---------YMILKEEG--GQPSIHAI------------KKINSLALQSIQKYQAYIDSFkd-----nkPDLP 490  Pacific oyster
XP_009018983 456 TAILDNK---------LALLELTGsaRMCDGHAN------------NKINILAKKSIEYFQLYLSYLkk-----ndKTFP 509  Helobdella rob...
CDS36870     499 TALRDLN---------EEKMKRTTirASPTSSLSstnivaelsklaKKVNGLGLRALEMYKRLLDSFltp----anQREP 565  Echinococcus m...
CBJ28687     643 QDLADIK---------TLRAEEKLksGGTRAPTAlas-------dlRGANKLLKSAIGFFSHFVAMYhegdpsggsAESP 706  Ectocarpus sil...
XP_002499964 489 RAILEGK---------IRRGRPP-----------------------LSLGDAARCATRGYTAYVDTFedqv--gsdRLNP 534  Micromonas com...
CAG05689     470 DEMMNLK---------MIRANTQAdtQSLDKHSI------------KKINHLCSSAVKYFQMFLDSLrs-----ldGKFP 523  spotted green ...
XP_001707814 839 EYhfkrkefskDEIMKFLtfddrdsmqTCIFETAKLLSQ-LPTCDPVIKHGLLADSLRCFEQVQKLWLD-NENL------ 910  Giardia lambli...
XP_019852056 484 EA---------EYLHSYL---------TSKLNVARLYSK-LLAGNPGEQIKNLETSIQSYKWLIEYCEShTEEI------ 538  Amphimedon que...
XP_003442271 548 ERle------eEVLRPAL---------VARFRVARLHSR-LISTSPTVQLDNLNKSLENYKYVVQYCEA-NPEA------ 604  Nile tilapia
XP_001181507 692 DKfe------sDVLRPVL---------VAYFCVGRLYSK-FVTPSPPERLDYLQLSLDSYKAIVDYCDK-NPDH------ 748  purple sea urchin
EKC21399     491 DEyp------eLDTRPIL---------VAWFCMGRLYSK-ILPLNVRERLDNIKKTEACYQYIIDYCKR-HHKA------ 547  Pacific oyster
XP_009018983 510 ETfq------dDDERPAL---------IAHFHCGRLFSK-ILTASPKENLQNTKNSLDCYNFLVEYCRK-NPSA------ 566  Helobdella rob...
CDS36870     566 DLye------eEWLPHVL---------MAHFYSARLHSKtIIAGAPRNRVGELHLAMKAYEKMVEIADKhARSG------ 624  Echinococcus m...
CBJ28687     707 SQpakg--mepDEAVGYL---------QARFMRARLNGK-LRPLTSEKELHALRVSCGEFAWLSEHARGhLKSVretagd 774  Ectocarpus sil...
XP_002499964 535 RRii-----dsDEEKTYV---------TARFIRARTASK--QHGQFGSEADALGVALIDYEFVPAYVKA----------- 587  Micromonas com...
CAG05689     524 EKle------eDVLRPAL---------VARFRMARLYSK-LICSLPSAQLENLNESLDNYMWVTRYCED-HPEA------ 580  spotted green ...
XP_001707814 911 HKKETS---LKLIGTTIDLLREKIGR 933  Giardia lamblia ATCC 50803
XP_019852056 539 KEVFTEe--LGLCKEMVALLPQKIEL 562  Amphimedon queenslandica
XP_003442271 605 GAAVETe--LELSKEMVGLLPLKINR 628  Nile tilapia
XP_001181507 749 KDTVKDe--LDLCREMTELIPLRMAN 772  purple sea urchin
EKC21399     548 AECMRAe--LEVCEEMVALLPLKMEK 571  Pacific oyster
XP_009018983 567 AKKVKEe--RDACEEMVKLLPGKMDK 590  Helobdella robusta
CDS36870     625 YKVDMPe--VEIAREMTQLLAGQIAR 648  Echinococcus multilocularis
CBJ28687     775 PGIFEQe--LELAEEMAQLQRRNIAN 798  Ectocarpus siliculosus
XP_002499964 588 HGLVGMeqeSDLCEQMCALLPTKIVH 613  Micromonas commoda
CAG05689     581 AAAAETe--LELSQEMVELLPFKINR 604  spotted green pufferfish
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