Conserved Protein Domain Family
CD99L2

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pfam12301: CD99L2 
CD99 antigen like protein 2
This family of proteins is found in eukaryotes. Proteins in this family are typically between 165 and 237 amino acids in length. CD99L2 and CD99 are involved in trans-endothelial migration of neutrophils in vitro and in the recruitment of neutrophils into inflamed peritoneum.
Statistics
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PSSM-Id: 403499
View PSSM: pfam12301
Aligned: 13 rows
Threshold Bit Score: 100.992
Threshold Setting Gi: 301623488
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_015217208  51 FNLGDVF----D--MPGPTKP----------------------------PVTPKpk---------------kP------- 74  spotted gar
2_pfamImport   1 FDLADAL----DevNPTTPTPkpaapgggkg--------gatkapskvtPKAPVt----------------tPvkpk--- 49 
6_pfamImport   1 FDLSDAL----Dt---dDDKP----------------------------SLTPKpp--------------kkPdtn---- 27 
NP_001073449  54 FDLSDAFe--sD-----PKKP----------------------------AVVPPksvd----------dkkkPa------ 82  zebrafish
XP_007248173  57 LDLADVFgdddDdyKPPTRKP----------------------------PVQPVqp--------------kdPvkpk--- 91  Mexican tetra
ELK18130      24 FDLRDAL----KetASVKQKWdyt----------------------tttTKRPGtt--------------raPakp---- 59  black flying fox
XP_003918459  30 FNLEDAV----KetSSIKQKWnqv----------------------tttTKRPVtt--------------raPant---- 65  olive baboon
Q8BIF0        30 FNLEDAL----KetSSVKQRWdhf----------------------sttTRRPVtt--------------raPanpaerw 69  house mouse
XP_005991910  30 FNLEDAL----EdpTEKPKAPvtprptk--------------gllttttTKAPKvtqpdfslldilstttkkPkgtkap- 90  coelacanth
5_pfamImport   1 FDLADYF----DspVEPTSKParptarp--------------dvvrtttTKRPKtt--------------qaPrkqn--- 45 
XP_005463722  22 FNLFDAL----DdkTPTPQKP----------------------------KEKPKat--------------eqPk------ 49  Nile tilapia
XP_002941047  24 FDLDQAFd---Dd-vDVTTKP----------------------------PLAPTkntv----------epkkPtpkpn-- 59  tropical clawed...
XP_015206936  25 FDLADAL----Dd---KPTKPptvkpnpkvpggssdfdfdfdfpakkttTKAPKvttt----------ttkaPpkpk--- 84  spotted gar
XP_015217208  75 ---------------------SGDEFDLGDALggpd--------------------------phpTKQPAVPPKNPGKG- 106 spotted gar
2_pfamImport  50 -----------------pkpaAADDFDLSDAL---------------------------------DSNNDIGIKDKNKGq 79 
6_pfamImport  28 ----------------------dnDLDLSDALggedp-----------------------------ftkapPVVKPNPGg 56 
NP_001073449  83 ---------------------SGGELDLSDAFg-------------------------------pDTETKKPMVPPKERe 110 zebrafish
XP_007248173  92 -----------------pkpdA--DFDLSDAL---------------------------------DPSNDIGGKGKDTGk 119 Mexican tetra
ELK18130      60 ---------------------agSDFDLSDAW---------------------------------DNPND-RFDGHRKPs 84  black flying fox
XP_003918459  66 ---------------------lgNDFDLADAL---------------------------------DDRND-RDDGRRKPi 90  olive baboon
Q8BIF0        70 dhvattttrrpgttrapsnpmELDGFDLEDAL---------------------------------DDRND--LDGPKKPs 114 house mouse
XP_005991910  91 ----------------pkkntDPLDFDLSDALv--------------------------------DNDDGIGSKGKDNR- 121 coelacanth
5_pfamImport  46 ------------------pgkNPLDLDLADALgdrvalgqpa-------------hatatstcqvDPQHQ-KEYGCGVGt 93 
XP_005463722  50 ---------------------KDGELDLLDAFgpdepqpekpkkpssgdsdlngfnlgdalnpgpTTKPDKPAVNPPKGg 108 Nile tilapia
XP_002941047  60 -----------------pggaD--DFDLGDAFgh------------------------------dDKGKETPKPKPGGGa 90  tropical clawed...
XP_015206936  85 ------------------pkqaSDDLNLADAL---------------------------------DENNDIGGKDQNKNg 113 spotted gar
XP_015217208 107 -----------------------GSFDNDDLGYVAGEGD-YNPD---KGKSGGRSGGR-AE------GDTqGGSDQPQAe 152 spotted gar
2_pfamImport  80 gdkiktd---------ndptfqsRGFSDNDLFDVSKDET-YHPD---KGKGGRPSGSKdQLd-----QYD-ENSDTTAE- 139
6_pfamImport  57 s--------------------gsSGNLDDSLFNIAEGGDgYKPDenkGGGGGGGGGGRgRKvspgdsSDTnPGSNEGQS- 115
NP_001073449 111 t--------------------ggRSFDDNDLIDVSERGG-YKPD---GGGSRGRGGAP-SS------DDQsGGAEQPQG- 158 zebrafish
XP_007248173 120 gdkslggggrgdgrpnirggnggGTFTDDDLFDVGNDNS-YKPD---KGKGGRGSASTdLD------SNDnGDYDTMAE- 188 Mexican tetra
ELK18130      85 a--------------------rgGGFSDKDLEDVL-GGD-YKPD---KGRGDGRYGNNd-----------dSEAGMSPE- 127 black flying fox
XP_003918459  91 a--------------------ggGGFSDKDLEDIVGGGE-YKPD---KGKGDGRYGSDd-----------dPGSGTVAE- 134 olive baboon
Q8BIF0       115 ag-------------------eaGGWSDKDLEDIVEGGG-YKPD---KNKGGGGYGSNd-----------dPGSGISTE- 159 house mouse
XP_005991910 122 -----------------------GDFSDDDLKDVIAGG--YTPD---KNKD----GSNdPArgggnvEDPsKGYDNTAE- 168 coelacanth
5_pfamImport  94 gs-------------------ggNTDSQGRAMGAARGAG-HN----------------------------------RVE- 118
XP_005463722 109 g--------------------ggGNFDDSDLDDVSGGD--YKPD-------GGRSGgr--------aMDPqGGAEQPQg- 150 Nile tilapia
XP_002941047  91 gga-----------------vdgGTISDDDLFDPAGKPL---PDd-pKDREYLPS-ADe------------GQNDEQPK- 135 tropical clawed...
XP_015206936 114 dkgvvpgsrg--ddgptggdkkgGTFTDEDLEDISKGGG-YSPD---KKPDRGRGSASsD---------DtNY-DSTAE- 176 spotted gar
XP_015217208 153 gSGKIAGIVSAVGVALLGAASSYFAYQKKKLCFKISGG-----DPES--GNKTQSGTQSEP 206 spotted gar
2_pfamImport 140 -VGTIAGIASAVAMALVGAVSSYISYQKKKLCFGLQQSl----NADMvkTENPEAVVATEP 195
6_pfamImport 116 -SGSIAGIVGAVGMALLGAASSYFAYQKKKLCFRGSG------NQESvnMEA-QNKAHLEP 168
NP_001073449 159 --GALAAIISSVGVAVLGAASSYFAYQKKKLCFKVQGGe----DPESgkSHG------TNS 207 zebrafish
XP_007248173 189 -TGTIAGIVSAVGMALVGAISGYISYQKKKLCFSIQQSl----NTDMvkAENPEVVVAQEP 244 Mexican tetra
ELK18130     128 -TGTIAGVASALAMALIGAVSSYISYQQKKFCFRIQQGl----NADYvkGENLEAVVCEEP 183 black flying fox
XP_003918459 135 -TGTIAGVVSALAMALIGAVSSYISYQQKKFCFSIQQGl----NADYvkGENLEAVVCEEP 190 olive baboon
Q8BIF0       160 -TGTIAGVASALAMALIGAVSSYISYQQKKFCFSIQQGl----NADYvkGENLEAVVCEEP 215 house mouse
XP_005991910 169 -TGTIAGIVSALAMALVGAVTSYISYQQKKFCFSIQQSl----NAEYvkGENMEAGIAEEP 224 coelacanth
5_pfamImport 119 -TGTIAGIASALAMALVGAVSSYISYQQKKFCFSIQQGl----NAEYvkGENMEAVVSEEP 174
XP_005463722 151 -SGPIAGIISAVGVALVGAASSYFAYQKKKLCFKLQGGa----DPESgkGHQgthsepqvl 206 Nile tilapia
XP_002941047 136 -SNLIAGIVGAVGAAAVGAVSSFIAYQKKKLCFKESNGdpenvNMESykGDQ------AEP 189 tropical clawed frog
XP_015206936 177 -TGTIAGIASALAMALIGAVSSYISYQQKKFCFSIQEGl----NAEYvkGDTLEAVVAQEP 232 spotted gar
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