5D6T


Conserved Protein Domain Family
Spherulin4

?
pfam12138: Spherulin4 
Click on image for an interactive view with Cn3D
Spherulation-specific family 4
This protein is found in bacteria, archaea and eukaryotes. Proteins in this family are typically between 250 and 398 amino acids in length. There is a conserved NPG sequence motif and there are two completely conserved G residues that may be functionally important. Starvation will often induce spherulation - the production of spores - and this process may involve DNA-methylation. Changes in the methylation of spherulin4 are associated with the formation of spherules, but these changes are probably transient. Methylation of the gene accompanies its transcriptional activation, and spherulin4 mRNA is only detectable in late spherulating cultures and mature spherules. It is a spherulation-specific protein.
Statistics
?
PSSM-Id: 403383
View PSSM: pfam12138
Aligned: 90 rows
Threshold Bit Score: 119.698
Threshold Setting Gi: 74613881
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
?
Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
5D6T_A             33 YVYPA---PGA-----WDPLedvi--------skhPDVNFTVVINPGSGPGpealpDgn-ytREIPKLaSYENVRLLGYV 95   Aspergill...
jgi:Ajs_0766      153 YFSAG---PGSd----WEKLasga--------qsfPAVPITAILNPSNGIFtk--eDpl-ftAAITAF-RQNGGKVLGYV 213  Acidovora...
jgi:Cha6605_2766   50 YIYPN---WYAknnyvWKQVla-----------aaKKVQIVAIINPNNGPDna-ppNvd-yqQGIKDL-RQAGIKVIGYV 112  Chamaesip...
XP_002970976       51 YFDPS---SNSq---aWSSLnsaa--------ttlPN-RVVAIANPSNGPGsa--aQss-yqNVITAL-QRQTGLVIGYV 111  Selaginel...
CCH31850           39 Y---------------WSPAdpdglttfrrlaqnrPTTGLVVLNGSLSRPEa---pFspawaEAIEAV-HDSGARVLVYV 99   Saccharot...
Q5AV17            103 YIHPLa-dPAA-----WNRIig-----------ypSNIVSVLIANVLNGPDtt--vNea-waDVINRA-SASGKRIIGYV 161  Aspergill...
EHA25772           24 YINPLs-dPAA-----WDRLid-----------ydAKKMPILVANVVNGPDst--vDsn-weDVIKRA-SSAGKTVLGYV 82   Aspergill...
EPS26948          481 YINPLa-dPSA-----WDRLvg-----------ysSSKMPILVANVMNGPDsv--vDdh-wtDVIQRA-AGSGKTVLGYV 539  Penicilli...
GAA87228          457 YINPLs-dPTA-----WTRMid-----------ypSDKVTVLVANVLNGPDtt--vDed-weKVISRA-NAAGKRVLGYV 515  Aspergill...
CBN79566            8 YIYPLrddSLAr---eWQEMkdag----------dagVSVVAIANPGSGPGte--gDrgpysKGMQAL-RDSGVEVIGYV 71   Ectocarpu...
5D6T_A             96 ATTY------------------AKRNISEVRRDIETYAAWPTqssnaNLAVRGIFFDETPQq----------yDADILAY 147  Aspergill...
jgi:Ajs_0766      214 YTRYg----------------tGARSVADIQRNIDNYRKIY------GTQVDGFFLDEMDA------------TSKQLGF 259  Acidovora...
jgi:Cha6605_2766  113 PSNY------------------ASRDLQAVKADIDLYLKYFN--------VDGIFIDEAAN------------KQDKLDY 154  Chamaesip...
XP_002970976      112 STNY------------------SNRASNLVQDDVDTWYRFYP-------TINGIFFDEVAN------------TDGEQPY 154  Selaginel...
CCH31850          100 DTGYfgvdlgqgahqtrngettPEAWAAQIRQDVDEWYALYG-----GYGVDGVFLDQVLHvc--------gpDGEYAAR 166  Saccharot...
Q5AV17            162 RTGYlgqsqqrf--etrlgsteIADWVAQIEADVDLWYALY------PGKIGGIFFDEALNic--------gsNNEYADL 225  Aspergill...
EHA25772           83 RTGYlgvsdqkf--htrlgsgdLADWTAQIEEDVDMWYKLY------GDSIGGIFFDEGWPec--------gdNNQYVDL 146  Aspergill...
EPS26948          540 RTGYlgvsqqkf--vtrlgsgdLADWTAQIEEDVDMWYSLY------GDKIGGIFFDEGWPec--------gaNNEYVDL 603  Penicilli...
GAA87228          516 RTGYlglsqdqf--qtrlgssgLADWVSQIQTDVELWYTLY------PGMIGGIFFDEGWNqc--------gdDNVYSDL 579  Aspergill...
CBN79566           72 ASGY------------------GRRSEIQVKADIDRYKEWY------GEWLSGIFLDEAACvfddasdgdgamCARYRGY 127  Ectocarpu...
5D6T_A            148 LRELTDVVKGtsGl------gPDHYVVHNPGAI--PDSR-YL----STADST------VVFEA-------TYATFQERhg 201  Aspergill...
jgi:Ajs_0766      260 YREIYQYIKGldS---------RLRVVGNPGTYpvADSA-------SVVDAL------VSFEGqa----vDYRSVTPQpa 313  Acidovora...
jgi:Cha6605_2766  155 YHQIYRYLKShsPssdnnnraIEYTLIINPGTD--VNED-FIr--qPVADAI------VTFEN-------YRSVWTKYsp 216  Chamaesip...
XP_002970976      155 YQSLYNYVKSknS---------SSLVVNNPGAP--TLETyLFyngsRVADVI------CIFESgvgglsmTQSSWTSK-- 215  Selaginel...
CCH31850          167 YAALRDHVLAthP---------HAHVAINPGTD--TEQC-YD----GVADTI------LSFEG-------DHGSYLAHvp 217  Saccharot...
Q5AV17            226 YRFLSDNTKRkyS---------NAFTVLNPGAT--IPQC-FE----NSADTL------MTFEQ-------SFDVYINSyv 276  Aspergill...
EHA25772          147 YKYINAYTKRahP---------GALTVLNPGSP--MASC-FE----DTMDTL------LTFEL-------SYDSYVNSyt 197  Aspergill...
EPS26948          604 YKYINAYTKRahP---------GALTVLNPGSP--MASC-FE----DTMDTL------LTFEL-------DYTSYKNSyt 654  Penicilli...
GAA87228          580 YRFITDYTKRmhP---------GAFTVLNPGAT--MPQC-FE----HSADTL------MTFEN-------SYDTYMNNys 630  Aspergill...
CBN79566          128 HQRIRELMGDsaT------------VVMNTGSM--ITEK-AL------TDALgpdvvwNVLEN-------SRSSLEKDfg 179  Ectocarpu...
5D6T_A            202 ---aELFdti---------------------------------------pdSHRDQLCAVIHSVPtSVEG--SDlrgLVK 237  Aspergill...
jgi:Ajs_0766      314 n-kwVYN--------------------------------------------LANGAQAALVHDAAnCGAMq-----eVLR 343  Acidovora...
jgi:Cha6605_2766  217 piyqRKH---------------------------------------------SAQKFAALIHTTAnRK---------LMK 242  Chamaesip...
XP_002970976      216 ---------------------------------------------------YSRYNFYALFYNVTdVNVSs-----fDYG 239  Selaginel...
CCH31850          218 peweKAH--------------------------------------------PGREKFWHLVYDVPtEQ---------DMA 244  Saccharot...
Q5AV17            277 pnpgWTP--------------------------------------------TDPRKLWHIIYGVPqA----------EAA 302  Aspergill...
EHA25772          198 p-ndWTP--------------------------------------------KDPRKLWHIVYDVPeS----------AVS 222  Aspergill...
EPS26948          655 p-ndWPA--------------------------------------------KDPRKLWHIVYNVPeS----------AIS 679  Penicilli...
GAA87228          631 pnpdWTP--------------------------------------------SDPRKLWHIIYNVPsD----------SVG 656  Aspergill...
CBN79566          180 kvatTFTpitkkvtattkkkktwkmmlgcggdanavegpkvvegtppaappHVQGRAGFMVHGAArMSYEeiCH---WVN 256  Ectocarpu...
5D6T_A            238 QVRQ-----VADEIFITHLETd----------yYAGFG--GQWSE 265  Aspergillus clavatus NRRL 1
jgi:Ajs_0766      344 SANTpq--rNTGLVYATDRHYdyptn---tgnpWATLP--AYWEQ 381  Acidovorax sp. JS42
jgi:Cha6605_2766  243 STLDrvvkyKFSYVYITNDRPdtgd-----rnpWNTLP--EYWQA 280  Chamaesiphon minutus PCC 6605
XP_002970976      240 DVIDrayqqNVGWVYVTNDNLpn---------pWDTIA--SYFSG 273  Selaginella moellendorffii
CCH31850          245 AVVArskagGADYVYVTDRPFsp--------stWDFLT--SYWNA 279  Saccharothrix espanaensis DSM 44229
Q5AV17            303 RVANlaherGAGFIHITDDTLpn---------pYDTLPneAYMSA 338  Aspergillus nidulans
EHA25772          223 EVAKlanqrGAGFLQLTDDTLpn---------pYDTLPadSYIQS 258  Aspergillus niger ATCC 1015
EPS26948          680 EVIKlsqerGAGFIQLTDDLLpn---------pYDNLPsdSYVQS 715  Penicillium oxalicum 114-2
GAA87228          657 KVAElalkrGAGLIHITNDNLpn---------pYDTLPddDYMQV 692  Aspergillus kawachii IFO 4308
CBN79566          257 QLEDg----GWSHVYMTDKIYdpdsdnpahhnpWDAVP--TYWAD 295  Ectocarpus siliculosus
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap