Conserved Protein Domain Family
DUF3543

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pfam12063: DUF3543 
Domain of unknown function (DUF3543)
This presumed domain is functionally uncharacterized. This domain is found in eukaryotes. This domain is typically between 217 to 291 amino acids in length. This domain is found associated with pfam00069. This domain has a single completely conserved residue A that may be functionally important.
Statistics
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PSSM-Id: 403327
View PSSM: pfam12063
Aligned: 85 rows
Threshold Bit Score: 141.266
Threshold Setting Gi: 1249007148
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WGS:AAWC:PGTG_11663.3  793 VES--QLLAELEEFACKALVIIHFAD------QKL---AAI--------LPppp-------saSGPSASSTSNPAPfSGP 846  Pucc...
XP_002175351           574 GEA--ALIKSLEELSTKCNAVFRFAE------IKL---AQV----------------------ISPLAAESRIVEL-EAN 619  Schi...
XP_013025148           591 QTIdrTLMEVLENLAAKSNAVFHMAE------VKL---IQV--------LP----------------------------- 624  Schi...
Q9Y7T4                 594 K----RLLDVLESIAMKSNSVYHLAE------VKL---AQI--------IP----------------------------- 623  Schi...
XP_006675319           979 PQA--SFFSTLNLCALRAHAVNTLADgyfvelEKFttaKSLtqtgstptLPshq-------------------------- 1030 Batr...
EPT01989               603 MED--KLLATLEELAQKTEVLTHWAD------EMY---EYVk------aIP------------QKPLPDPTKFTRR-EGE 652  Fomi...
EKM78280               108 MED--ELLANLEELAQKTDVLTNWGD------EMY---EYVk------aIP------------QKPLPDPTKFTKR-EGE 157  Agar...
XP_003027013           621 RED--ALLEKLEVLAQKTEVLTNWAD------EMY---KCVv------eTR------------QNP-------------- 657  Schi...
P0CP70                 741 AED--DLLCTVEDLARKAFVLFELAD------ERLlaqTQLaqtartssTPtgl------tgtTPPFSMQAAAAAQ-AGS 805  Cryp...
Q4P0K0                 713 AEM--TLLSTLEDLGQKAFVLSEFAD------SKL---AHF--------FPdgphqlsqeldsSTATSGISPSRNSvQGS 773  Usti...
WGS:AAWC:PGTG_11663.3  847 VgafitSspssypsfDPsTsssstssssscydlrhsstldtpssvlskppsgqLAPAA---------------SALAAGQ 911  Pucc...
XP_002175351           620 A-----Q----------------------------------------------LPPGA---------------IASLCKE 633  Schi...
XP_013025148           625 Sl---eVddtqfdsmKDaR----------------------------------LTSAS---------------LVSLVKE 652  Schi...
Q9Y7T4                 624 Sl---sDemkpgdtlLDrP----------------------------------LTPFS---------------LVMLAKE 651  Schi...
XP_006675319          1031 -------------vqVQeS----------------------------------IVPSTlvdmrpfgraagqfnVATLADE 1063 Batr...
EPT01989               653 PerhaaKrknadiqaEYnA-----------------------------------------------------------MT 673  Fomi...
EKM78280               158 PekharKrkhadmeaEYnA-----------------------------------------------------------VT 178  Agar...
XP_003027013           658 S-----QrrdakseaEYnAvwlg---------------------------lagKNERS---------------LDLLQVT 690  Schi...
P0CP70                 806 RrksssSsmnsevwiLRqQ-------------------------------------------------------EAAAND 830  Cryp...
Q4P0K0                 774 ArrvgsIssss---------------------------------------ssaVDPVA---------------AEAASAE 799  Usti...
WGS:AAWC:PGTG_11663.3  912 ALLLYIKALAFLNKSIRHAVAVvdWKKLA---------------------VVGGGGNALSYETSCAIEWLRHKFNEVFDK 970  Pucc...
XP_002175351           634 AFVLYERDMELLQIGLDRIFAF----------------------------KAGNLEQSSSMPVQQSHDWFRRRYNESFEK 685  Schi...
XP_013025148           653 SLTLYQRDIELLQIAFDFVATV--WSNN---------------------------DEKNTSECREAMNWYQQRYAESLEK 703  Schi...
Q9Y7T4                 652 SYVLYERDIELLQVAFDGVAAF--WANS---------------------------EERASPDCQQAIEWFRQRYSESLEK 702  Schi...
XP_006675319          1064 TLTLYLHCLAQYQYAMELARKM--WDQERerltptqsmlisrfgfgipkpTATPGENNMLANLSVVVQWIRDRFNDCLSK 1141 Batr...
EPT01989               674 CVALYMLLMSFSQNGVNKLCNYyeh----------------------lqmRDPDGESEVSEGFDEALTYFEDHFNKCHDR 731  Fomi...
EKM78280               179 CVAVYMLLMSFSQKGINMLKQFqeh----------------------mgmKYPEDDYVVSEGFDDALNWFKEHFMKCNER 236  Agar...
XP_003027013           691 CVAVYLLLMGFAQKGIDELSLHqde----------------------mleDHPDAEYVVSEGFDDALCWFRERFLKCHER 748  Schi...
P0CP70                 831 AVVLYMKSLAFIVKAMDKVKRY--WKNRTdv------------------yD----GYVASQELNEMGQWLRARFNETFEK 886  Cryp...
Q4P0K0                 800 ALMLYVRSLAFLQRAITLTKRHve------------------------srSRPGVPAVTSAELNDVVQWLRARFNEVYDK 855  Usti...
WGS:AAWC:PGTG_11663.3  971 IQFVKTKAN----------------------------GKSLLSTGGRVlSADKLIYDRALEKSRSAAVNELGGD------ 1016 Pucc...
XP_002175351           686 SQFMREKYIsl-------------------------tTLHEIDDSDNI-EASHLIYNQALDMSRTAVTSELSGQ------ 733  Schi...
XP_013025148           704 TQFLKAVINsy-------------------------tFVNTQQTAKPT-FASQLIYQRALDISRNAATSELSGN------ 751  Schi...
Q9Y7T4                 703 SQFLREIIIsq-------------------------sAAHSLPTTKPV-SASQLIYHRALDLSRNAATSELSGN------ 750  Schi...
XP_006675319          1142 ADISRSRVGkhdnvgkqqgfvasitgdgitntalptrSSFTTTTLAPN-IAEKLIYDYAMHTSHQAAVQELHQT------ 1214 Batr...
EPT01989               732 AALVKTWLPaqyt--------------------------------gpptFLDQLIYDRALSLSKMAARKELTNE------ 773  Fomi...
EKM78280               237 AALVKTWLPaqyd--------------------------------gpkaWLDQLVYDRALVLSRTAARKELLDQ------ 278  Agar...
XP_003027013           749 AKLVKTWLPanyn--------------------------------gprtWLDQLVYDRALALSRLAARKELLDQ------ 790  Schi...
P0CP70                 887 AEWAKTQAGdt------------------------------------llFPDWLVHDKARDTSRQAAVAELQGD------ 924  Cryp...
Q4P0K0                 856 ADFARSRCSelpe---------------------------------saqQVDKLIFDKAVEVARAAATDELENNregsgw 902  Usti...
WGS:AAWC:PGTG_11663.3 1017 Sr-LKECELEYESSLWMLYGLM-----------------DERIIqTDSIfeldrpvlhphshtthphshphphtlrprka 1078 Pucc...
XP_002175351           734 D--LAKCLRMYEASNMLLESLL-----------------EGDLPsVNS-------------------------------- 762  Schi...
XP_013025148           752 D--LVNSLRSYKAASNLLESLL-----------------EGEFStPNG-------------------------------- 780  Schi...
Q9Y7T4                 751 D--AQACLQNYRLAAHLLESLL-----------------ESNFStPDG-------------------------------- 779  Schi...
XP_006675319          1215 G--MGRCEMLYQQAILLLESLLhvpprplsplpgvlahtDTDGHdGHGSqng---------------------------- 1264 Batr...
EPT01989               774 MssPDECEKLYEEALWCLYALQ-----------------DDLLQkDN--------------------------------- 803  Fomi...
EKM78280               279 AsaPDECEKLYEESLWCLYALQ-----------------DDLLQtGN--------------------------------- 308  Agar...
XP_003027013           791 AttPNECEKLYEESLWCLYALQ-----------------DELLQtGN--------------------------------- 820  Schi...
P0CP70                 925 ---LTTAEQGYETSLWLLQALL-----------------DESVYeNG--------------------------------- 951  Cryp...
Q4P0K0                 903 D--PSHCLLAYETANSMLSSLL-----------------DPGEDaM---------------------------------- 929  Usti...
WGS:AAWC:PGTG_11663.3 1079 evpvcgaeddlvddVADEQDRDNEEEeeddpiasqhkfikrscpnIIRSILVRLDSLRTKL 1139 Puccinia graminis f. sp...
XP_002175351           763 --------------TDESNDAPTIKK-------------------FIALIRRRHDLVAQKM 790  Schizosaccharomyces jap...
XP_013025148           781 --------------TEDFNNTFTIQK-------------------LTTLISKRLDLLQSKL 808  Schizosaccharomyces cry...
Q9Y7T4                 780 --------------ANDSNNSVTIRN-------------------LIALITKRQELLQSKQ 807  Schizosaccharomyces pom...
XP_006675319          1265 ------------eeELTDNDRIMIEK-------------------FLLGLYSRLDSLRT-- 1292 Batrachochytrium dendro...
EPT01989               804 --------------PYIEEDRETIST-------------------WIKRTKLRLVRCRVRM 831  Fomitopsis pinicola FP-...
EKM78280               309 --------------PFMEEDRETIAT-------------------WIKRTKLRLVRCRARM 336  Agaricus bisporus var. ...
XP_003027013           821 --------------ELLREDSETVAT-------------------WIKRTKLRLVRCRARM 848  Schizophyllum commune H4-8
P0CP70                 952 --------------SIPDEDKVAYDR-------------------LMVPIKTRLDALRKKL 979  Cryptococcus neoformans...
Q4P0K0                 930 --------------SLSEGSILMIDG-------------------YVKSINKRLWTLQEQF 957  Ustilago maydis 521
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